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  1. Article: Impact of Antecedent Aspirin Use on Infarct Size, Bleeding and Composite Endpoint in Patients with de Novo Acute Myocardial Infarction.

    Enhos, Asim / Karacop, Erdem

    Therapeutics and clinical risk management

    2021  Volume 17, Page(s) 441–452

    Abstract: Background: The study aimed to evaluate the impact of antecedent aspirin use on infarct size, bleeding and composite endpoint in patients with de novo acute myocardial infarction.: Patients and methods: A total of 562 consecutive patients with de ... ...

    Abstract Background: The study aimed to evaluate the impact of antecedent aspirin use on infarct size, bleeding and composite endpoint in patients with de novo acute myocardial infarction.
    Patients and methods: A total of 562 consecutive patients with de novo acute myocardial infarction were included in this prospective cohort study. Patients were assigned into two groups based on presence (n=212) and absence (n=350) of prior aspirin use. Primary endpoint was myocardial infarct size, as estimated by troponin I peak. In-hospital mortality, bleeding and composite clinical endpoint including cardiogenic shock, stroke, in-hospital mortality and major bleeding were also evaluated.
    Results: Although GRACE and CRUSADE scores were higher, troponin I peak was lower in prior aspirin users. This result was maintained after adjustment for baseline ischemic risk profile and other major confounders including MI type and location. Despite high CRUSADE score, there was no increase in major and minor bleeding. Minimal bleeding was higher in antecedent aspirin users. When it was adjusted for the CRUSADE score, a similar risk was reported.
    Conclusion: Patients with de novo acute myocardial infarction using aspirin for primary prevention have an unexpectedly smaller infarct size and similar bleeding rates.
    Language English
    Publishing date 2021-05-21
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186560-7
    ISSN 1178-203X ; 1176-6336
    ISSN (online) 1178-203X
    ISSN 1176-6336
    DOI 10.2147/TCRM.S307768
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  2. Article ; Online: Predictive role of ventricular repolarization parameters for the occurrence of complete heart block in patients undergoing transcatheter aortic valve implantation.

    Karacop, Erdem / Enhos, Asim

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

    2019  Volume 25, Issue 4, Page(s) e12734

    Abstract: Background: We investigated the role of ventricular repolarization parameters to predict complete atrioventricular block in patients undergoing transcatheter aortic valve implantation (TAVI).: Methods: A total of 150 patients undergoing TAVI due to ... ...

    Abstract Background: We investigated the role of ventricular repolarization parameters to predict complete atrioventricular block in patients undergoing transcatheter aortic valve implantation (TAVI).
    Methods: A total of 150 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned in two groups based on the presence (n: 49) or absence (n: 101) of complete atrioventricular block after TAVI. Ventricular repolarization intervals (QT, QTc, JT, JTc, TP-E), indices (QT dispersion), and ratios (TP-E/QT, TP-E/QTc, TP-E/JTc) were measured.
    Results: Electrocardiographic repolarization parameters such as Tp-e interval: 74.2 ± 5.1 versus 59.2 ± 6.1 ms, p < .001; QTc interval: 397.6 ± 3.4 versus 368.1 ± 7.8 ms, p < .001; JTc interval: 317.4 ± 11.3 versus 291.1 ± 6.7 ms, p < .001; Tp-e/QT ratio: 0.28 ± 0.04 versus 0.20 ± 0.04, p < .001; Tp-e/QTc ratio: 0.29 ± 0.04 versus 0.19 ± 0.03, p < .001; Tp-e/JT ratio: 0.32 ± 0.03 versus 0.23 ± 0.03, p < .001; Tp-e/JTc ratio: 0.30 ± 0.02 versus 0.2 ± 0.03, p < .001; and QT dispersion: 34.4 ± 3.0 versus 17.8 ± 3.6 ms, p < .01 were significantly higher in post-TAVI permanent pacemaker group. In a univariate regression analysis, pulmonary artery pressure, heart rate, coronary artery disease, Tp-e/QTc, Tp-e/JTc, and PR interval were significantly associated with complete heart block. Tp-e/JTc (OR 0.373, p = .067) and PR interval (OR 0.898, p = .079) were found to be independent predictors of these type of arrhythmias in a multivariate analysis. But it is not statistically significant.
    Conclusion: Our results suggest that repolarization parameters may play a role in predicting complete atrioventricular block. Tp-e/JTc was found to be potential independent risk marker for this setting.
    MeSH term(s) Aged, 80 and over ; Aortic Valve Stenosis/surgery ; Atrioventricular Block/diagnosis ; Atrioventricular Block/physiopathology ; Cohort Studies ; Electrocardiography/methods ; Female ; Heart Ventricles/physiopathology ; Humans ; Male ; Pacemaker, Artificial ; Predictive Value of Tests ; Retrospective Studies ; Transcatheter Aortic Valve Replacement/methods
    Language English
    Publishing date 2019-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1325530-7
    ISSN 1542-474X ; 1082-720X
    ISSN (online) 1542-474X
    ISSN 1082-720X
    DOI 10.1111/anec.12734
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  3. Article ; Online: Short-term azithromycin use is associated with QTc interval prolongation in children with cystic fibrosis.

