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  1. Article: The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness.

    Mendelson, Asher A / Erickson, Dustin / Villar, Rodrigo

    Frontiers in physiology

    2023  Volume 14, Page(s) 1170429

    Abstract: Skeletal muscle dysfunction after critical illness, defined as ICU-acquired weakness (ICU-AW), is a complex and multifactorial syndrome that contributes significantly to long-term morbidity and reduced quality of life for ICU survivors and caregivers. ... ...

    Abstract Skeletal muscle dysfunction after critical illness, defined as ICU-acquired weakness (ICU-AW), is a complex and multifactorial syndrome that contributes significantly to long-term morbidity and reduced quality of life for ICU survivors and caregivers. Historically, research in this field has focused on pathological changes within the muscle itself, without much consideration for their
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1170429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice.

    Ahmadpour, Noushin / Kantroo, Meher / Stobart, Michael J / Meza-Resillas, Jessica / Shabanipour, Shahin / Parra-Nuñez, Jesus / Salamovska, Tetiana / Muzaleva, Anna / O'Hara, Finnegan / Erickson, Dustin / Di Gaetano, Bruno / Carrion-Falgarona, Sofia / Weber, Bruno / Lamont, Alana / Lavine, Natalie E / Kauppinen, Tiina M / Jackson, Michael F / Stobart, Jillian L

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1571

    Abstract: Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown approach to ... ...

    Abstract Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown approach to selectively reduce NMDARs in mouse cortical astrocytes decreases astrocyte Ca
    MeSH term(s) Mice ; Animals ; Astrocytes/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Vibrissae/metabolism ; Neurons/metabolism ; Signal Transduction
    Chemical Substances Receptors, N-Methyl-D-Aspartate
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45989-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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