LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE

    Avilash K. Cramer / Deborah Plana / Helen Yang / Mary M. Carmack / Enze Tian / Michael S. Sinha / David Krikorian / David Turner / Jinhan Mo / Ju Li / Rajiv Gupta / Heather Manning / Florence T. Bourgeois / Sherry H. Yu / Peter K. Sorger / Nicole R. LeBoeuf

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 10

    Abstract: Abstract The COVID-19 pandemic has led to widespread shortages of personal protective equipment (PPE) for healthcare workers, including of N95 masks (filtering facepiece respirators; FFRs). These masks are intended for single use but their sterilization ... ...

    Abstract Abstract The COVID-19 pandemic has led to widespread shortages of personal protective equipment (PPE) for healthcare workers, including of N95 masks (filtering facepiece respirators; FFRs). These masks are intended for single use but their sterilization and subsequent reuse has the potential to substantially mitigate shortages. Here we investigate PPE sterilization using ionized hydrogen peroxide (iHP), generated by SteraMist equipment (TOMI; Frederick, MD), in a sealed environment chamber. The efficacy of sterilization by iHP was assessed using bacterial spores in biological indicator assemblies. After one or more iHP treatments, five models of N95 masks from three manufacturers were assessed for retention of function based on their ability to form an airtight seal (measured using a quantitative fit test) and filter aerosolized particles. Filtration testing was performed at a university lab and at a National Institute for Occupational Safety and Health (NIOSH) pre-certification laboratory. The data demonstrate that N95 masks sterilized using SteraMist iHP technology retain filtration efficiency up to ten cycles, the maximum number tested to date. A typical iHP environment chamber with a volume of ~ 80 m3 can treat ~ 7000 masks and other items (e.g. other PPE, iPADs), making this an effective approach for a busy medical center.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Analysis of SteraMist ionized hydrogen peroxide technology as a method for sterilizing N95 respirators and other personal protective equipment

    Avilash Cramer / Deborah Plana / Helen L Yang / Mary Carmack / Enze Tian / Michael S Sinha / David Krikorian / David Turner / Jinhan Mo / Ju Li / Rajiv Gupta / Heather Manning / Florence T. Bourgeois / Sherry H Yu / Peter Sorger / Nicole L LeBoeuf

    Abstract: The COVID-19 pandemic has led to widespread shortages of personal protective equipment (PPE) for healthcare workers, including filtering facepiece respirators (FFRs) such as N95 masks. These masks are normally intended for single use, but their ... ...

    Abstract The COVID-19 pandemic has led to widespread shortages of personal protective equipment (PPE) for healthcare workers, including filtering facepiece respirators (FFRs) such as N95 masks. These masks are normally intended for single use, but their sterilization and subsequent reuse could substantially mitigate a world-wide shortage. In this study, we investigate PPE sterilization using ionized hydrogen peroxide (iHP), generated by SteraMist® equipment (TOMI; Frederick, MD), in a sealed environment chamber installed in the animal facility of an academic medical center. Following one to five sterilization cycles, five N95 mask models from three manufacturers were evaluated using three criteria: efficiency of iHP in sterilization (measured with bacterial spores in standard biological indicator assemblies), ability of sterilized masks to efficiently filter particles down to 0.3μm, and a quantitative fit test. Filtration efficiency was measured using ambient particulate matter at a university lab and an aerosolized NaCl challenge at a National Institute for Occupational Safety and Health (NIOSH) pre-certification laboratory. The data demonstrate that N95 masks sterilized using SteraMist iHP technology retain function up to five cycles, the maximum number tested. Some but not all PPE could also be sterilized in the same manner, and pre-treatment with a handheld iHP generator was required for semi-enclosed surfaces such as respirator hoses. A typical environment chamber with a volume of ~80 m3 can treat ~7000 masks per day, and as well as other items of PPE, making this an effective approach for a busy medical center.
    Keywords covid19
    Publisher medrxiv
    Document type Article ; Online
    DOI 10.1101/2020.04.19.20069997
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic.

    Davis T Weaver / Benjamin D McElvany / Vishhvaan Gopalakrishnan / Kyle J Card / Dena Crozier / Andrew Dhawan / Mina N Dinh / Emily Dolson / Nathan Farrokhian / Masahiro Hitomi / Emily Ho / Tanush Jagdish / Eshan S King / Jennifer L Cadnum / Curtis J Donskey / Nikhil Krishnan / Gleb Kuzmin / Ju Li / Jeff Maltas /
    Jinhan Mo / Julia Pelesko / Jessica A Scarborough / Geoff Sedor / Enze Tian / Gary C An / Sean A Diehl / Jacob G Scott

    PLoS ONE, Vol 16, Iss 7, p e

    2021  Volume 0241734

    Abstract: Personal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in the ... ...

    Abstract Personal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in the United States and many parts of the world, healthcare provider demand for these necessities is currently outpacing supply. In the midst of the current pandemic, there has been a concerted effort to identify viable ways to conserve PPE, including decontamination after use. In this study, we outline a procedure by which PPE may be decontaminated using ultraviolet (UV) radiation in biosafety cabinets (BSCs), a common element of many academic, public health, and hospital laboratories. According to the literature, effective decontamination of N95 respirator masks or surgical masks requires UV-C doses of greater than 1 Jcm-2, which was achieved after 4.3 hours per side when placing the N95 at the bottom of the BSCs tested in this study. We then demonstrated complete inactivation of the human coronavirus NL63 on N95 mask material after 15 minutes of UV-C exposure at 61 cm (232 μWcm-2). Our results provide support to healthcare organizations looking for methods to extend their reserves of PPE.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top