    Enhoş, Asım / Doğuş Kus, Hazar / Yozgat, Can Yilmaz / Cakır, Erkan / Yazan, Hakan / Erol, Ahmet Berk / Erenberk, Ufuk / Yozgat, Yilmaz

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie

    2024  

    Abstract: Background: Azithromycin is used for children with cystic fibrosis (CF) for its immunomodulatory and anti-inflammatory action. This study investigated the short-term alterations in QTc interval associated with azithromycin prophylaxis in pediatric ... ...

    Abstract Background: Azithromycin is used for children with cystic fibrosis (CF) for its immunomodulatory and anti-inflammatory action. This study investigated the short-term alterations in QTc interval associated with azithromycin prophylaxis in pediatric patients with CF.
    Methods: This study included 121 patients with mild CF, of whom 76 received azithromycin (patient group) and 45 did not receive azithromycin (control group). The patient and control groups were categorized according to age as under 12 years of age and over 12 years of age. The first presentation measured all the patient and control groups at basic QTc time intervals. The QTc intervals of all patients were then remeasured systemically at 1, 3, and 6 months. Age categories and QTc intervals that were calculated at each month in the patient and control groups were compared statistically.
    Results: A statistically significant difference was detected in the patient group between the initial QTc interval time and the electrocardiogram (ECG) findings in the first and third months after prophylaxis treatment (p < 0.001; p = 0.01). However, no statistically significant difference was detected in the sixth month (p > 0.05) in all groups. Almost all of the children's QTc intervals were within normal range and within the safety zone (under 0.44 s). No statistically significant difference was detected in the control group between the initial ECG and the QTc intervals measured at 1, 3, and 6 months.
    Conclusion: Short-term use of azithromycin prophylaxis in pediatric patients with mild CF slightly increased the QTc interval in the first and third months of follow-up. Nevertheless, all QTc interval changes fell within the safety zone. Notably, 1 month of follow-up treatment should be performed to check for any alteration in the QTc interval. If increased QTc interval duration is not detected in the first month, azithromycin prophylaxis can be safely prescribed.
    Language English
    Publishing date 2024-04-17
    Publishing country France
    Document type Journal Article
    ZDB-ID 1181947-9
    ISSN 1769-664X ; 0929-693X
    ISSN (online) 1769-664X
    ISSN 0929-693X
    DOI 10.1016/j.arcped.2024.02.004
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  4. Article ; Online: The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients.

    Bakhshaliyev, Nijad / Uluganyan, Mahmut / Enhos, Asim / Karacop, Erdem / Ozdemir, Ramazan

    Journal of electrocardiology

    2020  Volume 62, Page(s) 59–64

    Abstract: Background: The combination of Hydroxychloroquine (HCQ) and azithromycin showed effectiveness as a treatment for COVID-19 and is being used widely all around the world. Despite that those drugs are known to cause prolonged QT interval individually there ...

