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Article ; Online: How frequently MRI modifies thoracolumbar fractures' classification or decision-making? A systematic review and meta-analysis.

Aly, Mohamed M / Soliman, Youssef / Elemam, Rmy A / Pizones, Javier / Alzahrani, Ahmed / Elwatidy, Sherif

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

2024 Volume 33, Issue 4, Page(s) 1540–1549

Abstract: Purpose: To provide the first meta-analysis of the impact of magnetic resonance imaging (MRI) on thoracolumbar fractures (TLFs) classification and decision-making.: Methods: A systematic review was conducted following PRISMA guidelines. We searched ... ...

Abstract	Purpose: To provide the first meta-analysis of the impact of magnetic resonance imaging (MRI) on thoracolumbar fractures (TLFs) classification and decision-making. Methods: A systematic review was conducted following PRISMA guidelines. We searched PubMed, Scopus, Cochrane, and Web of Science from inception to June 30, 2023 for studies evaluating the change in TLFs classification and treatment decisions after MRI. The studies extracted key findings, objectives, and patient population. A meta-analysis was performed for the pooled frequency of change in AO fracture classification or treatment decisions from surgical to conservative or vice versa after MRI. Results: This meta-analysis included four studies comprising 554 patients. The pooled frequency of change in TLFs classification was 17% (95% CI 9-31%), and treatment decision was 22% (95% CI 11-40%). An upgrade from type A to type B was reported in 15.7% (95% CI 7.2-30.6%), and downgrading type B to type A in 1.2% (95% CI 0.17-8.3%). A change from conservative to surgery recommendation of 17% (95% CI 5.0-43%) was higher than a change from surgery to conservative 2% (95% CI 1-34%). Conclusions: MRI can significantly change the thoracolumbar classification and decision-making, primarily due to upgrading type A to type B fractures and changing from conservative to surgery, respectively. These findings suggest that MRI could change decision-making sufficiently to justify its use for TLFs. Type A subtypes, indeterminate PLC status, and spine regions might help to predict a change in TLFs' classification. However, more studies are needed to confirm the association of these variables with changes in treatment decisions to set the indications of MRI in neurologically intact patients with TLFs. An interactive version of our analysis can be accessed from here: https://databoard.shinyapps.io/mri_spine/ .
MeSH term(s)	Humans ; Spinal Fractures/diagnostic imaging ; Spinal Fractures/surgery ; Spinal Fractures/complications ; Lumbar Vertebrae/surgery ; Thoracic Vertebrae/surgery ; Fractures, Bone/complications ; Magnetic Resonance Imaging/methods
Language	English
Publishing date	2024-02-12
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	1115375-1
ISSN	1432-0932 ; 0940-6719
ISSN (online)	1432-0932
ISSN	0940-6719
DOI	10.1007/s00586-023-08087-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Ten-year survival in glioblastoma patient with neurofibromatosis type 1: illustrative case.

Basindwah, Sarah / Alkhalidi, Hisham / Abdelwarith, Ahmed / Elwatidy, Sherif

Journal of neurosurgery. Case lessons

2022 Volume 3, Issue 4

Abstract: Background: Gliomas are commonly detected in patients with neurofibromatosis type 1 (NF1) at an early age. Few patients with NF1 are diagnosed with glioblastoma. The course of management, response to therapy, and prognosis of such patients are unknown. ... ...

