LIVIVO - Search results -

Search results

Result 1 - 10 of total 11

Search options

Article ; Online: Surgical Explantation of a Dehiscent Cardioband.

Eschenbach, Lena Katharina / Prinzing, Anatol / Herold, Ulf / Erlebach, Magdalena / Bleiziffer, Sabine

2019 Volume 12, Issue 9, Page(s) e79–e80

MeSH term(s)	Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Device Removal ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/instrumentation ; Humans ; Male ; Middle Aged ; Mitral Valve/diagnostic imaging ; Mitral Valve/physiopathology ; Mitral Valve/surgery ; Mitral Valve Annuloplasty/adverse effects ; Mitral Valve Annuloplasty/instrumentation ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/physiopathology ; Mitral Valve Insufficiency/surgery ; Prosthesis Design ; Prosthesis Failure ; Recovery of Function ; Reoperation ; Treatment Outcome
Language	English
Publishing date	2019-02-27
Publishing country	United States
Document type	Case Reports ; Video-Audio Media
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2018.12.038
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6669: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online ; Thesis: Die Cone-Methode nach da Silva bei Ebstein-Anomalie

Eschenbach, Lena Katharina [Verfasser] / Sodian, Ralf [Akademischer Betreuer]

Auswirkungen auf die Klappenfunktion und den rechten Ventrikel

2018

Author's details	Lena Katharina Eschenbach ; Betreuer: Ralf Sodian
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	German
Publisher	Universitätsbibliothek der Ludwig-Maximilians-Universität
Publishing place	München
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Stroke after transcatheter aortic valve replacement: A severe complication with low predictability.

Eschenbach, Lena K / Erlebach, Magdalena / Deutsch, Marcus-André / Ruge, Hendrik / Bleiziffer, Sabine / Holzer, Lisa / Krane, Markus / Voss, Stephanie / Lange, Ruediger / Burri, Melchior

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2022 Volume 99, Issue 6, Page(s) 1897–1905

Abstract: Objectives: We aimed to describe stroke and transient ischemic attacks (TIAs) after transcatheter aortic valve replacement (TAVR) and to identify associated risk factors.: Background: Stroke/TIA after TAVR is a major complication.: Methods: A ... ...

Abstract	Objectives: We aimed to describe stroke and transient ischemic attacks (TIAs) after transcatheter aortic valve replacement (TAVR) and to identify associated risk factors. Background: Stroke/TIA after TAVR is a major complication. Methods: A total of 1919 concomitant patients underwent TAVR in a single center from 2007 to 2017. Pre-, intra-, and postprocedural data were collected prospectively in a database and analyzed retrospectively. Stroke and TIA were documented according to the Valve Academic Research Consortium-II criteria. Logistic regression was used to determine risk factors for stroke after TAVR. Results: Mean age was 79.5 ± 6.8 years, mean logistic EuroScore was 17.6% ± 12.8%, and 51.8% (n = 994) of the patients were female. Stroke/TIA occurred in 76 patients (3.9%), 1.9% were disabling, and 1.6% nondisabling. The predominant type of stroke were territorial ischemic lesions (82.4%), with primary bleeding in 4.4% and border zone infarctions in 4.4%. Left-sided lesions were more common (45.6% left sided vs. 25% right sided) and 13.2% of the lesions were bilateral (4.4% no finding and 11.8% missing data). In multivariate logistic regression, prior stroke (odds ratio [OR] = 1.83, p = 0.046) and initial experience (first 300 TAVR implanted at our center) were identified as independent risk factors for stroke/TIA during the first 30 days (OR = 1.95, p = 0.045). Overall, the occurrence of stroke had a highly significant impact on a 30-day mortality (13.2% vs. 4.9% in patients without stroke (p = 0.005). Conclusion: Stroke within the first 30 days after TAVR severely impairs 30-day survival. We identified prior stroke and initial experience as significant independent risk factors for the occurrence of stroke after TAVR.
MeSH term(s)	Aged ; Aged, 80 and over ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/complications ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Female ; Humans ; Ischemic Attack, Transient/epidemiology ; Ischemic Attack, Transient/etiology ; Male ; Retrospective Studies ; Risk Factors ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/etiology ; Time Factors ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
Language	English
Publishing date	2022-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.30143
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1226: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Preoperative Venovenous ECMO in an Infant With Late Diagnosis of Hypoplastic Left Heart Syndrome.

