Article ; Online: Synthesis, computational chemical study, antiproliferative activity screening, and molecular docking of some thiophene-based oxadiazole, triazole, and thiazolidinone derivatives.
RSC advances
2024 Volume 14, Issue 9, Page(s) 5926–5940
Abstract: Thiophene-2-carbohydrazide was used in this study to produce some thiophene-containing oxadiazole, triazole, and thiazolidinone derivatives through reactions with various carbon-centered electrophiles. Besides, the hydrazone obtained was allowed to react ...
| Abstract | Thiophene-2-carbohydrazide was used in this study to produce some thiophene-containing oxadiazole, triazole, and thiazolidinone derivatives through reactions with various carbon-centered electrophiles. Besides, the hydrazone obtained was allowed to react with mercaptoacetic acid and acetic anhydride to construct thiazolidinone and oxadiazole derivatives. The results of computational chemical study and outcomes of the experiments were in good agreement. The |
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| Language | English |
| Publishing date | 2024-02-15 |
| Publishing country | England |
| Document type | Journal Article |
| ISSN | 2046-2069 |
| ISSN (online) | 2046-2069 |
| DOI | 10.1039/d3ra07048d |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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