Abstract	Background: Gliomas are commonly detected in patients with neurofibromatosis type 1 (NF1) at an early age. Few patients with NF1 are diagnosed with glioblastoma. The course of management, response to therapy, and prognosis of such patients are unknown. Few reports have shown longer-than-average survival rates for patients with NF1 with glioblastoma. Observations: A 27-year-old man with NF1 presented with symptoms of high intracranial pressure. Imaging and pathology showed left frontotemporal glioblastoma. Gross total resection was achieved, and concurrent chemoradiotherapy was administered. Recurrence of tumor was detected 48 months later, and the patient underwent tumor debulking and concurrent chemoradiotherapy. The patient received first-, second-, and third-line chemotherapy (temozolomide, bevacizumab, bevacizumab/irinotecan) with good tolerance and has survived >10 years since then with good functional status. Lessons: This case demonstrates >10 years overall survival of glioblastoma in a patient with NF1. Reports of patients with NF1 with longer survival may be attributed to the young age at diagnosis and relatively better tolerance for therapy. It might also support the growing evidence of a unique subset of glioblastoma associated with NF1 and opens the door for a more molecular targeted therapy in the future.
Language	English
Publishing date	2022-01-24
Publishing country	United States
Document type	Journal Article
ISSN	2694-1902
ISSN (online)	2694-1902
DOI	10.3171/CASE21630
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Article ; Conference proceedings: Tumors of the Lateral and Third Ventricle in Children: Surgical Management and Outcome Analysis

Al Towim, Abdullah / Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2022 Volume 83, Issue S 01

Event/congress	31st Annual Meeting North American Skull Base Society, Online, 2022-02-18
Language	English
Publishing date	2022-02-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0042-1743776
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Article ; Conference proceedings: Subfascial Soft-Tissue Dissection in Pterional Craniotomies: A Technical Note

Ajlan, Abdulrazag / Basindwah, Sarah / Alqurashi, Ashwag / Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2023 Volume 84, Issue S 01

Event/congress	32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
Language	English
Publishing date	2023-02-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0043-1762415
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Article ; Online: Intraosseous meningioma, a rare presentation of a common brain tumor: illustrative case.

Elwatidy, Sherif / Alanazi, Abdulaziz / Alanazi, Rahaf F / Alraddadi, Khulood K

Journal of neurosurgery. Case lessons

2022 Volume 4, Issue 15

Abstract: Background: The subset of extradural meningiomas arising from bone is called primary intraosseous meningioma. The present article outlines the clinical presentation, investigation, surgical management, and clinical outcomes of a challenging case of ... ...

Abstract	Background: The subset of extradural meningiomas arising from bone is called primary intraosseous meningioma. The present article outlines the clinical presentation, investigation, surgical management, and clinical outcomes of a challenging case of intraosseous meningioma. Observations: A 27-year-old male presented with new-onset seizure of 3 years' duration and growing painless hard swelling involving the left frontoparietal bone, the medial aspect of the left orbit, the nasal bone, and the temporal bone. Brain computed tomography showed a diffuse intradiploic space osseous lesion with a ground-glass appearance. The patient underwent bifrontal craniotomy and tumor excision. The histopathological sections showed the presence of classic whorls of meningothelial cells around reactive bony tissue suggestive of intraosseous meningioma. Postoperatively, the patient was neurologically intact, and he was discharged in a stable condition. The outcome of this case was satisfactory. Lessons: The treatment of primary intraosseous meningioma is wide surgical excision together with the involved dura and any intradural tumor. The location of the tumor determines the approach and the amount of resection, keeping in mind preservation of function. The use of adjuvant therapy is reserved for cases of tumor recurrence or an atypical type.
Language	English
Publishing date	2022-10-10
Publishing country	United States
Document type	Journal Article
ISSN	2694-1902
ISSN (online)	2694-1902
DOI	10.3171/CASE22331
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Article: Lhermitte-Duclos disease: A systematic review.

Alanazi, Aued Iaed / Alanezi, Tariq / Aljofan, Ziyad Fahad / Alarabi, Alwaleed / Elwatidy, Sherif

Surgical neurology international

2023 Volume 14, Page(s) 351

Abstract: Background: Lhermitte-Duclos disease (LDD) is a rare tumor, with only about 300 reported cases. It often shows comorbidity with Cowden syndrome (CS); however, it can occur by itself. Radiologically, the "tiger-stripe" appearance is considered ... ...

