LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1598

Search options

  1. Article ; Online: Microbiologial diagnosis of prosthetic joint infection: Is there a need for standardization?

    Esteban, Jaime

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2022  Volume 40, Issue 6, Page(s) 287–288

    MeSH term(s) Arthritis, Infectious/diagnosis ; Humans ; Prostheses and Implants ; Prosthesis-Related Infections/diagnosis ; Reference Standards
    Language English
    Publishing date 2022-06-06
    Publishing country Spain
    Document type Editorial ; Comment
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2022.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Biofilm prevention concentration of clarithromycin against clinically relevant species of nontuberculous mycobacteria.

    Senhaji-Kacha, A / Akir, A / Broncano-Lavado, A / Esteban, J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2024  Volume 37, Issue 3, Page(s) 266–269

    Abstract: Objective: Mycobacterium avium complex (MAC) and Mycobacterium abscessus are a group of nontuberculous mycobacteria (NTM) that have been described as human pathogens. Their ability to develop biofilms in tissues and medical devices is one of the most ... ...

    Abstract Objective: Mycobacterium avium complex (MAC) and Mycobacterium abscessus are a group of nontuberculous mycobacteria (NTM) that have been described as human pathogens. Their ability to develop biofilms in tissues and medical devices is one of the most important pathogenicity factors, with important implications in diagnosis and treatment. Macrolides are usually considered one of the bases of this treatment.
    Methods: Here we have studied the biofilm prevention concentration (BPC) of 16 strains (n=16) with clarithromycin to avoid the biofilm development by these NTM.
    Results: In this study, all M. abscessus strains have similar BPC, while MAC strains showed different values. For MAC the concentrations ranged between 1-16 mg/L, while for M. abscessus the concentration was 32 mg/L for all strains except one that was 64 mg/L.
    Conclusions: These results open the possibility of using macrolides for the prevention of biofilm development in patients with a risk of developing NTM disease.
    MeSH term(s) Clarithromycin/pharmacology ; Biofilms/drug effects ; Anti-Bacterial Agents/pharmacology ; Nontuberculous Mycobacteria/drug effects ; Humans ; Microbial Sensitivity Tests ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium Infections, Nontuberculous/drug therapy ; Mycobacterium Infections, Nontuberculous/prevention & control ; Mycobacterium avium Complex/drug effects ; Mycobacterium abscessus/drug effects
    Chemical Substances Clarithromycin (H1250JIK0A) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-04-11
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/014.2024
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Current treatment options for

    Medel-Plaza, Marina / Esteban, Jaime

    Expert opinion on pharmacotherapy

    2023  Volume 24, Issue 10, Page(s) 1113–1123

    Abstract: Introduction: Mycobacterium marinum: Areas covered: We have searched the literature for treatment schemes and drugs used for treatment of M. marinum disease, as well as other therapeutic options.: Expert opinion: Medical treatment is the most ... ...

    Abstract Introduction: Mycobacterium marinum
    Areas covered: We have searched the literature for treatment schemes and drugs used for treatment of M. marinum disease, as well as other therapeutic options.
    Expert opinion: Medical treatment is the most recommended approach option, as
    MeSH term(s) Animals ; Humans ; Mycobacterium marinum ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Macrolides/therapeutic use ; Skin Diseases, Bacterial/diagnosis ; Skin Diseases, Bacterial/drug therapy
    Chemical Substances Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; Anti-Bacterial Agents ; Macrolides
    Language English
    Publishing date 2023-05-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2023.2211258
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5130: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma.

    Rozen, Esteban J / Wigglesworth, Kim / Shohet, Jason M

    Biomedicines

    2024  Volume 12, Issue 1

    Abstract: High-risk neuroblastoma is a very aggressive pediatric cancer, accounting for ~15% of childhood cancer mortality. Therefore, novel therapeutic strategies for the treatment of neuroblastoma are urgently sought. Here, we focused on the potential ... ...

    Abstract High-risk neuroblastoma is a very aggressive pediatric cancer, accounting for ~15% of childhood cancer mortality. Therefore, novel therapeutic strategies for the treatment of neuroblastoma are urgently sought. Here, we focused on the potential implications of the Dual-specificity tYrosine-Regulated Kinase (DYRK) family and downstream signaling pathways. We used bioinformatic analysis of public datasets from neuroblastoma cohorts and cell lines to search correlations between patient survival and expression of
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12010197
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Multi-frequency Electrical Impedance Pneumography System as Point-Of-Care Device.

    Pino, Esteban J / Alvarado, Fabian

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2022  Volume 2022, Page(s) 1414–1417

    Abstract: In this work we present the development of a multi-frequency electrical impedance pneumography (EIP) system based on a portable acquisition device and a mobile platform. This design is intended as an upgrade to our previous device for clinical use in the ...

    Abstract In this work we present the development of a multi-frequency electrical impedance pneumography (EIP) system based on a portable acquisition device and a mobile platform. This design is intended as an upgrade to our previous device for clinical use in the screening of patients with pulmonary diseases. The acquisition device uses the bioimpedance analog front end MAX30001, a mux/demux stage, Bluetooth 4.0 communication and an ESP32 microcontroller unit. It generates an excitation current of 8 μA
    MeSH term(s) Diagnostic Imaging ; Electric Impedance ; Humans ; Point-of-Care Systems
    Language English
    Publishing date 2022-09-09
    Publishing country United States
    Document type Journal Article
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC48229.2022.9870823
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Beyond Milan.

