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  1. Article ; Online: White blood cell count and clustered components of metabolic syndrome

    Mohammad Taghi Hedayati / Mahdi Montazeri / Negin Rashidi / Elham Yousefi abdolmaleki / Mohammad-Ali Shafiee / Ali Maleki / Maryam Farmani / Mohammad Montazeri

    Caspian Journal of Internal Medicine, Vol 12, Iss 1, Pp 59-

    A study in western Iran

    2021  Volume 64

    Abstract: Background: White blood cell count (WBC) is one of the objective parameters of systemic inflammation. The aim of present study was to evaluate the relationship between WBC count and metabolic syndrome. Methods: In this study on Lor population in Borujerd ...

    Abstract Background: White blood cell count (WBC) is one of the objective parameters of systemic inflammation. The aim of present study was to evaluate the relationship between WBC count and metabolic syndrome. Methods: In this study on Lor population in Borujerd province (West of Iran), from 2011 to 2013, 800 persons were enrolled. MetS was defined based on ATP III criteria. Differences among the quartiles of WBC were examined by one-way analysis of variance. Results: Only 14.7% did not have any of the five components and 43% of all subjects had metabolic syndrome. The means of WBC count in MetS group were significantly higher than the control group (p<0.0001). In subjects without any MetS components, the means of WBC was 5.321 /µL, and it was 5.664, 5.714, 5.961, 6.302, and 6.572 /µL in subjects with 1, 2, 3, 4, and 5 components, respectively. These differences show a significant increasing trend (p<0.0001). Conclusion: WBC count was associated with clustered components of metabolic syndrome. It seems that WBC counts could be considered as a predictive factor for metabolic syndrome in preventive medicine.a
    Keywords metabolic syndrome ; white blood cell ; inflammation ; Internal medicine ; RC31-1245
    Subject code 630
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Babol University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The Impact of Fasting on Metabolic and Anthropometric Parameters in Type II Diabetic Patients

    Tayebeh Yazdanyar / Mehrnoush Sohrab / Atena Ramezani / Parastoo Karimi Aliabadi / Adele Bahar / Mahboobeh Shirzad / Elham Yousefi Abdolmaleki / Mohsen Aarabi

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 12, Pp OC18-OC

    A Prospective Observational Study

    2020  Volume 23

    Abstract: Introduction: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is therefore, necessary for patients to receive proper instructions about their physical activities, eating habits, blood glucose monitoring and ...

    Abstract Introduction: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is therefore, necessary for patients to receive proper instructions about their physical activities, eating habits, blood glucose monitoring and medications. Aim: To investigate the effects of fasting on metabolic and anthropometric indices in type II diabetic patients. Materials and Methods: This prospective observational study was performed during Ramadan 2018. The study population consisted of 40 type II diabetic patients (33 females and 7 males) who wished to fast. They started to follow given instructions on their physical activity, eating habits, blood glucose monitoring, and medications before Ramadan. Anthropometric variables were measured pre and post-Ramadan. Fasting Blood/Plasma Glucose (FBG/FPG), Glucose 2 Hour Postprandial (2h PPG), glycosylated haemoglobin (HbA1c), and the lipids profile were assessed before and after Ramadan. FPG and 2h PPG were also evaluated on the fifteenth day of Ramadan. Data were presented as mean±SD. Paired t-test was employed and a p-value of <0.05 was considered statistically significant. Results: After completion of the study, anthropometric variables of patients, including weight (74.9±12.7 vs. 73.0±13.1 kg, p<0.001), BMI (29.9±5.2 vs. 29.0±5.1 kg/m2 , p=0.042), waist circumference (106.2±11.8 vs. 105.3±11.6 cm, p<0.001), conicity index (9.94±0.96 vs 9.80±0.99, p=0.085), systolic blood pressure (118.5±10.6 vs. 113.8±9.4 mmHg, p=0.018), Diastolic blood pressure (72.0±7.9 vs. 68.3±7.0 mmHg, p=0.02) and FPG (125.1±27.4 vs. 105.2±21.4 mg/dL, p<0.001) decreased significantly. However, serum triglyceride increased significantly (127.5±45.5 vs. 166.5±53.5 mg/dL, p<0.001) after fasting compared to pre-Ramadan measurements. Changes in other variables were not statistically significant. Conclusion: The results of this study indicate that fasting had beneficial effect on fasting blood glucose level and anthropometric parameters in type II diabetic patients.
    Keywords blood glucose ; body mass index ; cholesterol low density lipoprotein ; conicity index ; family physician ; high density lipoprotein cholesterol ; waist to hip ratio ; Medicine ; R
    Subject code 796 ; 610
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The rabies early death phenomenon

    Mahmoud Sadeghi / Shams-ali Hadizadeh Moallem / Elham Yousefi-Abdolmaleki / Mohammad Montazeri

    Indian Journal of Critical Care Medicine, Vol 19, Iss 7, Pp 422-

    A report of ineffective administration of rabies vaccine during symptomatic disease

    2015  Volume 424

    Abstract: It was reported that in some individuals who received postexposure rabies vaccine, clinical features of rabies developed at the shorter time compared to individuals who were exposed, but not received the vaccine, which called "early death" phenomenon. We ...

