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Article ; Online: Multidisciplinary community paediatric video appointments during COVID-19 pandemic: descriptive study.

Mount, Charlotte Emma / Elson, Naomi / Ahmad, Salma

2020 Volume 106, Issue 3, Page(s) e19

MeSH term(s)	Adult ; Appointments and Schedules ; Attitude of Health Personnel ; Attitude to Health ; COVID-19/epidemiology ; COVID-19/prevention & control ; Child ; Child Health Services/organization & administration ; Child Health Services/standards ; Child Health Services/trends ; Disease Transmission, Infectious/prevention & control ; Humans ; Infection Control/methods ; Needs Assessment ; Parents/psychology ; Remote Consultation/methods ; Remote Consultation/organization & administration ; SARS-CoV-2 ; Social Perception ; United Kingdom
Keywords	covid19
Language	English
Publishing date	2020-09-10
Publishing country	England
Document type	Letter
ZDB-ID	524-1
ISSN	1468-2044 ; 0003-9888 ; 1359-2998
ISSN (online)	1468-2044
ISSN	0003-9888 ; 1359-2998
DOI	10.1136/archdischild-2020-320011
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Article: Multidisciplinary community paediatric video appointments during COVID-19 pandemic: descriptive study

Mount, Charlotte Emma / Elson, Naomi / Ahmad, Salma

Arch. dis. child

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #760229
Database	COVID19

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Article ; Online: Multidisciplinary community paediatric video appointments during COVID-19 pandemic

Mount, Charlotte Emma / Elson, Naomi / Ahmad, Salma

Archives of Disease in Childhood

descriptive study

2020 , Page(s) archdischild–2020–320011

Keywords	Pediatrics, Perinatology, and Child Health ; covid19
Language	English
Publisher	BMJ
Publishing country	uk
Document type	Article ; Online
ZDB-ID	524-1
ISSN	1468-2044 ; 0003-9888 ; 1359-2998
ISSN (online)	1468-2044
ISSN	0003-9888 ; 1359-2998
DOI	10.1136/archdischild-2020-320011
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: 'Love makes me feel good inside and my heart is fixed': What adults with intellectual disabilities have to say about love and relationships.

McCarthy, Michelle / Bates, Claire / Elson, Nicola / Hunt, Siobhan / Milne-Skillman, Karen / Forrester-Jones, Rachel

Journal of applied research in intellectual disabilities : JARID

2021 Volume 35, Issue 4, Page(s) 955–965

Abstract: Background: Adults with intellectual disabilities have historically been hindered, rather than supported, in their desire to form loving relationships. This paper sought to explore with them what kinds of support they wanted in the 21st Century.: ... ...

Abstract	Background: Adults with intellectual disabilities have historically been hindered, rather than supported, in their desire to form loving relationships. This paper sought to explore with them what kinds of support they wanted in the 21st Century. Method: Semi-structured in-depth interviews were conducted with 40 adults with intellectual disabilities in the United Kingdom. Results: Participants placed a high value on having a partner and being supported to maintain and develop a loving relationship. The factors which constrained them in achieving this included a lack of social opportunities, barriers created by social care services and limits on them exercising autonomy. Facilitating factors included access to specialist dating agencies, strong family and staff support and opportunities to learn about relationships. Conclusions: The importance of a loving relationship as a source of pleasure and meaning in the lives of adults with intellectual disabilities who are often disadvantaged in many other spheres of life is emphasised.
MeSH term(s)	Adult ; Emotions ; Humans ; Intellectual Disability ; Interpersonal Relations ; Love ; Social Support ; United Kingdom
Language	English
Publishing date	2021-05-25
Publishing country	England
Document type	Journal Article
ZDB-ID	1326222-1
ISSN	1468-3148 ; 0952-9608 ; 1360-2322
ISSN (online)	1468-3148
ISSN	0952-9608 ; 1360-2322
DOI	10.1111/jar.12893
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Article ; Online: Getting Real: The Maryland Healthcare Ethics Committee Network's COVID-19 Working Group Debriefs Lessons Learned.

Elson, Norton / Gwon, Howard / Hoffmann, Diane E / Kelmenson, Adam M / Khan, Ahmed / Kraus, Joanne F / Onyegwara, Casmir C / Povar, Gail / Sheikh, Fatima / Tarzian, Anita J

HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues

2021 Volume 33, Issue 1-2, Page(s) 91–107

Abstract: Responding to a major pandemic and planning for allocation of scarce resources (ASR) under crisis standards of care requires coordination and cooperation across federal, state and local governments in tandem with the larger societal infrastructure. ... ...

