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Article: Tongue Spindle Cell Rhabdomyosarcoma: A Rare Case Report and Literature Review.

Jariod-Ferrer, Ursula M / Trigo-Cebrian, Miguel Angel / Pantilie, Bianca / Simon Sanz, María V / Esparza Lasaga, Leire / Gavin-Clavero, Marina A / Delso-Gil, Elena / Martinez-Trufero, Javier

Journal of maxillofacial and oral surgery

2020  Volume 20, Issue 3, Page(s) 464–469

Abstract: Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm with its origin in the skeletal muscle and is extremely rare in adults. By the World Health Organization (WHO), a new variant of RMS has been classified, i.e. the spindle cell (Sc) and sclerosing ...

Abstract Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm with its origin in the skeletal muscle and is extremely rare in adults. By the World Health Organization (WHO), a new variant of RMS has been classified, i.e. the spindle cell (Sc) and sclerosing (S) RMS. While the Sc-RMS shows intersecting fascicles of nonpleomorphic spindle cells, the S-RMS is characterized by a marked hyalinization in a pseudovascular growth pattern associated with round-to-spindled tumour cells. According to the analysed data, the Sc/S-RMS variant has a worse outcome than other variants. The new classification of the Sc/S-RMS variant is valuable to the clinical practice. There are not many oral Sc/S-RMS cases reported. The aim of this paper is to demonstrate that an early diagnosis, an adequate treatment and a multidisciplinary approach have a positive effect on the prognosis of the patient. In this study, we analyse a new case of Sc-RMS variant in a young adult with an early diagnosis and a favourable outcome as a result of an appropriated multidisciplinary treatment: early surgery, radiotherapy and chemotherapy treatment.
Language English
Publishing date 2020-09-26
Publishing country India
Document type Case Reports
ZDB-ID 2502352-4
ISSN 0974-942X ; 0972-8279
ISSN (online) 0974-942X
ISSN 0972-8279
DOI 10.1007/s12663-020-01447-3
Database MEDical Literature Analysis and Retrieval System OnLINE

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