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  1. Article ; Online: The medial tangent of the proximal tibia is a suitable extra-articular landmark in determining the tibial anteroposterior axis.

    Lee, Hyunho / Sumino, Takanobu / Suzuki, Takashi / Sano, Yutaka / Endo, Noriyuki / Chang, Yingshih / Fujimaki, Hirohisa / Ryu, Keinosuke / Nakanishi, Kazuyoshi

    BMC musculoskeletal disorders

    2021  Volume 22, Issue 1, Page(s) 346

    Abstract: Background: Tibial rotational alignment in total knee arthroplasty (TKA) is generally determined based on intra-articular structure, and can be difficult to ascertain in some cases. The aim of this study was to investigate whether the medial tangent ... ...

    Abstract Background: Tibial rotational alignment in total knee arthroplasty (TKA) is generally determined based on intra-articular structure, and can be difficult to ascertain in some cases. The aim of this study was to investigate whether the medial tangent angle of the tibia (MTAT) could be useful in determining the anteroposterior axis of the tibia.
    Methods: This study was performed on 103 lower limbs in 53 patients who underwent primary total hip arthroplasty. The selection criteria for our study were based on the assumption that knees in patients undergoing THA exhibit fewer degenerative changes than knees in patients undergoing TKA. Using computed tomography images, the MTAT, comprising the medial tangent of the proximal tibia and the anteroposterior (AP) axis of the tibia, was measured on three horizontal planes: at the distal edge of the tibial tubercle (A), at 5 cm distally (B), and at 10 cm further distally (C). The tibial medial surface was grouped into three classes according to shape: valley type, flat type, and hill type. The percentage at which these shapes were observed in each group was also calculated. Measurement reliability was calculated using the intraclass correlation coefficient.
    Results: The angles were 45.2° (interquartile range: IR 43.0-47.7) at A, 42.7° (IR 38.7-45.9) at B, and 42.4° (IR 38.2-45.9) at C. Intra-rater reliability and inter-rater reliability was 0.982 and 0.974 at A, 0.810 and 0.411 at B, and 0.940 and 0.811 at C, respectively. Regarding the tibial medial surface, the valley type was observed in all cases at A, and the hill type was observed in the highest percentage of cases at B and C.
    Conclusions: The MTAT was approximately 45° at level A, and reproducibility was the highest among the three groups. The two points forming the valley on the tibial medial surface were bony ridges. Therefore, the medial tangent of the tibia at level A could be easily determined. Because the distal edge of the tibial tubercle exists at the surgical area and the extra-articular area, it can be a suitable intraoperative, extra-articular landmark in determining the tibial AP axis, even for revision TKA.
    MeSH term(s) Humans ; Knee Joint/diagnostic imaging ; Knee Joint/surgery ; Osteoarthritis, Knee ; Reproducibility of Results ; Rotation ; Tibia/diagnostic imaging ; Tibia/surgery
    Language English
    Publishing date 2021-04-12
    Publishing country England
    Document type Journal Article
    ISSN 1471-2474
    ISSN (online) 1471-2474
    DOI 10.1186/s12891-021-04206-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Total Synthesis of Sarcophytonolide H and Isosarcophytonolide D: Structural Revision of Isosarcophytonolide D and Structure-Antifouling Activity Relationship of Sarcophytonolide H.

    Takamura, Hiroyoshi / Kikuchi, Takahiro / Endo, Noriyuki / Fukuda, Yuji / Kadota, Isao

    Organic letters

    2016  Volume 18, Issue 9, Page(s) 2110–2113

    Abstract: The first total syntheses of sarcophytonolide H and the originally proposed and correct structures of isosarcophytonolide D have been achieved via transannular ring-closing metathesis (RCM). These total syntheses culminated in the stereostructural ... ...

