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  1. Article ; Online: Categorization of Functional Constipation in Traditional Persian Medicine: A Descriptive Study.

    Elsagh, Mahin / Behbahani, Farshad Amini / Fartookzadeh, Mohammad Reza / Adibi, Peyman / Kamalinejad, Mohammad / Anushiravani, Majid

    Journal of evidence-based complementary & alternative medicine

    2016  Volume 21, Issue 1, Page(s) 48–52

    Abstract: Functional constipation (FC) is a common clinical condition without any specific physiological causes with economic cost and adverse effects on patients' quality of life. The present study aimed to evaluate the causes of nonobstructive constipation in ... ...

    Abstract Functional constipation (FC) is a common clinical condition without any specific physiological causes with economic cost and adverse effects on patients' quality of life. The present study aimed to evaluate the causes of nonobstructive constipation in traditional Persian medicine and its prevalence in patients with functional constipation by content analysis of patients' interviews and clinical exams. In this study, almost two thirds of the patients with functional constipation had mild to severe cold distemperament of the gastrointestinal system, and in almost half of them the signs and symptoms were compatible with dry distemperament of the gastrointestinal. This observational study reports high prevalence of gastrointestinal system distemperaments in patients with functional constipation. According to the results, we can consider the proposed management of distemperaments in traditional Persian medicine for functional constipation treatment and pathophysiology explanation. This project is a novel study that provides the opportunity for investigating the epidemiological aspects of these distemperaments and their relationship with functional constipation.
    MeSH term(s) Adolescent ; Adult ; Aged ; Cohort Studies ; Constipation/classification ; Constipation/diagnosis ; Constipation/epidemiology ; Constipation/physiopathology ; Female ; Humans ; Iran ; Male ; Medicine, Traditional/methods ; Middle Aged ; Quality of Life ; Temperament/classification ; Young Adult
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2604898-X
    ISSN 2156-5899 ; 2156-5872
    ISSN (online) 2156-5899
    ISSN 2156-5872
    DOI 10.1177/2156587215594745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Basic Temperament among Patients with Functional Constipation.

    Elsagh, Mahin / Fartookzadeh, Mohammadreza / Adibi, Peyman / Amini Behbahani, Farshad / Kamalinejad, Mohammad

    Iranian journal of public health

    2015  Volume 44, Issue 10, Page(s) 1438–1439

    Language English
    Publishing date 2015-10
    Publishing country Iran
    Document type Journal Article
    ISSN 2251-6085
    ISSN 2251-6085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy of the Malva sylvestris L. flowers aqueous extract for functional constipation: A placebo-controlled trial.

    Elsagh, Mahin / Fartookzadeh, Mohammad Reza / Kamalinejad, Mohammad / Anushiravani, Majid / Feizi, Awat / Behbahani, Farshad Amini / Rafiei, Rahmatollah / Arjmandpour, Akbar / Adibi, Peyman

    Complementary therapies in clinical practice

    2015  Volume 21, Issue 2, Page(s) 105–111

    Abstract: Objective: To evaluate the efficacy of Malva sylvestris L. flowers extract for treatment of FC.: Method: Adults with FC were allocated to receive the M. sylvestris L. flowers aqueous extract syrup (MSL, 1 g extract/day) or placebo for four weeks. ... ...

    Abstract Objective: To evaluate the efficacy of Malva sylvestris L. flowers extract for treatment of FC.
    Method: Adults with FC were allocated to receive the M. sylvestris L. flowers aqueous extract syrup (MSL, 1 g extract/day) or placebo for four weeks. Frequency of constipation symptoms and stool forms were assessed every week. Self-reported improvement was assessed after treatment.
    Results: Compared with placebo, more increase was observed in defecation frequency (F = 18.8, P < 0.001) and more decrease was observed in frequency of all constipation symptoms by MSL (F = 16.5 to 25.3, all P values <0.001). Also, the MSL group experienced more reduction in frequency of hard stool forms (45.4% vs. 9.1%, P < 0.001) and reported more improvement in all symptoms (all P values <0.01) than placebo.
    Conclusion: The M. sylvestris L. flowers aqueous extract is efficacious and safe for the treatment of FC in adult patients. Investigating the mechanisms of action is warranted. IRCT2014031617032N1.
    MeSH term(s) Adult ; Constipation/drug therapy ; Defecation/drug effects ; Female ; Flowers/chemistry ; Humans ; Male ; Malva/chemistry ; Middle Aged ; Placebos ; Plant Extracts/therapeutic use
    Chemical Substances Placebos ; Plant Extracts
    Language English
    Publishing date 2015-05
    Publishing country England
    Document type Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2182834-9
    ISSN 1873-6947 ; 1744-3881
    ISSN (online) 1873-6947
    ISSN 1744-3881
    DOI 10.1016/j.ctcp.2015.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Efficacy of Persian medicine herbal formulations (capsules and decoction) compared to standard care in patients with COVID-19, a multicenter open-labeled, randomized, controlled clinical trial.