Abstract	Background: Lhermitte-Duclos disease (LDD) is a rare tumor, with only about 300 reported cases. It often shows comorbidity with Cowden syndrome (CS); however, it can occur by itself. Radiologically, the "tiger-stripe" appearance is considered pathognomonic. Surgical resection remains the mainstay of treatment. This report aims to describe the clinical and radiological characteristics of LDD and its relationship with CS according to age group. Methods: PubMed electronic databases were searched in August 2022. The search terms included "Lhermitte- Duclos disease" and "dysplastic gangliocytoma," which yielded 297 and 103 research articles, respectively. The articles were collected and reviewed by three researchers. Results: Out of 400 identified articles, we analyzed 302 reported cases. The mean age at presentation was 33.6 ± 16 years; 171 patients (56.6%) were female, and 123 (40.7%) were male. The most commonly reported symptom was headache (174 patients, 57.6%), followed by ataxia (109, 36.1%). In addition, 99 cases (32.8%) were associated with CS, and 60 (19.9%) had a confirmed phosphatase and tensin homolog ( Conclusion: Our findings suggest that adult and pediatric LDD have major commonalities; however, further prospective studies are warranted.
Language	English
Publishing date	2023-09-29
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2229-5097
ISSN	2229-5097
DOI	10.25259/SNI_555_2023
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Conference proceedings: Fontal Sinus Osteoma: A Huge Craniofacial Tumor Preoperative Planning and Strategy of Surgical Excision and Reconstruction

Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2016

Abstract: Osteomas are the most common fibro-osseous lesions in the paranasal sinus. They are benign tumors characterized by slow growth and are often asymptomatic. Treatment is indicated in sphenoid osteomas that threaten the optic canal or orbital apex and in ... ...

Event/congress	Presentation Abstracts, Fairmont Scottsdale Princess Scottsdale, Arizona, 2016
Abstract	Osteomas are the most common fibro-osseous lesions in the paranasal sinus. They are benign tumors characterized by slow growth and are often asymptomatic. Treatment is indicated in sphenoid osteomas that threaten the optic canal or orbital apex and in symptomatic cases. We report a case of a giant frontal sinus osteoma with orbital invasion treated by a combined open craniofacial approach with reconstruction of the anterior cranial base and orbital walls. Immediate reconstruction allows aesthetic and functional restoration of neighboring structures, which should one of the goals in the treatment of this benign entity. The literature is reviewed and aetiopathogenic theories, diagnostic procedures and surgical approaches are discussed. The choice of surgical management depends on the location, size and experience of the surgeon. An open approach allows tumor removal with direct visual control and remains the best option in large tumors, but the continued progression in endoscopic approaches is responsible for new indications in closed techniques.
Language	English
Publishing date	2016-03-03
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0036-1580013
Database	Thieme publisher's database

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Article ; Conference proceedings: Giant Craniofacial Osteoma: Preoperative Planning and Strategy of Surgical Excision and Reconstruction

Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2016

Abstract: 22 years old girl presented with huge frontal sinus osteoma destroying the craniofacial bones, both orbits, nasal bone and skull base causing severe proptosis, impaired vision and recurrent peri-orbital cellulitis. Radiologic investigations included CT ... ...

Event/congress	Presentation Abstracts, Fairmont Scottsdale Princess Scottsdale, Arizona, 2016
Abstract	22 years old girl presented with huge frontal sinus osteoma destroying the craniofacial bones, both orbits, nasal bone and skull base causing severe proptosis, impaired vision and recurrent peri-orbital cellulitis. Radiologic investigations included CT scan with 3 –D reconstruction, MRI brain scan, MRA and MRV, cerebral angiogram, and Endoscopic biopsy. Preoperative planning: neurosurgery, ophthalmology, ENT, Plastic Surgery, and Craniofacial surgery teams were involved in clinical evaluation and surgical planning. Reconstruction of craniofacial defect after excision of this huge tumor was the main challenge. Pre-operative 3-D skull model with and without tumor was designed and a PEEK prosthesis was made to reconstruct the huge defect that involved frontal bones, skull base, both orbits, and nasal bones. Postoperative course was smooth, uneventful with no complication. Hospital stay after surgery was short (10 days) and the outcome was excellent. Conclusion: Careful preoperative multidisciplinary planning and surgical approach is crucial in huge craniofacial tumors; it makes surgical excision easy, minimizes postoperative complications, reduces hospital stay and achieves the best cosmetic results and outcome. Fig. 1: Fig. 2:
Keywords	osteoma ; paranasal sinuses ; skull base ; craniofacial ; surgical excision ; reconstruction
Language	English
Publishing date	2016-03-03
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0036-1580050
Database	Thieme publisher's database

