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Article ; Online: Authors' Reply: Efficacy and Safety of Non-operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-analyses.

Emile, Sameh Hany / Elfeki, Hossam

2022 Volume 46, Issue 8, Page(s) 2010–2011

MeSH term(s)	Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Appendectomy/adverse effects ; Appendicitis/complications ; Appendicitis/surgery ; Humans ; Systematic Reviews as Topic ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-05-30
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-022-06606-w
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Article ; Online: The Authors Reply.

Emile, Sameh Hany / Elfeki, Hossam

Diseases of the colon and rectum

2021 Volume 64, Issue 10, Page(s) e590

Language	English
Publishing date	2021-07-26
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1097/DCR.0000000000002206
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Article ; Online: Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses.

Emile, Sameh Hany / Sakr, Ahmad / Shalaby, Mostafa / Elfeki, Hossam

World journal of surgery

2022 Volume 46, Issue 5, Page(s) 1022–1038

Abstract: Background: Non-operative management (NOM) of uncomplicated acute appendicitis (AA) has been introduced as an alternative to appendectomy. This umbrella review aimed to provide an overview of the efficacy and safety of NOM of uncomplicated AA in the ... ...

Abstract	Background: Non-operative management (NOM) of uncomplicated acute appendicitis (AA) has been introduced as an alternative to appendectomy. This umbrella review aimed to provide an overview of the efficacy and safety of NOM of uncomplicated AA in the published systematic reviews. Methods: This umbrella review has been reported in line with the PRISMA guidelines and umbrella review approach. Systematic reviews with and without meta-analyses on the efficacy of NOM of AA were analyzed. The quality of the reviews was assessed with the AMSTAR 2 tool. The main outcomes measures were the treatment failure and complication rates of NOM and hospital stay as compared to appendectomy. Results: Eighteen systematic reviews were included to this umbrella review. Eight reviews documented higher odds of failure with NOM, whereas two reviews revealed similar odds of failure. Six reviews reported lower odds of complications with NOM, six reported similar odds, and one reported lower odds of complications with surgery. Eight reviews reported similar hospital stay between NOM and appendectomy, one reported longer stay with NOM and another reported shorter stay with NOM. Pooled analyses showed that NOM was associated with higher treatment failure overall, in children-only, adults only, and RCTs-only meta-analyses. NOM was associated with lower complications overall, yet children-only and RCTs-only analyses revealed similar complications to surgery. NOM was associated with shorter stay in the overall and adult-only analysis, but not in the children-only analysis. Conclusions: NOM of AA is associated with higher treatment failure, marginally lower rate of complications and shorter stay than appendectomy.
MeSH term(s)	Acute Disease ; Adult ; Anti-Bacterial Agents/therapeutic use ; Appendectomy/adverse effects ; Appendicitis/drug therapy ; Appendicitis/surgery ; Child ; Humans ; Length of Stay ; Treatment Failure ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-022-06446-8
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Article ; Online: How to treat rectal prolapse in a male patient with faecal incontinence: Delorme's procedure combined with levatorplasty - a video vignette.

Shalaby, Mostafa / Omar, Waleed / Elfeki, Hossam

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2021 Volume 23, Issue 7, Page(s) 1939

MeSH term(s)	Digestive System Surgical Procedures ; Fecal Incontinence/etiology ; Fecal Incontinence/surgery ; Humans ; Male ; Rectal Prolapse/complications ; Rectal Prolapse/surgery ; Rectum/surgery ; Recurrence
Language	English
Publishing date	2021-04-27
Publishing country	England
Document type	Letter ; Video-Audio Media
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15666
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Article ; Online: Plicated Sleeve Gastrectomy with Combined Mesocolon and Greater Omentum Fixation After T-Shaped Omentoplasty: How to Do it?

Abdallah, Emad / Fikry, Mohamed / Rady, Omar / Elfeki, Hossam

Obesity surgery

2020 Volume 30, Issue 3, Page(s) 1173–1174

Abstract: Introduction: This technique aims to evaluate fixation of the sleeved distal part of the stomach to the root of the transverse mesocolon and greater omentum after its shortening in a T-shaped design.: Methods: Sleeve gastrectomy is done in a standard ...

