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  1. Article ; Online: Prehospital blood transfusion for haemorrhagic shock.

    Cardinale, Michael / Mathais, Quentin / Esnault, Pierre / Cotte, Jean

    The Lancet. Haematology

    2022  Volume 9, Issue 6, Page(s) e395

    MeSH term(s) Blood Transfusion ; Emergency Medical Services ; Humans ; Shock, Hemorrhagic/therapy
    Language English
    Publishing date 2022-05-26
    Publishing country England
    Document type Letter ; Comment
    ISSN 2352-3026
    ISSN (online) 2352-3026
    DOI 10.1016/S2352-3026(22)00115-6
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  2. Article ; Online: Assessment of Airway Closure and Expiratory Airflow Limitation to Set Positive End-Expiratory Pressure in Morbidly Obese Patients with Acute Respiratory Distress Syndrome.

    Mezidi, Mehdi / Esnault, Pierre / Hraiech, Sami / Guervilly, Christophe

    American journal of respiratory and critical care medicine

    2022  Volume 203, Issue 3, Page(s) 391–392

    MeSH term(s) Hemodynamics ; Humans ; Obesity, Morbid/complications ; Positive-Pressure Respiration ; Pulmonary Ventilation ; Respiratory Distress Syndrome/therapy
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202009-3477LE
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  3. Article: Reversible Cerebral Vasoconstriction Syndrome Treated by Continuous Intravenous Milrinone

    de Malleray, Hilaire / Gazzola, Sebastien / Meaudre, Eric / Esnault, Pierre

    Journal of Neuroanaesthesiology and Critical Care

    2023  Volume 10, Issue 01, Page(s) 69–71

    Language English
    Publishing date 2023-03-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2937287-2
    ISSN 2348-926X ; 2348-0548
    ISSN (online) 2348-926X
    ISSN 2348-0548
    DOI 10.1055/s-0043-1761248
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  4. Article ; Online: Management of intracranial hypertension in patients with severe traumatic brain injury: Pay attention to the oxygen level.

    Esnault, Pierre / Sartre, Milena / Cardinale, Mickaël / Meaudre, Eric

    The journal of trauma and acute care surgery

    2020  Volume 88, Issue 6, Page(s) e153

    MeSH term(s) Attention ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/therapy ; Humans ; Intracranial Hypertension/etiology ; Intracranial Hypertension/therapy ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2651070-4
    ISSN 2163-0763 ; 2163-0755
    ISSN (online) 2163-0763
    ISSN 2163-0755
    DOI 10.1097/TA.0000000000002630
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  5. Article ; Online: Severe Trauma Patients Requiring Undelayable Combined Cranial and Extra-Cranial Surgery: A Proof-of-Concept Monocentric Study.

    Beucler, Nathan / Sellier, Aurore / Joubert, Christophe / Bernard, Cédric / Desse, Nicolas / Esnault, Pierre / Dagain, Arnaud

    Military medicine

    2022  Volume 187, Issue 9-10, Page(s) 1127–1135

    Abstract: Introduction: To date, there is no evidence concerning the emergency surgical management of severe trauma patients (STP) with severe traumatic brain injury (STBI) presenting a life-threatening intracranial hematoma and a concomitant extra-cranial ... ...

    Abstract Introduction: To date, there is no evidence concerning the emergency surgical management of severe trauma patients (STP) with severe traumatic brain injury (STBI) presenting a life-threatening intracranial hematoma and a concomitant extra-cranial noncompressible active bleeding. Current guidelines recommend stopping the extra-cranial bleeding first. Nevertheless, the long-term outcome of STP with STBI mainly depends from intracranial lesions. Thus, we propose a combined damage-control surgical strategy aiming to reduce the time spent with intracranial hypertension and to hasten the admission in the intensive care unit. The main objective of the study is to evaluate the benefits of combined cranial and extra-cranial surgery of STP on the long-term outcome.
    Materials and methods: We retrospectively searched through the database of STBI of a level 1 trauma center facility (Sainte-Anne Military Teaching Hospital, Toulon, France) from 2007 until 2021 looking for patients who benefited from combined cranial and extra-cranial surgery in an acute setting.
    Results: The research yielded 8 patients. The mean age was 35 years old (±14) and the male to female sex ratio was 1.7/1. The trauma mechanism was a fall in 50% of the cases and a traffic accident in 50% of the cases. The median Glasgow coma scale score was 8 (IQR 4) before intubation. The median Injury Severity Score was 41 (IQR 16). Seven patients (88%) presented hypovolemic shock upon admission. Six patients (75%) benefited from damage-control laparotomy among, whom 4 (67%) underwent hemostatic splenectomy. One patient benefited from drainage of tension pneumothorax, and one patient benefited from external fixator of multiple limb fractures. Seven patients (88%) benefited from decompressive craniectomy for acute subdural hematoma (5 patients) or major brain contusion (2 patients). One patient (12%) benefited from craniotomy for epidural hematoma. Three patients presented intraoperative profound hypovolemic shock. Six patients (75%) presented a favorable neurologic outcome with minor complications from extra-cranial surgeries and 2 patients died (25%).
    Conclusion: Performing combined life-saving cranial and extra-cranial surgery is feasible and safe as long as the trauma teams are trained according to the principles of damage control. It may be beneficial for the neurologic prognostic of STP with STBI requiring cranial and extra-cranial surgery.
    MeSH term(s) Adult ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/surgery ; Craniotomy/adverse effects ; Female ; Glasgow Coma Scale ; Hematoma, Epidural, Cranial/etiology ; Hematoma, Epidural, Cranial/surgery ; Humans ; Intracranial Hypertension/etiology ; Male ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-01-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usab555
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  6. Article ; Online: Transient Left Ventricular Acute Failure after Cocaine Use.