Abstract	Responding to a major pandemic and planning for allocation of scarce resources (ASR) under crisis standards of care requires coordination and cooperation across federal, state and local governments in tandem with the larger societal infrastructure. Maryland remains one of the few states with no state-endorsed ASR plan, despite having a plan published in 2017 that was informed by public forums across the state. In this article, we review strengths and weaknesses of Maryland's response to COVID-19 and the role of the Maryland Healthcare Ethics Committee Network (MHECN) in bridging gaps in the state's response to prepare health care facilities for potential implementation of ASR plans. Identified "lessons learned" include: Deliberative Democracy Provided a Strong Foundation for Maryland's ASR Framework; Community Consensus is Informative, Not Normative; Hearing Community Voices Has Inherent Value; Lack of Transparency & Political Leadership Gaps Generate a Fragmented Response; Pandemic Politics Requires Diplomacy & Persistence; Strong Leadership is Needed to Avoid Implementing ASR … And to Plan for ASR; An Effective Pandemic Response Requires Coordination and Information-Sharing Beyond the Acute Care Hospital; and The Ability to Correct Course is Crucial: Reconsidering No-visitor Policies.
MeSH term(s)	COVID-19/epidemiology ; COVID-19/prevention & control ; Delivery of Health Care/ethics ; Ethics Committees ; Humans ; Maryland/epidemiology ; Pandemics ; Resource Allocation/ethics ; SARS-CoV-2
Language	English
Publishing date	2021-02-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1042368-0
ISSN	1572-8498 ; 0956-2737
ISSN (online)	1572-8498
ISSN	0956-2737
DOI	10.1007/s10730-021-09442-y
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Article ; Online: Relationship of Coagulopathy and Platelet Dysfunction to Transfusion Needs After Traumatic Brain Injury.

Martin, Grace / Shah, Dhavan / Elson, Nora / Boudreau, Ryan / Hanseman, Dennis / Pritts, Timothy A / Makley, Amy T / Foreman, Brandon / Goodman, Michael D

Neurocritical care

2018 Volume 28, Issue 3, Page(s) 330–337

Abstract: Background: Coagulopathy and platelet dysfunction commonly develop after traumatic brain injury (TBI). Thromboelastography (TEG) and platelet function assays (PFAs) are often performed at the time of admission; however, their roles in assessing post-TBI ...

Abstract	Background: Coagulopathy and platelet dysfunction commonly develop after traumatic brain injury (TBI). Thromboelastography (TEG) and platelet function assays (PFAs) are often performed at the time of admission; however, their roles in assessing post-TBI coagulopathy have not been investigated. We hypothesized that compared to blunt TBI, penetrating TBI would (1) demonstrate greater coagulopathy by TEG, (2) be associated with abnormal PFA results, and (3) require more blood product transfusions. Methods: We performed a retrospective study of patients admitted to the neuroscience intensive care unit of a level 1 trauma center from 2013 to 2015 with head Abbreviated Injury Scale ≥3. Patients were compared by mechanism of injury (blunt vs. penetrating). Admission demographics, injury characteristics, and laboratory parameters were evaluated. VerifyNow Results: Five hundred and thirty-four patients were included in the analysis. There were no differences between groups in platelet count or international normalized ratio; however, patients with penetrating TBI were more coagulopathic by TEG, with all of the TEG parameters being significantly different except for R time. Patients with penetrating head trauma were not more likely than their blunt counterparts to have abnormal PFA results, and PFA results did not correlate with any TEG parameter in either group. The penetrating cohort received more units of blood products in the first 4 and 24 h than the blunt cohort. Conclusions: Patients presenting with penetrating TBI demonstrated increased coagulopathy compared to those with blunt TBI as measured by TEG and need for transfusion. PFA results did not correlate with TEG findings in this population.
MeSH term(s)	Adult ; Aged ; Blood Coagulation Disorders/etiology ; Blood Coagulation Disorders/therapy ; Blood Transfusion ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/therapy ; Female ; Head Injuries, Closed/complications ; Head Injuries, Closed/therapy ; Head Injuries, Penetrating/complications ; Head Injuries, Penetrating/therapy ; Humans ; International Normalized Ratio ; Male ; Middle Aged ; Platelet Function Tests ; Registries ; Retrospective Studies ; Thrombelastography ; Young Adult
Language	English
Publishing date	2018-01-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-017-0485-5
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Article ; Online: Prevalence of anemia and its relationship with neurological status in patients undergoing surgery for degenerative cervical myelopathy and radiculopathy: A retrospective study of 2 spine centers.