    Abstract The first total syntheses of sarcophytonolide H and the originally proposed and correct structures of isosarcophytonolide D have been achieved via transannular ring-closing metathesis (RCM). These total syntheses culminated in the stereostructural confirmation of sarcophytonolide H and the reassignment of isosarcophytonolide D, respectively. The antifouling activity of the synthetic sarcophytonolide H and its analogues was also evaluated.
    Language English
    Publishing date 2016-05-06
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.6b00737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Late-stage divergent synthesis and antifouling activity of geraniol-butenolide hybrid molecules.

    Takamura, Hiroyoshi / Ohashi, Takumi / Kikuchi, Takahiro / Endo, Noriyuki / Fukuda, Yuji / Kadota, Isao

    Organic & biomolecular chemistry

    2017  Volume 15, Issue 26, Page(s) 5549–5555

    Abstract: Hybrid molecules consisting of geraniol and butenolide were designed and synthesized by the late-stage divergent strategy. In the synthetic route, ring-closing metathesis was utilized for the construction of a butenolide moiety. A biological evaluation ... ...

    Abstract Hybrid molecules consisting of geraniol and butenolide were designed and synthesized by the late-stage divergent strategy. In the synthetic route, ring-closing metathesis was utilized for the construction of a butenolide moiety. A biological evaluation of the eight synthetic hybrid compounds revealed that these molecules exhibit antifouling activity against the cypris larvae of the barnacle Balanus (Amphibalanus) amphitrite with EC
    Language English
    Publishing date 2017-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/c7ob01160a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Total Synthesis of Sarcophytonolide H and Isosarcophytonolide D: Structural Revision of Isosarcophytonolide D and Structure–Antifouling Activity Relationship of Sarcophytonolide H

    Takamura, Hiroyoshi / Kikuchi Takahiro / Endo Noriyuki / Fukuda Yuji / Kadota Isao

    Organic letters. 2016 May 06, v. 18, no. 9

    2016  

    Abstract: The first total syntheses of sarcophytonolide H and the originally proposed and correct structures of isosarcophytonolide D have been achieved via transannular ring-closing metathesis (RCM). These total syntheses culminated in the stereostructural ... ...

    Abstract The first total syntheses of sarcophytonolide H and the originally proposed and correct structures of isosarcophytonolide D have been achieved via transannular ring-closing metathesis (RCM). These total syntheses culminated in the stereostructural confirmation of sarcophytonolide H and the reassignment of isosarcophytonolide D, respectively. The antifouling activity of the synthetic sarcophytonolide H and its analogues was also evaluated.
    Keywords antifouling activities ; chemical reactions ; chemical structure ; organic compounds
    Language English
    Dates of publication 2016-0506
    Size p. 2110-2113.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1523-7052
    DOI 10.1021%2Facs.orglett.6b00737
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Purification and partial amino acid sequence analysis of the larval settlement-inducing pheromone from adult extracts of the barnacle, Balanus amphitrite (=Amphibalanus amphitrite).

    Endo, Noriyuki / Nogata, Yasuyuki / Yoshimura, Erina / Matsumura, Kiyotaka

    Biofouling

    2009  Volume 25, Issue 5, Page(s) 429–434

    Abstract: A previously undescribed larval settlement-inducing protein was purified from adult extracts of the barnacle, Balanus amphitrite (=Amphibalanus amphitrite). Results of SDS-PAGE indicated that the relative molecular mass of the protein in reduced and ... ...