    Abstract Background: The combination of Hydroxychloroquine (HCQ) and azithromycin showed effectiveness as a treatment for COVID-19 and is being used widely all around the world. Despite that those drugs are known to cause prolonged QT interval individually there is no study assessing the impact of this combination on electrocardiography (ECG). This study aimed to assess the impact of a 5-day course of HCQ and azithromycin combination on ECG in non-ICU COVID19(+) patients.
    Methods: In this retrospective observational study, we enrolled 109 COVID19(+) patients who required non-ICU hospitalization. All patients received 5-day protocol of HCQ and azithromycin combination. On-treatment ECGs were repeated 3-6 h after the second HCQ loading dose and 48-72 h after the first dose of the combination. ECGs were assessed in terms of rhythm, PR interval, QRS duration, QT and QTc intervals. Baseline and on-treatment ECG findings were compared. Demographic characteristics, laboratory results were recorded. Daily phone call-visit or bed-side visit were performed by attending physician.
    Results: Of the 109 patients included in the study, the mean age was 57.3 ± 14.4 years and 48 (44%) were male. Mean baseline PR interval was 158.47 ± 25.10 ms, QRS duration was 94.00 ± 20.55 ms, QTc interval was 435.28 ± 32.78 ms, 415.67 ± 28.51, 412.07 ± 25.65 according to Bazett's, Fridericia's and Framingham Heart Study formulas respectively. ∆PR was -2.94 ± 19.93 ms (p = .55), ∆QRS duration was 5.18 ± 8.94 ms (p = .03). ∆QTc interval was 6.64 ± 9.60 ms (p = .5), 10.67 ± 9.9 ms (p = .19), 14.14 ± 9.68 ms (p = .16) according to Bazett's, Fridericia's and Framingham Heart Study formulas respectively. There were no statistically significant differences between QTc intervals. No ventricular tachycardia, ventricular fibrillation or significant conduction delay was seen during follow-up. There was no death or worsening heart function.
    Conclusion: The 5-day course of HCQ- AZM combination did not lead to clinically significant QT prolongation and other conduction delays compared to baseline ECG in non-ICU COVID19(+) patients.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Azithromycin/administration & dosage ; Drug Therapy, Combination ; Electrocardiography ; Enzyme Inhibitors/administration & dosage ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Long QT Syndrome/chemically induced ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances Anti-Bacterial Agents ; Enzyme Inhibitors ; Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
    Keywords covid19
    Language English
    Publishing date 2020-08-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2020.08.008
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  5. Article ; Online: Impact of atrial flow regulator (AFR) implantation on 12-month mortality in heart failure : Insights from a single site in the PRELIEVE study.

    Bakhshaliyev, Nijad / Çelikkale, İlke / Enhoş, Asım / Karaçöp, Erdem / Uluganyan, Mahmut / Özdemir, Ramazan

    Herz

    2021  Volume 47, Issue 4, Page(s) 366–373

    Abstract: Background: Implantation of the atrial flow regulator (AFR) to create an interatrial left-to-right shunt has been shown to be safe and feasible to reduce intracardiac filling pressures in patients with heart failure (HF).: Objectives: We aimed to ... ...

    Title translation Auswirkung der Implantation eines Atrial Flow Regulator (AFR) auf die 12-Monats-Sterblichkeit bei Herzinsuffizienz : Erkenntnisse aus einem Zentrum im Rahmen der PRELIEVE-Studie.
    Abstract Background: Implantation of the atrial flow regulator (AFR) to create an interatrial left-to-right shunt has been shown to be safe and feasible to reduce intracardiac filling pressures in patients with heart failure (HF).
    Objectives: We aimed to assess the effect of AFR implantation on 12-month mortality and hospitalization rates in patients with reduced (HFrEF) or preserved HF (HFpEF).
    Methods: One-year follow-up data from 34 subjects enrolled at a single PRELIEVE center were analyzed. The 12-month predicted mortality was calculated using the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score. Patients were divided into two groups, according to their history of hospitalizations for HF.
    Results: Study data of 34 patients (HFrEF: 24 [70.6%]; HFpEF: 10 [29.4%]) were assessed. Median follow-up duration was 355 days. In total, 14 (41.2%) patients were hospitalized during the follow-up period and 6 (17.6%) of these patients were hospitalization for HF (HHF). A total of 24 hospitalizations occurred in this period and 8 (33%) hospitalizations were for HHF. The median baseline MAGGIC score was 23 and the median predicted mortality was 13.4/100 patient years. Observed mortality was 3.1/100 patient years. The observed survival (97%) was 10.3% (95% confidence interval 3.6-17.5%, p = 0.004) better than the predicted survival (86.6%).
    Conclusion: Our results suggest that AFR implantation has favorable effects on mortality in patients with heart failure, regardless of ejection fraction. Furthermore, compared to baseline, left ventricular filling pressure (assessed by echocardiography) decreased significantly without right side volume overload at the 1‑year follow-up.
    MeSH term(s) Echocardiography ; Heart Atria ; Heart Failure ; Humans ; Prognosis ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2021-08-30
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 8262-4
    ISSN 1615-6692 ; 0340-9937 ; 0946-1299
    ISSN (online) 1615-6692
    ISSN 0340-9937 ; 0946-1299
    DOI 10.1007/s00059-021-05063-w
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  6. Article: The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients

    Bakhshaliyev, Nijad / Uluganyan, Mahmut / Enhos, Asim / Karacop, Erdem / Ozdemir, Ramazan

    J Electrocardiol

    Abstract: BACKGROUND: The combination of Hydroxychloroquine (HCQ) and azithromycin showed effectiveness as a treatment for COVID-19 and is being used widely all around the world. Despite that those drugs are known to cause prolonged QT interval individually there ... ...

