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  1. Article ; Online: Olanzapine induced hyponatremia and rhabdomyolysis

    N'joumi Younes / Haimeur Yassine / El Harfaoui Yassine / Benhlima Abdelkader / Elhamzaoui Hamza / Alilou Mustapha

    Clinical Case Reports, Vol 11, Iss 2, Pp n/a-n/a (2023)

    2023  

    Abstract: Abstract Rapid‐onset hyponatremia and rhabdomyolysis are rare, but potential, complications of olanzapine treatment. Hyponatremia, secondary to atypical antipsychotic use, has been reported in many case reports and is thought to be associated with an ... ...

    Abstract Abstract Rapid‐onset hyponatremia and rhabdomyolysis are rare, but potential, complications of olanzapine treatment. Hyponatremia, secondary to atypical antipsychotic use, has been reported in many case reports and is thought to be associated with an inappropriate antidiuretic hormone secretion syndrome. We report a case of sudden‐onset hyponatremia associated with a severe rhabdomyolysis resulting in a coma‐necessitating intensive care unit admission. His evolution was favorable after correction of all his metabolic disorders and olanzapine suspension.
    Keywords hyponatremia ; olanzapine ; rhabdomyolysis ; side effects ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Coronavirus disease 2019 (COVID-19) pathogenesis: a concise narrative review.

    Elhamzaoui, Hamza / Rebahi, Houssam / Hachimi, Abdelhamid

    The Pan African medical journal

    2021  Volume 39, Page(s) 8

    Abstract: SARS-CoV-2 is the third zoonotic coronavirus. Since December 2019, it has spread through the globe and infects more than four million patients (as of May ... ...

    Abstract SARS-CoV-2 is the third zoonotic coronavirus. Since December 2019, it has spread through the globe and infects more than four million patients (as of May 10
    MeSH term(s) Animals ; COVID-19/complications ; COVID-19/epidemiology ; COVID-19/physiopathology ; Global Health ; Humans ; SARS-CoV-2/isolation & purification ; Viral Zoonoses/complications ; Viral Zoonoses/epidemiology ; Viral Zoonoses/physiopathology
    Language English
    Publishing date 2021-05-03
    Publishing country Uganda
    Document type Journal Article ; Review
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2021.39.8.23546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Post-vaccine COVID-19 acute myocarditis: case reports and literature review.

    Bouchaala, Abderrahmane / Nguadi, Jaouad / Benhlima, Abdelakder / Arfaoui, Manal / Elhamzaoui, Hamza / Alilou, Mustapha

    The Pan African medical journal

    2023  Volume 44, Page(s) 192

    Abstract: COVID-19 vaccines have reduced both lethality and hospitalization rates of the novel coronavirus disease. Nevertheless, multiple side effects have been reported in the literature, most often are harmless. We report two cases of acute myocarditis, ... ...

    Abstract COVID-19 vaccines have reduced both lethality and hospitalization rates of the novel coronavirus disease. Nevertheless, multiple side effects have been reported in the literature, most often are harmless. We report two cases of acute myocarditis, hospitalized in the emergency department for chest pain occurring after the second dose of mRNA vaccine AstraZeneca. The SARS-Cov-2 infection was ruled out in both patients with a negative PCR obtained by nasal swabs and normal thoracic CT scans. Both patients had high levels of high-sensitive cardiac troponin I. Acute coronary syndromes were excluded with cardiac catheterization. Cardiac Magnetic resonance imaging (MRI) showed signs in favor of acute myocarditis. The evolution was favorable for both patients after being put on anti-inflammatory treatment. The universality and accumulation of reports concerning acute myocarditis following COVID vaccination, in the absence of any other diagnostic element that could explain the myocardial injury, establish a strong causal link, although the etiopathogenesis of such injury remains poorly elucidated.
    MeSH term(s) Humans ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Myocarditis/diagnosis ; Myocarditis/etiology ; SARS-CoV-2 ; Vaccination ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-04-20
    Publishing country Uganda
    Document type Review ; Case Reports
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2023.44.192.35425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Compliance With World Health Organization (WHO)-World Federation of Societies of Anesthesiologists (WFAS) Standards for General Anesthesia at Ibn Sina University Hospital Center, Morocco.

    Harfaoui, Wafaa / Ziani, Hicham / Slaihi, Zakaria / Arfaoui, Manal / Armel, Bouchra / Elhamzaoui, Hamza / Belyamani, Lahcen / Alilou, Mustapha / Obtel, Majdouline

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51980

    Abstract: Introduction: Patient safety in anaesthesia has significantly improved over the past decades, largely due to pharmacological and technological advancements, as well as the widespread adoption of guidelines and standards recommended by international ... ...

    Abstract Introduction: Patient safety in anaesthesia has significantly improved over the past decades, largely due to pharmacological and technological advancements, as well as the widespread adoption of guidelines and standards recommended by international organisations. This study aimed to evaluate the practice of anaesthesia and its compliance with the international standards for safe anaesthesia practice recommended by the World Federation of Societies of Anaesthesiologists (WFSA) and the World Health Organization (WHO). This study also describes the operating room within Ibn Sina University Hospital Centre (CHUIS) of Rabat, Morocco, the referral centre, with the aim of identifying its potential and shortcomings.
    Methods: This was a prospective analytical descriptive study from March 1, 2021, to July 31, 2021. All facilities within an operating room and information regarding patients undergoing general anaesthesia, whether it be emergency or scheduled procedures, administered by an anaesthetist, were included. A survey form based on the WHO-WFSA International Standards for a Safe Practice of Anesthesia was used to collect data about the anaesthesia sites. Sources of information included direct observation of anaesthesia procedures, patient records, registers, and qualified anaesthesia personnel. Manual data analysis and encoding were performed using Microsoft Word and Excel (Microsoft Corporation, Redmond, Washington, United States).  Results: All the facilities within the operating rooms of CHUIS were surveyed. In total, 250 patients were recorded, with 43.6% at Ibn Sina Hospital, 18.4% in the Children's Hospital, 14% at the National Institute of Oncology, 12% at the Specialties, 6% at Maternity Hospital Souissi, and 6% at Orangers Maternity Hospital. The median age of patients was 50 years old with 37% of them aged 36-55 years. Overall, 67.6% of these patients were admitted for scheduled interventions. Anaesthetic risk assessment showed that 67.2% of the patients were in American Society of Anesthesiologists (ASA) class I. Pre-anaesthesia consultations were conducted in 65.6% of cases, and pre-anaesthesia visits were conducted in 89.6% of cases. Anaesthesia checklists were used in 89.6% of cases. General anaesthesia, including tracheal intubation 85.2% and facemask 7.2%, was the most common type of anaesthesia. Regarding anaesthetic agents, propofol was the most used intravenous narcotic, with fentanyl still being used in most cases 92% and rocuronium in 82% of cases. Electrocardiogram, non-invasive blood pressure, and pulse oxygen saturation (SPO2) monitoring were consistently used, while capnography was not available in 6% of cases. Crystalloid fluid resuscitation was used in 91.2% of cases, and colloid resuscitation was used in 1.2% of cases. The post-anesthesia care unit (PACU) was present in 58.8% of cases. Postoperative analgesia was administered in 80% of cases. Adverse events occurred in 58.4% of cases. Preoperative transfusion strategies were employed in 18% of cases. Patient transfers to the intensive care unit were done for 18%.
    Conclusion: Despite the shortcomings of the healthcare system in Morocco, our study indicates that the anaesthesia practice at CHUIS remains highly acceptable by adhering to the highest international standards.
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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