    Abstract A previously undescribed larval settlement-inducing protein was purified from adult extracts of the barnacle, Balanus amphitrite (=Amphibalanus amphitrite). Results of SDS-PAGE indicated that the relative molecular mass of the protein in reduced and denatured form is 31,600 +/- 500 kDa, and that it is distinct from the Settlement Inducing Protein Complex (SIPC) which has previously been determined as a larval settlement-inducing pheromone. The N-terminal 33-residue sequence of the intact protein showed no similarity with previously reported proteins in the EMBL/Genbank/DDBJ databases. The purified protein at a concentration of 10 microg ml(-1) induced approximately four times more larval settlement than the control (filtered natural seawater). In addition, results of the assay using both 24-well polystyrene plates and agarose gels indicated that this protein is probably released into seawater and attracts cypris larvae. These results suggest that the purified protein is a waterborne type pheromone which induces settlement of larvae of B. amphitrite.
    MeSH term(s) Amino Acid Sequence ; Animals ; Behavior, Animal ; Electrophoresis, Polyacrylamide Gel ; Larva/growth & development ; Molecular Sequence Data ; Molecular Weight ; Pheromones/chemistry ; Pheromones/isolation & purification ; Thoracica/growth & development ; Thoracica/metabolism
    Chemical Substances Pheromones
    Language English
    Publishing date 2009
    Publishing country England
    Document type Journal Article
    ISSN 1029-2454
    ISSN (online) 1029-2454
    DOI 10.1080/08927010902875113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: cDNA cloning and primary structure comparison of tauropine dehydrogenase and β-alanopine dehydrogenase from the limpet Cellana grata

    Endo, Noriyuki / Matsu-ura, Hiroto / Kan-no, Nobuhiro

    Fisheries science. 2009 Nov., v. 75, no. 6

    2009  

    Abstract: The primary structures of β-alanopine dehydrogenase (β-AlDH) and tauropine dehydrogenase (TaDH) from the limpet Cellana grata were determined by amino acid sequence analysis and complementary DNA (cDNA) cloning. β-AlDH and TaDH cDNAs comprised 1,479 ... ...

    Abstract The primary structures of β-alanopine dehydrogenase (β-AlDH) and tauropine dehydrogenase (TaDH) from the limpet Cellana grata were determined by amino acid sequence analysis and complementary DNA (cDNA) cloning. β-AlDH and TaDH cDNAs comprised 1,479 nucleotides and 1,444 nucleotides, respectively, and both included an open reading frame of 1,206 nucleotides corresponding to 402 amino acids. The enzymes showed very high homology, with 96% amino acid identity. These enzymes were homologous to other marine invertebrate opine dehydrogenases (OpDHs), except TaDH of the marine sponge Halichondria japonica. The highest homologies were to alanopine dehydrogenase from Fusitriton oregonensis, being 57% for both enzymes. A phylogenetic tree constructed on the basis of marine invertebrate OpDHs and developed using a sequence distance method and neighbor-joining algorithm showed a tendency for the classification of animals from taxonomically derived evolutionary trees. Additionally, Cellana grata OpDHs belong to the same group as the Gastropoda OpDHs. This represents the first report concerning the primary structure of marine invertebrate β-AlDH, and primary structure comparisons of clearly different enzymes from the same species.
    Keywords Gastropoda ; Porifera ; algorithms ; amino acid sequences ; amino acids ; complementary DNA ; limpets ; nucleotides ; oxidoreductases ; phylogeny ; sequence analysis
    Language English
    Dates of publication 2009-11
    Size p. 1471-1479.
    Publishing place Springer Japan
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1192654-5
    ISSN 1444-2906 ; 0919-9268
    ISSN (online) 1444-2906
    ISSN 0919-9268
    DOI 10.1007/s12562-009-0178-x
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Invasion, dispersion, population persistence and ecological impacts of a freshwater mussel (Limnoperna fortunei) in the Honshu Island of Japan

    Nakano, Daisuke / Baba, Takashi / Endo, Noriyuki / Nagayama, Shigeya / Fujinaga, Ai / Uchida, Asako / Shiragane, Akiko / Urabe, Misako / Kobayashi, Takuya

    Biological invasions. 2015 Feb., v. 17, no. 2

    2015  

    Abstract: The freshwater mussels Limnoperna and Dreissena require the low advective flow conditions of large continental rivers so their larvae can develop sufficiently to settle before reaching the ocean in order to maintain their populations. However, these ... ...

