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  1. Article ; Online: Granulomatous Hepatitis Following Intra-Vesical Instillation of Bacillus Calmette–Guérin for Treatment of Bladder Cancer

    Elsa Alves Branco / Raquel Duro / Teresa Brito / António Sarmento

    Infectious Disease Reports, Vol 13, Iss 57, Pp 611-

    2021  Volume 618

    Abstract: Intra-vesical instillation of bacillus Calmette–Guérin (BCG) is an important treatment modality of superficial bladder cancer. It is usually well tolerated, although some adverse reactions can occur. One possible yet rare complication is granulomatous ... ...

    Abstract Intra-vesical instillation of bacillus Calmette–Guérin (BCG) is an important treatment modality of superficial bladder cancer. It is usually well tolerated, although some adverse reactions can occur. One possible yet rare complication is granulomatous hepatitis, that is thought to be caused either by BCG infection or a hypersensitivity reaction to the bacillus. We present a case of a 79-year-old apparently immunocompetent patient who developed granulomatous hepatitis a few months after BCG administration for bladder cancer immunotherapy. It is important to notice that acid-fast smears and cultures are often negative, and these should not exclude diagnosis nor delay treatment. Our case highlights the importance of clinical suspicion and prompt initiation of appropriate treatment.
    Keywords granulomatous hepatitis ; bacillus Calmette–Guérin ; bladder cancer ; Other systems of medicine ; RZ201-999
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: How Supportive Ethical Relationships Are Negatively Related to Palliative Care Professionals’ Negative Affectivity and Moral Distress

    Francisca Rego / Valentina Sommovigo / Ilaria Setti / Anna Giardini / Elsa Alves / Julliana Morgado / Marina Maffoni

    International Journal of Environmental Research and Public Health, Vol 19, Iss 3863, p

    A Portuguese Sample

    2022  Volume 3863

    Abstract: In the modern healthcare landscape, moral distress has become an increasingly common phenomenon among healthcare professionals. This condition is particularly prevalent among palliative care professionals who are confronted with bioethical issues in ... ...

    Abstract In the modern healthcare landscape, moral distress has become an increasingly common phenomenon among healthcare professionals. This condition is particularly prevalent among palliative care professionals who are confronted with bioethical issues in their daily practice. Although some studies described the effects of poor ethical climate and negative affectivity on moral distress, how these variables could be incorporated into a single model is still unclear. Thus, this study aims to investigate whether ethical relationships with the hospital could be related to the intensity and frequency of moral distress, both directly and as mediated by professionals’ negative affectivity. Sixty-one Portuguese palliative care professionals completed web-based self-report questionnaires. After exploring descriptive statistics, mediation analyses were performed using the partial least squares method. The results indicated that the presence of positive relationships with the hospital reduced the professionals’ negative affectivity levels. This, in turn, led palliative care professionals to experience a lower frequency and intensity of moral distress. Being a physician was positively associated with negative affectivity but not with the frequency of moral distress. Considering the protective role of ethical relationships with hospitals, health organizations could consider implementing interventions to improve hospitals’ ethical climate and provide staff with ethics training programs.
    Keywords moral distress ; ethical climate ; negative affectivity ; healthcare professionals ; Medicine ; R
    Subject code 170
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Granulomatous Hepatitis Following Intra-Vesical Instillation of Bacillus Calmette-Guérin for Treatment of Bladder Cancer.

    Branco, Elsa Alves / Duro, Raquel / Brito, Teresa / Sarmento, António

    Infectious disease reports

    2021  Volume 13, Issue 3, Page(s) 611–618

    Abstract: Intra-vesical instillation of bacillus Calmette-Guérin (BCG) is an important treatment modality of superficial bladder cancer. It is usually well tolerated, although some adverse reactions can occur. One possible yet rare complication is granulomatous ... ...

    Abstract Intra-vesical instillation of bacillus Calmette-Guérin (BCG) is an important treatment modality of superficial bladder cancer. It is usually well tolerated, although some adverse reactions can occur. One possible yet rare complication is granulomatous hepatitis, that is thought to be caused either by BCG infection or a hypersensitivity reaction to the bacillus. We present a case of a 79-year-old apparently immunocompetent patient who developed granulomatous hepatitis a few months after BCG administration for bladder cancer immunotherapy. It is important to notice that acid-fast smears and cultures are often negative, and these should not exclude diagnosis nor delay treatment. Our case highlights the importance of clinical suspicion and prompt initiation of appropriate treatment.
    Language English
    Publishing date 2021-07-01
    Publishing country Switzerland
    Document type Case Reports
    ISSN 2036-7430
    ISSN 2036-7430
    DOI 10.3390/idr13030057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  4. Article ; Online: Treatment failure after multiple courses of triclabendazole in a Portuguese patient with fascioliasis.

    Branco, Elsa Alves / Ruas, Rogerio / Nuak, João / Sarmento, António

    BMJ case reports

    2020  Volume 13, Issue 3

    Abstract: Fascioliasis is a trematode flatworm infection caused ... ...

    Abstract Fascioliasis is a trematode flatworm infection caused by
    MeSH term(s) Adult ; Animals ; Antiplatyhelmintic Agents/therapeutic use ; Fascioliasis/drug therapy ; Female ; Humans ; Portugal ; Treatment Failure ; Triclabendazole/therapeutic use
    Chemical Substances Antiplatyhelmintic Agents ; Triclabendazole (4784C8E03O)
    Language English
    Publishing date 2020-03-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-232299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Eczema herpeticum.

    Branco, Elsa Alves / Ribeiro, Lúcia / Ribeiro, Margarida / Martins, António / Policarpo, Sílvia / Enes, João / Silva, José Miguel Lessa / Santos, André / Sarmento, António / Ceia, Filipa

    IDCases

    2021  Volume 26, Page(s) e01299

    Language English
    Publishing date 2021-10-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2021.e01299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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