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  1. AU="El Kamouni, Soufiane"
  2. AU="Ishisaka, Takuya"
  3. AU="Gábor Bedics"
  4. AU=Nipp Ryan D.
  5. AU="Lucero, D E"
  6. AU="Isik, C"
  7. AU="Lange, Lana"
  8. AU="Morris, Ray"
  9. AU="Sun, Xiankai"
  10. AU=Jeggo Penny A.
  11. AU="Kanthamneni, Naveen"
  12. AU="Di Lorenzo, Raffaele"
  13. AU="Tiraboschi, Juan M"
  14. AU="Xiang, Jinzhu"
  15. AU="Diehl, Kyra"
  16. AU="Aparicio-Yuste, Raul"
  17. AU="Jiang, Gengbo"
  18. AU=Murrell Dedee F AU=Murrell Dedee F
  19. AU=Gupta Riya
  20. AU="Elmasry, Dalia M A" AU="Elmasry, Dalia M A"
  21. AU=Rosa Rafael Fabiano Machado
  22. AU="Bhatia, Vishwas"
  23. AU="Buchwitz, Michael"
  24. AU="Sadrozinski, H-F W."
  25. AU="Allan, Rachel"
  26. AU="Ma, Jiele"
  27. AU="Bizjak, Isabella"
  28. AU="Pelucchi, Paride"
  29. AU="Krug, Anne Barbara"
  30. AU="Pikridas, M"
  31. AU="Adams, Jonathan D"
  32. AU="Esquivel-Muelbert, A."
  33. AU="Khan, Meraj Alam"
  34. AU="Bullard, Stevan"
  35. AU="Wang, Peter H"
  36. AU="Preto, Jordane"
  37. AU="Pierce, Shaketha"
  38. AU="Sankar, Jishnu"
  39. AU="Yahagi, Naohisa"
  40. AU=Pinho Juliana
  41. AU="Brennan, Anna"
  42. AU="Lee, Theresa M"
  43. AU="Chunqing Ou"
  44. AU="Gwynn, Simon"
  45. AU="Holper, Sarah"
  46. AU="Haider, Farag Ibrahim"
  47. AU="Rice, Jordin L"
  48. AU="Gong, Xingguo"
  49. AU=Rother Magdalena B.
  50. AU="Petrov, Ksenia"
  51. AU="Rijneveld, R"
  52. AU=Lopez-Martinez Briceida
  53. AU=Astone Pia
  54. AU="Amaral, V"

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  1. Artikel ; Online: Antioxidant Effects of Argan Oil and Olive Oil against Iron-Induced Oxidative Stress: In Vivo and In Vitro Approaches.

    Bouchab, Habiba / Essadek, Soukaina / El Kamouni, Soufiane / Moustaid, Khadija / Essamadi, Abdelkhalid / Andreoletti, Pierre / Cherkaoui-Malki, Mustapha / El Kebbaj, Riad / Nasser, Boubker

    Molecules (Basel, Switzerland)

    2023  Band 28, Heft 15

    Abstract: Recently, the study of the protective powers of medicinal plants has become the focus of several studies. Attention has been focused on the identification of new molecules with antioxidant and chelating properties to counter reactive oxygen species (ROS) ...

    Abstract Recently, the study of the protective powers of medicinal plants has become the focus of several studies. Attention has been focused on the identification of new molecules with antioxidant and chelating properties to counter reactive oxygen species (ROS) involved as key elements in several pathologies. Considerable attention is given to argan oil (AO) and olive oil (OO) due to their particular composition and preventive properties. Our study aimed to determine the content of AO and OO on phenolic compounds, chlorophylls, and carotenoid pigments and their antioxidant potential by FRAP and DPPH tests. Thus, several metallic elements can induce oxidative stress, as a consequence of the formation of ROS. Iron is one of these metal ions, which participates in the generation of free radicals, especially OH from H
    Mesh-Begriff(e) Mice ; Animals ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Olive Oil/pharmacology ; Reactive Oxygen Species/metabolism ; Iron/pharmacology ; Hydrogen Peroxide/pharmacology ; Plant Oils/pharmacology ; Plant Oils/chemistry ; Oxidative Stress ; Lipid Peroxidation ; Glutathione/metabolism ; Phenols/pharmacology ; Superoxide Dismutase/metabolism
    Chemische Substanzen Antioxidants ; argan oil (4V59G5UW9X) ; Olive Oil ; Reactive Oxygen Species ; Iron (E1UOL152H7) ; Hydrogen Peroxide (BBX060AN9V) ; Plant Oils ; Glutathione (GAN16C9B8O) ; Phenols ; Superoxide Dismutase (EC 1.15.1.1)
    Sprache Englisch
    Erscheinungsdatum 2023-08-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28155924
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.MO 81: Hefte anzeigen

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  2. Artikel: Effects of a Short-Term Lipopolysaccharides Challenge on Mouse Brain and Liver Peroxisomal Antioxidant and β-oxidative Functions: Protective Action of Argan Oil.

