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  1. Book ; Thesis: Echokardiographische Kontrolle der mechanischen Vorhoftätigkeit nach Kardioversion

    Link-Eichhorn, Christian

    1997  

    Author's details vorgelegt von Christian Link-Eichhorn
    Language German
    Size 55 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 1998
    HBZ-ID HT009720072
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Multiparametric Cardiovascular Magnetic Resonance Approach in Diagnosing, Monitoring, and Prognostication of Myocarditis.

    Eichhorn, Christian / Greulich, Simon / Bucciarelli-Ducci, Chiara / Sznitman, Raphael / Kwong, Raymond Y / Gräni, Christoph

    JACC. Cardiovascular imaging

    2022  Volume 15, Issue 7, Page(s) 1325–1338

    Abstract: Myocarditis represents the entity of an inflamed myocardium and is a diagnostic challenge caused by its heterogeneous presentation. Contemporary noninvasive evaluation of patients with clinically suspected myocarditis using cardiac magnetic resonance ( ... ...

    Abstract Myocarditis represents the entity of an inflamed myocardium and is a diagnostic challenge caused by its heterogeneous presentation. Contemporary noninvasive evaluation of patients with clinically suspected myocarditis using cardiac magnetic resonance (CMR) includes dimensions and function of the heart chambers, conventional T2-weighted imaging, late gadolinium enhancement, novel T1 and T2 mapping, and extracellular volume fraction calculation. CMR feature-tracking, texture analysis, and artificial intelligence emerge as potential modern techniques to further improve diagnosis and prognostication in this clinical setting. This review describes the evidence surrounding different CMR methods and image postprocessing methods and highlights their values for clinical decision making, monitoring, and risk stratification across stages of this condition.
    MeSH term(s) Artificial Intelligence ; Contrast Media ; Gadolinium ; Humans ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging, Cine/methods ; Magnetic Resonance Spectroscopy ; Myocarditis/pathology ; Myocardium/pathology ; Predictive Value of Tests
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2021.11.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: EnvSLAM: Combining SLAM Systems and Neural Networks to Improve the Environment Fusion in AR Applications

    Marchesi, Giulia / Eichhorn, Christian / Plecher, David A. / Itoh, Yuta / Klinker, Gudrun

    ISPRS international journal of geo-information. 2021 Nov. 12, v. 10, no. 11

    2021  

    Abstract: Augmented Reality (AR) has increasingly benefited from the use of Simultaneous Localization and Mapping (SLAM) systems. This technology has enabled developers to create AR markerless applications, but lack semantic understanding of their environment. The ...

    Abstract Augmented Reality (AR) has increasingly benefited from the use of Simultaneous Localization and Mapping (SLAM) systems. This technology has enabled developers to create AR markerless applications, but lack semantic understanding of their environment. The inclusion of this information would empower AR applications to better react to the surroundings more realistically. To gain semantic knowledge, in recent years, focus has shifted toward fusing SLAM systems with neural networks, giving birth to the field of Semantic SLAM. Building on existing research, this paper aimed to create a SLAM system that generates a 3D map using ORB-SLAM2 and enriches it with semantic knowledge originated from the Fast-SCNN network. The key novelty of our approach is a new method for improving the predictions of neural networks, employed to balance the loss of accuracy introduced by efficient real-time models. Exploiting sensor information provided by a smartphone, GPS coordinates are utilized to query the OpenStreetMap database. The returned information is used to understand which classes are currently absent in the environment, so that they can be removed from the network’s prediction with the goal of improving its accuracy. We achieved 87.40% Pixel Accuracy with Fast-SCNN on our custom version of COCO-Stuff and showed an improvement by involving GPS data for our self-made smartphone dataset resulting in 90.24% Pixel Accuracy. Having in mind the use on smartphones, the implementation aimed to find a trade-off between accuracy and efficiency, making the system achieve an unprecedented speed. To this end, the system was carefully designed and a strong focus on lightweight neural networks is also fundamental. This enabled the creation of an above real-time Semantic SLAM system that we called EnvSLAM (Environment SLAM). Our extensive evaluation reveals the efficiency of the system features and the operability in above real-time (48.1 frames per second with an input image resolution of 640 × 360 pixels). Moreover, the GPS integration indicates an effective improvement of the network’s prediction accuracy.
    Keywords augmented reality ; data collection ; databases ; digital images ; mobile telephones ; prediction ; spatial data
    Language English
    Dates of publication 2021-1112
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2655790-3
    ISSN 2220-9964
    ISSN 2220-9964
    DOI 10.3390/ijgi10110772
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Out-of-hospital cardiac arrest and survival in a patient with Noonan syndrome and multiple lentigines: a case report.