Nouri, Aria / Matur, Abhijith / Pennington, Zach / Elson, Nora / Karim Ahmed, A / Huq, Sakibul / Patel, Kishan / Jeong, William / Nasser, Rani / Tessitore, Enrico / Sciubba, Daniel M / Cheng, Joseph S

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2020 Volume 72, Page(s) 252–257

Abstract: Both degenerative cervical myelopathy (DCM) and anemia are common among older patients, however insufficient data exists evaluating their co-occurrence and the influence of anemia on baseline neurological status. To address this, we examined a ... ...

Abstract	Both degenerative cervical myelopathy (DCM) and anemia are common among older patients, however insufficient data exists evaluating their co-occurrence and the influence of anemia on baseline neurological status. To address this, we examined a retrospective multicenter series of patients treated for DCM or radiculopathy. Myelopathy was graded using the Nurick scale. Established criteria for diagnosing abnormalities were used to identify blood abnormalities, including macrocytic and microcytic anemia. Multivariable regression was used to determine the impact of hematological anomalies on Nurick grades. In our analysis, we included 725 patients (age of 57.1 ± 11.7), of whom 398 presented with myelopathy and 327 presented with radiculopathy alone. Twenty six percent of all patients were anemic at baseline and the mean preoperative Nurick grade across all patients was 2.09 ± 1.29; mean Nurick grade amongst those with DCM was 2.98 ± 1.12. Compared to those with myelopathy, patients with radiculopathy were significantly younger (53.8 ± 11.0 vs 59.8 ± 11.6, p < 0.001) and less likely to be anemic (16.8% vs 33.7%, p < 0.0001). Nurick grading was significantly higher in myelopathy patients with anemia (3.13 ± 1.19 vs 2.91 ± 1.07, p = 0.05) and macrocytic anemia (4.00 ± 1.41 vs 2.97 ± 1.11, p = 0.04). Multivariate regression demonstrated that anemia (p < 0.001), age (p < 0.0001), and posterior surgical approach (p < 0.0001) were related to worse preoperative Nurick grade. In sum, these data suggest that anemia and degenerative cervical spine pathologies commonly co-occur. Anemia, and macrocytic anemia specifically, is associated with poorer neurological status in myelopathic patients. These data suggest anemia may influence baseline neurological status and impact surgical recovery in patients treated for DCM or radiculopathy.
MeSH term(s)	Adult ; Aged ; Anemia/epidemiology ; Cervical Vertebrae/surgery ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Radiculopathy/complications ; Radiculopathy/pathology ; Radiculopathy/surgery ; Spondylosis/complications ; Spondylosis/pathology ; Spondylosis/surgery
Language	English
Publishing date	2020-01-03
Publishing country	Scotland
Document type	Journal Article ; Multicenter Study
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2019.11.027
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Article ; Online: Prehospital end-tidal carbon dioxide is predictive of death and massive transfusion in injured patients: An Eastern Association for Surgery of Trauma multicenter trial.

Campion, Eric M / Cralley, Alexis / Sauaia, Angela / Buchheit, Ron C / Brown, Austin T / Spalding, M Chance / LaRiccia, Aimee / Moore, Scott / Tann, Kimberly / Leskovan, John / Camazine, Maraya / Barnes, Stephen L / Otaibi, Banan / Hazelton, Joshua P / Jacobson, Lewis E / Williams, Jamie / Castillo, Roberto / Stewart, Nakosi J / Elterman, Joel B /

Zier, Linda / Goodman, Michael / Elson, Nora / Miner, Jason / Hardman, Claire / Kapoen, Carolijn / Mendoza, April E / Schellenberg, Morgan / Benjamin, Elizabeth / Wakam, Glenn K / Alam, Hasan B / Kornblith, Lucy Z / Callcut, Rachael A / Coleman, Lauren E / Shatz, David V / Burruss, Sigrid / Linn, Ann C / Perea, Lindsey / Morgan, Madison / Schroeppel, Thomas J / Stillman, Zachery / Carrick, Matthew M / Gomez, Mario F / Berne, John D / McIntyre, Robert C / Urban, Shane / Nahmias, Jeffry / Tay, Erika / Cohen, Mitchell / Moore, Ernest E / McVaney, Kevin / Burlew, Clay Cothren

The journal of trauma and acute care surgery

2021 Volume 92, Issue 2, Page(s) 355–361

Abstract: Background: Prehospital identification of the injured patient likely to require emergent care remains a challenge. End-tidal carbon dioxide (ETCO2) has been used in the prehospital setting to monitor respiratory physiology and confirmation of ... ...