    Abstract BACKGROUND: The combination of Hydroxychloroquine (HCQ) and azithromycin showed effectiveness as a treatment for COVID-19 and is being used widely all around the world. Despite that those drugs are known to cause prolonged QT interval individually there is no study assessing the impact of this combination on electrocardiography (ECG). This study aimed to assess the impact of a 5-day course of HCQ and azithromycin combination on ECG in non-ICU COVID19(+) patients. METHODS: In this retrospective observational study, we enrolled 109 COVID19(+) patients who required non-ICU hospitalization. All patients received 5-day protocol of HCQ and azithromycin combination. On-treatment ECGs were repeated 3-6 h after the second HCQ loading dose and 48-72 h after the first dose of the combination. ECGs were assessed in terms of rhythm, PR interval, QRS duration, QT and QTc intervals. Baseline and on-treatment ECG findings were compared. Demographic characteristics, laboratory results were recorded. Daily phone call-visit or bed-side visit were performed by attending physician. RESULTS: Of the 109 patients included in the study, the mean age was 57.3 ± 14.4 years and 48 (44%) were male. Mean baseline PR interval was 158.47 ± 25.10 ms, QRS duration was 94.00 ± 20.55 ms, QTc interval was 435.28 ± 32.78 ms, 415.67 ± 28.51, 412.07 ± 25.65 according to Bazett's, Fridericia's and Framingham Heart Study formulas respectively. ∆PR was -2.94 ± 19.93 ms (p = .55), ∆QRS duration was 5.18 ± 8.94 ms (p = .03). ∆QTc interval was 6.64 ± 9.60 ms (p = .5), 10.67 ± 9.9 ms (p = .19), 14.14 ± 9.68 ms (p = .16) according to Bazett's, Fridericia's and Framingham Heart Study formulas respectively. There were no statistically significant differences between QTc intervals. No ventricular tachycardia, ventricular fibrillation or significant conduction delay was seen during follow-up. There was no death or worsening heart function. CONCLUSION: The 5-day course of HCQ- AZM combination did not lead to clinically significant QT prolongation and other conduction delays compared to baseline ECG in non-ICU COVID19(+) patients.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #703993
    Database COVID19

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  7. Article ; Online: The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients

    Bakhshaliyev, Nijad / Uluganyan, Mahmut / Enhos, Asim / Karacop, Erdem / Ozdemir, Ramazan

    Journal of Electrocardiology

    2020  Volume 62, Page(s) 59–64

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2020.08.008
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  8. Article ; Online: Assessment of the Relationship between Monocyte to High-Density Lipoprotein Ratio and Myocardial Bridge.

    Enhos, Asim / Cosansu, Kahraman / Huyut, Mustafa Ahmet / Turna, Fahrettin / Karacop, Erdem / Bakshaliyev, Nijad / Nadir, Aydin / Ozdemir, Ramazan / Uluganyan, Mahmut

    Arquivos brasileiros de cardiologia

    2018  Volume 112, Issue 1, Page(s) 12–17

    Abstract: Background: Assessing the monocyte to high-density lipoprotein ratio (MHR) is a new tool for predicting inflamation, which plays a major role in atherosclerosis. Myocardial bridge (MB) is thought to be a benign condition with development of ... ...