Abstract	Introduction: This technique aims to evaluate fixation of the sleeved distal part of the stomach to the root of the transverse mesocolon and greater omentum after its shortening in a T-shaped design. Methods: Sleeve gastrectomy is done in a standard five-port technique. Then, we fix the distal end of the staple line using an inverting interrupted 2/0 Ticron suture. We plicate the anterior and posterior walls to invert the staple line and then fix it to the mesocolic fat below the pancreas and to the edge of the disconnected distal omentum close to the antrum. Proceeding caudally, we shorten the greater omentum in the form of a T-shaped suture that forms an omental window between the two edges of the omentum. Plication and fixation are continued upwards until the lower border of the pancreas. Then, we plicate the sleeved stomach using a 2/0 Ticron suture starting cranially near the angle of His. Results: All patients are discharged from the hospital the next day and followed-up at the clinic after the end of first and second weeks, then after 3, 6, and 12 months postoperatively. Conclusion: Plicated sleeve gastrectomy combined with mesocolon and greater omentum fixation after T-Shaped omentoplasty is safe and feasible. Long-term follow-up study is required to validate our results.
MeSH term(s)	Follow-Up Studies ; Gastrectomy ; Humans ; Laparoscopy ; Mesocolon/surgery ; Obesity, Morbid/surgery ; Omentum/surgery
Language	English
Publishing date	2020-01-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-019-04382-6
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Article ; Online: Ultrasound-guided versus laparoscopic-guided subcostal transversus abdominis plane (TAP) block versus No TAP block in laparoscopic cholecystectomy; a randomized double-blind controlled trial.

Emile, Sameh Hany / Elfeki, Hossam / Elbahrawy, Khaled / Sakr, Ahmad / Shalaby, Mostafa

International journal of surgery (London, England)

2022 Volume 101, Page(s) 106639

Abstract: Background: Transversus abdominis plane (TAP) block is an effective modality for the control of immediate postoperative pain. The present randomized trial aimed to assess the efficacy of ultrasound-guided subcostal TAP (USTAP) and laparoscopic subcostal ...

Abstract	Background: Transversus abdominis plane (TAP) block is an effective modality for the control of immediate postoperative pain. The present randomized trial aimed to assess the efficacy of ultrasound-guided subcostal TAP (USTAP) and laparoscopic subcostal TAP (LSTAP) block as compared to standard care without TAP block after laparoscopic cholecystectomy. Methods: This was a prospective, randomized, controlled trial on patients who underwent laparoscopic cholecystectomy. Patients were equally randomized to one of three groups: USTAP, LSTAP, and control group (no TAP block). The main outcome measures were pain scores and analgesic consumption within the first 24 h postoperatively, postoperative nausea and vomiting (PONV), time to ambulation, time to first flatus, and adverse effects of TAP block. Results: The trial included 110 patients (90% females) with a mean age of 40.9 ± 11.7 years. Both USTAP and LSTAP block groups were associated with significantly lower pain scores at 2, 6, 12, and 24 h postoperatively, lower cumulative dose of paracetamol, less PONV, and shorter time to flatus than the control group. USTAP and LSTAP block were associated with similar pain scores at all time points, similar analgesic requirements, a similar incidence of PONV, and comparable time to first ambulation and time to first flatus. No adverse effects related to TAP block were recorded. Conclusions: TAP block is a safe and effective method for pain control and improving recovery after laparoscopic cholecystectomy. Both USTAP and LSTAP blocks were equally effective in terms of pain relief, analgesic requirements, PONV, return of bowel function, and time to ambulation.
MeSH term(s)	Abdominal Muscles ; Adult ; Analgesics ; Analgesics, Opioid ; Anesthetics, Local ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystectomy, Laparoscopic/methods ; Double-Blind Method ; Female ; Flatulence/complications ; Humans ; Laparoscopy/adverse effects ; Male ; Middle Aged ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Postoperative Nausea and Vomiting/epidemiology ; Postoperative Nausea and Vomiting/etiology ; Postoperative Nausea and Vomiting/prevention & control ; Prospective Studies ; Ultrasonography, Interventional/methods
Chemical Substances	Analgesics ; Analgesics, Opioid ; Anesthetics, Local
Language	English
Publishing date	2022-04-27
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2212038-5
ISSN	1743-9159 ; 1743-9191
ISSN (online)	1743-9159
ISSN	1743-9191
DOI	10.1016/j.ijsu.2022.106639
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Article: Transvenous Embolization of Brain Arteriovenous Malformations: Up-to-Date Meta-Analysis.

