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  1. Article: Routine systematic prostate biopsies not replaced by magnetic resonance imaging-targeted biopsy.

    Gómez-Ortiz, David / Garza-Gangemi, Adrián M / Oropeza-Aguilar, Mariano / Rangel-Suárez, Sergio / Espinosa-Cruz, Verónica / Villegas-Hernández, Antonio C / Martínez-Martínez, Ricardo / Castillejos-Molina, Ricardo A

    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

    2022  Volume 74, Issue 4, Page(s) 212–218

    Abstract: Background: Multiparametric magnetic resonance imaging improves the performance of prostate cancer (PCa) diagnostics through a better selection of patients.: Objectives: The aim of the study was to study the detection rate (DR) of systematic and ... ...

    Abstract Background: Multiparametric magnetic resonance imaging improves the performance of prostate cancer (PCa) diagnostics through a better selection of patients.
    Objectives: The aim of the study was to study the detection rate (DR) of systematic and targeted cognitive biopsies in a cohort with the previous negative systematic biopsies. A secondary objective was to describe the value of prostate-specific antigen density (PSAd) in the detection of clinically significant PCa (CSPCa).
    Methods: We designed a prospective, single-center, and comparative study to determine the DR of systematic and targeted cognitive biopsies. The clinical and pathological characteristics of each patient were described.
    Results: A total of 111 patients with Prostate Imaging Reporting and Data System lesions > 3 were included in the study. PCa was detected in 41.4% (46 of 111 patients); 42 (91.3%) were detected by systematic biopsy and 30 (65.2%) by targeted biopsy. CSPCa was detected in 26 (23.4%), 23 (88.5%) by systematic biopsy, and 21 (76.9%) by targeted biopsy. PSAd > 0.15 was directly associated with CSPCa.
    Conclusion: The detection of PCa by systematic biopsy in this series was higher than 80%; hence, its routine use should not be replaced by targeted biopsy, since it continues to be the cornerstone of the diagnosis in patients with prior negative biopsies.
    MeSH term(s) Biopsy ; Humans ; Image-Guided Biopsy/methods ; Magnetic Resonance Imaging/methods ; Male ; Prospective Studies ; Prostate/diagnostic imaging ; Prostate/pathology ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology
    Language English
    Publishing date 2022-07-01
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 138348-6
    ISSN 0034-8376
    ISSN 0034-8376
    DOI 10.24875/RIC.22000084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 288: Show issues Location:
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  2. Article ; Online: Bilateral Proximal Forearm Transplantation: Case Report at 7 Years.

    Iglesias, Martín / Villanueva-Castro, Eliezer / Macias-Gallardo, Julio / Alberú-Gómez, Josefina / Leal-Villalpando, Rafael P / Zamudio-Bautista, Jorge / Acosta, Victor / Butrón, Patricia / Sierra-Madero, Juan G / Cuellar-Rodriguez, Jennifer / Espinosa-Cruz, Verónica / Gómez-Camargo, Claudia / Mayorquín-Ruiz, Mariana / Vázquez-Lamadrid, Jorge / Toussaint-Caire, Sonia / Domínguez-Cherit, Judith / Dorantes-García, Joel / Furuzawa-Carballeda, Janette / Hernandez-Castillo, Carlos R /
    Guzmán González, Juan M / Castelan-Carmona, Natalia / López-Mártinez, Mayra / González-Tableros, Norma / Arvizu-Hernández, Adriana / De Santiago-Zárate, Adrián

    Transplantation

    2020  Volume 104, Issue 4, Page(s) e90–e97

    Abstract: Background: Although return of function has been reported in patients undergoing proximal forearm transplantations (PFTs), reports of long-term function are limited. In this study, we evaluated the clinical progress and function 7 years postoperatively ... ...

    Abstract Background: Although return of function has been reported in patients undergoing proximal forearm transplantations (PFTs), reports of long-term function are limited. In this study, we evaluated the clinical progress and function 7 years postoperatively in a patient who underwent bilateral PFT.
    Case presentation: A 58-year-old man underwent bilateral PFT in May 2012. Transplantation involved all of the flexor and extensor muscles of the forearm. Neurorrhaphies of the median, ulnar, and radial nerves were epineural and 7 cm proximal to the elbow. Immunosuppressive maintenance medications during the first 3 years postoperatively were tacrolimus, mycophenolate, and steroids, and later, tacrolimus, sirolimus, and steroids. Forearm function was evaluated annually using the Disabilities of the Arm, Shoulder, and Hand; Carroll; Hand Transplantation Score System; Short Form-36; and Kapandji scales. We also evaluated his grip and pinch force.
    Results: Postoperatively, the patient developed hypertriglyceridemia and systemic hypertension. He experienced 6 acute rejections, and none were resistant to steroids. Motor function findings in his right/left hand were: grip strength: 10/13 kg; key pinch: 3/3 kg; Kapandji score: 6/9 of 10; Carroll score: 66/80; Hand Transplantation Score System score: 90/94. His preoperative Disabilities of the Arm, Shoulder, and Hand score was 50 versus 18, postoperatively; his Short Form-36 score was 90. This function improved in relation with the function reported in the second year.
    Conclusions: Seven years following PFT, the patient gained limb strength with a functional elbow and wrist, although with diminished digital dexterity and sensation. Based on data presented by other programs and our own experience, PFT is indicated for select patients.
    MeSH term(s) Disability Evaluation ; Forearm/innervation ; Forearm/surgery ; Graft Rejection/drug therapy ; Graft Rejection/immunology ; Graft Survival ; Humans ; Immunosuppressive Agents/administration & dosage ; Male ; Middle Aged ; Motor Activity ; Muscle Strength ; Organ Transplantation ; Recovery of Function ; Sensation ; Time Factors ; Treatment Outcome
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2020-01-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
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    Zs.MO 509: Show issues

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  3. Article: Anatomical and Microsurgical Implications in Total and Midarm Transplantation

    Iglesias, Martin / Salazar-Hernández, Fernanda / Ramírez-Berumen, María F. / Butrón, Patricia / Alberú-Gómez, Josefina / Leal-Villalpando, Rafael P. / Zamudio-Bautista, Jorge / Acosta, Victor / Jauregui-Flores, Luis A. / Espinosa-Cruz, Verónica / Vázquez-Lamadrid, Jorge / González-Sánchez, Judith / Hinojosa, Carlos A. / Laparra-Escareño, Hugo / Montejo-Vargas, Juan / Macias-Gallardo, Julio

    Journal of Reconstructive Microsurgery Open

    2017  Volume 02, Issue 02, Page(s) e94–e102

    Abstract: Background: Arm transplantations are performed less frequently than forearm and hand transplantations. We present the surgical and microsurgical technique and its relationship with the clinical results in a patient with bilateral arm transplantation. !## ...

    Abstract Background: Arm transplantations are performed less frequently than forearm and hand transplantations. We present the surgical and microsurgical technique and its relationship with the clinical results in a patient with bilateral arm transplantation.
    Methods: A 51-year-old male patient underwent bilateral arm transplantation in October 2015. The right arm was transplanted at the glenohumeral joint. The vascular repair was at the axillary level, and the nerves were repaired at their origin. The total ischemia time was 3 hours and 48 minutes. The left arm was transplanted at the midhumeral level; all muscles were completely transplanted. The nerves were repaired at the distal third of the arm. Additionally, terminolateral neurorrhaphy was performed from the donor musculocutaneous nerve to the recipient radial nerve. The total ischemia time was 6 hours and 35 minutes.
    Results: At 15 months posttransplantation, the right shoulder had an abduction of 90 degrees and muscle strength of M4; flexion of 100 degrees and M4; internal and external rotation of M1; elbow flexion of 120 degrees and M3; elbow extension of M5; pronosupination of M2; and wrist extension of M2. There was no mobility in the fingers. The left transplanted limb had total elbow flexion and extension of M5, pronosupination of M2, wrist extension of M4, and finger flexion of M2. Both extremities had thermal sensitivity that allowed discrimination of cold and heat with residual deep pressure.
    Conclusion: Although the functional results of arm transplantation are so far unknown, they may be considered beneficial compared with the devastating disability caused by arm amputation.
    Keywords arm transplantation ; vascularized composite allotransplantation ; hand transplantation
    Language English
    Publishing date 2017-07-01
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2863089-0
    ISSN 2377-0821 ; 2377-0813
    ISSN (online) 2377-0821
    ISSN 2377-0813
    DOI 10.1055/s-0037-1604342
    Database Thieme publisher's database