    Cardinale, Michaël / Esnault, Pierre / Schmitt, Johan / Meaudre, Eric

    Current drug research reviews

    2019  Volume 11, Issue 2, Page(s) 142–144

    Abstract: Background: Cocaine is one of the most widely used illicit drugs, and it is the most common cause of drug-related death. The association of cocaine use with acute heart failure is a rare occurrence.: Case report: We report the case of a 31 years-old ... ...

    Abstract Background: Cocaine is one of the most widely used illicit drugs, and it is the most common cause of drug-related death. The association of cocaine use with acute heart failure is a rare occurrence.
    Case report: We report the case of a 31 years-old woman who presented Takotsubo cardiomyopathy with severe cardiogenic shock after cocaine abuse. That required the use of high doses of positive inotropic amines and mechanical ventilation. The evolution was quickly favorable after the cessation of cocaine.
    Discussion: Takotsubo cardiomyopathy is often related to a stressful trigger, and several cases have been described with the use of several psychostimulants. As such, it is not surprising that cocaine use can be associated with the development of Takotsubo cardiomyopathy when it results in excess release of catecholamines and excitation of adrenergic receptors.
    Conclusion: In critical care unit, Takotsubo cardiomyopathy is a rare complication of cocaine abuse. This etiological diagnosis can be difficult especially in the absence of the concept of toxic intake as it was initially the case for our patient, but the treatment does not differ from other causes of cardiomyopathy and Cessation of cocaine use has been associated with improvement in cardiac function.
    MeSH term(s) Adult ; Cardiotonic Agents/therapeutic use ; Cocaine/adverse effects ; Cocaine-Related Disorders/complications ; Echocardiography ; Electrocardiography ; Female ; Humans ; Respiration, Artificial ; Shock, Cardiogenic/chemically induced ; Shock, Cardiogenic/diagnostic imaging ; Shock, Cardiogenic/drug therapy ; Takotsubo Cardiomyopathy/chemically induced ; Takotsubo Cardiomyopathy/diagnostic imaging ; Takotsubo Cardiomyopathy/drug therapy ; Treatment Outcome ; Ventricular Dysfunction, Left/chemically induced ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/drug therapy
    Chemical Substances Cardiotonic Agents ; Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2019-07-22
    Publishing country United Arab Emirates
    Document type Case Reports
    ISSN 2589-9783
    ISSN (online) 2589-9783
    DOI 10.2174/2589977511666190716111303
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  7. Article ; Online: Reply to:

    Cardinale, Michael / Cungi, Pierre-Julien / Esnault, Pierre / Meaudre, Eric / Goutorbe, Philippe

    Respiratory care

    2021  Volume 66, Issue 8, Page(s) 1369–1370

    MeSH term(s) Humans ; Noninvasive Ventilation ; Pulmonary Disease, Chronic Obstructive/therapy ; Respiration, Artificial ; Respiratory Distress Syndrome
    Language English
    Publishing date 2021-07-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.09172
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  8. Article: Severe Aortic Thrombosis and Profound Hypothermia: A Case Report.

    Schmitt, Johan / Esnault, Pierre / Sartre, Milena / Cungi, Pierre J / Meaudre, Eric

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2021  Volume 25, Issue 5, Page(s) 588–589

    Abstract: Background: Blood clot formation is a multifactorial process and has been related many times in intensive care units. Here is presented a multiple thrombosis formation in a rewarming patient.: Case description: A 68-year-old patient was admitted to ... ...

    Abstract Background: Blood clot formation is a multifactorial process and has been related many times in intensive care units. Here is presented a multiple thrombosis formation in a rewarming patient.
    Case description: A 68-year-old patient was admitted to our intensive care unit after lying on the floor for an unknown time. She presented a severe hypothermia at 26° and a severe cardiogenic shock. Because she was confused and was hypoxemic, she had been intubated at her admission. After intravascular warming, we could stop sedative medications. She presented a right hemiparesis and acute left leg ischemia. Computed tomography (CT) scan revealed a constituted left Sylvian stroke and a massive clot along the aorta. She required a surgical embolectomy and fasciotomy. She died after she presented a severe bowel ischemia on the third day after her admission.
    Conclusion: Relevant hypothesis for blood clot formation in this patient may include prolonged lying position or blood temperature variation. Hypothermia and rewarming responsibilities may explain multiple thrombosis development.
    How to cite this article: Schmitt J, Esnault P, Sartre M, Cungi PJ, Meaudre E. Severe Aortic Thrombosis and Profound Hypothermia: A Case Report. Indian J Crit Care Med 2021;25(5):588-589.
    Language English
    Publishing date 2021-06-10
    Publishing country India
    Document type Case Reports
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23820
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  9. Article ; Online: Sudden intracerebral aneurysm rupture during endovascular coiling.

    Mathais, Quentin / Esnault, Pierre / Montcriol, Ambroise / Contargyris, Claire

    Acta neurochirurgica

    2018  Volume 160, Issue 12, Page(s) 2409–2410

    Language English
    Publishing date 2018-10-26
    Publishing country Austria
    Document type Letter
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-018-3703-9
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  10. Article ; Online: Lung-Dependent Areas Collapse, Monitored by Electrical Impedance Tomography, May Predict the Oxygenation Response to Prone Ventilation in COVID-19 Acute Respiratory Distress Syndrome.

    Cardinale, Michael / Boussen, Salah / Cungi, Pierre-Julien / Esnault, Pierre / Mathais, Quentin / Bordes, Julien / Meaudre, Eric / Goutorbe, Philippe

    Critical care medicine

    2022  Volume 50, Issue 7, Page(s) 1093–1102

    Abstract: Objectives: ICUs have had to deal with a large number of patients with acute respiratory distress syndrome COVID-19, a significant number of whom received prone ventilation, which is a substantial consumer of care time. The selection of patients that we ...

    Abstract Objectives: ICUs have had to deal with a large number of patients with acute respiratory distress syndrome COVID-19, a significant number of whom received prone ventilation, which is a substantial consumer of care time. The selection of patients that we have to ventilate in prone position seems interesting. We evaluate the correlation between the percentage of collapsed dependent lung areas in the supine position, monitoring by electrical impedance tomography and the oxygenation response (change in Pao2/Fio2 ratio) to prone position.
    Design: An observational prospective study.
    Setting: From October 21, 2020, to 30 March 30, 2021. At the Sainte Anne military teaching Hospital and the Timone University Hospital.
    Patients: Fifty consecutive patients admitted in our ICUs, with COVID-19 acute respiratory distress syndrome and required mechanical, were included. Twenty-four (48%) received prone ventilation. Fifty-eight prone sessions were investigated.
    Interventions: An electrical impedance tomography recording was made in supine position, daily and repeated just before and just after the prone session. The daily dependent area collapse was calculated in relation to the previous electrical impedance tomography recording. Prone ventilation response was defined as a Pao2/Fio2 ratio improvement greater than 20%.
    Measurement and main results: The main outcome was the correlation between dependent area collapse and the oxygenation response to prone ventilation. Dependent area collapse was correlated with oxygenation response to prone ventilation (R2 = 0.49) and had a satisfactory prediction accuracy of prone response with an area under the curve of 0.94 (95% CI, 0.87-1.00; p < 0.001). Best Youden index was obtained for a dependent area collapse greater than 13.5 %. Sensitivity of 92% (95% CI, 78-97), a specificity of 91% (95% CI, 72-97), a positive predictive value of 94% (95% CI, 88-100), a negative predictive value of 87% (95% CI, 78-96), and a diagnostic accuracy of 91% (95% CI, 84-98).
    Conclusions: Dependent lung areas collapse (> 13.5%), monitored by electrical impedance tomography, has an excellent positive predictive value (94%) of improved oxygenation during prone ventilation.
    MeSH term(s) COVID-19/therapy ; Electric Impedance ; Humans ; Lung/diagnostic imaging ; Prone Position ; Prospective Studies ; Respiratory Distress Syndrome/therapy ; Shock ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-02-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005487
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