Deniwar, Mohamed Adel / Mustafa, Wessam / Elfeki, Hossam / Eldin, Ashraf Ezz / Awad, Basem I

Turkish neurosurgery

2022 Volume 32, Issue 4, Page(s) 525–534

Abstract: Aim: To conduct an up-to-date meta-analysis to assess the success and complication rates of transvenous embolization (TVE) of brain arteriovenous malformations (BAVMs), and to determine its efficacy and safety.: Material and methods: Relevant and ... ...

Abstract	Aim: To conduct an up-to-date meta-analysis to assess the success and complication rates of transvenous embolization (TVE) of brain arteriovenous malformations (BAVMs), and to determine its efficacy and safety. Material and methods: Relevant and potentially relevant studies from 1982 to February 2021 were searched; after which those that satisfied our eligibility criteria and reported the main outcomes (endovascular occlusion and complication rates) were included. Results: Ultimately seven studies were selected. In total, 154 patients were comprehensively reviewed for BAVMs characteristics and endovascular TVE techniques. The weighted mean rate of immediate endovascular total occlusion, overall technical complication, and overall good functional outcome (mRs < 2) were 93% (95% confidence intervals (CI), 89.1%?96.9%, I2 = 0%, p=0.487), 10.5% (95% CI, 4.3%?16.6%, I2 = 30.8%, p=0.193), and 90.9% (95% CI, 85.3%?96.6%, I2 = 26.6%, p=0.241), respectively. Conclusion: TVE for BAVMs was found to be generally safe and effective in certain selected patients. However, the complementary role of TAE to TVE as a definitive endovascular treatment for BAVMs cannot be separated. More studies regarding this role need to be conducted.
MeSH term(s)	Arteriovenous Malformations/therapy ; Brain ; Central Nervous System Vascular Malformations/therapy ; Embolization, Therapeutic/adverse effects ; Embolization, Therapeutic/methods ; Endovascular Procedures/methods ; Humans ; Intracranial Arteriovenous Malformations/therapy ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2022-05-05
Publishing country	Turkey
Document type	Journal Article ; Meta-Analysis
ZDB-ID	1203779-5
ISSN	1019-5149
ISSN	1019-5149
DOI	10.5137/1019-5149.JTN.36461-21.2
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Article ; Online: Development and Validation of an Artificial Intelligence-Based Model to Predict Gastroesophageal Reflux Disease After Sleeve Gastrectomy.

Emile, Sameh Hany / Ghareeb, Waleed / Elfeki, Hossam / El Sorogy, Mohamed / Fouad, Amgad / Elrefai, Mohamed

Obesity surgery

2022 Volume 32, Issue 8, Page(s) 2537–2547

Abstract: Purpose: Prediction of the onset of de novo gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) would be helpful in decision-making and selection of the optimal bariatric procedure for every patient. The present study aimed to develop ... ...