    Abstract Background: Assessing the monocyte to high-density lipoprotein ratio (MHR) is a new tool for predicting inflamation, which plays a major role in atherosclerosis. Myocardial bridge (MB) is thought to be a benign condition with development of atherosclerosis, particularly at the proximal segment of the brigde.
    Objective: To evaluate the relationhip between MHR and the presence of MB.
    Methods: We consecutively scanned patients referred for coronary angiography between January 2013- December 2016, and a total of 160 patients who had a MB and normal coronary artery were enrolled in the study. The patients' angiographic, demographic and clinic characteristics of the patients were reviewed from medical records. Monocytes and HDL-cholesterols were measured via complete blood count. MHR was calculated as the ratio of the absolute monocyte count to the HDL-cholesterol value. MHR values were divided into three tertiles as follows: lower (8.25 ± 1.61), moderate (13.11 ± 1.46), and higher (21.21 ± 4.30) tertile. A p-value of < 0.05 was considered significant.
    Results: MHR was significantly higher in the MB group compared to the control group with normal coronary arteries. We found the frequency of MB (p = 0.002) to increase as the MHR tertiles rose. The Monocyte-HDL ratio with a cut-point of 13.35 had 59% sensitivity and 65.0% specificity (ROC area under curve: 0.687, 95% CI: 0.606-0.769, p < 0.001) in accurately predicting a MB diagnosis. In the multivariate analysis, MHR (p = 0.013) was found to be a significant independent predictor of the presence of MB, after adjusting for other risk factors.
    Conclusion: The present study revealed a significant correlation between MHR and MB.
    MeSH term(s) Adult ; Atherosclerosis/blood ; Blood Cell Count ; Case-Control Studies ; Cholesterol, LDL/blood ; Coronary Angiography ; Female ; Humans ; Lipoproteins, HDL/blood ; Male ; Middle Aged ; Monocytes ; Multivariate Analysis ; Myocardial Bridging/blood ; Myocardial Bridging/etiology ; Reference Values ; Regression Analysis ; Risk Factors ; Sensitivity and Specificity ; Statistics, Nonparametric
    Chemical Substances Cholesterol, LDL ; Lipoproteins, HDL
    Language Portuguese
    Publishing date 2018-12-17
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.5935/abc.20180253
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  9. Article: Relation of coronary collateral circulation with epicardial fat volume in patients with stable coronary artery disease.

    Enhos, Asım / Sahin, Irfan / Can, Mehmet Mustafa / Biter, Ibrahim / Dinckal, Mustafa Hakan / Serebruany, Victor

    Journal of geriatric cardiology : JGC

    2014  Volume 10, Issue 4, Page(s) 344–348

    Abstract: Objective: To investigated the relationship between epicardial fat volume (EFV) and coronary collateral circulation (CCC) in patients with stable coronary artery disease (CAD).: Methods: The study population consisted of 152 consecutive patients with ...

    Abstract Objective: To investigated the relationship between epicardial fat volume (EFV) and coronary collateral circulation (CCC) in patients with stable coronary artery disease (CAD).
    Methods: The study population consisted of 152 consecutive patients with CAD who underwent coronary angiography and were found to have at least 95% significiant lesion in at least one major coronary artery. EFV was assessed utilizing 64-multislice computed tomography. The patients were classifield into impaired CCC group (Group 1, Rentrop grades 0-1, n = 58), or adequate CCC (Group 2, Rentrop grades 2-3, n = 94).
    Results: The EFV values were significantly higher in paitients with adequate CCC than in those with impaired CCC. In multivariate logistic regression analysis, EFV (OR = 1.059; 95% CI: 1.035-1.085; P = 0.001); and presence of angina were independent predictors of adequate CCC. In receiver-operating characteristic curve analysis, the EFV value > 106.5 mL yielded an area under the curve value of 0.84, with the test sensitivity of 49.3%, and with 98.3% specifity.
    Conclusions: High EFV, and the presence of angina independently predict adequate CCC in patients with stable coronary artery disease. This association offers new diagnostic opportinities to assess collateral flow by conventional ultrasound techniques.
    Language English
    Publishing date 2014-01-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 2421391-3
    ISSN 1671-5411
    ISSN 1671-5411
    DOI 10.3969/j.issn.1671-5411.2013.04.006
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  10. Article ; Online: The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation.

    Ay, Nuray Kahraman / Enhos, Asim / Ay, Yasin / Bakhshaliyev, Nijad / Nadir, Aydin / Karacop, Erdem / Celikkale, Ilke / Uluganyan, Mahmut / Ozdemir, Razaman / Goktekin, Omer

    Journal of electrocardiology

    2018  Volume 51, Issue 6, Page(s) 923–927

    Abstract: Background: Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to ... ...

    Abstract Background: Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis.
    Methods: A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated.
    Results: In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29-7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07-6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05-5.60, p: 0.03) emerged as significant independent predictors of short survival.
    Conclusion: Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.
    MeSH term(s) Aged ; Aged, 80 and over ; Aortic Valve Stenosis/mortality ; Aortic Valve Stenosis/surgery ; Atrial Fibrillation/mortality ; Atrial Fibrillation/physiopathology ; Comorbidity ; Echocardiography ; Electrocardiography ; Female ; Hospital Mortality ; Humans ; Male ; Prognosis ; Retrospective Studies ; Survival Rate ; Transcatheter Aortic Valve Replacement ; Ventricular Dysfunction, Left/mortality ; Ventricular Dysfunction, Left/physiopathology
    Language English
    Publishing date 2018-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2018.07.015
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