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Article ; Online: Aspects epidemiologiques, cliniques, evolutifs et facteurs de risque de l’erysipele dans trois hopitaux de Nouakchott-Mauritanie.

Kebe, M / Soufiane, S A / Cheikh, D / Amar, M L / Yahya, S / Ely, S O / Ball, M

2024 Volume 36, Issue 4, Page(s) 65–69

Abstract: Introduction: Erysipelas is an acute non-necrotizing dermohypoderma of bacterial origin, mainly due to streptococcus. Its elective topography is the leg, it is a frequent reason for consultation and hospitalization in medicine. This is a potentially ... ...

Title translation	Epidemiological, clinical, evolutionary and risk factors of erysipelas in three hospitals in Nouakchott-Mauritania.
Abstract	Introduction: Erysipelas is an acute non-necrotizing dermohypoderma of bacterial origin, mainly due to streptococcus. Its elective topography is the leg, it is a frequent reason for consultation and hospitalization in medicine. This is a potentially serious medical emergency that can be life threatening. Our study aims to determine the epidemiological and clinical characteristics, as well as the risk and prognosis factors of erysipelas in Mauritania. Patients and methods: This was a cross-sectional descriptive observational study from January 01, 2016 to July 30, 2017. The study population was represented by patients seen for an acute inflammatory placard, hot, painful and feverish. Results: In the 61 patients, the mean age was 40 years with extremes of 1 and 73 years. A female predominance was observed. The locations were one-sided. In 93.4% of cases, erysipelas was found in the lower limbs. Satellite lymphadenopathy was present in 40 patients, ie 66% of cases. A fever greater than or equal to 38 ° C was observed in 87% of cases, it was associated with chills 10% of cases. Local risk factors are represented by a traumatic wound, acute eczema and intertrigo inter toe. General factors are obesity, taking nonsteroidal anti-inflammatory drugs and artificial depigmentation. The outcome of our patients is favorable in 95% of cases on antibiotics. 9 patients presented with abscess during the course, ie 15%. Conclusion: In our study, erysipelas was observed mainly in a young housewife in her forties. Clinically, the preferred location was that of the leg found in 93.4%. Several risk factors are associated with erysipelas in our study.
Language	French
Publishing date	2024-01-10
Publishing country	Mali
Document type	English Abstract ; Journal Article
ZDB-ID	2502651-3
ISSN	1993-0836 ; 1993-0836
ISSN (online)	1993-0836
ISSN	1993-0836
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Informed consent and birth preparedness/complication readiness: A qualitative study at two tertiary maternity units.

Ely, Sally / Langer, Susanne / Dietz, Hans Peter

The Australian & New Zealand journal of obstetrics & gynaecology

2021 Volume 62, Issue 1, Page(s) 47–54

Abstract: Background: Informed consent in obstetrics should involve full disclosure of risks, benefits and alternative interventions. However, we have found no evidence of a formal informed consent process before an attempt at vaginal delivery in published policy ...

Abstract	Background: Informed consent in obstetrics should involve full disclosure of risks, benefits and alternative interventions. However, we have found no evidence of a formal informed consent process before an attempt at vaginal delivery in published policy or practice. The idea of informed consent in vaginal birth has attracted controversy and has been the subject of some debate. Aim: To explore the perspectives and experiences of informed consent and birth preparedness/complication readiness for birthing women in a high resource setting. Materials and methods: Qualitative study using semi-structured interviews to examine experiences and perspectives of women following birth. Results: Forty telephone interviews were concluded. Eight statement categories were identified: (i) no issues of consent, (ii) absent/inadequate informed consent, (iii) adequate birth preparedness/complication readiness, (iv) inadequate birth preparedness/complication readiness, (v) desire to forfeit decision making to a trusted and accountable health professional, (vi) belief that informed consent is not realistic in birth under some circumstances, (vii) negative feelings related to birth and (viii) poor postnatal follow-up. Conclusions: When complications arose during birth, 20% of participants felt that informed consent was absent/inadequate, 25% of participants suggested policy change in favour of a formal informed consent process and 55% of participants suggested policy change in favour of increased birth preparedness/complication readiness. Our study suggests that informed consent for vaginal birth and formal birth preparedness/complication readiness should form part of routine antenatal care. Women's preferences for decision-making and informed consent should be established before birth.
MeSH term(s)	Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Informed Consent ; Pregnancy ; Pregnant Women ; Prenatal Care
Language	English
Publishing date	2021-08-29
Publishing country	Australia
Document type	Journal Article
ZDB-ID	390815-x
ISSN	1479-828X ; 0004-8666
ISSN (online)	1479-828X
ISSN	0004-8666
DOI	10.1111/ajo.13417
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Book ; Online: Ted Hughes's South Yorkshire