    Abstract The freshwater mussels Limnoperna and Dreissena require the low advective flow conditions of large continental rivers so their larvae can develop sufficiently to settle before reaching the ocean in order to maintain their populations. However, these species have also invaded some island rivers with high advective flows. We integrated data for the invasion, distribution, genetic composition and ecological impacts of L. fortunei on the Honshu Island of Japan. Invasion route and mechanisms of dispersion and population persistence are detailed in non-continental rivers. The initial invasion and several of the dispersions of L. fortunei were closely related to the food culture of consuming freshwater clams in Japan. Other dispersions were most likely affected by headrace channels. Thus, population persistence depends on anthropogenic lentic environments such as reservoirs and channel networks as a nursing habitat for L. fortunei larvae. L. fortunei was often abundant near artificial habitats and less abundant in the lower segments of rivers. We also contrast the invasion processes of freshwater mussels in continental and non-continental rivers.
    Keywords Dreissena ; clams ; dispersions ; environmental impact ; foodways ; freshwater ; habitats ; larvae ; lentic systems ; mussels ; rivers ; Japan
    Language English
    Dates of publication 2015-02
    Size p. 743-759.
    Publishing place Springer-Verlag
    Document type Article
    ZDB-ID 1438729-3
    ISSN 1573-1464 ; 1387-3547
    ISSN (online) 1573-1464
    ISSN 1387-3547
    DOI 10.1007/s10530-014-0765-3
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  8. Article: Purification, characterization, and cDNA cloning of opine dehydrogenases from the polychaete rockworm Marphysa sanguinea.

    Endo, Noriyuki / Kan-no, Nobuhiro / Nagahisa, Eizoh

    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

    2007  Volume 147, Issue 2, Page(s) 293–307

    Abstract: Alanopine dehydrogenase (AlDH) and three isoforms of strombine/alanopine dehydrogenase (St/AlDH) were purified from muscle tissue of the polychaete rockworm Marphysa sanguinea. The four enzymes, which can be distinguished by the isoelectric point, are ... ...

    Abstract Alanopine dehydrogenase (AlDH) and three isoforms of strombine/alanopine dehydrogenase (St/AlDH) were purified from muscle tissue of the polychaete rockworm Marphysa sanguinea. The four enzymes, which can be distinguished by the isoelectric point, are monomeric 42 kDa proteins, possess similar pH-activity profiles, and display specificity for pyruvate and NAD(H). The three isoforms of St/AlDH show equivalent Km and Vmax for glycine and L-alanine and for D-strombine and meso-alanopine. Free amino acid levels in the muscle and D-strombine accumulation in vivo during muscle activity suggest that St/AlDHs function physiologically as StDH. AlDH shows specificity for L-alanine and meso-alanopine, but not for glycine or D-strombine. The amino acid sequences of AlDH and one of the St/AlDH isoforms were determined by a combination of amino acid sequence analysis and cDNA cloning. St/AlDH cDNA consisted of 1586 bp nucleotides that encode a 399-residue protein (43,346.70 Da), and AlDH cDNA consisted of 1587 bp nucleotides that encode a 399-residue protein (43,886.68 Da). The two amino acid sequences deduced from the cDNA displayed 67% amino acid identity, with greatest similarity to that of tauropine dehydrogenase from the polychaete Arabella iricolor.
    MeSH term(s) Amino Acid Sequence ; Animals ; Base Sequence ; Cloning, Molecular ; DNA Primers ; DNA, Complementary/genetics ; Electrophoresis, Polyacrylamide Gel ; Isoenzymes/genetics ; Molecular Sequence Data ; Muscle, Skeletal/metabolism ; Oxidoreductases Acting on CH-NH Group Donors/genetics ; Polychaeta/enzymology ; Polychaeta/genetics ; Sequence Analysis, DNA ; Sequence Homology ; Species Specificity
    Chemical Substances DNA Primers ; DNA, Complementary ; Isoenzymes ; Oxidoreductases Acting on CH-NH Group Donors (EC 1.5.-) ; alanopine dehydrogenase (EC 1.5.1.-)
    Language English
    Publishing date 2007-06
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 121247-3
    ISSN 1879-1107 ; 1096-4959 ; 0305-0491
    ISSN (online) 1879-1107
    ISSN 1096-4959 ; 0305-0491
    DOI 10.1016/j.cbpb.2007.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Unified Total Synthesis, Stereostructural Elucidation, and Biological Evaluation of Sarcophytonolides.