    Eichhorn, Christian / Voges, Inga / Daubeney, Piers E F

    Journal of medical case reports

    2019  Volume 13, Issue 1, Page(s) 194

    Abstract: Background: A 9-year-old Arabic boy attending middle school presented with an out-of-hospital cardiac arrest due to ventricular fibrillation recorded by Holter electrocardiographic monitoring. He had a background history of Noonan syndrome with multiple ...

    Abstract Background: A 9-year-old Arabic boy attending middle school presented with an out-of-hospital cardiac arrest due to ventricular fibrillation recorded by Holter electrocardiographic monitoring. He had a background history of Noonan syndrome with multiple lentigines (also known as LEOPARD syndrome), a rare condition of autosomal dominant inheritance with approximately 200 cases reported worldwide.
    Case presentation: Apart from characteristic features, the boy was known to have asymmetric septal hypertrophy with a maximum wall thickness of 24 mm measured by cardiovascular magnetic resonance imaging. A day prior to the event, he attended cardiology follow-up at our institution, and Holter monitoring was commenced. Following cardiopulmonary resuscitation by bystanders and paramedics, he reverted back into sinus rhythm after a total downtime of 24 min. He was initially treated in the intensive care unit and underwent implantable cardioverter defibrillator implantation. He has made a full recovery and remains at the top of his class.
    Conclusion: This case demonstrates that sudden cardiac arrest in patients with secondary forms of hypertrophic cardiomyopathy is not necessarily protected by apparently favorable phenotypes and that events may be preceded by non-sustained ventricular tachycardia observed by Holter monitoring. Implantable cardioverter defibrillator implantation plays a critical role in both primary and secondary prevention in patients at high risk of out-of-hospital cardiac arrest.
    MeSH term(s) Cardiopulmonary Resuscitation ; Child ; Defibrillators, Implantable ; Humans ; LEOPARD Syndrome/complications ; Male ; Noonan Syndrome/complications ; Out-of-Hospital Cardiac Arrest/etiology ; Out-of-Hospital Cardiac Arrest/therapy
    Language English
    Publishing date 2019-06-15
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-019-2096-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cerebrospinal fluid and venous biomarkers of shunt-responsive idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis.

    Thavarajasingam, Santhosh G / El-Khatib, Mahmoud / Vemulapalli, Kalyan V / Iradukunda, Hector A Sinzinkayo / Laleye, Joshua / Russo, Salvatore / Eichhorn, Christian / Eide, Per K

    Acta neurochirurgica

    2022  Volume 164, Issue 7, Page(s) 1719–1746

    Abstract: Background: Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative disease and dementia subtype involving disturbed cerebrospinal fluid (CSF) homeostasis. Patients with iNPH may improve clinically following CSF diversion through shunt ... ...

