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  1. Article: The effects of probiotics, prebiotics, and synbiotics on polycystic ovarian syndrome: an overview of systematic reviews.

    Angoorani, Pooneh / Ejtahed, Hanieh-Sadat / Ettehad Marvasti, Fateme / Taghavi, MinaSadat / Mohammadpour Ahranjani, Behzad / Hasani-Ranjbar, Shirin / Larijani, Bagher

    Frontiers in medicine

    2023  Volume 10, Page(s) 1141355

    Abstract: Introduction: Accumulating evidence has highlighted the critical role of the gut microbiota and its potential action as a regulator of metabolic disorders including insulin resistance, obesity, and systemic inflammation in polycystic ovarian syndrome ( ... ...

    Abstract Introduction: Accumulating evidence has highlighted the critical role of the gut microbiota and its potential action as a regulator of metabolic disorders including insulin resistance, obesity, and systemic inflammation in polycystic ovarian syndrome (PCOS). Microbiota-modulating interventions, such as probiotics, prebiotics, and synbiotics, could be effective in PCOS management.
    Methods: We conducted an overview of systematic reviews (SRs) and meta-analyses to summarize reviews regarding the effectiveness of probiotics/prebiotics/synbiotics on the management of PCOS through a systematic literature search in PubMed, Web of Science, and Scopus databases until September 2021.
    Results: Eight SRs and meta-analyses were included in this study. Our overview confirmed that probiotic supplementation had a potentially beneficial effect on some PCOS-related parameters including body mass index (BMI), fasting plasma glucose (FPG), and lipid profiles. Evidence shows that synbiotics in comparison with probiotics were less effective on these parameters. The methodological quality of SRs was assessed using the AMSTAR-2 assessment tool and was determined as high for four SRs, low for two SRs, and critically low for one SR. Due to limited evidence and high heterogeneity of the studies, it remains difficult to identify optimal probiotics strains, prebiotics types, length of duration, and doses.
    Discussion: Future clinical trials with higher quality are recommended to clarify the efficacy of probiotics/prebiotics/synbiotics on the management of PCOS and provide more accurate evidence.
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1141355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The critical role of gut microbiota dysbiosis in skeletal muscle wasting: a systematic review.

    Nikkhah, Amirabbas / Ejtahed, Hanieh-Sadat / Ettehad Marvasti, Fateme / Taghavi, MinaSadat / Pakmehr, Azin / Hajipour, Firouzeh / Larijani, Bagher

    Journal of applied microbiology

    2023  Volume 134, Issue 1

    Abstract: Aims: Skeletal muscle wasting is affected by the gut microbiota dysbiosis through multiple pathways, including inflammatory process, defected immune system, and anabolic resistance. We aimed to systematically review the studies investigating the gut ... ...

    Abstract Aims: Skeletal muscle wasting is affected by the gut microbiota dysbiosis through multiple pathways, including inflammatory process, defected immune system, and anabolic resistance. We aimed to systematically review the studies investigating the gut microbiota composition in sarcopenic and cachexic humans and animals.
    Methods: We carried out a comprehensively systematic search using relevant keywords on PubMed, Web of Science, and Scopus databases until July 2021. Original human observational research and animal studies related to our research topics published in English were selected.
    Results: Seven human studies and five animal studies were included. Three human studies were case-control, whereas the other four were cross-sectional studies that investigated three different conditions, including age-related sarcopenia, as well as liver cirrhosis and cancer cachexia. The principal alteration in age-related sarcopenia and liver cirrhosis-induced sarcopenia was a reduction in short-chain fatty acids (SCFAs) -producing bacteria. Lachnospiraceae family, consisting of Lachnospira, Fusicatenibacter, Roseburia, and Lachnoclostridium, significantly decreased in age-related sarcopenia, while in liver cirrhosis-induced sarcopenia, the alpha diversity of gut microbiota decreased compared with the control group. Moreover, Enterobacteriaceae, which has a pro-inflammatory effect increased in muscle-wasted animals.
    Conclusion: This systematic review presents associations between the gut microbiota alterations and skeletal muscle wasting as a consequence of various pathologies, including aging sarcopenia, renal failure, and cancer cachexia in both human and animal studies.
    MeSH term(s) Animals ; Humans ; Gastrointestinal Microbiome/physiology ; Sarcopenia ; Muscle, Skeletal/physiology ; Cachexia ; Dysbiosis ; Liver Cirrhosis ; Neoplasms
    Language English
    Publishing date 2023-01-07
    Publishing country England
    Document type Systematic Review ; Journal Article
    ZDB-ID 1358023-1
    ISSN 1365-2672 ; 1364-5072
    ISSN (online) 1365-2672
    ISSN 1364-5072
    DOI 10.1093/jambio/lxac014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Effect of garlic extract on weight loss and gut microbiota composition in obese women: A double-blind randomized controlled trial.