Eschenbach, Lena K / Kasnar-Samprec, Jelena / Ackermann, Kilian / Schreiber, Christian / Lange, Rudiger / Cleuziou, Julie

World journal for pediatric & congenital heart surgery

2017 Volume 11, Issue 4, Page(s) NP41–NP43

Abstract: Late diagnosis and late referral for the Norwood stage 1 procedure in patients with hypoplastic left heart syndrome is rare and associated with a higher mortality. We present a case of a cyanotic almost five-week-old infant with hypoplastic left heart ... ...

Abstract	Late diagnosis and late referral for the Norwood stage 1 procedure in patients with hypoplastic left heart syndrome is rare and associated with a higher mortality. We present a case of a cyanotic almost five-week-old infant with hypoplastic left heart syndrome, highly restrictive foramen ovale, and patent ductus arteriosus, who was bridged with venovenous extracorporeal membrane oxygenation to the Norwood stage 1 procedure.
MeSH term(s)	Delayed Diagnosis ; Echocardiography ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Hypoplastic Left Heart Syndrome/diagnosis ; Hypoplastic Left Heart Syndrome/therapy ; Infant ; Male ; Norwood Procedures/methods ; Preoperative Care/methods
Language	English
Publishing date	2017-07-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2550261-X
ISSN	2150-136X ; 2150-1351
ISSN (online)	2150-136X
ISSN	2150-1351
DOI	10.1177/2150135117697228
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Impact of transcatheter aortic valve implantation on surgical aortic valve.

Vaquerizo, Beatriz / Bleiziffer, Sabine / Wottke, Michael / Spaziano, Marco / Eschenbach, Lena / Lange, Rüdiger / Piazza, Nicolo

International journal of cardiology

2017 Volume 243, Page(s) 145–149

Abstract: Introduction and objectives: TAVR is thought to change the volumes, characteristics, and outcomes of patients with aortic stenosis undergoing SAVR. We sought to investigate the impact of increasing transcatheter aortic valve replacement (TAVR) volumes ... ...

Abstract	Introduction and objectives: TAVR is thought to change the volumes, characteristics, and outcomes of patients with aortic stenosis undergoing SAVR. We sought to investigate the impact of increasing transcatheter aortic valve replacement (TAVR) volumes on surgical aortic valve replacement (SAVR) volumes and to assess the evolution in baseline demographics and its impact on 30-day clinical outcomes across TAVR and SAVR patients. Methods: From June 2007 through September 2015, 3543 consecutive patients with severe aortic stenosis who underwent TAVR (n=1407) or SAVR (n=2136) in a single center were subcategorized into nine cohorts defined by procedure year. These cohorts were examined for differences in volumes, baseline demographics, and 30-day mortality. Results: We observed a reduction in SAVR compared to TAVR volumes over time: from 79% in 2007 to 48% in 2015 (P<0.001). The mean STS score of the TAVR patients decreased significantly from 6.8 in 2007 to 4.3 in 2015 (P<0.001). Concurrently, the crude 30-day mortality for TAVR improved from 11% in 2007 to 3% in 2015 (P<0.001). The overall 30-day mortality was similar between TAVR and SAVR after adjusting for the independent predictors of mortality (adjusted odds ratio (OR)=0.758; P=0.2). Conclusions: In a high-volume surgical center, we observed a significant decrease in patients undergoing SAVR compared to TAVR. We show an important shift toward the selection of lower surgical risk patients for TAVR. Overall 30-day mortality was similar between TAVR and SAVR after adjusting for baseline characteristics.
Language	English
Publishing date	2017-09-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2017.05.074
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1673: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage.

Lahm, Harald / Dreßen, Martina / Beck, Nicole / Doppler, Stefanie / Deutsch, Marcus-André / Matsushima, Shunsuke / Neb, Irina / König, Karl Christian / Sideris, Konstantinos / Voss, Stefanie / Eschenbach, Lena / Puluca, Nazan / Deisenhofer, Isabel / Doll, Sophia / Holdenrieder, Stefan / Mann, Matthias / Lange, Rüdiger / Krane, Markus

Scientific reports

2019 Volume 9, Issue 1, Page(s) 9986

Abstract: Myosin binding protein H-like (MYBPHL) is a protein associated with myofilament structures in atrial tissue. The protein exists in two isoforms that share an identical amino acid sequence except for a deletion of 23 amino acids in isoform 2. In this ... ...

