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  1. Article ; Online: The amazing shift.

    Elledge, Carole M

    Journal for nurses in professional development

    2014  Volume 30, Issue 5, Page(s) E1–2

    Abstract: Some learn by hearing. Some learn by seeing. We all learn by doing. In an effort to creatively integrate skills evaluation and critical thinking in our new nurses, we developed an educational offering entitled "The Amazing Shift." In this activity, small ...

    Abstract Some learn by hearing. Some learn by seeing. We all learn by doing. In an effort to creatively integrate skills evaluation and critical thinking in our new nurses, we developed an educational offering entitled "The Amazing Shift." In this activity, small teams of graduate nurses in our medical-surgical residency are tasked with managing simulated patient scenarios within specific time constraints, similar to managing a multipatient assignment on their unit. This "low-tech" approach has consistently been selected as one of the most meaningful classroom-based activities by the participants.
    MeSH term(s) Clinical Competence ; Education, Nursing ; Humans ; Inservice Training ; Internship, Nonmedical ; Manikins ; Work Performance
    Language English
    Publishing date 2014-09
    Publishing country United States
    Document type Journal Article
    ISSN 2169-981X
    ISSN (online) 2169-981X
    DOI 10.1097/NND.0000000000000104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Early antimicrobial prophylaxis in autologous stem cell transplant recipients: Conventional versus an absolute neutrophil count-driven approach.

    Horowitz, Justin G / Gawrys, Gerard W / Lee, Grace C / Ramirez, Brittney A / Elledge, Carole M / Shaughnessy, Paul J

    Transplant infectious disease : an official journal of the Transplantation Society

    2021  Volume 23, Issue 4, Page(s) e13689

    Abstract: Background: Autologous hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of developing life-threatening infections. There is discordance in published recommendations for timing of pre- and post-transplant antimicrobial ... ...

    Abstract Background: Autologous hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of developing life-threatening infections. There is discordance in published recommendations for timing of pre- and post-transplant antimicrobial prophylaxis in this patient population, and these recommendations are unsubstantiated by any published comparative analyses.
    Methods: An observational, pre- and post-intervention study of consecutive autologous HSCT recipients was conducted over a 2-year period. In the pre-intervention cohort, antimicrobial prophylaxis was initiated on the day prior to transplant. In the post-intervention cohort, antimicrobials were initiated once absolute neutrophil count (ANC) reached ≤500 cells/mm
    Results: A total of 208 patients were included in the final analysis, with 105 and 103 patients in the pre- and post-intervention cohorts, respectively. The majority of patients included were male. Lower rates of fever occurrences were observed in the post-intervention cohort (83% pre- vs. 69% post-intervention; p = 0.019). A significant reduction in the mean antibacterial days per patient was identified (9.7 vs. 4.6 days; p < 0.001). Other than lower rates of febrile neutropenia in the post-intervention cohort, no differences were identified in secondary outcomes. In multivariable analyses, ANC-driven prophylaxis was independently associated with decreased febrile events.
    Conclusions: Delaying prophylaxis until severe neutropenia was not associated with increased febrile events or other secondary clinical outcomes evaluated. This approach is associated with a significant reduction in antimicrobial exposure.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; Female ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Male ; Neutrophils ; Retrospective Studies ; Transplant Recipients
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2021-07-30
    Publishing country Denmark
    Document type Journal Article ; Observational Study
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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