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  1. Article ; Online: Evaluation of surface microhardness and gingival marginal adaptation of three different bulk-fill flowable resin composites: A comparative study.

    Khairy, Nourhan Medhat / Elkholany, Naglaa Rizk / Elembaby, Abeer Elsayed

    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.

    2024  Volume 36, Issue 6, Page(s) 920–929

    Abstract: Objectives: To evaluate surface microhardness and gingival marginal adaptation of three different bulk-fill flowable resin composites (FB-RBCs) in Class V cavities with enamel or dentin margins before and after thermocycling (TMC).: Materials and ... ...

    Abstract Objectives: To evaluate surface microhardness and gingival marginal adaptation of three different bulk-fill flowable resin composites (FB-RBCs) in Class V cavities with enamel or dentin margins before and after thermocycling (TMC).
    Materials and methods: Three available FB-RBCs were used; Palfique Bulk Flow (PaBF) (Tokuyama Dental), SDR Flow+ Bulk Fill Flowable (Dentsply Sirona), and I-Flow Bulk Fill (I-Dental). Thirty discs were prepared from each type of FB-RBCs. The discs were subjected to Vickers microhardness tester machine. Class V cavities were prepared on 180 molars. Gingival margins of half the specimens were prepared above CEJ and the other half below CEJ. Cavities were restored with FB-RBCs for gingival marginal adaptation test. Two-way ANOVA was used in microhardness, while three-way ANOVA was used for marginal adaptation.
    Results: The used materials showed statistically significant differences in microhardness and marginal adaptation.
    Conclusions: Regarding microhardness, PaBF showed the highest value before TMC and SDR was the highest after TMC. Regarding marginal adaptation, SDR revealed the best marginal adaptation than PaBF and I-flow, either subjected to TMC or not.
    Clinical significance: The longevity of cervical restorations depend on both the location of the cavity margin and the material used. The microfractures in resin composite surface due to low surface microhardness as well as marginal gaps seen in laboratory studies could be considered as an indicative parameter for clinical problem associated with marginal differences.
    MeSH term(s) Composite Resins/chemistry ; Humans ; Hardness ; Surface Properties ; Dental Marginal Adaptation ; Gingiva ; Materials Testing ; Dental Restoration, Permanent/methods
    Chemical Substances Composite Resins
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article ; Comparative Study
    ZDB-ID 2043146-6
    ISSN 1708-8240 ; 1496-4155
    ISSN (online) 1708-8240
    ISSN 1496-4155
    DOI 10.1111/jerd.13211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3314: Show issues Location:
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  2. Article ; Online: The Impact of Nano-Hydroxyapatite Resin Infiltrant on Enamel Remineralization: An In Vitro Study.

    Elembaby, Abeer / AlHumaid, Jehan / El Tantawi, Maha / Akhtar, Sultan

    The International journal of periodontics & restorative dentistry

    2022  Volume 42, Issue 2, Page(s) e43–e50

    Abstract: This study assessed the effect of nano-hydroxyapatite incorporation into resin infiltrant on the mineral content, surface tomography, and resin tag penetration of demineralized enamel. Forty specimens were exposed to a demineralized solution to form ... ...

    Abstract This study assessed the effect of nano-hydroxyapatite incorporation into resin infiltrant on the mineral content, surface tomography, and resin tag penetration of demineralized enamel. Forty specimens were exposed to a demineralized solution to form subsurface caries lesions. The lesions were treated with negative control, a resin infiltrant (ICON), ICON with 5% nano-hydroxyapatite (NHA, Sigma-Aldrich), or ICON with 10% NHA. Mineral density was assessed using microcomputed tomography scans at various stages of the experiment. Specimens were scanned by scanning electron microscope (SEM) for surface analysis and resin tag penetration. Analysis of variance was used to assess the difference among groups. Specimens treated with ICON and 5% or 10% NHA showed the most favorable mineral density regarding the percent change in mineral content (32.4% and 29.7%, respectively), compared to 8.8% in teeth treated with ICON alone and -1.8% in teeth in the control group. SEM showed that teeth treated with ICON or ICON with 5% or 10% NHA had a smooth surface. The resin penetration in all tested groups showed high-quality resin tags, regardless of the treatment protocol. NHA resin infiltrant (ICON with 5% or 10% NHA) effectively enhanced the artificial enamel caries surfaces in terms of smooth surfaces, mineral density, and resin penetration.
    MeSH term(s) Dental Caries/drug therapy ; Dental Enamel ; Durapatite/therapeutic use ; Humans ; Tooth Remineralization ; X-Ray Microtomography
    Chemical Substances Durapatite (91D9GV0Z28)
    Language English
    Publishing date 2022-03-30
    Publishing country United States
    Document type Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.5599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Matrix Metalloproteinases in Dental and Periodontal Tissues and Their Current Inhibitors: Developmental, Degradational and Pathological Aspects.