Abstract	Myosin binding protein H-like (MYBPHL) is a protein associated with myofilament structures in atrial tissue. The protein exists in two isoforms that share an identical amino acid sequence except for a deletion of 23 amino acids in isoform 2. In this study, MYBPHL was found to be expressed preferentially in atrial tissue. The expression of isoform 2 was almost exclusively restricted to the atria and barely detectable in the ventricle, arteria mammaria interna, and skeletal muscle. After atrial damage induced by cryo- or radiofrequency ablation, MYBPHL was rapidly and specifically released into the peripheral circulation in a time-dependent manner. The plasma MYBPHL concentration remained substantially elevated up to 24 hours after the arrival of patients at the intensive care unit. In addition, the recorded MYBPHL values were strongly correlated with those of the established biomarker CK-MB. In contrast, an increase in MYBPHL levels was not evident in patients undergoing aortic valve replacement or transcatheter aortic valve implantation. In these patients, the values remained virtually constant and never exceeded the concentration in the plasma of healthy controls. Our findings suggest that MYBPHL can be used as a precise and reliable biomarker to specifically predict atrial myocardial damage.
MeSH term(s)	Alternative Splicing ; Atrial Fibrillation/blood ; Atrial Fibrillation/therapy ; Biomarkers/blood ; Biomarkers/metabolism ; Cryosurgery/adverse effects ; Cytoskeletal Proteins/blood ; Cytoskeletal Proteins/metabolism ; Heart Atria/injuries ; Heart Atria/metabolism ; Heart Ventricles/metabolism ; Humans ; Intensive Care Units ; Muscle, Skeletal/metabolism ; Organ Specificity ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Radiofrequency Ablation/adverse effects ; Up-Regulation
Chemical Substances	Biomarkers ; Cytoskeletal Proteins ; MYBPHL protein, human ; Protein Isoforms
Language	English
Publishing date	2019-07-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-46123-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Da Silva's cone repair for Ebstein's anomaly: effect on right ventricular size and function.

Lange, Rüdiger / Burri, Melchior / Eschenbach, Lena Katharina / Badiu, Catalin Constantin / da Silva, José Pedro / Nagdyman, Nicole / Fratz, Sohrab / Hörer, Jürgen / Kühn, Andreas / Schreiber, Christian / Vogt, Manfred Otto

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2015 Volume 48, Issue 2, Page(s) 316–20; discussion 320–1

Abstract: Objectives: Da Silva's cone repair is a novel technique for surgical reconstruction of the tricuspid valve and the right ventricle (RV) in Ebstein's anomaly. The technique consists of extensive leaflet mobilization, longitudinal plication of the ... ...

Abstract	Objectives: Da Silva's cone repair is a novel technique for surgical reconstruction of the tricuspid valve and the right ventricle (RV) in Ebstein's anomaly. The technique consists of extensive leaflet mobilization, longitudinal plication of the atrialized ventricle and cone-shaped reconstruction of the tricuspid valve, allowing for leaflet-to-leaflet coaptation. We evaluated the influence of Da Silva's cone repair on tricuspid competency, right ventricular size and function. Methods: From February 2010 until July 2013, 20 patients (median age 30.0 years, range 6.6-68.3 years) underwent Da Silva's cone repair. A 4- to 6-mm interatrial communication was left in all patients. Echocardiographic studies and magnetic resonance imaging (MRI) before and after the repair were evaluated. Results: Median follow-up was 11 (0.5-36) months. There were 2 early deaths and no late death. Echocardiography at follow-up revealed mild or absent tricuspid regurgitation in 16 patients. Two patients showed moderate tricuspid insufficiency. MRI studies showed that the mean functional RV end-diastolic volume decreased after surgery (pre 334 [135-656] ml; post 175 [115-404] ml, P < 0.001). The mean RV ejection fraction decreased (pre 47 ± 10%; post 35 ± 13%, P = 0.001), and the mean antegrade net stroke volume of the RV increased (pre 65 ± 28 ml; post 75 ± 30 ml, P = 0.057). Conclusions: Da Silva's cone repair for Ebstein's anomaly creates excellent valve function in all patients. Consecutively, the size of the RV decreases and the antegrade net stroke volume increases 6 months after the operation.
MeSH term(s)	Adolescent ; Adult ; Aged ; Child ; Ebstein Anomaly/pathology ; Ebstein Anomaly/physiopathology ; Ebstein Anomaly/surgery ; Female ; Follow-Up Studies ; Heart Ventricles/pathology ; Heart Ventricles/surgery ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Reoperation ; Stroke Volume/physiology ; Survival Analysis ; Treatment Outcome ; Tricuspid Valve/physiopathology ; Tricuspid Valve/surgery ; Tricuspid Valve Insufficiency/diagnostic imaging ; Tricuspid Valve Insufficiency/surgery ; Ultrasonography ; Ventricular Function, Right/physiology ; Young Adult
Language	English
Publishing date	2015-08
Publishing country	Germany
Document type	Evaluation Studies ; Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezu472
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2303: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement.