    Karimi, Mehrdad / Zarei, Azadeh / Soleymani, Samaneh / Jamalimoghadamsiahkali, Saeidreza / Asadi, Asmaa / Shati, Mohsen / Jafari, Mohieddin / Rezadoost, Hassan / Kordafshar, Gholamreza / Naghizadeh, Ayeh / Mardi, Raefeh / Namiranian, Parva / Khamechi, Seyed Peyman / Ansari, Narges / Adel Mehraban, Mohammad Sadegh / Aliakbarzadeh, Hananeh / Khanavi, Mahnaz / Esmaealzadeh, Niusha / Moravveji, Alireza /
    Salahi, Mehrdad / Khoi, Maryam / Razzaghi, Reza / Banafshe, Hamid Reza / Alizadeh, Mostafa / Akhbari, Marzieh / Atharizadeh, Mina / Izadikhah, Akram / Elsagh, Mahin / Hossein Zade Ghahnavieh, Mahdi / Eghbalian, Fatemeh / Vanai, Azam / Izadi, Hossein / Moravej, Seyed Ali Al-Hadi / Jazayeri, Seyede Ferdos / Bayat, Houman / Emadi Koochak, Hamid / Zargaran, Arman

    Phytotherapy research : PTR

    2021  Volume 35, Issue 11, Page(s) 6295–6309

    Abstract: Persian medicine has recommended clinical experiences and proper herbal remedies for prevention and treatment of microbial infections and respiratory diseases. An open-label, randomized, controlled, multicenter trial was conducted at five hospitals in ... ...

    Abstract Persian medicine has recommended clinical experiences and proper herbal remedies for prevention and treatment of microbial infections and respiratory diseases. An open-label, randomized, controlled, multicenter trial was conducted at five hospitals in Tehran and Isfahan provinces of Iran on 358 hospitalized adult patients. A total of 174 patients received standard care and 184 received herbal remedies (polyherbal decoction every 8 hr and two herbal capsules every 12 hr) plus standard care for 7 days. The primary clinical endpoint was the duration of hospital stay, and secondary outcomes were clinical improvement of symptoms based on self-assessment questionnaire. Results demonstrated that these natural decoction and capsules treatment plus routine care significantly decreased duration of hospital dyspnea (3.291 day vs. 6.468 days), accelerated clinical improvement, and decreased symptoms such as dry cough, dyspnea, muscle pain, headache, fatigue, anorexia, chills, runny nose, sputum cough, and vertigo in the treatment group compared with standard-care group. Significant effects of these polyherbal formulations on improving the symptoms of COVID-19 could be incredibly promising for managing this pandemic with acceptable tolerability.
    MeSH term(s) Adult ; COVID-19 ; Capsules ; Humans ; Iran ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Capsules
    Language English
    Publishing date 2021-10-04
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.7277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Efficacy of Persian medicine herbal formulations (capsules and decoction) compared to standard care in patients with COVID‐19, a multicenter open‐labeled, randomized, controlled clinical trial

    Karimi, Mehrdad / Zarei, Azadeh / Soleymani, Samaneh / Jamalimoghadamsiahkali, Saeidreza / Asadi, Asmaa / Shati, Mohsen / Jafari, Mohieddin / Rezadoost, Hassan / Kordafshar, Gholamreza / Naghizadeh, Ayeh / Mardi, Raefeh / Namiranian, Parva / Khamechi, Seyed Peyman / Ansari, Narges / Adel Mehraban, Mohammad Sadegh / Aliakbarzadeh, Hananeh / Khanavi, Mahnaz / Esmaealzadeh, Niusha / Moravveji, Alireza /
    Salahi, Mehrdad / Khoi, Maryam / Razzaghi, Reza / Banafshe, Hamid Reza / Alizadeh, Mostafa / Akhbari, Marzieh / Atharizadeh, Mina / Izadikhah, Akram / Elsagh, Mahin / Hossein Zade Ghahnavieh, Mahdi / Eghbalian, Fatemeh / Vanai, Azam / Izadi, Hossein / Moravej, Seyed Ali Al‐hadi / Jazayeri, Seyede Ferdos / Bayat, Houman / Emadi Koochak, Hamid / Zargaran, Arman

    Phytotherapy research. 2021 Nov., v. 35, no. 11

    2021  

    Abstract: Persian medicine has recommended clinical experiences and proper herbal remedies for prevention and treatment of microbial infections and respiratory diseases. An open‐label, randomized, controlled, multicenter trial was conducted at five hospitals in ... ...

    Abstract Persian medicine has recommended clinical experiences and proper herbal remedies for prevention and treatment of microbial infections and respiratory diseases. An open‐label, randomized, controlled, multicenter trial was conducted at five hospitals in Tehran and Isfahan provinces of Iran on 358 hospitalized adult patients. A total of 174 patients received standard care and 184 received herbal remedies (polyherbal decoction every 8 hr and two herbal capsules every 12 hr) plus standard care for 7 days. The primary clinical endpoint was the duration of hospital stay, and secondary outcomes were clinical improvement of symptoms based on self‐assessment questionnaire. Results demonstrated that these natural decoction and capsules treatment plus routine care significantly decreased duration of hospital dyspnea (3.291 day vs. 6.468 days), accelerated clinical improvement, and decreased symptoms such as dry cough, dyspnea, muscle pain, headache, fatigue, anorexia, chills, runny nose, sputum cough, and vertigo in the treatment group compared with standard‐care group. Significant effects of these polyherbal formulations on improving the symptoms of COVID‐19 could be incredibly promising for managing this pandemic with acceptable tolerability.
    Keywords COVID-19 infection ; adults ; anorexia ; clinical trials ; cough ; dyspnea ; headache ; hospitals ; muscles ; nose ; pandemic ; phytotherapy ; questionnaires ; research ; Iran
    Language English
    Dates of publication 2021-11
    Size p. 6295-6309.
    Publishing place John Wiley & Sons, Ltd.
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.7277
    Database NAL-Catalogue (AGRICOLA)

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