    Elgezawi, Moataz / Haridy, Rasha / Almas, Khalid / Abdalla, Moamen A / Omar, Omar / Abuohashish, Hatem / Elembaby, Abeer / Christine Wölfle, Uta / Siddiqui, Yasir / Kaisarly, Dalia

    International journal of molecular sciences

    2022  Volume 23, Issue 16

    Abstract: Objectives: This review article aims to describe some of the roles of Matrix metalloproteinases (MMPs) in enamel, dentine, dental caries, hybrid layer degradation, pulp and periodontal tissues, throwing light on their current inhibitors. The article ... ...

    Abstract Objectives: This review article aims to describe some of the roles of Matrix metalloproteinases (MMPs) in enamel, dentine, dental caries, hybrid layer degradation, pulp and periodontal tissues, throwing light on their current inhibitors. The article addresses the potential of MMPs to serve as biomarkers with diagnostic and therapeutic value.
    Design: The sections of this review discuss MMPs' involvement in developmental, remodeling, degradational and turnover aspects of dental and periodontal tissues as well as their signals in the pathogenesis, progress of different lesions and wound healing of these tissues. The literature was searched for original research articles, review articles and theses. The literature search was conducted in PubMed and MEDLINE for articles published in the last 20 years.
    Results: 119 published papers, two textbooks and two doctoral theses were selected for preparing the current review.
    Conclusions: MMPs are significant proteases, of evident contribution in dental and periapical tissue development, health and disease processes, with promising potential for use as diagnostic and prognostic disease biomarkers. Continuing understanding of their role in pathogenesis and progress of different dental, periapical and periodontal lesions, as well as in dentine-pulp wound healing could be a keystone to future diagnostic and therapeutic regimens.
    MeSH term(s) Biomarkers ; Dental Caries ; Humans ; Matrix Metalloproteinases/metabolism ; Periodontium/metabolism
    Chemical Substances Biomarkers ; Matrix Metalloproteinases (EC 3.4.24.-)
    Language English
    Publishing date 2022-08-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23168929
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  4. Article ; Online: X-ray microtomography assessment of Carisolv and Papacarie effect on dentin mineral density and amount of removed tissue.

    AlHumaid, Jehan / Al-Harbi, Fahad / El Tantawi, Maha / Elembaby, Abeer

    Acta odontologica Scandinavica

    2017  Volume 76, Issue 4, Page(s) 236–240

    Abstract: Objective: The aim of the present study was to directly compare Carisolv and Papacarie regarding the volume of removed tissue (RT) and dentin mineral density (DMD) after excavation.: Materials and methods: Twenty permanent molars were randomized into ...

    Abstract Objective: The aim of the present study was to directly compare Carisolv and Papacarie regarding the volume of removed tissue (RT) and dentin mineral density (DMD) after excavation.
    Materials and methods: Twenty permanent molars were randomized into two groups where caries was excavated using Carisolv or Papacarie followed by removal of softened tissue by a blunt instrument. X-ray microtomography was used to scan teeth before and after excavation generating two- and three-dimensional images that were used to calculate the percentage of RT relative to baseline tooth tissue volume and DMD that was categorized into sound dentin (>1.11 g/cm
    Results: DMD was higher after Papacarie than Carisolv (mean = 1.70 and 1.14, p = .14) with higher percentage of cases with sound dentin (70 and 60%, p = 1.00). The percentage of RT was lower after Papacarie than Carisolv (7.40 and 8.95%, p = .31) with 22.95% less RT in cases that ended with sound dentin after excavation.
    Conclusions: There was higher DMD, more sound dentin and less RT when Papacarie was used compared to Carisolv.
    MeSH term(s) Dental Caries/diagnostic imaging ; Dental Cavity Preparation/methods ; Dentin/diagnostic imaging ; Glutamic Acid/administration & dosage ; Humans ; Leucine/administration & dosage ; Lysine/administration & dosage ; Molar ; Papain/administration & dosage ; Random Allocation ; Solvents/therapeutic use ; X-Ray Microtomography
    Chemical Substances Carisolv ; Papacarie ; Solvents ; Glutamic Acid (3KX376GY7L) ; Papain (EC 3.4.22.2) ; Leucine (GMW67QNF9C) ; Lysine (K3Z4F929H6)
    Language English
    Publishing date 2017-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 210362-x
    ISSN 1502-3850 ; 0001-6357
    ISSN (online) 1502-3850
    ISSN 0001-6357
    DOI 10.1080/00016357.2017.1406614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul III Zs.110: Show issues Location:
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  5. Article ; Online: Apoptotic effect of different self-etch dental adhesives on odontoblasts in cell cultures.