    Abstract It was reported that in some individuals who received postexposure rabies vaccine, clinical features of rabies developed at the shorter time compared to individuals who were exposed, but not received the vaccine, which called "early death" phenomenon. We reported an early death phenomenon in a 67-year-old woman who was bitten by a jackal, although receiving three dose of rabies vaccine. Results show that the immune response to rabies has a dual role, sometimes has a favorable effect on survival but sometimes amplification the disease.
    Keywords Early death ; postexposure vaccine ; rabies ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Metabolic syndrome and its components associated with chronic kidney disease

    Ali Maleki / Mahdi Montazeri / Negin Rashidi / Mohammad Montazeri / Elham Yousefi-Abdolmaleki

    Journal of Research in Medical Sciences, Vol 20, Iss 5, Pp 465-

    2015  Volume 469

    Abstract: Background: There is limited information on the relationship between metabolic syndrome (MetS) and chronic kidney disease (CKD) in the Iranian population, a group that has a high prevalence of CKD and obesity. The aim of present study was to determine ... ...

    Abstract Background: There is limited information on the relationship between metabolic syndrome (MetS) and chronic kidney disease (CKD) in the Iranian population, a group that has a high prevalence of CKD and obesity. The aim of present study was to determine the relationship between MetS and CKD in West of Iran. Materials and Methods: A total of 800 subjects aged more than 35 years admitted from 2011 to 2013 were enrolled in the study. MetS was defined based on the Adult Treatment Panel III criteria, and CKD was defined from the Kidney Disease Outcomes Quality Initiative practice guidelines. Waist circumference and body mass index were calculated, as well, blood samples were taken and lipid profile, plasma glucose levels, and serum creatinine were measured. Data were analyzed with SPSS version 17 (SPSS Inc., Chicago, IL, USA). Results: CKD was seen in 14.8% patients with MetS and 8.3% individuals without MetS. MetS was associated with an increased odds ratio (OR) for a glomerular filtration rate <60 ml/min/1.73 m 2 (OR: 1.91; 95% confidence interval [CI]: 1.22-2.99; P = 0.004). Individuals with 2, 3, 4, and 5 components of the MetS had an increased OR for CKD: 2.19 (95% CI: 0.95-3.62), 2.65 (95% CI: 1.03-4.71), 2.86 (95% CI: 1.08-5.53), and 5.03 (95% CI: 1.80-8.57), respectively, compared with individuals with none of the components. Conclusion: We found a high prevalence of CKD in patients with MetS compared with the subject without MetS. Our observations raised major clinical and public health concerns in Iran, where both the MetS and kidney diseases are becoming common.
    Keywords Chronic kidney disease ; end-stage renal disease ; metabolic syndrome ; serum creatinine ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The Effect of 8 Weeks Aerobic Exercise on Insulin Resistance in Type 2 Diabetes

    Narges Motahari-Tabari / Marjan Ahmad Shirvani / Mahbobeh Shirzad-e-Ahoodashty / Elham Yousefi-Abdolmaleki / Mojgan Teimourzadeh

    Global Journal of Health Science, Vol 7, Iss

    A Randomized Clinical Trial

    2014  Volume 1

    Abstract: Diabetes complications are the main reasons behind morbidity and mortality preventable by healthy diet and physical activity. There are few studies about the effect of aerobic exercises on insulin resistance in human. Also various training protocols are ... ...

    Abstract Diabetes complications are the main reasons behind morbidity and mortality preventable by healthy diet and physical activity. There are few studies about the effect of aerobic exercises on insulin resistance in human. Also various training protocols are associated with different results. Since approaches to decrease insulin resistance may be followed by more effectiveness treatment, this study assessed the effect of aerobic exercise on insulin resistance in type 2 diabetes mellitus. In this randomized clinical trial, 53 type 2 diabetic women were randomly divided into two groups as exercise (n=27) and control (n=26).The exercise protocol included warm-up by stretching and flexibility exercises for 10 m, followed by walking for 30 m with maximum intensity 60% increase in heart rate and then stretching in the seated position for 10 m, 3 times a week for 8 weeks. Resistance to insulin was assessed using Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Significant differences have been observed in insulin resistance, fasting glucose and plasma insulin between the groups after 8 weeks. There were significant differences in waist and hip circumference, BMI, plasma insulin and insulin resistance within the groups over time. In addition, the changes in waist and hip circumference, FBS, plasma insulin and insulin resistance had significant interaction with the time between the groups. The current exercise protocol has been effective in lowering plasma glucose (p = 0.05), insulin levels (p = 0.000) and insulin resistance (p = 0.02). It seems that aerobic exercises training promote the effectiveness of medical treatment in type 2diabetes mellitus.
    Keywords Medicine (General) ; R5-920 ; Medicine ; R
    Subject code 571
    Language English
    Publishing date 2014-07-01T00:00:00Z
    Publisher Canadian Center of Science and Education
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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