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  1. Article: Can Maintaining Optimal Magnesium Balance Reduce the Disease Severity of COVID-19 Patients?

    Eskander, Mark / Razzaque, Mohammed S

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 843152

    MeSH term(s) COVID-19 ; Humans ; Magnesium/therapeutic use ; Severity of Illness Index ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 2022-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.843152
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  2. Article: Alternating wide complex tachycardia after surgical aortic valve replacement.

    Darden, Douglas / Eskander, Michael / Feld, Gregory K

    Indian pacing and electrophysiology journal

    2021  Volume 21, Issue 3, Page(s) 191–195

    Abstract: A 51-year-old male developed recurrent episodes of palpitations and pre-syncope after surgical aortic valve replacement. Electrocardiograms after surgery revealed a wide complex tachycardia with alternating left bundle branch and right bundle branch ... ...

    Abstract A 51-year-old male developed recurrent episodes of palpitations and pre-syncope after surgical aortic valve replacement. Electrocardiograms after surgery revealed a wide complex tachycardia with alternating left bundle branch and right bundle branch block morphologies. An electrophysiology study (EPS) demonstrated typical bundle branch reentry ventricular tachycardia (BBRVT) treated successfully with right bundle ablation. We demonstrate the key diagnostic features of BBRVT on EPS, describe the circuit of BBRVT with explanation of the HV pseudointerval, and highlight the association of BBRVT and valve replacement.
    Language English
    Publishing date 2021-02-06
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2021.02.001
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  3. Article ; Online: Effect of phytic acid and ethylenediaminetetraacetic acid on penetration depth of bioceramic and resin sealers.

    Eskander, Mark / Genena, Salma / Zaazou, Ashraf / Moussa, Sybel

    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

    2021  Volume 47, Issue 3, Page(s) 506–511

    Abstract: This study assessed influence of 1% phytic acid and 17% ethylenediaminetetraacetic acid (EDTA) on the dentinal tubules penetration of EndoSequence BC bioceramic-based and AH Plus resin-based sealers using confocal laser scanning microscopy (CLSM). Forty ... ...

    Abstract This study assessed influence of 1% phytic acid and 17% ethylenediaminetetraacetic acid (EDTA) on the dentinal tubules penetration of EndoSequence BC bioceramic-based and AH Plus resin-based sealers using confocal laser scanning microscopy (CLSM). Forty single-rooted mandibular premolars were divided randomly into four groups (n = 10). Group 1 received final irrigation with 1% phytic acid solution and canals sealed by AH Plus sealer, Group 2: 1% phytic acid solution and EndoSequence BC sealer, Group 3: 17% EDTA solution and AH Plus sealer and Group 4: 17% EDTA solution and EndoSequence BC sealer. Specimens were horizontally sectioned 2, 4 and 6 mm from the apex. Average maximum depth of sealer penetration was examined using CLSM. Group three showed the deepest sealer penetration at all three levels which was significantly higher than all other groups (P ˂ 0.05). Deep sealer penetration is achievable with AH Plus and EDTA. Phytic acid groups have moderate tubular penetration ability.
    MeSH term(s) Edetic Acid ; Microscopy, Confocal ; Phytic Acid ; Dentin/chemistry ; Ceramics/chemistry ; Resin Cements/chemistry ; Bicuspid ; Humans ; Pit and Fissure Sealants/chemistry
    Chemical Substances Edetic Acid (9G34HU7RV0) ; Phytic Acid (7IGF0S7R8I) ; Resin Cements ; Pit and Fissure Sealants
    Language English
    Publishing date 2021-04-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2146484-4
    ISSN 1747-4477 ; 1329-1947
    ISSN (online) 1747-4477
    ISSN 1329-1947
    DOI 10.1111/aej.12513
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: The order of surgery and chemotherapy matters: Multimodality therapy and stage-specific differences in survival in gastric cancer.

    Ramos-Santillan, Vicente / Friedmann, Patricia / Eskander, Mariam / Chuy, Jennifer / Parides, Michael / In, Haejin

    Journal of surgical oncology

    2022  Volume 127, Issue 1, Page(s) 56–65

    Abstract: Background and objectives: Multimodality treatment improves survival for gastric cancer (GC). However, the effect of treatment sequence by stage remains unclear. We aim to compare outcomes between patients receiving neoadjuvant(neoadj) and adjuvant ... ...

    Abstract Background and objectives: Multimodality treatment improves survival for gastric cancer (GC). However, the effect of treatment sequence by stage remains unclear. We aim to compare outcomes between patients receiving neoadjuvant(neoadj) and adjuvant chemotherapy (adj).
    Methods: Nonmetastatic GC patients with clinical stage ≥ T2N0 who underwent both resection and neoadj or adj were identified using the National Cancer Database (2005-2014). Multivariable Cox regression analyses were performed on propensity score-matched (PSM) cohorts stratified by stage to compare overall survival (OS).
    Results: We identified 11 984 patients; 55% stage I (SI), 76% stage II (SII) and 57% stage III (SIII) received neoadj. Unadjusted analysis showed worse survival among SI neoadj patients (hazard ratio [HR] 1.195, confidence interval [CI] 1.04-1.38) and improved survival for SII (HR 0.93 CI 0.87-0.998) and SIII (HR 0.75, CI 0.68-0.84). After PSM, SI patients with neoadj had worse OS with increased risk of death compared to Adj (HR 1.186, CI 1.004-1.402). SII patients had no difference in OS (HR 0.98, CI 0.91-1.07) and SIII patients had improved OS (HR 0.78, CI 0.69-0.90).
    Conclusions: In patients who received surgery and chemotherapy, the benefit of neoadj was limited to SIII with worse survival for SI. A clinical trial to examine the optimal sequence of chemotherapy is warranted.
    MeSH term(s) Humans ; Stomach Neoplasms/therapy ; Stomach Neoplasms/pathology ; Neoplasm Staging ; Combined Modality Therapy ; Chemotherapy, Adjuvant ; Proportional Hazards Models
    Language English
    Publishing date 2022-10-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.27110
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 706: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Implantable loop recorder as a strategy following cardiovascular implantable electronic device extraction without reimplantation.

    Birs, Antoinette / Darden, Douglas / Eskander, Michael / Pollema, Travis / Ho, Gordon / Birgersdotter-Green, Ulrika

    Pacing and clinical electrophysiology : PACE

    2022  Volume 45, Issue 7, Page(s) 853–860

    Abstract: Background: Limited data exists for outcomes in patients undergoing cardiovascular implantable electronic device (CIED) transvenous lead extraction (TLE) without clear indications for device reimplantation. The implantable loop recorder (ILR) may be an ... ...

    Abstract Background: Limited data exists for outcomes in patients undergoing cardiovascular implantable electronic device (CIED) transvenous lead extraction (TLE) without clear indications for device reimplantation. The implantable loop recorder (ILR) may be an effective strategy for continuous monitoring in select individuals.
    Objective: This retrospective analysis aims to investigate patients who have undergone ILR implant following TLE without CIED reimplantation.
    Methods: Clinical data from consecutive patients who have undergone TLE with ILR implant and without CIED reimplantation from October 2016 to May 2020 at a single center were collected.
    Results: Among 380 patients undergoing TLE, 28 (7.7%) underwent ILR placement without CIED reimplantation. TLE indications were systemic infection (n = 13, 46.4%), pain at the site (n = 8, 28.6%), device/lead malfunction (n = 4, 14.2%), and other. Devices extracted included: dual-chamber and single-chamber pacemaker (n = 14, 50%; n = 4, 14.2%), dual-chamber implantable cardiac defibrillator (n = 10; 35.7%), and cardiac-resynchronization therapy with defibrillator (n = 1, 3.5%). Reasons for no reimplantation included no longer meeting CIED criteria (n = 14, 50%), patient preference (n = 9, 32.1%), and no clear or inappropriate indication for initial CIED implantation (n = 5, 18%). During an average of 12.3 ± 13.1 months of follow-up, there were no lethal arrhythmias, and four (13.3%) patients underwent permanent pacemaker reimplantation due to symptomatic sinus bradycardia and atrioventricular block with syncope as discovered on ILR. Three patients died due to unknown causes (n = 1), noncardiac (n = 1), and acute coronary syndrome (n = 1).
    Conclusions: In patients undergoing TLE without reimplantation, an ILR may be an effective monitoring strategy in patients at low risk for cardiac arrhythmia.
    MeSH term(s) Arrhythmias, Cardiac/therapy ; Defibrillators, Implantable/adverse effects ; Electronics ; Humans ; Pacemaker, Artificial/adverse effects ; Retrospective Studies
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14519
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1466: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 399: Show issues

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  6. Article ; Online: Invasive Hemodynamics of Myocardial Disease: Systolic and Diastolic Dysfunction (and Hypertrophic Obstructive Cardiomyopathy).

    Eskander, Michael / Kern, Morton J

    Interventional cardiology clinics

    2017  Volume 6, Issue 3, Page(s) 297–307

    Abstract: Heart failure is a clinical diagnosis that is supported by various laboratory, imaging, and invasive hemodynamic measures. There is no single diagnostic test. A variety of structural and/or functional myocardial abnormalities can lead to the inability of ...

    Abstract Heart failure is a clinical diagnosis that is supported by various laboratory, imaging, and invasive hemodynamic measures. There is no single diagnostic test. A variety of structural and/or functional myocardial abnormalities can lead to the inability of the heart to fill or eject blood. Despite ejection fraction being the most commonly assessed measure of systolic function in clinical practice, it is a poor measure of contractility because it is susceptible to loading conditions and chamber size. Invasive hemodynamic assessment remains of great importance in the evaluation of patients with myocardial disease or hypertrophic cardiomyopathy.
    MeSH term(s) Cardiomyopathy, Hypertrophic/diagnosis ; Cardiomyopathy, Hypertrophic/physiopathology ; Diastole ; Humans ; Monitoring, Physiologic/methods ; Myocardial Contraction/physiology ; Systole ; Ventricular Function/physiology
    Language English
    Publishing date 2017-04-21
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2017.03.001
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  7. Article ; Online: Differentiation of Cells Isolated from Human Femoral Heads into Functional Osteoclasts.

    Halloran, Daniel R / Heubel, Brian / MacMurray, Connor / Root, Denise / Eskander, Mark / McTague, Sean P / Pelkey, Heather / Nohe, Anja

    Journal of developmental biology

    2022  Volume 10, Issue 1

    Abstract: Proper formation of the skeleton during development is crucial for the mobility of humans and the maintenance of essential organs. The production of bone is regulated by osteoblasts and osteoclasts. An imbalance of these cells can lead to a decrease in ... ...

    Abstract Proper formation of the skeleton during development is crucial for the mobility of humans and the maintenance of essential organs. The production of bone is regulated by osteoblasts and osteoclasts. An imbalance of these cells can lead to a decrease in bone mineral density, which leads to fractures. While many studies are emerging to understand the role of osteoblasts, less studies are present about the role of osteoclasts. This present study utilized bone marrow cells isolated directly from the bone marrow of femoral heads obtained from osteoarthritic (OA) patients after undergoing hip replacement surgery. Here, we used tartrate resistant acid phosphatase (TRAP) staining, Cathepsin K, and nuclei to identity osteoclasts and their functionality after stimulation with macrophage-colony stimulation factor (M-CSF) and receptor activator of nuclear factor kappa-β ligand (RANKL). Our data demonstrated that isolated cells can be differentiated into functional osteoclasts, as indicated by the 92% and 83% of cells that stained positive for TRAP and Cathepsin K, respectively. Furthermore, isolated cells remain viable and terminally differentiate into osteoclasts when stimulated with RANKL. These data demonstrate that cells isolated from human femoral heads can be differentiated into osteoclasts to study bone disorders during development and adulthood.
    Language English
    Publishing date 2022-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720870-9
    ISSN 2221-3759 ; 2221-3759
    ISSN (online) 2221-3759
    ISSN 2221-3759
    DOI 10.3390/jdb10010006
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  8. Article ; Online: Factors predicting successful sperm retrieval in men with nonobstructive Azoospermia: A single center perspective.

    Aljubran, Abdulkareem / Safar, Omar / Elatreisy, Adel / Alwadai, Raed / Shalkamy, Osama / Assiri, Hassan Mohammed / Eskander, Mamdoh / Arezki, Adel / Ibrahim, Ahmed

    Health science reports

    2022  Volume 5, Issue 4, Page(s) e727

    Abstract: Predicting successful sperm retrieval is essential in counseling infertile men with Azoospermia.: Objectives: To assess the predictors of successful sperm extraction in men with nonobstructive Azoospermia.: Patients and methods: A retrospective ... ...

    Abstract Predicting successful sperm retrieval is essential in counseling infertile men with Azoospermia.
    Objectives: To assess the predictors of successful sperm extraction in men with nonobstructive Azoospermia.
    Patients and methods: A retrospective study included all patients with nonobstructive Azoospermia from January 2018 to May 2019. Subdivided into two groups, group I (negative sperm retrieval) and group II (positive sperm retrieval).
    Results: A total of 108 patients with a mean age of 36.8 ± 10 years were included. The rate of successful sperm retrieval was 47.2%. Group I included 57 patients (52.8%) with a mean age of 33.98 ± 6.18, and group II included 51 patients (47.2%) with a mean age of 40.04 ± 12.22 (
    Conclusion: Patients' age and serum FSH are independent predictors of successful sperm retrieval for infertile men with nonobstructive Azoospermia; young patients with high FSH levels could have little chance of sperm retrieval.
    Language English
    Publishing date 2022-07-21
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.727
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  9. Article: Estimating the Prevalence of Foodborne Pathogen

    Hamad, Gamal M / Gerges, Mariam / Mehany, Taha / Hussein, Saleh M / Eskander, Michael / Tawfik, Rasha G / El-Halmouch, Yasser / Mansour, Alaa M / Hafez, Elsayed E / Esatbeyoglu, Tuba / Elghazaly, Eman M

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 7

    Abstract: Campylobacter ... ...

    Abstract Campylobacter jejuni
    Language English
    Publishing date 2023-07-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12070958
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  10. Article: Detection of

    Hamad, Gamal / Hafez, Elsayed E / Sobhy, Sherien E / Mehany, Taha / Elfayoumy, Reham A / Elghazaly, Eman M / Eskander, Michael / Tawfik, Rasha G / Hussein, Saleh M / Pereira, Leonel

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 7

    Abstract: This study aims to ... ...

    Abstract This study aims to detect
    Language English
    Publishing date 2023-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12071466
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