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  1. AU="Erbes, Thalia"
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  1. Book ; Thesis: Lebensqualitätserfassung bei Mammakarzinompatientinnen in Abhängigkeit vom Operationsverfahren, Alter und adjuvanter Chemotherapie

    Erbes, Thalia

    2006  

    Author's details vorgelegt von Thalia Erbes, geb. Marinopoulos
    Language German
    Size 74 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 2006
    HBZ-ID HT014966774
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; Thesis: <dc:title>Biomarker potential of extracellular microRNA expression signatures in breast cancer under HER2-targeted therapy</dc:title>

    Sieger, Raika [Verfasser] / Erbes, Thalia [Akademischer Betreuer] / Erbes, Thalia [Sonstige] / Aumann, Konrad [Sonstige]

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Book ; Online ; Thesis: <dc:title>Quantitative serum proteomics to monitor therapy response of neoadjuvant chemotherapy in breast cancer</dc:title>

    Steenbuck, Ines D. [Verfasser] / Schilling, Oliver [Akademischer Betreuer] / Schilling, Oliver / Erbes, Thalia

    2024  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Article ; Online: Prognostic value and management of regional lymph nodes in locoregional breast cancer recurrence: a systematic review of the literature.

    Ge, Isabell / Erbes, Thalia / Juhasz-Böss, Ingolf

    Archives of gynecology and obstetrics

    2022  Volume 306, Issue 4, Page(s) 943–957

    Abstract: Purpose: Management of regional lymph nodes in breast cancer recurrence has been heterogeneous. To facilitate clinical practice, this review aims to give an overview on the prognosis, staging and operative management of (inapparent) regional lymph nodes. ...

    Abstract Purpose: Management of regional lymph nodes in breast cancer recurrence has been heterogeneous. To facilitate clinical practice, this review aims to give an overview on the prognosis, staging and operative management of (inapparent) regional lymph nodes.
    Methods: Current national and international guidelines are reviewed and a structured search of the literature between Jan 1, 1999 and Feb 1, 2021 on the repeat sentinel node biopsy (re-SNB) procedure was performed.
    Results: Positive regional lymph nodes in recurrent breast cancer indicate a poorer outcome with axillary recurrences being the most favorable tumor site among all nodal regions. Most preferred staging method is ultrasound ± guided biopsy. PET-CT, scintimammography, SPECT-CT may improve visualization of affected lymph nodes outside the axilla. Concerning operative management 30 articles on re-SNB were identified with a mean harvesting rate of 66.4%, aberrant drainage and aberrant metastasis in 1/3 of the cases. Total rate of metastasis is 17.9%. After previous axillary dissection (ALND) the re-SNB has a significantly lower harvesting rate and higher aberrant drainage and aberrant metastasis rate. The prognostic outcome after re-SNB has been favorable.
    Conclusion: Nodal status in recurrent disease has prognostic value. The choice of operative management of clinically inapparent regional lymph nodes during local recurrence should be based on the previous nodal staging method. Patients with previous ALND should be spared a second systematic ALND. Re-SNB or no axillary surgery at all are possible alternatives. Lymphoscintigraphy may be performed to identify extraaxillary drainage. However, for definite recommendations randomized controlled studies are heavily needed.
    MeSH term(s) Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Lymph Nodes/surgery ; Neoplasm Recurrence, Local/pathology ; Positron Emission Tomography Computed Tomography ; Prognosis ; Sentinel Lymph Node Biopsy/methods
    Language English
    Publishing date 2022-02-04
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-021-06352-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Real-World Data Analysis of CDK4/6 Inhibitor Therapy-A Patient-Centric Single Center Study.

    Ge, Isabell / Berner, Kai / Mathis, Marlene / Hensgen, Catherine / Mayer, Sebastian / Erbes, Thalia / Juhasz-Böss, Ingolf / Asberger, Jasmin

    Cancers

    2024  Volume 16, Issue 9

    Abstract: Background: The quest to comprehend the real-world efficacy of CDK4/6 inhibitors (CDKis) in breast cancer continues, as patient responses vary significantly.: Methods: This single-center retrospective study evaluated CDKi use outside the trial ... ...

    Abstract Background: The quest to comprehend the real-world efficacy of CDK4/6 inhibitors (CDKis) in breast cancer continues, as patient responses vary significantly.
    Methods: This single-center retrospective study evaluated CDKi use outside the trial condition from November 2016 to May 2020. Progression-free survival (PFS), time-to-treatment failure (TTF), short-term and prolonged treatment benefit (≥4 and ≥10 months), as well as prognostic and predictive markers were assessed with Kaplan-Meier and multivariate regression analyses.
    Results: Out of 86 identified patients, 58 (67.4%) had treatment failure of which 40 (46.5%) were due to progression. Median PFS and TTF were 12 and 8.5 months, respectively. A total of 57 (66.3%) and 42 (48.8%) patients experienced short-term and prolonged treatment benefit. Independent, significant predictors for PFS were progesterone receptor expression (HR: 0.88), multiple metastatic sites (HR: 2.56), and hepatic metastasis (HR: 2.01). Significant predictors for TTF were PR expression (HR: 0.86), multiple sites (HR: 3.29), adverse events (HR: 2.35), and diabetes (HR: 2.88). Aside from tumor biology and adverse events, treatment modifications like pausing and switching of CDKi were predictive for short-term (OR: 6.73) and prolonged (OR: 14.27) therapeutic benefit, respectively.
    Conclusions: These findings emphasize the importance of tailored treatment strategies, highlighting the role of PR expression, metastatic burden, and therapeutic adjustments in optimizing patient outcomes in real-world breast cancer management.
    Language English
    Publishing date 2024-05-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16091760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; Thesis: <dc:title>Untersuchungen zur Aktivierung olfaktorischer Rezeptoren in Brustkrebszellen als potentiellen Therapieansatz</dc:title>

    Klauser, Anna-Lena [Verfasser] / Erbes, Thalia [Akademischer Betreuer] / Erbes, Thalia [Sonstige] / Wölfle, Ute [Sonstige]

    2022  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Book ; Online ; Thesis: <dc:title>Endosomal Entrapment und Enhanced Endosomal Escape von Pseudomonas Exotoxin A basierten Immuntoxinen als neue Strategie bei der Behandlung des fortgeschrittenen Prostatakarzinoms</dc:title>

    Huber, Nathalie [Verfasser] / Wolf, Philipp [Akademischer Betreuer] / Wolf, Philipp / Erbes, Thalia

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Online ; Thesis: <dc:title>Photoimmuntherapie des Prostatakarzinoms</dc:title>

    Graf, Nele [Verfasser] / Wolf, Philipp [Akademischer Betreuer] / Wolf, Philipp / Erbes, Thalia

    2022  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Book ; Online ; Thesis: <dc:title>Der Einfluss der Epithelial-Mesenchymalen-Transition auf den olfaktorischen Signalweg in Mammakarzinom-Zelllinien</dc:title>

    Denzinger, Jonas [Verfasser] / Weiss, Daniela [Akademischer Betreuer] / Erbes, Thalia [Sonstige] / Wölfle, Ute [Sonstige]

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Book ; Online ; Thesis: <dc:title>Untersuchungen zu der antiproliferativen Wirkung von Vetiveracetat auf den Zellstoffwechsel von Brustkrebs in vitro</dc:title>

    Schorling, Helena [Verfasser] / Weiss, Daniela [Akademischer Betreuer] / Jäger, Markus [Akademischer Betreuer] / Erbes, Thalia [Sonstige] / Wölfle, Ute [Sonstige]

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    More links

    Kategorien

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