Yoon, Sung-Han / Kim, Won-Keun / Dhoble, Abhijeet / Milhorini Pio, Stephan / Babaliaros, Vasilis / Jilaihawi, Hasan / Pilgrim, Thomas / De Backer, Ole / Bleiziffer, Sabine / Vincent, Flavien / Shmidt, Tobias / Butter, Christian / Kamioka, Norihiko / Eschenbach, Lena / Renker, Matthias / Asami, Masahiko / Lazkani, Mohamad / Fujita, Buntaro / Birs, Antoinette /

Barbanti, Marco / Pershad, Ashish / Landes, Uri / Oldemeyer, Brad / Kitamura, Mitusnobu / Oakley, Luke / Ochiai, Tomoki / Chakravarty, Tarun / Nakamura, Mamoo / Ruile, Philip / Deuschl, Florian / Berman, Daniel / Modine, Thomas / Ensminger, Stephan / Kornowski, Ran / Lange, Rudiger / McCabe, James M / Williams, Mathew R / Whisenant, Brian / Delgado, Victoria / Windecker, Stephan / Van Belle, Eric / Sondergaard, Lars / Chevalier, Bernard / Mack, Michael / Bax, Jeroen J / Leon, Martin B / Makkar, Raj R

Journal of the American College of Cardiology

2020 Volume 76, Issue 9, Page(s) 1018–1030

Abstract: Background: Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger ... ...

Abstract	Background: Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger populations will lead to increased use of TAVR for patients with bicuspid aortic valve (BAV) stenosis despite the exclusion of bicuspid anatomy in all pivotal clinical trials. Objectives: This study sought to evaluate the association of BAV morphology and outcomes of TAVR with the new-generation devices. Methods: Patients with BAV confirmed by central core laboratory computed tomography (CT) analysis were included from the international multicenter BAV TAVR registry. BAV morphology including the number of raphe, calcification grade in raphe, and leaflet calcium volume were assessed with CT analysis in a masked fashion. Primary outcomes were all-cause mortality at 1 and 2 years, and secondary outcomes included 30-day major endpoints and procedural complications. Results: A total of 1,034 CT-confirmed BAV patients with a mean age of 74.7 years and Society of Thoracic Surgeons score of 3.7% underwent TAVR with contemporary devices (n = 740 with Sapien 3; n = 188 with Evolut R/Pro; n = 106 with others). All-cause 30-day, 1-year, and 2-year mortality was 2.0%, 6.7%, and 12.5%, respectively. Multivariable analysis identified calcified raphe and excess leaflet calcification (defined as more than median calcium volume) as independent predictors of 2-year all-cause mortality. Both calcified raphe plus excess leaflet calcification were found in 269 patients (26.0%), and they had significantly higher 2-year all-cause mortality than those with 1 or none of these morphological features (25.7% vs. 9.5% vs. 5.9%; log-rank p < 0.001). Patients with both morphological features had higher rates of aortic root injury (p < 0.001), moderate-to-severe paravalvular regurgitation (p = 0.002), and 30-day mortality (p = 0.016). Conclusions: Outcomes of TAVR in bicuspid aortic stenosis depend on valve morphology. Calcified raphe and excess leaflet calcification were associated with increased risk of procedural complications and midterm mortality. (Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry; NCT03836521).
MeSH term(s)	Aged ; Aged, 80 and over ; Bicuspid Aortic Valve Disease/diagnostic imaging ; Bicuspid Aortic Valve Disease/mortality ; Bicuspid Aortic Valve Disease/surgery ; Female ; Follow-Up Studies ; Humans ; Internationality ; Male ; Mortality/trends ; Prospective Studies ; Registries ; Tomography, X-Ray Computed/mortality ; Tomography, X-Ray Computed/trends ; Transcatheter Aortic Valve Replacement/mortality ; Transcatheter Aortic Valve Replacement/trends ; Treatment Outcome
Language	English
Publishing date	2020-08-28
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2020.07.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

Order via subito

Details ▾

Article ; Online: Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement.

