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  1. Article: Betreuung von Sportlern unter Hitzebedingungen

    Erz, Gunnar / Nieß, Andreas M.

    Sportphysio

    2021  Volume 09, Issue 03, Page(s) 129–138

    Abstract: Klimatische Extreme wie Hitze können zu einem leistungslimitierenden Faktor werden. Daneben drohen zahlreiche gesundheitliche Probleme. Die richtige Beratung und entsprechende Maßnahmen in der Betreuung von Sportlern können unter Hitzebedingungen nicht ... ...

    Abstract Klimatische Extreme wie Hitze können zu einem leistungslimitierenden Faktor werden. Daneben drohen zahlreiche gesundheitliche Probleme. Die richtige Beratung und entsprechende Maßnahmen in der Betreuung von Sportlern können unter Hitzebedingungen nicht nur die Leistung ausschlaggebend beeinflussen.
    Language German
    Publishing date 2021-06-25
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2196-596X ; 2196-5951
    ISSN (online) 2196-596X
    ISSN 2196-5951
    DOI 10.1055/a-1463-7552
    Database Thieme publisher's database

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  2. Article ; Online: miRNAs as markers for the development of individualized training regimens: A pilot study.

    Widmann, Manuel / Mattioni Maturana, Felipe / Burgstahler, Christof / Erz, Gunnar / Schellhorn, Philipp / Fragasso, Annunziata / Schmitt, Angelika / Nieß, Andreas M / Munz, Barbara

    Physiological reports

    2022  Volume 10, Issue 5, Page(s) e15217

    Abstract: Small, non-coding RNAs (microRNAs) have been shown to regulate gene expression in response to exercise in various tissues and organs, thus possibly coordinating their adaptive response. Thus, it is likely that differential microRNA expression might be ... ...

    Abstract Small, non-coding RNAs (microRNAs) have been shown to regulate gene expression in response to exercise in various tissues and organs, thus possibly coordinating their adaptive response. Thus, it is likely that differential microRNA expression might be one of the factors that are responsible for different training responses of different individuals. Consequently, determining microRNA patterns might be a promising approach toward the development of individualized training strategies. However, little is known on (1) microRNA patterns and their regulation by different exercise regimens and (2) possible correlations between these patterns and individual training adaptation. Here, we present microarray data on skeletal muscle microRNA patterns in six young, female subjects before and after six weeks of either moderate-intensity continuous or high-intensity interval training on a bicycle ergometer. Our data show that n = 36 different microRNA species were regulated more than twofold in this cohort (n = 28 upregulated and n = 8 downregulated). In addition, we correlated baseline microRNA patterns with individual changes in VO
    MeSH term(s) Adaptation, Physiological ; Biomarkers/metabolism ; Exercise/physiology ; Female ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Muscle, Skeletal/metabolism ; Pilot Projects
    Chemical Substances Biomarkers ; MicroRNAs
    Language English
    Publishing date 2022-03-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.15217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Skeletal Muscle MicroRNA Patterns in Response to a Single Bout of Exercise in Females: Biomarkers for Subsequent Training Adaptation?

    Grieb, Alexandra / Schmitt, Angelika / Fragasso, Annunziata / Widmann, Manuel / Mattioni Maturana, Felipe / Burgstahler, Christof / Erz, Gunnar / Schellhorn, Philipp / Nieß, Andreas M / Munz, Barbara

    Biomolecules

    2023  Volume 13, Issue 6

    Abstract: microRNAs (miRs) have been proposed as a promising new class of biomarkers in the context of training adaptation. Using microarray analysis, we studied skeletal muscle miR patterns in sedentary young healthy females ( ...

    Abstract microRNAs (miRs) have been proposed as a promising new class of biomarkers in the context of training adaptation. Using microarray analysis, we studied skeletal muscle miR patterns in sedentary young healthy females (
    MeSH term(s) Humans ; Female ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Oxygen Consumption ; Oxygen/metabolism ; Exercise/physiology ; Muscle, Skeletal/metabolism ; Biomarkers/metabolism
    Chemical Substances MicroRNAs ; Oxygen (S88TT14065) ; Biomarkers
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13060884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Responders and non-responders to aerobic exercise training: beyond the evaluation of

    Mattioni Maturana, Felipe / Soares, Rogerio N / Murias, Juan M / Schellhorn, Philipp / Erz, Gunnar / Burgstahler, Christof / Widmann, Manuel / Munz, Barbara / Thiel, Ansgar / Nieß, Andreas M

    Physiological reports

    2021  Volume 9, Issue 16, Page(s) e14951

    Abstract: The evaluation of the maximal oxygen uptake ( ...