    Essadek, Soukaina / Bouchab, Habiba / El Kebbaj, Riad / Gondcaille, Catherine / El Kamouni, Soufiane / Savary, Stéphane / Vamecq, Joseph / Essamadi, Abdelkhalid / Cherkaoui-Malki, Mustapha / Nasser, Boubker / Andreoletti, Pierre

    Pharmaceuticals (Basel, Switzerland)

    2022  Band 15, Heft 4

    Abstract: During sepsis, the imbalance between oxidative insult and body antioxidant response causes the dysfunction of organs, including the brain and liver. Exposing mice to bacterial lipopolysaccharides (LPS) results in a similar pathophysiological outcome. The ...

    Abstract During sepsis, the imbalance between oxidative insult and body antioxidant response causes the dysfunction of organs, including the brain and liver. Exposing mice to bacterial lipopolysaccharides (LPS) results in a similar pathophysiological outcome. The protection offered by argan oil was studied against LPS-induced oxidative stress, dysregulation of peroxisomal antioxidants, and β-oxidation activities in the brain and liver. In a short-term LPS treatment, lipid peroxidation (malonaldehyde assay) increased in the brain and liver with upregulations of proinflammatory
    Sprache Englisch
    Erscheinungsdatum 2022-04-12
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph15040465
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: Protective Effect of Argan and Olive Oils against LPS-Induced Oxidative Stress and Inflammation in Mice Livers.

    El Kamouni, Soufiane / El Kebbaj, Riad / Andreoletti, Pierre / El Ktaibi, Abderrahim / Rharrassi, Issam / Essamadi, Abdelkhalid / El Kebbaj, M'hammed Saïd / Mandard, Stéphane / Latruffe, Norbert / Vamecq, Joseph / Nasser, Boubker / Cherkaoui-Malki, Mustapha

    International journal of molecular sciences

    2017  Band 18, Heft 10

    Abstract: Sepsis causes severe dysregulation of organ functions, via the development of oxidative stress and inflammation. These pathophysiological mechanisms are mimicked in mice injected with bacterial lipopolysaccharide (LPS). Here, protective properties of ... ...

    Abstract Sepsis causes severe dysregulation of organ functions, via the development of oxidative stress and inflammation. These pathophysiological mechanisms are mimicked in mice injected with bacterial lipopolysaccharide (LPS). Here, protective properties of argan oil against LPS-induced oxidative stress and inflammation are explored in the murine model. Mice received standard chow, supplemented with argan oil (AO) or olive oil (OO) for 25 days, before septic shock was provoked with a single intraperitoneal injection of LPS, 16 hours prior to animal sacrifice. In addition to a rise in oxidative stress and inflammatory markers, injected LPS also caused hepatotoxicity, accompanied by hyperglycemia, hypercholesterolemia and hyperuremia. These LPS-associated toxic effects were blunted by AO pretreatment, as corroborated by normal plasma parameters and cell stress markers (glutathione: GSH) and antioxidant enzymology (catalase, CAT; superoxide dismutase, SOD and glutathione peroxidase, GPx). Hematoxylin-eosin staining revealed that AO can protect against acute liver injury, maintaining a normal status, which is pointed out by absent or reduced LPS-induced hepatic damage markers (i.e., alanine aminotransferase (ALT) and aspartate transaminase (AST)). Our work also indicated that AO displayed anti-inflammatory activity, due to down-regulations of genes encoding pro-inflammatory cytokines Interleukin-6 (IL-6) and Tumor Necrosis Factor-α (TNF-α) and in up-regulations of the expression of anti-inflammatory genes encoding Interleukin-4 (IL-4) and Interleukin-10 (IL-10). OO provided animals with similar, though less extensive, protective changes. Collectively our work adds compelling evidence to the protective mechanisms of AO against LPS-induced liver injury and hence therapeutic potentialities, in regard to the management of human sepsis. Activations of IL-4/Peroxisome Proliferator-Activated Receptors (IL-4/PPARs) signaling and, under LPS, an anti-inflammatory IL-10/Liver X Receptor (IL-10/LXR) route, obviously indicated the high potency and plasticity of the anti-inflammatory properties of argan oil.
    Mesh-Begriff(e) Animals ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antioxidants/administration & dosage ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Dietary Supplements ; Lipopolysaccharides/toxicity ; Liver/drug effects ; Liver/metabolism ; Liver Diseases/drug therapy ; Liver Diseases/etiology ; Liver Diseases/prevention & control ; Mice ; Olive Oil/administration & dosage ; Olive Oil/pharmacology ; Olive Oil/therapeutic use ; Oxidative Stress ; Plant Oils/administration & dosage ; Plant Oils/pharmacology ; Plant Oils/therapeutic use
    Chemische Substanzen Anti-Inflammatory Agents ; Antioxidants ; Lipopolysaccharides ; Olive Oil ; Plant Oils ; argan oil (4V59G5UW9X)
    Sprache Englisch
    Erscheinungsdatum 2017-10-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms18102181
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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