Yoon, Sung-Han / Bleiziffer, Sabine / Latib, Azeem / Eschenbach, Lena / Ancona, Marco / Vincent, Flavien / Kim, Won-Keun / Unbehaum, Axel / Asami, Masahiko / Dhoble, Abhijeet / Silaschi, Miriam / Frangieh, Antonio H / Veulemans, Verena / Tang, Gilbert H L / Kuwata, Shingo / Rampat, Rajiv / Schmidt, Tobias / Patel, Amisha J / Nicz, Pedro Felipe Gomez /

Nombela-Franco, Luis / Kini, Annapoorna / Kitamura, Mitsunobu / Sharma, Rahul / Chakravarty, Tarun / Hildick-Smith, David / Arnold, Martin / de Brito, Fabio Sandoli / Jensen, Christoph / Jung, Christian / Jilaihawi, Hasan / Smalling, Richard W / Maisano, Francesco / Kasel, Albert Markus / Treede, Hendrik / Kempfert, Joerg / Pilgrim, Thomas / Kar, Saibal / Bapat, Vinayak / Whisenant, Brian K / Van Belle, Eric / Delgado, Victoria / Modine, Thomas / Bax, Jeroen J / Makkar, Raj R

JACC. Cardiovascular interventions

2019 Volume 12, Issue 2, Page(s) 182–193

Abstract: Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR).: Background: LVOT obstruction is a major concern with TMVR, but limited data ... ...

Abstract	Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Background: LVOT obstruction is a major concern with TMVR, but limited data exist regarding its predictors and impact on outcomes. Methods: Patients with pre-procedural multidetector row computed tomography (MDCT) undergoing TMVR for failed mitral bioprosthetic valves (valve-in-valve), annuloplasty rings (valve-in-ring), and mitral annular calcification (valve-in-MAC) were included in this study. Echocardiographic and procedural characteristics were recorded, and comprehensive assessment with MDCT was performed to identify the predictors of LVOT obstruction (defined as an increment of mean LVOT gradient ≥10 mm Hg from baseline). The new LVOT (neo-LVOT) area left after TMVR was estimated by embedding a virtual valve into the mitral annulus on MDCT, simulating the procedure. Results: Among 194 patients with pre-procedural MDCT undergoing TMVR (valve-in-valve, 107 patients; valve-in-ring, 50 patients; valve-in-MAC, 37 patients), LVOT obstruction was observed in 26 patients (13.4%), with a higher rate after valve-in-MAC than valve-in-ring and valve-in-valve (54.1% vs. 8.0% vs. 1.9%; p < 0.001). Patients with LVOT obstruction had significantly higher procedural mortality compared with those without LVOT obstruction (34.6% vs. 2.4%; p < 0.001). Receiver-operating characteristic curve analysis showed that an estimated neo-LVOT area ≤1.7 cm Conclusions: LVOT obstruction after TMVR was associated with higher procedural mortality. A small estimated neo-LVOT area was significantly associated with LVOT obstruction after TMVR and may help identify patients at high risk for LVOT obstruction.
MeSH term(s)	Aged ; Aged, 80 and over ; Calcinosis/diagnostic imaging ; Calcinosis/mortality ; Calcinosis/physiopathology ; Calcinosis/surgery ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Cardiac Catheterization/mortality ; Echocardiography ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/instrumentation ; Heart Valve Prosthesis Implantation/mortality ; Humans ; Male ; Mitral Valve/diagnostic imaging ; Mitral Valve/physiopathology ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/mortality ; Mitral Valve Insufficiency/physiopathology ; Mitral Valve Insufficiency/surgery ; Mitral Valve Stenosis/diagnostic imaging ; Mitral Valve Stenosis/mortality ; Mitral Valve Stenosis/physiopathology ; Mitral Valve Stenosis/surgery ; Multidetector Computed Tomography ; Prosthesis Design ; Prosthesis Failure ; Registries ; Risk Assessment ; Risk Factors ; Treatment Outcome ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology ; Ventricular Outflow Obstruction/mortality ; Ventricular Outflow Obstruction/physiopathology
Language	English
Publishing date	2019-01-24
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2018.12.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6669: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings.