    El-kholany, Naglaa R / Abielhassan, Mohsen H / Elembaby, Abeer E / Maria, Ola M

    Archives of oral biology

    2012  Volume 57, Issue 6, Page(s) 775–783

    Abstract: Objectives: We aimed to evaluate the potential cytotoxicity (apoptosis-induction) of three types of self-etch dental adhesives: two-component one-step (Xeno III), two-component two-steps (Clearfil Protect Bond) and one-component one-step (Xeno V) on ... ...

    Abstract Objectives: We aimed to evaluate the potential cytotoxicity (apoptosis-induction) of three types of self-etch dental adhesives: two-component one-step (Xeno III), two-component two-steps (Clearfil Protect Bond) and one-component one-step (Xeno V) on cultured odontoblasts.
    Methods: Each adhesive was prepared to simulate its clinical manipulation. Cured sterile individual masses were immersed in DMEM and left at 37 °C for 24 h. Then a volume of 100 μL of the extract medium was added to the cultured odontoblasts and incubated for additional 24 h, 48 h and 72 h, respectively. Acridine orange-propidium iodide (AO-PI) labelling was employed to assess the proportion of dead to total number of cells. In addition, an in situ apoptosis detection kit was used to evaluate the DNA cleavage and chromatin condensation employing the immunohistochemical (IHC) technique. Statistical analysis of the data was performed using one-way ANOVA.
    Results: Both apoptosis evaluation methods revealed comparable results with the exception that IHC showed 5-7% less number of dead cells when compared to similar groups evaluated by AO-PI. The percentages of dead to total cells after treatment with Clearfil Protect Bond, Xeno III and Xeno V, were significantly different from the percentage of dead cells after treatment with DMEM alone (-ve control), P value <0.05 and Xeno V dental adhesive had the weakest cytotoxic effect on odontoblasts followed by Xeno III especially after 24 h of incubation. Clearfil Protect Bond had the strongest cytotoxic effect on odontoblasts that was almost closer to that of Staurosporine in DMEM (+ve control).
    Conclusion: All tested dental adhesives had remarkable adverse effect on the odontoblasts in vitro; this might be of concern when applied clinically in deep cavities where such cytotoxic chemicals become in close contact to dental pulp. Therefore, further in vivo studies on animal models are recommended to support or refute these in vitro findings.
    MeSH term(s) Analysis of Variance ; Animals ; Apoptosis/physiology ; Biocompatible Materials ; Dental Cements/pharmacology ; Dentin-Bonding Agents/pharmacology ; Immunoenzyme Techniques ; Mice ; Odontoblasts/drug effects
    Chemical Substances Biocompatible Materials ; Clearfil Protect Bond ; Dental Cements ; Dentin-Bonding Agents ; Xeno III ; Xeno V
    Language English
    Publishing date 2012-06
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80227-x
    ISSN 1879-1506 ; 0003-9969
    ISSN (online) 1879-1506
    ISSN 0003-9969
    DOI 10.1016/j.archoralbio.2011.11.019
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    Ul III Zs.151: Show issues Location:
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  6. Article ; Online: Effect of 16% carbamide peroxide bleaching gel on enamel and dentin surface micromorphology and roughness of uremic patients: an atomic force microscopic study.

    Mahmoud, Salah Hasab / Elembaby, Abeer El Sayed / Zaher, Ahmed Ragheb / Grawish, Mohammed El-Awady / Elsabaa, Heba M / El-Negoly, Salwa Abd El-Raof / Sobh, Mohamed Abdel Kader

    European journal of dentistry

    2010  Volume 4, Issue 2, Page(s) 175–182

    Abstract: Objectives: To investigate the effect of 16% carbamide peroxide bleaching gel on surface micromorphology and roughness of enamel and root dentin of uremic patients receiving hemodialysis using atomic force microscopy (AFM).: Methods: A total of 20 ... ...

    Abstract Objectives: To investigate the effect of 16% carbamide peroxide bleaching gel on surface micromorphology and roughness of enamel and root dentin of uremic patients receiving hemodialysis using atomic force microscopy (AFM).
    Methods: A total of 20 sound molars were collected from healthy individuals (n=10) and uremic patients (n=10). The roots were separated from their crowns at the cemento-enamel junction. Dental slabs (3 mm x 2 mm x 2 mm) were obtained from the buccal surface for enamel slabs and the cervical third of the root surface for dentin slabs. Dental slabs were then flattened and serially polished up to #2500-grit roughness using silicon carbide abrasive papers. Half of the slabs obtained from healthy individuals and uremic patients were stored in artificial saliva and left without bleaching for control and comparison. The remaining half was subjected to a bleaching treatment using 16% carbamide peroxide gel (Polanight, SDI Limited) 8 h/day for 14 days and stored in artificial saliva until AFM analysis was performed. Statistical analysis of the roughness average (Ra) results was performed using one-way ANOVA and Bonferroni post hoc multiple comparisons test.
    Results: The micromorphological observation of bleached, healthy enamel showed exaggerated prism irregularities more than non-bleached specimens, and this observation was less pronounced in bleached uremic enamel specimens with the lowest Ra. Bleached healthy dentin specimens showed protruded peritubular dentin and eroded intertubular dentin with the highest Ra compared to bleached uremic dentin.
    Conclusions: The negative effects of the bleaching gel on uremic tooth substrates are less dramatic and non-destructive compared to healthy substrates because uremia confers different micromorphological surface changes.
    Language English
    Publishing date 2010-02-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2491711-4
    ISSN 1305-7464 ; 1305-7464
    ISSN (online) 1305-7464
    ISSN 1305-7464
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  7. Article: Effect of 16% Carbamide Peroxide Bleaching Gel on Enamel and Dentin Surface Micromorphology and Roughness of Uremic Patients: An Atomic Force Microscopic Study

    Mahmoud, Salah Hasab / Elembaby, Abeer El Sayed / Zaher, Ahmed Ragheb / Grawish, Mohammed El-Awady / Elsabaa, Heba M / El- Negoly, Salwa Abd El-Raof / Sobh, Mohamed Abdel Kader

    European Journal of Dentistry

    2010  Volume 04, Issue 02, Page(s) 175–182

    Abstract: Objectives: To investigate the effect of 16% carbamide peroxide bleaching gel on surface micromorphology and roughness of enamel and root dentin of uremic patients receiving hemodialysis using atomic force microscopy (AFM). Methods: A total of 20 sound ... ...

    Abstract Objectives: To investigate the effect of 16% carbamide peroxide bleaching gel on surface micromorphology and roughness of enamel and root dentin of uremic patients receiving hemodialysis using atomic force microscopy (AFM). Methods: A total of 20 sound molars were collected from healthy individuals (n=10) and uremic patients (n=10). The roots were separated from their crowns at the cemento-enamel junction. Dental slabs (3 mm x 2 mm x 2 mm) were obtained from the buccal surface for enamel slabs and the cervical third of the root surface for dentin slabs. Dental slabs were then flattened and serially polished up to #2500-grit roughness using silicon carbide abrasive papers. Half of the slabs obtained from healthy individuals and uremic patients were stored in artificial saliva and left without bleaching for control and comparison. The remaining half was subjected to a bleaching treatment using 16% carbamide peroxide gel (Polanight, SDI Limited) 8 h/day for 14 days and stored in artificial saliva until AFM analysis was performed. Statistical analysis of the roughness average (Ra) results was performed using one-way ANOVA and Bonferroni post hoc multiple comparisons test. Results: The micromorphological observation of bleached, healthy enamel showed exaggerated prism irregularities more than non-bleached specimens, and this observation was less pronounced in bleached uremic enamel specimens with the lowest Ra. Bleached healthy dentin specimens showed protruded peritubular dentin and eroded intertubular dentin with the highest Ra compared to bleached uremic dentin. Conclusions: The negative effects of the bleaching gel on uremic tooth substrates are less dramatic and non-destructive compared to healthy substrates because uremia confers different micromorphological surface changes. (Eur J Dent 2010;4:175-181)
    Keywords Bleaching ; Atomic force microscopy ; Uremic patients ; Carbamide peroxide ; Chronic renal failure
    Language English
    Publishing date 2010-04-01
    Publisher Thieme Medical and Scientific Publishers Private Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2491711-4
    ISSN 1305-7464 ; 1305-7456 ; 1305-7464
    ISSN (online) 1305-7464
    ISSN 1305-7456 ; 1305-7464
    DOI 10.1055/s-0039-1697827
    Database Thieme publisher's database

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