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  1. Article ; Online: The relationship between multidimensional poverty, income poverty and youth depressive symptoms

    Crick Lund / Ricardo Araya / Philipp Hessel / Annie Zimmerman / Emily Garman / Mauricio Avendano-Pabon / Sara Evans-Lacko / Yadira Diaz / Juliana Sanchez

    BMJ Global Health, Vol 7, Iss

    cross-sectional evidence from Mexico, South Africa and Colombia

    2022  Volume 1

    Keywords Medicine (General) ; R5-920 ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Concise Review of Nickel Human Health Toxicology and Ecotoxicology

    Samuel Buxton / Emily Garman / Katherine E. Heim / Tara Lyons-Darden / Christian E. Schlekat / Michael D. Taylor / Adriana R. Oller

    Inorganics, Vol 7, Iss 7, p

    2019  Volume 89

    Abstract: Nickel (Ni) metal and Ni compounds are widely used in applications like stainless steel, alloys, and batteries. Nickel is a naturally occurring element in water, soil, air, and living organisms, and is essential to microorganisms and plants. Thus, human ... ...

    Abstract Nickel (Ni) metal and Ni compounds are widely used in applications like stainless steel, alloys, and batteries. Nickel is a naturally occurring element in water, soil, air, and living organisms, and is essential to microorganisms and plants. Thus, human and environmental nickel exposures are ubiquitous. Production and use of nickel and its compounds can, however, result in additional exposures to humans and the environment. Notable human health toxicity effects identified from human and/or animal studies include respiratory cancer, non-cancer toxicity effects following inhalation, dermatitis, and reproductive effects. These effects have thresholds, with indirect genotoxic and epigenetic events underlying the threshold mode of action for nickel carcinogenicity. Differences in human toxicity potencies/potentials of different nickel chemical forms are correlated with the bioavailability of the Ni 2+ ion at target sites. Likewise, Ni 2+ has been demonstrated to be the toxic chemical species in the environment, and models have been developed that account for the influence of abiotic factors on the bioavailability and toxicity of Ni 2+ in different habitats. Emerging issues regarding the toxicity of nickel nanoforms and metal mixtures are briefly discussed. This review is unique in its covering of both human and environmental nickel toxicity data.
    Keywords nickel ; bioavailability ; carcinogenicity ; genotoxicity ; allergy ; reproductive ; asthma ; nanoparticles ; ecotoxicity ; environment ; Inorganic chemistry ; QD146-197
    Subject code 333
    Language English
    Publishing date 2019-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  3. Article ; Online: The impact of cash transfers on mental health in children and young people in low-income and middle-income countries

    Crick Lund / Alicia Matijasevich / David McDaid / Ricardo Araya / Philipp Hessel / Annie Zimmerman / Emily Garman / Mauricio Avendano-Pabon / Sara Evans-Lacko / A-La Park / Yadira Diaz / Carola Ziebold / Annette Bauer / Cristiane Silvestre Paula

    BMJ Global Health, Vol 6, Iss

    a systematic review and meta-analysis

    2021  Volume 4

    Abstract: Introduction Although cash transfer programmes are not explicitly designed to improve mental health, by reducing poverty and improving the life chances of children and young people, they may also improve their mental health. This systematic review and ... ...

    Abstract Introduction Although cash transfer programmes are not explicitly designed to improve mental health, by reducing poverty and improving the life chances of children and young people, they may also improve their mental health. This systematic review and meta-analysis assessed the evidence on the effectiveness of cash transfers to improve the mental health of children and young people in low-income and middle-income countries.Methods We searched Pubmed, EBSCOhost, Scientific Electronic Library Online, ISI Web of Science and Social Sciences Citation Index and grey literature (from January 2000 to July 2020) for studies which quantitatively assessed the impact of cash transfers on mental health in young people (aged 0–24 years), using a design that incorporated a control group. We extracted Cohen’s d effects size and used a random-effects model for the meta-analysis on studies that measured depressive symptoms, I2 statistic and assessment of study quality.Results We identified 12 116 articles for screening, of which 12 were included in the systematic review (covering 13 interventions) and seven in the meta-analysis assessing impact on depressive symptoms specifically. There was high heterogeneity (I2=95.2) and a high risk of bias (0.38, 95% CIs: −5.08 to 5.85; p=0.86) across studies. Eleven interventions (85%) showed a significant positive impact of cash transfers on at least one mental health outcome in children and young people. However, no study found a positive effect on all mental health outcomes examined, and the meta-analysis showed no impact of cash transfers on depressive symptoms (0.02, 95% CIs: −0.19 to 0.23; p=0.85).Conclusion Cash transfers may have positive effects on some mental health outcomes for young people, with no negative effects identified. However, there is high heterogeneity across studies, with some interventions showing no effects. Our review highlights how the effect of cash transfers may vary by social and economic context, culture, design, conditionality and mental health outcome.
    Keywords Medicine (General) ; R5-920 ; Infectious and parasitic diseases ; RC109-216
    Subject code 306 ; 360
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Strengthening self-regulation and reducing poverty to prevent adolescent depression and anxiety

    Crick Lund / Mark J. D. Jordans / Emily Garman / Ricardo Araya / Mauricio Avendano / Annette Bauer / Vikram Bahure / Tarun Dua / Georgia Eleftheriou / Sara Evans-Lacko / Juan Felipe García Rodríguez / Kamal Gautam / Martin Gevonden / Philipp Hessel / Brandon A. Kohrt / Lydia Krabbendam / Nagendra P. Luitel / Sanchari Roy / Manuel Seifert Bonifaz /
    Rakesh Singh / Mohammadamin Sinichi / Katherine Sorsdahl / Graham Thornicroft / Wietse A. Tol / Daniela Trujillo / Nicci van der Merwe / Syed Shabab Wahid / Paula Yarrow

    Epidemiology and Psychiatric Sciences, Vol

    Rationale, approach and methods of the ALIVE interdisciplinary research collaboration in Colombia, Nepal and South Africa

    2023  Volume 32

    Abstract: Abstract Aims Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent ... ...

    Abstract Abstract Aims Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent adolescent depression and anxiety in low- and middle-income countries (LMICs), where 90% of adolescents live. This article introduces the ‘Improving Adolescent mentaL health by reducing the Impact of poVErty (ALIVE)’ study, its conceptual framework, objectives, methods and expected outcomes. The aim of the ALIVE study is to develop and pilot-test an intervention that combines poverty reduction with strengthening self-regulation to prevent depression and anxiety among adolescents living in urban poverty in Colombia, Nepal and South Africa. Methods This aim will be achieved by addressing four objectives: (1) develop a conceptual framework that identifies the causal mechanisms linking poverty, self-regulation and depression and anxiety; (2) develop a multi-component selective prevention intervention targeting self-regulation and poverty among adolescents at high risk of developing depression or anxiety; (3) adapt and validate instruments to measure incidence of depression and anxiety, mediators and implementation parameters of the prevention intervention; and (4) undertake a four-arm pilot cluster randomised controlled trial to assess the feasibility, acceptability and cost of the selective prevention intervention in the three study sites. Results The contributions of this study include the active engagement and participation of adolescents in the research process; a focus on the causal mechanisms of the intervention; building an evidence base for prevention interventions in LMICs; and the use of an interdisciplinary approach. Conclusions By developing and evaluating an intervention that addresses multidimensional poverty and self-regulation, ALIVE can make contributions to evidence on the integration of mental health into broader development policy and practice.
    Keywords Adolescence ; anxiety ; depression ; poverty ; prevention ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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