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    Zs.A 7099: Show issues Location:
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  4. Article ; Online: Bilateral Forearm Transplantation in Mexico: 2-Year Outcomes.

    Iglesias, Martin / Butron, Patricia / Moran-Romero, Mario / Cruz-Reyes, Angel / Alberu-Gomez, Josefina / Leal-Villalpando, Paulino / Bautista-Zamudio, Jorge / Ramirez-Berumen, Maria / Lara-Hinojosa, Euridice / Espinosa-Cruz, Veronica / Gaytan-Cervantes, Rocio / Bravo-Ruiz, Leonardo / Rodriguez-Rojas, Elizabeth / Ramos-Peek, Jaime / Garcia-Alvarez, Miriam / Vega-Boada, Felipe / Sierra-Madero, Juan / Gamboa-Dominguez, Armando / Gonzalez-Sanchez, Judith /
    Contreras-Barbosa, Sarai / Navarro-Lara, Africa / Vazquez-Lamadrid, Jorge / Guzman-Gonzalez, Juan

    Transplantation

    2016  Volume 100, Issue 1, Page(s) 233–238

    Abstract: Background: Patients with proximal forearm and arm transplantation have obtained and/or maintained function of the elbow joint and full active range of motion of the extrinsic muscles of the hand, but with diminished protective sensibility and a lack of ...

    Abstract Background: Patients with proximal forearm and arm transplantation have obtained and/or maintained function of the elbow joint and full active range of motion of the extrinsic muscles of the hand, but with diminished protective sensibility and a lack of good function of the intrinsic muscles. These patients have improved function, as measured by the Disabilities of the Arm, Shoulder and Hand questionnaire.
    Methods: We report the case of a 52-year-old man who suffered a high-voltage electrical burn requiring amputation of his upper limbs. He underwent bilateral proximal forearm transplantation in Mexico City in May 2012.
    Results: At 2-year follow-up, immunosuppressive treatment has not led to metabolic, oncologic, or infectious complications. Keloid scars developed at the graft-recipient interface. There have been 4 acute rejections: the fourth was treated with methylprednisolone, rituximab, and immunoglobulin. Chronic rejection has not been detected. The extrinsic muscles of the wrist and digits have good function. Although the intrinsic muscles demonstrated electrical activity 15 months postoperatively, clinically, they are nonuseful. After 2 years, hand function is sufficient to allow the patient to grasp lightweight and medium-sized objects. The patient's Disabilities of the Arm, Shoulder and Hand questionnaire score improved from 50.00 points to 30.83 points, and his Hand Transplantation Score System rating is good, at 69/73 (right/left) of 100. The patient and his family are very satisfied with the functional and aesthetic outcomes.
    Conclusions: Upper arm or proximal forearm transplantation is a reconstructive option for patients who have experienced amputation because of trauma.
    MeSH term(s) Acute Disease ; Amputation ; Biomechanical Phenomena ; Biopsy ; Burns, Electric/diagnosis ; Burns, Electric/physiopathology ; Burns, Electric/surgery ; Disability Evaluation ; Forearm/innervation ; Forearm/surgery ; Forearm Injuries/diagnosis ; Forearm Injuries/physiopathology ; Forearm Injuries/surgery ; Graft Rejection/drug therapy ; Graft Rejection/immunology ; Humans ; Immunosuppressive Agents/administration & dosage ; Male ; Mexico ; Middle Aged ; Monitoring, Immunologic ; Organ Transplantation/methods ; Organ Transplantation/rehabilitation ; Patient Satisfaction ; Recovery of Function ; Time Factors ; Treatment Outcome
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000000827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 509: Show issues

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