    Dave, Sonya / Esteban, James

    Clinical liver disease

    2022  Volume 21, Issue 3, Page(s) 84–88

    Abstract: 1_erimb8idKaltura. ...

    Abstract 1_erimb8idKaltura.
    Language English
    Publishing date 2022-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1002/cld.1258
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Ultratrace PFAS Detection Using Amplifying Fluorescent Polymers.

    Concellón, Alberto / Castro-Esteban, Jesús / Swager, Timothy M

    Journal of the American Chemical Society

    2023  Volume 145, Issue 20, Page(s) 11420–11430

    Abstract: Per- and poly(fluoroalkyl) substances (PFAS) are environmentally persistent pollutants that are of growing concern due to their detrimental effects at ultratrace concentrations (ng· ... ...

    Abstract Per- and poly(fluoroalkyl) substances (PFAS) are environmentally persistent pollutants that are of growing concern due to their detrimental effects at ultratrace concentrations (ng·L
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c03125
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
    Z 7.3: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Mycobacterium

    Muñoz-Egea, Maria-Carmen / Akir, Arij / Esteban, Jaime

    Biofilm

    2023  Volume 5, Page(s) 100107

    Abstract: ... The ... ...

    Abstract The genus
    Language English
    Publishing date 2023-02-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-2075
    ISSN (online) 2590-2075
    DOI 10.1016/j.bioflm.2023.100107
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: RUN(X) out of blood: emerging RUNX1 functions beyond hematopoiesis and links to Down syndrome.

    Rozen, Esteban J / Ozeroff, Christopher D / Allen, Mary Ann

    Human genomics

    2023  Volume 17, Issue 1, Page(s) 83

    Abstract: Background: RUNX1 is a transcription factor and a master regulator for the specification of the hematopoietic lineage during embryogenesis and postnatal megakaryopoiesis. Mutations and rearrangements on RUNX1 are key drivers of hematological ... ...

    Abstract Background: RUNX1 is a transcription factor and a master regulator for the specification of the hematopoietic lineage during embryogenesis and postnatal megakaryopoiesis. Mutations and rearrangements on RUNX1 are key drivers of hematological malignancies. In humans, this gene is localized to the 'Down syndrome critical region' of chromosome 21, triplication of which is necessary and sufficient for most phenotypes that characterize Trisomy 21.
    Main body: Individuals with Down syndrome show a higher predisposition to leukemias. Hence, RUNX1 overexpression was initially proposed as a critical player on Down syndrome-associated leukemogenesis. Less is known about the functions of RUNX1 in other tissues and organs, although growing reports show important implications in development or homeostasis of neural tissues, muscle, heart, bone, ovary, or the endothelium, among others. Even less is understood about the consequences on these tissues of RUNX1 gene dosage alterations in the context of Down syndrome. In this review, we summarize the current knowledge on RUNX1 activities outside blood/leukemia, while suggesting for the first time their potential relation to specific Trisomy 21 co-occurring conditions.
    Conclusion: Our concise review on the emerging RUNX1 roles in different tissues outside the hematopoietic context provides a number of well-funded hypotheses that will open new research avenues toward a better understanding of RUNX1-mediated transcription in health and disease, contributing to novel potential diagnostic and therapeutic strategies for Down syndrome-associated conditions.
    MeSH term(s) Female ; Humans ; Down Syndrome ; Core Binding Factor Alpha 2 Subunit ; Hematopoiesis ; Chromosomes, Human, Pair 21 ; Carcinogenesis
    Chemical Substances Core Binding Factor Alpha 2 Subunit ; RUNX1 protein, human
    Language English
    Publishing date 2023-09-05
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2147618-4
    ISSN 1479-7364 ; 1479-7364
    ISSN (online) 1479-7364
    ISSN 1479-7364
    DOI 10.1186/s40246-023-00531-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: An update about molecular biology techniques to detect orthopaedic implant-related infections.

    Esteban, Jaime / Gómez-Barrena, Enrique

    EFORT open reviews

    2021  Volume 6, Issue 2, Page(s) 93–100

    Abstract: Despite different criteria to diagnose a prosthetic joint infection (PJI), aetiological diagnosis of the causing microorganism remains essential to guide treatment.Molecular-biology-based PJI diagnosis is progressing (faster, higher specificity) in ... ...

    Abstract Despite different criteria to diagnose a prosthetic joint infection (PJI), aetiological diagnosis of the causing microorganism remains essential to guide treatment.Molecular-biology-based PJI diagnosis is progressing (faster, higher specificity) in different techniques, from the experimental laboratory into clinical use.Multiplex polymerase chain reaction techniques (custom-made or commercial) provide satisfactory results in clinical series of cases, with specificity close to 100% and sensitivity over 70-80%.Next-generation metagenomics may increase sensitivity while maintaining high specificity.Molecular biology techniques may represent, in the next five years, a significant transformation of the currently available microbiological diagnosis in PJI. Cite this article:
    Language English
    Publishing date 2021-02-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2844421-8
    ISSN 2058-5241 ; 2058-5241 ; 2396-7544
    ISSN (online) 2058-5241
    ISSN 2058-5241 ; 2396-7544
    DOI 10.1302/2058-5241.6.200118
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top