Ely, Steve

Made in Mexborough

2015

Abstract: Ted Hughes's South Yorkshire tells the untold story of Hughes's Mexborough period (1938-1951) and demonstrates conclusively that Hughes's experiences in South Yorkshire - in town and country, educationally, in literature and love - were decisive in ... ...

Abstract	Ted Hughes's South Yorkshire tells the untold story of Hughes's Mexborough period (1938-1951) and demonstrates conclusively that Hughes's experiences in South Yorkshire - in town and country, educationally, in literature and love - were decisive in forming him as the poet of his subsequent fame
Language	English
Size	Online-Ressource (244 p)
Publisher	Palgrave Macmillan
Publishing place	Basingstoke
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9781137499349 ; 1137499346
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Renewed interest in myeloma tumor growth, or just one more method to assess proliferation?

Ely, Scott

Leukemia research

2011 Volume 35, Issue 1, Page(s) 30–31

MeSH term(s)	Cell Proliferation ; Humans ; Multiple Myeloma/genetics ; Multiple Myeloma/pathology
Language	English
Publishing date	2011-01
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	752396-8
ISSN	1873-5835 ; 0145-2126
ISSN (online)	1873-5835
ISSN	0145-2126
DOI	10.1016/j.leukres.2010.07.029
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Article ; Online: 'Normal birth': Time to change our tune?

Ely, Sally / Shek, Ka Lai / Dietz, Hans Peter

The Australian & New Zealand journal of obstetrics & gynaecology

2020 Volume 60, Issue 5, Page(s) 810–812

Abstract: Recent research indicates that atraumatic 'normal vaginal birth' only occurs in 33-40% of women who intend to achieve a vaginal delivery, depending on how the term 'normal birth' is defined. In contrast, the NSW birth policy continues to promote 'normal ... ...

Abstract	Recent research indicates that atraumatic 'normal vaginal birth' only occurs in 33-40% of women who intend to achieve a vaginal delivery, depending on how the term 'normal birth' is defined. In contrast, the NSW birth policy continues to promote 'normal birth', suggesting that the majority of women will achieve 'normal birth' and that 'normal birth' produces optimal maternal outcomes. Our continued use of the term 'normal birth' may be outdated. This article will consider the term 'normal birth' with regard to history, politics, policy and obstetric practice, and recommend a reconsideration of terminology.
MeSH term(s)	Delivery, Obstetric ; Female ; Humans ; Parturition ; Pregnancy
Language	English
Publishing date	2020-08-12
Publishing country	Australia
Document type	Journal Article
ZDB-ID	390815-x
ISSN	1479-828X ; 0004-8666
ISSN (online)	1479-828X
ISSN	0004-8666
DOI	10.1111/ajo.13223
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Article ; Online: A refined procedure for esophageal resection using a full minimally invasive approach.

Ashiku, Simon K / Patel, Ashish R / Horton, Brandon H / Velotta, Jeffrey / Ely, Sora / Avins, Andrew L

Journal of cardiothoracic surgery

2022 Volume 17, Issue 1, Page(s) 29

Abstract: Objective: Newer minimally invasive approaches to esophagectomy have brought substantial benefits to esophageal-cancer patients and continue to improve. We report here our experience with a streamlined procedure as part of a comprehensive perioperative- ... ...

Abstract	Objective: Newer minimally invasive approaches to esophagectomy have brought substantial benefits to esophageal-cancer patients and continue to improve. We report here our experience with a streamlined procedure as part of a comprehensive perioperative-care program that provides additional advances in the continued evolution of this procedure. Methods: All patients with primary esophageal cancer referred for resection to the Oakland Medical Center of the Kaiser-Permanente Northern California health plan who underwent this approach between January 2013 and August 2018 were included. Operative and clinical outcome variables were extracted from the electronic medical record, operating-room files, and manual chart review. Results: 142 patients underwent the new procedure and care program; 121 (85.2%) were men with mean age of 64.5 years. 127 (89.4%) were adenocarcinoma; 117 (82.4%) were clinical stage III or IVA. 115 (81.0%) required no jejunostomy. Median hospital length-of-stay was 3 days and 8 (5.6%) patients required admission to the intensive care unit. Postoperative complications occurred in 22 (15.5%) patients within 30 days of the procedure. There were no inpatient deaths; one patient (0.7%) died within 30 days following discharge and three additional deaths (2.1%) occurred through 90 days of follow-up. Conclusions: This approach resulted in excellent clinical outcomes, including short hospital stays with limited need for the intensive care unit, few perioperative complications, and relatively few patients requiring feeding tubes on discharge. This comprehensive approach to esophagectomy is feasible and provides another clinically meaningful advance in the progress of minimally invasive esophagectomy. Further development and dissemination of this method is warranted.
MeSH term(s)	Adenocarcinoma/surgery ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagectomy/methods ; Humans ; Laparoscopy/methods ; Length of Stay ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures ; Postoperative Complications/etiology ; Retrospective Studies ; Thoracoscopy/methods ; Treatment Outcome
Language	English
Publishing date	2022-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2227224-0
ISSN	1749-8090 ; 1749-8090
ISSN (online)	1749-8090
ISSN	1749-8090
DOI	10.1186/s13019-022-01765-2
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Article: Thermoregulatory behavior of lekking male desert locusts, Schistocerca gregaria, in the Sahara Desert.

Maeno, Koutaro Ould / Ould Ely, Sidi / Ould Mohamed, Sid'Ahmed / Jaavar, Mohamed El Hacen / Ould Babah Ebbe, Mohamed Abdallahi

Journal of thermal biology

2023 Volume 112, Page(s) 103466

Abstract: Most terrestrial animals are constrained by extreme heat conditions such as midday desert environments, while a few terrestrial ectothermic insects are active in such ecological niches. Sexually mature males of the desert locust (Schistocerca gregaria) ... ...

Abstract	Most terrestrial animals are constrained by extreme heat conditions such as midday desert environments, while a few terrestrial ectothermic insects are active in such ecological niches. Sexually mature males of the desert locust (Schistocerca gregaria) in the Sahara Desert remain on the open ground, despite the ground temperatures exceeding their lethal limit, to form leks and to mate incoming gravid females during the daytime. Lekking male locusts apparently suffer from extreme heat stress and greatly fluctuating thermal conditions. The present study examined the thermoregulatory strategies of the lekking male S. gregaria. Our field observations showed that lekking males changed their body orientation toward the sun depending on the temperature and time of day. In the relatively cool morning, males basked by orienting perpendicular to the sun's rays, maximizing the area of body surface exposed to the sun's rays. In contrast, around midday, when the ground surface temperature exceeded lethal high temperatures, some males tended to shelter inside the plants or remain in the shade. However, the remainder stayed on the ground, stilted (i.e., extending their legs to raise their bodies off the hot ground) and oriented parallel to the sun's rays, which minimized radiative heating. Measurements of body temperature throughout the hot middle period of the day confirmed that the stilting posture prevented overheating. Their critical lethal body temperature was as high as 54.7 °C. In this lekking system, gravid females enter male leks by flying. These incoming females usually landed on open ground, whereupon nearby males immediately approached, mounted, and mated the female, implying that males with greater heat-tolerance can increase mating chance. These results suggest that behavioral thermoregulation and physiologically high heat tolerance of male desert locusts allows them to endure extreme thermal conditions for lekking.
MeSH term(s)	Female ; Animals ; Male ; Grasshoppers/physiology ; Reproduction ; Body Temperature Regulation ; Africa, Northern
Language	English
Publishing date	2023-01-26
Publishing country	England
Document type	Journal Article
ZDB-ID	1498364-3
ISSN	1879-0992 ; 0306-4565
ISSN (online)	1879-0992
ISSN	0306-4565
DOI	10.1016/j.jtherbio.2023.103466
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Article ; Online: Effect of Thoracic Surgery Regionalization on 1- and 3-Year Survival after Cancer Esophagectomy.

Ely, Sora / Alabaster, Amy / Dominguez, Dana A / Maxim, Clara / Ashiku, Simon K / Patel, Ashish R / Velotta, Jeffrey B

Annals of surgery

2023 Volume 277, Issue 2, Page(s) e305–e312

Abstract: Objective: The aim of this study was to investigate whether our previously reported improvements in short-term cancer esophagectomy outcomes after large-scale regionalization in the United States translated to longer-term survival benefit.: Background! ...

Abstract	Objective: The aim of this study was to investigate whether our previously reported improvements in short-term cancer esophagectomy outcomes after large-scale regionalization in the United States translated to longer-term survival benefit. Background: Regionalization is associated with better early postoperative outcomes following cancer esophagectomy; however, data regarding its effect on long-term survival are mixed. Methods: We retrospectively reviewed 461 patients undergoing cancer esophagectomy before (2009-2013, N = 272) and after (2014-2016, N = 189) regionalization. Kaplan-Meier curves and chi-square tests were used to describe 1- and 3-year survival in each era. Hierarchical logistic regression models examined the adjusted effect of regionalization on mortality. Results: Compared to pre-regionalization patients, post-regionalization patients had significantly higher 1-year survival (83.1% vs 73.9%, P = 0.02) but not 3-year survival (52.9% vs 58.2%, P = 0.26).Subgroup analysis by cancer stage revealed that 1-year survival benefit was only significant among mid-stage (IIB-IIIB) patients, whereas differences in 3-year survival only approached significance among early-stage (IA-IIA) patients.In multivariable analysis, only regionalization was a predictor of lower mortality at 1 year [odds ratio (OR) 0.54, 95% confidence interval (CI) 0.29-1.00], and only thoracic specialty at 3years (OR 0.62, 95% CI 0.38-0.99). Older age, more advanced stage, and complications were associated with higher 1- and 3-year mortality. Comorbidity, minimally invasive approach, surgeon volume, facility volume, and neoadjuvant treatment were not significant in this model. Conclusions: Regionalization was associated with improved 1-year survival after cancer esophagectomy, independent of factors such as morbidity or volume in our adjusted models. This survival benefit did not persist at 3 years, likely due to the aggressive nature of the disease.
MeSH term(s)	Humans ; Esophageal Neoplasms ; Retrospective Studies ; Thoracic Surgery ; Esophagectomy ; Neoplasm Staging
Language	English
Publishing date	2023-01-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	340-2
ISSN	1528-1140 ; 0003-4932
ISSN (online)	1528-1140
ISSN	0003-4932
DOI	10.1097/SLA.0000000000005076
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Article ; Online: Overall survival in low-comorbidity patients with stage I non-small cell lung cancer who chose stereotactic body radiotherapy compared to surgery.

Udelsman, Brooks V / Canavan, Maureen E / Zhan, Peter L / Ely, Sora / Park, Henry S / Boffa, Daniel J / Mase, Vincent J

The Journal of thoracic and cardiovascular surgery

2023 Volume 167, Issue 3, Page(s) 822–833.e7

Abstract: Objective: To evaluate trends in the utilization of stereotactic body radiotherapy (SBRT) and to compare overall survival (OS) of patients with early-stage non-small cell lung cancer (NSCLC) undergoing SBRT versus those undergoing surgery.: Methods: ... ...