    Abstract The evaluation of the maximal oxygen uptake (
    MeSH term(s) Adaptation, Physiological ; Adult ; Blood Glucose/metabolism ; Blood Pressure ; Body Composition ; Exercise ; Female ; Heart/physiology ; Heart Rate ; Humans ; Male ; Microvessels/physiology ; Oxygen Consumption
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2021-08-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.14951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Individual cardiovascular responsiveness to work-matched exercise within the moderate- and severe-intensity domains.

    Maturana, Felipe Mattioni / Schellhorn, Philipp / Erz, Gunnar / Burgstahler, Christof / Widmann, Manuel / Munz, Barbara / Soares, Rogerio N / Murias, Juan M / Thiel, Ansgar / Nieß, Andreas M

    European journal of applied physiology

    2021  Volume 121, Issue 7, Page(s) 2039–2059

    Abstract: Purpose: We investigated the cardiovascular individual response to 6 weeks (3×/week) of work-matched within the severe-intensity domain (high-intensity interval training, HIIT) or moderate-intensity domain (moderate-intensity continuous training, MICT). ...

    Abstract Purpose: We investigated the cardiovascular individual response to 6 weeks (3×/week) of work-matched within the severe-intensity domain (high-intensity interval training, HIIT) or moderate-intensity domain (moderate-intensity continuous training, MICT). In addition, we analyzed the cardiovascular factors at baseline underlying the response variability.
    Methods: 42 healthy sedentary participants were randomly assigned to HIIT or MICT. We applied the region of practical equivalence-method for identifying the levels of responders to the maximal oxygen uptake (V̇O
    Results: Despite that HIIT and MICT induced significant increases in V̇O
    Conclusion: Our findings highlight the critical influence of exercise-intensity domains and biological variability on the individual V̇O
    MeSH term(s) Adult ; Bayes Theorem ; Cardiorespiratory Fitness/physiology ; Female ; High-Intensity Interval Training/methods ; Humans ; Male ; Oxygen Consumption/physiology ; Sedentary Behavior
    Language English
    Publishing date 2021-04-03
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-021-04676-7
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.195: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Book ; Online ; Thesis: Korrelation zwischen EKG-Veränderungen und kardialen Parametern in hochtrainierten, asymptomatischen männlichen Ausdauerathleten – evaluiert mit der kardialen MRT

    Erz, Gunnar [Verfasser] / Burgstahler, Christof [Akademischer Betreuer]

    2015  

    Author's details Gunnar Erz ; Betreuer: Christof Burgstahler
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Tübingen
    Publishing place Tübingen
    Document type Book ; Online ; Thesis
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  7. Article ; Online: Correlation between ECG abnormalities and cardiac parameters in highly trained asymptomatic male endurance athletes: evaluation using cardiac magnetic resonance imaging.

    Erz, Gunnar / Mangold, Stefanie / Franzen, Erik / Claussen, Claus D / Niess, Andreas M / Burgstahler, Christof / Kramer, Ulrich

    The international journal of cardiovascular imaging

    2012  Volume 29, Issue 2, Page(s) 325–334

    Abstract: Intensive endurance training can induce abnormal ECG patterns at rest. These alterations are differentiated into minor, mildly or distinctly abnormal ECG patterns. Echocardiographic data imply a correlation between the extent of these alterations and ... ...