    Abstract Background: Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative disease and dementia subtype involving disturbed cerebrospinal fluid (CSF) homeostasis. Patients with iNPH may improve clinically following CSF diversion through shunt surgery, but it remains a challenge to predict which patients respond to shunting. It has been proposed that CSF and blood biomarkers may be used to predict shunt response in iNPH.
    Objective: To conduct a systematic review and meta-analysis to identify which CSF and venous biomarkers predict shunt-responsive iNPH most accurately.
    Methods: Original studies that investigate the use of CSF and venous biomarkers to predict shunt response were searched using the following databases: Embase, MEDLINE, Scopus, PubMed, Google Scholar, and JSTOR. Included studies were assessed using the ROBINS-I tool, and eligible studies were evaluated utilising univariate meta-analyses.
    Results: The study included 13 studies; seven addressed lumbar CSF levels of amyloid-β 1-42, nine studies CSF levels of Total-Tau, six studies CSF levels of Phosphorylated-Tau, and seven studies miscellaneous biomarkers, proteomics, and genotyping. A meta-analysis of six eligible studies conducted for amyloid-β 1-42, Total-Tau, and Phosphorylated-Tau demonstrated significantly increased lumbar CSF Phosphorylated-Tau (- 0.55 SMD, p = 0.04) and Total-Tau (- 0.50 SMD, p = 0.02) in shunt-non-responsive iNPH, though no differences were seen between shunt responders and non-responders for amyloid-β 1-42 (- 0.26 SMD, p = 0.55) or the other included biomarkers.
    Conclusion: This meta-analysis found that lumbar CSF levels of Phosphorylated-Tau and Total-Tau are significantly increased in shunt non-responsive iNPH compared to shunt-responsive iNPH. The other biomarkers, including amyloid-β 1-42, did not significantly differentiate shunt-responsive from shunt-non-responsive iNPH. More studies on the Tau proteins examining sensitivity and specificity at different cut-off levels are needed for a robust analysis of the diagnostic efficiency of the Tau proteins.
    MeSH term(s) Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Humans ; Hydrocephalus, Normal Pressure/cerebrospinal fluid ; Hydrocephalus, Normal Pressure/diagnosis ; Hydrocephalus, Normal Pressure/surgery ; Neurodegenerative Diseases ; tau Proteins/cerebrospinal fluid
    Chemical Substances Amyloid beta-Peptides ; Biomarkers ; tau Proteins
    Language English
    Publishing date 2022-03-01
    Publishing country Austria
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05154-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Automatische Duplikatserkennung

    Eichhorn, Christian

    ähnliche Texte entdecken und erkennen

    2009  

    Title variant Automatische Erkennung von Duplikaten in Textbeständen mit Hilfe flacher Verfahren
    Author's details Christian Eichhorn
    Language German
    Size XI, 144 S., graph. Darst., 210 mm x 150 mm
    Publisher Der Andere Verlag
    Publishing place Tönning u.a.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Univ., Diplomarbeit. u.d.T.:Eichhorn, Christian: Automatische Erkennung von Duplikaten in Textbeständen mit Hilfe flacher Verfahren--Dortmund, 2009
    Note Literaturverz. S. 123 -127
    ISBN 9783899599251 ; 389959925X
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Online ; Thesis: Ruthenium-Thioaldehyd-Komplexe

    Eichhorn, Christian

    Synthese, Struktur und C-C-Verknüpfungsreaktionen

    2003  

    Author's details vorgelegt von Christian Eichhorn
    Keywords Rutheniumkomplexe ; Kupplungsreaktion ; Thioaldehyde
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., Diss--Würzburg, 2003
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article ; Online: Long-term cardiovascular outcomes after orlistat therapy in patients with obesity: a nationwide, propensity-score matched cohort study.

    Ardissino, Maddalena / Vincent, Matthew / Hines, Oliver / Amin, Ravi / Eichhorn, Christian / Tang, Alice R / Collins, Peter / Moussa, Osama / Purkayastha, Sanjay

    European heart journal. Cardiovascular pharmacotherapy

    2021  Volume 8, Issue 2, Page(s) 179–186

    Abstract: Aims: The rising prevalence of obesity and its associated comorbidities represent a growing public health issue; in particular, obesity is known to be a major risk factor for cardiovascular disease. Despite the evidence behind the efficacy of orlistat ... ...