    Takamura, Hiroyoshi / Kikuchi, Takahiro / Iwamoto, Kohei / Nakao, Eiji / Harada, Naoki / Otsu, Taichi / Endo, Noriyuki / Fukuda, Yuji / Ohno, Osamu / Suenaga, Kiyotake / Guo, Yue-Wei / Kadota, Isao

    The Journal of organic chemistry

    2018  Volume 83, Issue 18, Page(s) 11028–11056

    Abstract: Sarcophytonolides are cembranolide diterpenes isolated from the soft corals of genus Sarcophyton. Unified total synthesis of sarcophytonolides C, E, F, G, H, and J and isosarcophytonolide D was achieved. The synthetic routes feature NaHMDS- or ... ...

    Abstract Sarcophytonolides are cembranolide diterpenes isolated from the soft corals of genus Sarcophyton. Unified total synthesis of sarcophytonolides C, E, F, G, H, and J and isosarcophytonolide D was achieved. The synthetic routes feature NaHMDS- or SmI
    MeSH term(s) Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Chemistry Techniques, Synthetic ; Diterpenes/chemical synthesis ; Diterpenes/chemistry ; Diterpenes/pharmacology ; HL-60 Cells ; Humans ; Models, Molecular ; Molecular Conformation ; Stereoisomerism
    Chemical Substances Antineoplastic Agents ; Diterpenes
    Language English
    Publishing date 2018-08-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.8b01634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Species-specific detection and quantification of common barnacle larvae from the Japanese coast using quantitative real-time PCR.

    Endo, Noriyuki / Sato, Kana / Matsumura, Kiyotaka / Yoshimura, Erina / Odaka, Yukiko / Nogata, Yasuyuki

    Biofouling

    2010  Volume 26, Issue 8, Page(s) 901–911

    Abstract: Species-specific detection and quantification methods for barnacle larvae using quantitative real-time polymerase chain reaction (qPCR) were developed. Species-specific primers for qPCR were designed for 13 barnacle species in the mitochondrial 12S ... ...

    Abstract Species-specific detection and quantification methods for barnacle larvae using quantitative real-time polymerase chain reaction (qPCR) were developed. Species-specific primers for qPCR were designed for 13 barnacle species in the mitochondrial 12S ribosomal RNA gene region. Primer specificity was examined by PCR using template DNA extracted from each of the 13 barnacle species, other unidentified barnacle species, and field collected zooplankton samples. The resulting PCR products comprised single bands following agarose gel electrophoresis when the templates corresponded to primers. The amplifications were highly species-specific even for the field plankton samples. The field plankton samples were subjected to qPCR assay. The calculated DNA contents for each barnacle species were closely correlated with the number of larvae measured by microscopic examination. The method could be applied to quantify barnacle larvae in natural plankton samples.
    MeSH term(s) Animals ; Base Sequence ; Biofouling ; Classification/methods ; DNA Primers ; Japan ; Larva/classification ; Larva/genetics ; Molecular Sequence Data ; Oceans and Seas ; Polymerase Chain Reaction/methods ; RNA, Ribosomal/chemistry ; Sequence Alignment ; Sequence Analysis, RNA ; Species Specificity ; Thoracica/classification ; Thoracica/genetics ; Thoracica/growth & development
    Chemical Substances DNA Primers ; RNA, Ribosomal ; RNA, ribosomal, 12S
    Language English
    Publishing date 2010-11
    Publishing country England
    Document type Journal Article
    ISSN 1029-2454
    ISSN (online) 1029-2454
    DOI 10.1080/08927014.2010.531389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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