Yoon, Sung-Han / Whisenant, Brian K / Bleiziffer, Sabine / Delgado, Victoria / Schofer, Niklas / Eschenbach, Lena / Fujita, Buntaro / Sharma, Rahul / Ancona, Marco / Yzeiraj, Ermela / Cannata, Stefano / Barker, Colin / Davies, James E / Frangieh, Antonio H / Deuschl, Florian / Podlesnikar, Tomaz / Asami, Masahiko / Dhoble, Abhijeet / Chyou, Anthony /

Masson, Jean-Bernard / Wijeysundera, Harindra C / Blackman, Daniel J / Rampat, Rajiv / Taramasso, Maurizio / Gutierrez-Ibanes, Enrique / Chakravarty, Tarun / Attizzani, Guiherme F / Kaneko, Tsuyoshi / Wong, S Chiu / Sievert, Horst / Nietlispach, Fabian / Hildick-Smith, David / Nombela-Franco, Luis / Conradi, Lenard / Hengstenberg, Christian / Reardon, Michael J / Kasel, Albert Markus / Redwood, Simon / Colombo, Antonio / Kar, Saibal / Maisano, Francesco / Windecker, Stephan / Pilgrim, Thomas / Ensminger, Stephan M / Prendergast, Bernard D / Schofer, Joachim / Schaefer, Ulrich / Bax, Jeroen J / Latib, Azeem / Makkar, Raj R

Journal of the American College of Cardiology

2018 Volume 70, Issue 9, Page(s) 1121–1131

Abstract: Background: Limited data exist regarding transcatheter mitral valve replacement (TMVR) for patients with failed mitral valve replacement and repair.: Objectives: This study sought to evaluate the outcomes of TMVR in patients with failed mitral ... ...

Abstract	Background: Limited data exist regarding transcatheter mitral valve replacement (TMVR) for patients with failed mitral valve replacement and repair. Objectives: This study sought to evaluate the outcomes of TMVR in patients with failed mitral bioprosthetic valves (valve-in-valve [ViV]) and annuloplasty rings (valve-in-ring [ViR]). Methods: From the TMVR multicenter registry, procedural and clinical outcomes of mitral ViV and ViR were compared according to Mitral Valve Academic Research Consortium criteria. Results: A total of 248 patients with mean Society of Thoracic Surgeons score of 8.9 ± 6.8% underwent TMVR. Transseptal access and the balloon-expandable valve were used in 33.1% and 89.9%, respectively. Compared with 176 patients undergoing ViV, 72 patients undergoing ViR had lower left ventricular ejection fraction (45.6 ± 17.4% vs. 55.3 ± 11.1%; p < 0.001). Overall technical and device success rates were acceptable, at 92.3% and 85.5%, respectively. However, compared with the ViV group, the ViR group had lower technical success (83.3% vs. 96.0%; p = 0.001) due to more frequent second valve implantation (11.1% vs. 2.8%; p = 0.008), and lower device success (76.4% vs. 89.2%; p = 0.009) due to more frequent reintervention (16.7% vs. 7.4%; p = 0.03). Mean mitral valve gradients were similar between groups (6.4 ± 2.3 mm Hg vs. 5.8 ± 2.7 mm Hg; p = 0.17), whereas the ViR group had more frequent post-procedural mitral regurgitation moderate or higher (19.4% vs. 6.8%; p = 0.003). Furthermore, the ViR group had more frequent life-threatening bleeding (8.3% vs. 2.3%; p = 0.03), acute kidney injury (11.1% vs. 4.0%; p = 0.03), and subsequent lower procedural success (58.3% vs. 79.5%; p = 0.001). The 1-year all-cause mortality rate was significantly higher in the ViR group compared with the ViV group (28.7% vs. 12.6%; log-rank test, p = 0.01). On multivariable analysis, failed annuloplasty ring was independently associated with all-cause mortality (hazard ratio: 2.70; 95% confidence interval: 1.34 to 5.43; p = 0.005). Conclusions: The TMVR procedure provided acceptable outcomes in high-risk patients with degenerated bioprostheses or failed annuloplasty rings, but mitral ViR was associated with higher rates of procedural complications and mid-term mortality compared with mitral ViV.
MeSH term(s)	Aged ; Bioprosthesis/adverse effects ; Cardiac Catheterization/methods ; Europe/epidemiology ; Female ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation/methods ; Humans ; Male ; Mitral Valve/surgery ; Mitral Valve Annuloplasty/adverse effects ; North America/epidemiology ; Prosthesis Design ; Prosthesis Failure ; Reoperation ; Retrospective Studies ; Survival Rate/trends ; Treatment Outcome
Language	English
Publishing date	2018-05-18
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2017.07.714
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito