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  1. Book ; Online ; E-Book: Gesundheitswandern

    Eichmann, Björn / Erhardt, Tobias

    Auswirkungen auf das physische und psychische Wohlbefinden

    2020  

    Author's details Björn Eichmann, Tobias Erhardt (Hrsg.)
    Keywords Electronic books ; Wandern ; Gesundheitsförderung ; Psychische Gesundheit
    Subject Seelische Gesundheit ; Geistige Gesundheit ; Mental Health ; Mentalhealth ; Health Promotion ; Fernwandern ; Wanderung
    Language German
    Size 1 Online-Ressource (XV, 77 Seiten), Illustrationen, Diagramme
    Publisher Tectum Verlag
    Publishing place Baden-Baden
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020520001
    ISBN 978-3-8288-7471-8 ; 9783828844520 ; 3-8288-7471-1 ; 3828844529
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Garbage In and Garbage Out? On Waste Havens in Switzerland

    Erhardt, Tobias

    Environmental and resource economics. 2019 May, v. 73, no. 1

    2019  

    Abstract: This study investigates whether the introduction of a unit-based garbage fee induces waste dumping in nearby communities which do not implement such a policy. To identify the existence of a “waste haven effect”, I hypothesize that the likelihood of “ ... ...

    Abstract This study investigates whether the introduction of a unit-based garbage fee induces waste dumping in nearby communities which do not implement such a policy. To identify the existence of a “waste haven effect”, I hypothesize that the likelihood of “importing” or “exporting” waste depends on the distance to municipalities which have chosen the alternative policy option. Distances between municipalities are captured by routing data. I find some evidence for waste havens in a cross-section of Swiss municipalities. Exploiting variation in waste policy over time in a panel dataset for the canton of Ticino, I find that a decrease in distance is associated with an increase in the amount of waste collected by non-unit-pricing municipalities. The effect size is relatively small: An increase by one standard deviation in the impact factor applied to identify the waste haven effect increases the amount of collected waste per capita in non-unit-pricing municipalities by less than 3%.
    Keywords data collection ; issues and policy ; municipal solid waste ; standard deviation ; Switzerland
    Language English
    Dates of publication 2019-05
    Size p. 251-282.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 1479788-4
    ISSN 1573-1502 ; 0924-6460
    ISSN (online) 1573-1502
    ISSN 0924-6460
    DOI 10.1007/s10640-018-0260-x
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Bewegungsverhalten geriatrischer Patienten während eines stationären Klinikaufenthalts

    Erhardt, Tobias / Eichmann, Björn

    neuroreha

    2021  Volume 13, Issue 02, Page(s) 67–72

    Abstract: Geriatrische Patienten sind häufig von Multimorbidität betroffen und in ihrer Mobilität und Selbstständigkeit beeinträchtigt. Neben der medizinischen Versorgung ist die physiotherapeutische Betreuung ein wesentlicher Bestandteil, um die Lebensqualität ... ...

    Abstract Geriatrische Patienten sind häufig von Multimorbidität betroffen und in ihrer Mobilität und Selbstständigkeit beeinträchtigt. Neben der medizinischen Versorgung ist die physiotherapeutische Betreuung ein wesentlicher Bestandteil, um die Lebensqualität bestmöglich zu erhalten. Regelmäßige aktive Bewegung kann dabei zur Verbesserung der Mobilität und der Lebensqualität beitragen. In einer von unserer Arbeitsgruppe durchgeführten Pilotstudie (n = 9), die zum Mobilisationsmanagement geriatrischer Patienten während eines Klinikaufenthalts durchgeführt wurde (MgP-Studie), möchten wir verdeutlichen, wie sich die Problematik in der Praxis abbildet.
    Language German
    Publishing date 2021-06-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2492087-3
    ISSN 1611-7654 ; 1611-6496
    ISSN (online) 1611-7654
    ISSN 1611-6496
    DOI 10.1055/a-1472-9733
    Database Thieme publisher's database

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  4. Article: Interview mit Mike Steverding – „Als Sportphysio darfst du kein Weichei sein“

    Erhardt, Tobias

    physiopraxis

    2015  Volume 13, Issue 01, Page(s) 51–53

    Abstract: Mike Steverding betreut zahlreiche Bundesliga- und Nationalmannschaften. Beim Semestergespräch der SRH-Hochschule Karlsruhe berichtet er von seinen Erfahrungen im Spitzensport und erzählt, welche Eigenschaften ein angehender Sportphysiotherapeut ... ...

    Abstract Mike Steverding betreut zahlreiche Bundesliga- und Nationalmannschaften. Beim Semestergespräch der SRH-Hochschule Karlsruhe berichtet er von seinen Erfahrungen im Spitzensport und erzählt, welche Eigenschaften ein angehender Sportphysiotherapeut mitbringen sollte.
    Language German
    Publishing date 2015-01-01
    Publisher © Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2272772-3
    ISSN 1869-5515 ; 1439-023X
    ISSN (online) 1869-5515
    ISSN 1439-023X
    DOI 10.1055/s-0034-1544020
    Database Thieme publisher's database

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  5. Article ; Online: Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells.

    Bachmann, Cornel Manuel / Janitschke, Daniel / Lauer, Anna Andrea / Erhardt, Tobias / Hartmann, Tobias / Grimm, Marcus Otto Walter / Grimm, Heike Sabine

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood. As a ligand for peroxisome proliferative-activated receptor-alpha (PPARα), which is expressed in many tissues, it induces the transcription of numerous genes for ... ...

    Abstract Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood. As a ligand for peroxisome proliferative-activated receptor-alpha (PPARα), which is expressed in many tissues, it induces the transcription of numerous genes for carbohydrate and lipid-metabolism. However, nothing is known about how intracellular lipid-homeostasis and, in particular, triglycerides are affected. As triglycerides are stored in lipid-droplets, which are known to be associated with many diseases, such as Alzheimer's disease, cancer, fatty liver disease and type-2 diabetes, treatment with gemfibrozil could adversely affect these diseases. To address the question whether gemfibrozil also affects intracellular lipid-levels, SH-SY5Y, HEK and Calu-3 cells, representing three different metabolically active organs (brain, lung and kidney), were incubated with gemfibrozil and subsequently analyzed semi-quantitatively by mass-spectrometry. Importantly, all cells showed a strong increase in intracellular triglycerides (SH-SY5Y: 170.3%; HEK: 272.1%; Calu-3: 448.1%), suggesting that the decreased triglyceride-levels might be due to an enhanced cellular uptake. Besides the common intracellular triglyceride increase, a cell-line specific alteration in acylcarnitines are found, suggesting that especially in neuronal cell lines gemfibrozil increases the transport of fatty acids to mitochondria and therefore increases the turnover of fatty acids for the benefit of additional energy supply, which could be important in diseases, such as Alzheimer's disease.
    MeSH term(s) Humans ; Gemfibrozil/pharmacology ; Alzheimer Disease/drug therapy ; Neuroblastoma/drug therapy ; Triglycerides/metabolism ; Fatty Acids ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use
    Chemical Substances Gemfibrozil (Q8X02027X3) ; Triglycerides ; Fatty Acids ; Hypolipidemic Agents
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032972
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vitamin D and Its Analogues: From Differences in Molecular Mechanisms to Potential Benefits of Adapted Use in the Treatment of Alzheimer's Disease.

    Thiel, Andrea / Hermanns, Carina / Lauer, Anna Andrea / Reichrath, Jörg / Erhardt, Tobias / Hartmann, Tobias / Grimm, Marcus Otto Walter / Grimm, Heike Sabine

    Nutrients

    2023  Volume 15, Issue 7

    Abstract: Lifestyle habits and insufficient sunlight exposure lead to a high prevalence of vitamin D hypovitaminosis, especially in the elderly. Recent studies suggest that in central Europe more than 50% of people over 60 years are not sufficiently supplied with ... ...

    Abstract Lifestyle habits and insufficient sunlight exposure lead to a high prevalence of vitamin D hypovitaminosis, especially in the elderly. Recent studies suggest that in central Europe more than 50% of people over 60 years are not sufficiently supplied with vitamin D. Since vitamin D hypovitaminosis is associated with many diseases, such as Alzheimer's disease (AD), vitamin D supplementation seems to be particularly useful for this vulnerable age population. Importantly, in addition to vitamin D, several analogues are known and used for different medical purposes. These vitamin D analogues differ not only in their pharmacokinetics and binding affinity to the vitamin D receptor, but also in their potential side effects. Here, we discuss these aspects, especially those of the commonly used vitamin D analogues alfacalcidol, paricalcitol, doxercalciferol, tacalcitol, calcipotriol, and eldecalcitol. In addition to their pleiotropic effects on mechanisms relevant to AD, potential effects of vitamin D analogues on comorbidities common in the context of geriatric diseases are summarized. AD is defined as a complex neurodegenerative disease of the central nervous system and is commonly represented in the elderly population. It is usually caused by extracellular accumulation of amyloidogenic plaques, consisting of amyloid (Aβ) peptides. Furthermore, the formation of intracellular neurofibrillary tangles involving hyperphosphorylated tau proteins contributes to the pathology of AD. In conclusion, this review emphasizes the importance of an adequate vitamin D supply and discusses the specifics of administering various vitamin D analogues compared with vitamin D in geriatric patients, especially those suffering from AD.
    MeSH term(s) Humans ; Aged ; Alzheimer Disease/metabolism ; Neurodegenerative Diseases/drug therapy ; Vitamin D ; Vitamins ; tau Proteins ; Amyloid beta-Peptides/metabolism
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins ; tau Proteins ; Amyloid beta-Peptides
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15071684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Netzwerk. Pädagogische Akzentuierung entwickeln. Im wissenschaftlichen Beirat: Tobias Erhardt

    Erhardt, Tobias

    Zeitschrift für Physiotherapeuten

    2012  Volume 64, Issue 9, Page(s) 20

    Language German
    Document type Article
    ZDB-ID 2274399-6
    ISSN 1614-0397
    Database Current Contents Medicine

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  8. Article: Heterogenität im Unterricht – Vielfalt bereichert

    Erhardt, Tobias

    physiopraxis

    2011  Volume 9, Issue 04, Page(s) 38–40

    Language German
    Publishing date 2011-04-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2272772-3
    ISSN 1869-5515 ; 1439-023X
    ISSN (online) 1869-5515
    ISSN 1439-023X
    DOI 10.1055/s-0031-1277698
    Database Thieme publisher's database

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  9. Article: Den Belastungen des Schulranzens mit gezielter Anspannung entgegenwirken

    Kirchberger, Joris / Eichmann, Björn / Erhardt, Tobias

    manuelletherapie

    2020  Volume 24, Issue 02, Page(s) 87–95

    Abstract: Immer mehr Kinder leiden an Rückenschmerzen, in der Altersklasse von 11–17 Jahren sogar mehr als jedes 4. Kind. Als Ursache wird unter anderem der Schulranzen angenommen. Diese randomisierte, kontrollierte Studie mit 59 Kindern ... ...

    Abstract Immer mehr Kinder leiden an Rückenschmerzen, in der Altersklasse von 11–17 Jahren sogar mehr als jedes 4. Kind. Als Ursache wird unter anderem der Schulranzen angenommen. Diese randomisierte, kontrollierte Studie mit 59 Kindern untersuchte, ob sich die Schmerzen durch ein Rückentraining reduzieren lassen. Die beiden Interventionsgruppen führten ein- bzw. zweimal pro Woche ein Rückentraining durch, die 3. Gruppe diente als Kontrollgruppe. Es zeigte sich kein signifikanter Zusammenhang zwischen dem Gewicht des Schulranzens und dem Auftreten von Rückenschmerzen. Die Interventionsgruppen verbesserten im Vergleich zur Kontrollgruppe jedoch signifikant ihre Koordination. Die Studienergebnisse liefern Denkanstöße für die Gesundheitspädagogik an Grundschulen.
    Keywords Schulranzen ; Rückenschmerzen ; Kinder ; Training ; schoolbag ; back pain ; children ; exercise
    Language German
    Publishing date 2020-05-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2138834-9
    ISSN 1439-2348 ; 1433-2671
    ISSN (online) 1439-2348
    ISSN 1433-2671
    DOI 10.1055/a-1120-3193
    Database Thieme publisher's database

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  10. Article: Heterogenität im Unterricht – Vielfalt bereichert

    Erhardt, Tobias

    ergopraxis

    2011  Volume 4, Issue 06, Page(s) 34–36

    Language German
    Publishing date 2011-06-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2423003-0
    ISSN 1869-5507 ; 1439-2283
    ISSN (online) 1869-5507
    ISSN 1439-2283
    DOI 10.1055/s-0031-1280910
    Database Thieme publisher's database

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