Abstract	Objective: To evaluate trends in the utilization of stereotactic body radiotherapy (SBRT) and to compare overall survival (OS) of patients with early-stage non-small cell lung cancer (NSCLC) undergoing SBRT versus those undergoing surgery. Methods: The National Cancer Database was queried for patients without documented comorbidities who underwent surgical resection (lobectomy, segmentectomy, or wedge resection) or SBRT for clinical stage I NSCLC between 2012 and 2018. Peritreatment mortality and 5-year OS were compared among propensity score-matched cohorts. Results: A total of 30,658 patients were identified, including 24,729 (80.7%) who underwent surgery and 5929 (19.3%) treated with SBRT. Between 2012 and 2018, the proportion of patients receiving SBRT increased from 15.9% to 26.0% (P < .001). The 30-day mortality and 90-day mortality were higher among patients undergoing surgical resection versus those receiving SBRT (1.7% vs 0.3%, P < .001; 2.8% vs 1.7%, P < .001). In propensity score-matched patients, OS favored SBRT for the first several months, but this was reversed before 1 year and significantly favored surgical management in the long term (5-year OS, 71.0% vs 41.8%; P < .001). The propensity score-matched analysis was repeated to include only SBRT patients who had documented refusal of a recommended surgery, which again demonstrated superior 5-year OS with surgical management (71.4% vs 55.9%; P < .001). Conclusions: SBRT is being increasingly used to treat early-stage lung cancer in low-comorbidity patients. However, for patients who may be candidates for either treatment, the long-term OS favors surgical management.
MeSH term(s)	Humans ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Carcinoma, Non-Small-Cell Lung/surgery ; Lung Neoplasms/pathology ; Radiosurgery ; Neoplasm Staging ; Small Cell Lung Carcinoma/surgery ; Comorbidity
Language	English
Publishing date	2023-07-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2023.07.021
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Article ; Online: So Now We Know-Reflections on the Extent of Resection for Stage I Lung Cancer.

Detterbeck, Frank / Ely, Sora / Udelsman, Brooks / Blasberg, Justin / Boffa, Daniel / Dhanasopon, Andrew / Mase, Vincnet / Woodard, Gavitt

Clinical lung cancer

2023

Abstract: Lobectomy has been the standard treatment for stage I lung cancer in healthy patients, largely based on a randomized trial published in 1995. Nevertheless, research has continued regarding the role of sublobar resection. Three additional randomized ... ...

Abstract	Lobectomy has been the standard treatment for stage I lung cancer in healthy patients, largely based on a randomized trial published in 1995. Nevertheless, research has continued regarding the role of sublobar resection. Three additional randomized trials addressing resection extent in healthy patients have recently been published. These 4 trials involve differences in design, eligibility, interventions, and intraoperative processes. Patients were ineligible if intraoperative assessment demonstrated stage > IA or inadequate resection margins. All trials consistently show no differences in perioperative morbidity, mortality, and postoperative changes in lung function between sublobar resection and lobectomy-consistent with other nonrandomized evidence. Long-term outcomes are generally encouraging of lesser resection, but some inconsistencies are apparent. The 2 larger recent trials demonstrated no overall survival difference while the others suggested better survival after lobectomy versus sublobar resection. Recurrence-free survival was found to be the same after lobectomy versus sublobar resection in 3 trials, despite higher locoregional recurrences after sublobar resection. The low 5-year recurrence-free survival (64%, regardless of resection extent) in 1 recent trial highlights the need for further optimization. Thus, there is high-level evidence that sublobar resection is a reasonable alternative to lobectomy in healthy patients. However, variability in long-term results suggests that aspects of patients, tumors and interventions need to be better understood. Therefore, we propose to apply sublobar resection cautiously; especially because there are no short-term benefits. Sublobar resection requires careful attention to intraoperative details (nodes, margins), and may be best suited for less aggressive (eg, ground glass, slow growing) tumors.
Language	English
Publishing date	2023-12-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2145146-1
ISSN	1938-0690 ; 1525-7304
ISSN (online)	1938-0690
ISSN	1525-7304
DOI	10.1016/j.cllc.2023.12.007
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