Abstract	Purpose: Prediction of the onset of de novo gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) would be helpful in decision-making and selection of the optimal bariatric procedure for every patient. The present study aimed to develop an artificial intelligence (AI)-based model to predict the onset of GERD after SG to help clinicians and surgeons in decision-making. Materials and methods: A prospectively maintained database of patients with severe obesity who underwent SG was used for the development of the AI model using all the available data points. The dataset was arbitrarily split into two parts: 70% for training and 30% for testing. Then ranking of the variables was performed in two steps. Different learning algorithms were used, and the best model that showed maximum performance was selected for the further steps of machine learning. A multitask AI platform was used to determine the cutoff points for the top numerical predictors of GERD. Results: In total, 441 patients (76.2% female) of a mean age of 43.7 ± 10 years were included. The ensemble model outperformed the other models. The model achieved an AUC of 0.93 (95%CI 0.88-0.99), sensitivity of 79.2% (95% CI 57.9-92.9%), and specificity of 86.1% (95%CI 70.5-95.3%). The top five ranked predictors were age, weight, preoperative GERD, size of orogastric tube, and distance of first stapler firing from the pylorus. Conclusion: An AI-based model for the prediction of GERD after SG was developed. The model had excellent accuracy, yet a moderate sensitivity and specificity. Further prospective multicenter trials are needed to externally validate the model developed.
MeSH term(s)	Adult ; Artificial Intelligence ; Female ; Gastrectomy/adverse effects ; Gastrectomy/methods ; Gastroesophageal Reflux/diagnosis ; Gastroesophageal Reflux/etiology ; Gastroesophageal Reflux/surgery ; Humans ; Laparoscopy/methods ; Male ; Middle Aged ; Obesity, Morbid/surgery
Language	English
Publishing date	2022-05-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-022-06112-x
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Article ; Online: Long-term bowel dysfunction after right-sided hemicolectomy for cancer.

Larsen, Helene Mathilde / Elfeki, Hossam / Emmertsen, Katrine Jøssing / Laurberg, Søren

Acta oncologica (Stockholm, Sweden)

2020 Volume 59, Issue 10, Page(s) 1240–1245

MeSH term(s)	Colectomy ; Colonic Neoplasms/surgery ; Humans ; Intestine, Large/physiopathology ; Laparoscopy ; Treatment Outcome
Language	English
Publishing date	2020-06-05
Publishing country	England
Document type	Letter
ZDB-ID	896449-x
ISSN	1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
ISSN (online)	1651-226X
ISSN	0349-652X ; 0284-186X ; 1100-1704
DOI	10.1080/0284186X.2020.1772502
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Article ; Online: Urinary dysfunction after colorectal cancer treatment and its impact on quality of life - a national cross-sectional study in women.

Sinimäki, Saija / Elfeki, Hossam / Kristensen, Marianne Højsgaard / Laurberg, Søren / Emmertsen, Katrine J

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2021 Volume 23, Issue 2, Page(s) 384–393

Abstract: Aim: The aim of this study was to investigate urinary dysfunction and its impact on the quality of life of colorectal cancer survivors. We also wanted to identify the risk factors for impaired urinary function.: Method: A national cross-sectional ... ...

Abstract	Aim: The aim of this study was to investigate urinary dysfunction and its impact on the quality of life of colorectal cancer survivors. We also wanted to identify the risk factors for impaired urinary function. Method: A national cross-sectional study was performed including patients treated for colorectal cancer between 2001 and 2014. Patients answered questionnaires regarding urinary function and quality of life, including the International Consultation on Incontinence Questionnaire - Female Lower Urinary Tract Symptoms (ICIQ-FLUTS), measuring filling, voiding and incontinence. Data were compared with data on demographics and treatment-related factors from the Danish Colorectal Cancer Group (DCCG) database. Results: We found that rectal cancer treatment significantly impaired urinary function compared with colon cancer treatment (filling score p = 0.003, voiding p < 0.0001, incontinence p = 0.0001). Radiotherapy was the single most influential risk factor for high filling (p = 0.0043), voiding (p < 0.0001) and incontinence (p < 0.0001) scores, whereas type of rectal resection was only significant in crude analysis. Urinary dysfunction was strongly associated with an impaired quality of life. Conclusion: Urinary dysfunction is common after treatment for colorectal cancer, particularly if the treatment includes radiotherapy. All patients must be informed of the risk before cancer treatment, and functional outcome should be routinely assessed at follow-up.
MeSH term(s)	Cross-Sectional Studies ; Female ; Humans ; Quality of Life ; Rectal Neoplasms ; Surveys and Questionnaires ; Urinary Incontinence/epidemiology ; Urinary Incontinence/etiology
Language	English
Publishing date	2021-02-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15541
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