    Abstract Intensive endurance training can induce abnormal ECG patterns at rest. These alterations are differentiated into minor, mildly or distinctly abnormal ECG patterns. Echocardiographic data imply a correlation between the extent of these alterations and cardiac parameters like cardiac volume or wall thickness. In comparison to echocardiography, cardiac magnetic resonance imaging (MRI) is characterized by high reproducibility and accuracy. The aim of this study was to investigate the correlation between ECG alterations and cardiac parameters in highly trained asymptomatic male endurance athletes as assessed using cardiac MRI. Forty-five asymptomatic male endurance athletes (mean age 40 ± 8.9 years., range 19-59 years., 13 ± 5 h of training per week) underwent a cardiac MRI examination in addition to a resting ECG. Based on the ECG patterns at rest, the athletes were divided into groups with normal or minor (group 1) and mild or distinct (group 2) alterations. Steady-state free-precession cine MRI was used to calculate left and right ventricular end-diastolic volume, end-systolic volume, stroke volume, ejection fraction, and myocardial mass (MM). Late enhancement imaging was used to exclude structural alterations or myocardial scarring. Athletes in group 1 and 2 did not differ significantly in terms of age, height, body weight, body mass index or hours of training per week. Athletes with mildly or distinctly abnormal ECG patterns showed a significantly higher MM than athletes with minor ECG alterations at rest or normal resting ECG values (156.4 ± 18.4 g vs. 140.5 ± 20.0 g; p = 0.0103). The differences persisted when the values were corrected for body surface area (80.0 ± 7.4 g/m² vs. 73.4 ± 8.3 g; p = 0.0093). All other assessed cardiac parameters did not differ between the two groups. Pathological myocardial enhancement was detected only in one patient with a minor abnormal ECG. Male asymptomatic endurance athletes with mildly or distinctly abnormal ECG patterns at rest are characterized by a higher myocardial mass than comparable athletes with minor alterations or normal ECG at rest. Thus, the extent of ECG-abnormalities seems to be mainly the result of an increase in myocardial mass. Additionally, the absence of mild or distinct ECG alterations does not exclude the presence of pathological late gadolinium enhancement.
    MeSH term(s) Adult ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/pathology ; Arrhythmias, Cardiac/physiopathology ; Asymptomatic Diseases ; Cardiomegaly, Exercise-Induced ; Contrast Media ; Electrocardiography ; Heart Rate ; Humans ; Linear Models ; Magnetic Resonance Imaging, Cine ; Male ; Middle Aged ; Myocardium/pathology ; Organometallic Compounds ; Physical Endurance ; Predictive Value of Tests ; Stroke Volume ; Ventricular Function, Left ; Young Adult
    Chemical Substances Contrast Media ; Organometallic Compounds ; gadobutrol (1BJ477IO2L)
    Language English
    Publishing date 2012-06-22
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-012-0082-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2104: Show issues Location:
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  8. Article ; Online: Comparison of morphological and functional adaptations of the heart in highly trained triathletes and long-distance runners using cardiac magnetic resonance imaging.

    Franzen, Erik / Mangold, Stefanie / Erz, Gunnar / Claussen, Claus D / Niess, Andreas M / Kramer, Ulrich / Burgstahler, Christof

    Heart and vessels

    2012  Volume 28, Issue 5, Page(s) 626–631

    Abstract: Athlete's heart" is characterized by an increase in ventricular chamber sizes and myocardial mass (MM), and is mainly observed in endurance athletes. At present, it remains unclear whether cardiac adaptations in long-distance runners differ from those ... ...

    Abstract "Athlete's heart" is characterized by an increase in ventricular chamber sizes and myocardial mass (MM), and is mainly observed in endurance athletes. At present, it remains unclear whether cardiac adaptations in long-distance runners differ from those in triathletes. Twenty male triathletes (mean age 38.7 ± 6.2 years) and 20 male marathon runners (mean age 44.1 ± 7.9) underwent cardiac magnetic resonance imaging to calculate left and right ventricular end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), and MM. Late-enhancement (LE) imaging was used to exclude structural alterations or myocardial scarring. EDV, ESV, SV, and EF for the left and right ventricles, as well as MM, did not differ between long-distance runners and triathletes, although the weekly training volume was significantly higher in triathletes (17.05 vs 9.95 h/week, P < 0.0001). There was a significant correlation between weekly training volume and right and left EDV, right and left ESV as well as MM within the study group. Myocardial LE was absent in all athletes. Highly trained male long-distance runners and triathletes have comparable cardiac parameters. However, the extent of physical training seems to be associated with the degree of cardiac adaptation in endurance athletes. The absence of LE supports the idea that athlete's heart is a nonpathological adaptation of the cardiovascular system.
    MeSH term(s) Adaptation, Physiological ; Adult ; Bicycling ; Cardiomegaly, Exercise-Induced ; Contrast Media ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Organometallic Compounds ; Physical Conditioning, Human ; Physical Endurance ; Predictive Value of Tests ; Running ; Stroke Volume ; Swimming ; Ventricular Function, Left ; Ventricular Function, Right
    Chemical Substances Contrast Media ; Organometallic Compounds ; gadobutrol (1BJ477IO2L)
    Language English
    Publishing date 2012-09-15
    Publishing country Japan
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-012-0289-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2049: Show issues Location:
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