    Abstract Aims: The rising prevalence of obesity and its associated comorbidities represent a growing public health issue; in particular, obesity is known to be a major risk factor for cardiovascular disease. Despite the evidence behind the efficacy of orlistat in achieving weight loss in patients with obesity, no study thus far has quantified its long-term effect on cardiovascular outcomes. The purpose of this study is to explore long-term cardiovascular outcomes after orlistat therapy.
    Methods and results: A propensity-score matched cohort study was conducted on the nation-wide electronic primary and integrated secondary healthcare records of the Clinical Practice Research Datalink (CPRD). The 36 876 patients with obesity in the CPRD database who had completed a course of orlistat during follow-up were matched on a 1:1 basis with equal numbers of controls who had not taken orlistat. Patients were followed up for a median of 6 years for the occurrence of the primary composite endpoint of major adverse cardiovascular events (fatal or non-fatal myocardial infarction or ischaemic stroke), and a number of secondary endpoints including primary endpoint components individually, the occurrence of new-onset heart failure, coronary revascularization, new chronic kidney disease stage III+ (CKD3+), and all-cause mortality. During the median study follow-up of 6 years, the occurrence of major adverse cardiovascular events was lower in the orlistat cohort [hazard ratio (HR) 0.74; 95% confidence interval (CI) 0.66-0.83, P < 0.001]. Patients who took orlistat experienced lower rates of myocardial infarction (HR 0.77; 95% CI 0.66-0.88, P < 0.001) and ischaemic stroke (HR 0.68; 95% CI 0.56 to -0.84, P < 0.001) as well as new-onset heart failure (HR 0.79; 95% CI 0.67-0.94, P = 0.007). There was no differences in revascularization rates (HR 1.12; 95% CI 0.91-1.38, P = 0.27), but a lower rate of both CKD3+ development (HR 0.78; 95% CI 0.73-0.83, P < 0.001) and mortality (HR 0.39, 95% CI 0.36 to -0.41, P < 0.001) was observed.
    Conclusion: In this nation-wide, propensity-score matched study, orlistat was associated with lower rates of overall major adverse cardiovascular events, new-onset heart failure, renal failure, and mortality. This study adds to current evidence on the known improvements in cardiovascular risk factor profiles of orlistat treatment by suggesting a potential role in primary prevention.
    MeSH term(s) Brain Ischemia/chemically induced ; Brain Ischemia/epidemiology ; Brain Ischemia/etiology ; Cardiovascular Diseases/chemically induced ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cohort Studies ; Humans ; Obesity/complications ; Obesity/diagnosis ; Obesity/drug therapy ; Obesity/epidemiology ; Orlistat/adverse effects ; Stroke/chemically induced ; Stroke/epidemiology ; Stroke/etiology
    Chemical Substances Orlistat (95M8R751W8)
    Language English
    Publishing date 2021-05-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2808613-2
    ISSN 2055-6845 ; 2055-6837
    ISSN (online) 2055-6845
    ISSN 2055-6837
    DOI 10.1093/ehjcvp/pvaa133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Atrial fibrillation and obesity: Long-term incidence and outcomes after bariatric surgery.

    Moussa, Osama / Ardissino, Maddalena / Eichhorn, Christian / Reddy, Rohin K / Khan, Omar / Ziprin, Paul / Darzi, Ara / Collins, Peter / Purkayastha, Sanjay

    European journal of preventive cardiology

    2020  Volume 28, Issue 9, Page(s) e22–e24

    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/etiology ; Bariatric Surgery/adverse effects ; Humans ; Incidence ; Obesity/complications ; Obesity/epidemiology ; Obesity/surgery
    Language English
    Publishing date 2020-01-29
    Publishing country England
    Document type Letter
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1177/2047487320904515
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Conference proceedings: Forschungsprojekt ‚ReduSys‘: Kontaktreduzierte Pflege im klinischen Umfeld durch multimodale Systeme und Robotik

    Buetikofer, Alisa / Bloemeke, Svenja / Müller, Friedemann / Schneider, Carolin / Ohneberg, Christoph / Eberl, Ingeborg / Schmailzl, Marc / Linner, Thomas / Grabig, Sylvia / Hostettler, Rafael / Eichhorn, Christian / Klinker, Gudrun

    2023  , Page(s) 23ebmPSI–3–07

    Event/congress 24. Jahrestagung des Netzwerks Evidenzbasierte Medizin; Gesundheit und Klima – EbM für die Zukunft; Potsdam; Netzwerk Evidenzbasierte Medizin e.V.; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-03-21
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23ebm048
    Database German Medical Science

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