Abstract	Background: Prehospital identification of the injured patient likely to require emergent care remains a challenge. End-tidal carbon dioxide (ETCO2) has been used in the prehospital setting to monitor respiratory physiology and confirmation of endotracheal tube placement. Low levels of ETCO2 have been demonstrated to correlate with injury severity and mortality in a number of in-hospital studies. We hypothesized that prehospital ETCO2 values would be predictive of mortality and need for massive transfusion (MT) in intubated patients. Methods: This was a retrospective multicenter trial with 24 participating centers. Prehospital, emergency department, and hospital values were collected. Receiver operating characteristic curves were created and compared. Massive transfusion defined as >10 U of blood in 6 hours or death in 6 hours with at least 1 U of blood transfused. Results: A total of 1,324 patients were enrolled. ETCO2 (area under the receiver operating characteristic curve [AUROC], 0.67; confidence interval [CI], 0.63-0.71) was better in predicting mortality than shock index (SI) (AUROC, 0.55; CI, 0.50-0.60) and systolic blood pressure (SBP) (AUROC, 0.58; CI, 0.53-0.62) (p < 0.0005). Prehospital lowest ETCO2 (AUROC, 0.69; CI, 0.64-0.75), SBP (AUROC, 0.75; CI, 0.70-0.81), and SI (AUROC, 0.74; CI, 0.68-0.79) were all predictive of MT. Analysis of patients with normotension demonstrated lowest prehospital ETCO2 (AUROC, 0.66; CI, 0.61-0.71), which was more predictive of mortality than SBP (AUROC, 0.52; CI, 0.47-0.58) or SI (AUROC, 0.56; CI, 0.50-0.62) (p < 0.001). Lowest prehospital ETCO2 (AUROC, 0.75; CI, 0.65-0.84), SBP (AUROC, 0.63; CI, 0.54-0.74), and SI (AUROC, 0.64; CI, 0.54-0.75) were predictive of MT in normotensive patients. ETCO2 cutoff for MT was 26 mm Hg. The positive predictive value was 16.1%, and negative predictive value was high at 98.1%. Conclusion: Prehospital ETCO2 is predictive of mortality and MT. ETCO2 outperformed traditional measures such as SBP and SI in the prediction of mortality. ETCO2 may outperform traditional measures in predicting need for transfusion in occult shock. Level of evidence: Diagnostic test, level III.
MeSH term(s)	Adolescent ; Adult ; Aged ; Blood Component Transfusion/statistics & numerical data ; Carbon Dioxide/metabolism ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Injury Severity Score ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Tidal Volume ; United States ; Vital Signs ; Wounds and Injuries/mortality
Chemical Substances	Carbon Dioxide (142M471B3J)
Language	English
Publishing date	2021-06-17
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	2651070-4
ISSN	2163-0763 ; 2163-0755
ISSN (online)	2163-0763
ISSN	2163-0755
DOI	10.1097/TA.0000000000003447
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Article: Nifedipine treatment of bolus esophageal obstruction.

Elson, N R / Taylor, I L

Gastrointestinal endoscopy

1986 Volume 32, Issue 5, Page(s) 371–372

MeSH term(s)	Esophageal Stenosis/drug therapy ; Humans ; Male ; Middle Aged ; Nifedipine/therapeutic use
Chemical Substances	Nifedipine (I9ZF7L6G2L)
Language	English
Publishing date	1986-10
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	391583-9
ISSN	1097-6779 ; 0016-5107
ISSN (online)	1097-6779
ISSN	0016-5107
DOI	10.1016/s0016-5107(86)71899-3
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Article: Production of fetal-like alkaline phosphatase by HeLa cells.

Elson, N A / Cox, R P

Biochemical genetics

1969 Volume 3, Issue 6, Page(s) 549–561

MeSH term(s)	Alkaline Phosphatase/analysis ; Alkaline Phosphatase/antagonists & inhibitors ; Amino Acids/pharmacology ; Antigen-Antibody Reactions ; Cell Line ; Culture Techniques ; Electrophoresis ; Enzyme Repression ; HeLa Cells/enzymology ; Heterozygote ; Humans ; Hydrogen-Ion Concentration ; Immunodiffusion ; Molecular Weight ; Neoplasms/metabolism ; Placenta/enzymology
Chemical Substances	Amino Acids ; Alkaline Phosphatase (EC 3.1.3.1)
Language	English
Publishing date	1969-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2168-4
ISSN	0006-2928
ISSN	0006-2928
DOI	10.1007/bf00485476
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