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Location:
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ab Jg. 2022: Lesesaal (EG)

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Article ; Conference proceedings: Is Pterional Craniotomy Adequate for Complete Excision of Olfactory Groove Meningioma

Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2014

Abstract: Objective: This study aims to study the feasibility of complete surgical excision of olfactory groove meningioma (OGM) through pterional craniotomy (PC). : Patients and Methods: We reviewed all patients with OGM who had surgical excision through PC ... ...

Event/congress	11th European Skull Base Society Congress: Beyond the Limits, Paris, 2014
Abstract	Objective: This study aims to study the feasibility of complete surgical excision of olfactory groove meningioma (OGM) through pterional craniotomy (PC). Patients and Methods: We reviewed all patients with OGM who had surgical excision through PC at KKUH during the period Januray, 1990 to December, 2012, data of clinical presentation, radiological features, surgical procedure, outcome of surgery, and tumor recurrence were collected and analyzed. Results: There were 40 patients, 18% males and 82% females; the median age was 44 years. The tumor size was < 3 cm in 12%, 3 to 5 cm in 58%, and > 5 cm in 30% of patients. Pterional approach was used in all patients. The author excluded patients with OGM who had surgery through other approaches (bifrontal approach, supraorbital approach, and combined approaches). Total resection (Simpson grade I) was achieved in all patients. Postoperative complications included CSF collection, superficial wound infection in one patient, postoperative seizures in two patients, EDH in one patient, and DVT in one patient. Follow-up period ranged from 6 months to 10 years (mean, 43 months). Tumor recurrence was seen in 10% of patients. Conclusion: Pterional craniotomy is adequate for complete excision of OGM, it allows minimal brain exposure and manipulation with minimal postoperative brain swelling, complete removal with excellent neurosurgical outcome, minimal permanent morbidity and low recurrence rates.
Language	English
Publishing date	2014-06-17
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0034-1383989
Database	Thieme publisher's database

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Article ; Conference proceedings: Bifrontal Decompressive Craniectomy is a Life Saving Procedure for Patients with Nontraumatic Refractory Brain Edema

Elwatidy, Sherif

Journal of Neurological Surgery Part B: Skull Base

2014

Abstract: Objective: To study the outcome of bifrontal decompressive craniectomy (BDC) for treatment of nontraumatic refractory brain edema (RBE). : Patients and Methods: We reviewed clinical, radiological data of all patients who had BDC for treatment of RBE ... ...

Event/congress	11th European Skull Base Society Congress: Beyond the Limits, Paris, 2014
Abstract	Objective: To study the outcome of bifrontal decompressive craniectomy (BDC) for treatment of nontraumatic refractory brain edema (RBE). Patients and Methods: We reviewed clinical, radiological data of all patients who had BDC for treatment of RBE and herniation syndrome. Results: Five patients all of them deteriorated to GCS 4-5/15 and had their pupils dilated and fixed before surgery. The primary pathology was aneurysmal SAH in two patients, CNS infection in two patients, and one large calcified olfactory groove meningioma. The follow-up ranged from 6 months to 7 years, mean 3.9; there were no complications related to bone flap, no mortality or vegetative patients, one patient (20%) had good outcome, two patients (40%) had moderate disability (independent), and two patients had severe disability (dependent) (40%). Conclusion: BDC is an effective method of surgical decompression in patients with RBE; the procedure should be performed quickly after clinical deterioration to prevent irreversible secondary brain damage. Although, difficult to accomplish, a randomized clinical trial is necessary to define criteria for surgical interference in patients with nontraumatic RBE.
Language	English
Publishing date	2014-06-17
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0034-1384089
Database	Thieme publisher's database

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