    Ettehad-Marvasti, Fateme / Ejtahed, Hanieh-Sadat / Siadat, Seyed-Davar / Soroush, Ahmad-Reza / Hoseini-Tavassol, Zahra / Hasani-Ranjbar, Shirin / Larijani, Bagher

    Frontiers in nutrition

    2022  Volume 9, Page(s) 1007506

    Abstract: Objective: From a nutritional perspective, garlic extract could be a prebiotic product, which is useful for obese subjects, and one of its health-promoting underlying mechanisms is modulating gut microbiota composition. In this randomized double-blind ... ...

    Abstract Objective: From a nutritional perspective, garlic extract could be a prebiotic product, which is useful for obese subjects, and one of its health-promoting underlying mechanisms is modulating gut microbiota composition. In this randomized double-blind clinical trial, the goal was to determine the effect of
    Materials and methods: Forty-three obese women were randomly divided into garlic extract (400 mg
    Results: In total, 16 subjects in each group completed the 2-month trial. Allium and placebo groups' participants had mean ages of 37.8 ± 7.4 and 34.2 ± 6.8 years, respectively (
    Conclusion: In the both groups, a decrease in BMI and other anthropometric indices has been observed. Despite weight loss after following a low-calorie diet and taking
    Trial registration: This trial was registered in the Iranian Registry of Clinical Trials (IRCT) (code: IRCT090420001825N2).
    Language English
    Publishing date 2022-10-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.1007506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Role of Gut Microbiota-Brain Axis in Pathophysiology of ADHD: A Systematic Review.

    Shirvani-Rad, Salman / Ejtahed, Hanieh-Sadat / Ettehad Marvasti, Fateme / Taghavi, MinaSadat / Sharifi, Farshad / Arzaghi, Seyed Masoud / Larijani, Bagher

    Journal of attention disorders

    2022  Volume 26, Issue 13, Page(s) 1698–1710

    Abstract: Objective: The main goal of this systematic review is to summarize evidences regarding alterations of microbial composition in ADHD cases and uncover underlying mechanisms.: Methods: A comprehensive search was conducted on PubMed, Web of Science, and ...

    Abstract Objective: The main goal of this systematic review is to summarize evidences regarding alterations of microbial composition in ADHD cases and uncover underlying mechanisms.
    Methods: A comprehensive search was conducted on PubMed, Web of Science, and Scopus databases up to March 2021. All the observational studies including case-control, cross-sectional, and cohorts investigating the correlations between the gut microbiota and ADHD in both adults and children were included.
    Results: We found eight eligible studies. Enterococcus, Bifidobacterium, and Odoribacter were increased which may lead to impaired dopamine related functions in CNS. Moreover, decrease of Faecalibacterium frequency in ADHD could result in higher permeability and crossing of inflammatory cytokines. Regarding the short chain fatty acids-producing bacteria, Ruminococcaceae family decreased and Bacteroides uniformis and Bacteroides ovatus species increased.
    Conclusion: Gut microbiota correlation with ADHD and its underlying mechanisms could open new windows for developing novel therapies of ADHD by manipulating microbiota.
    MeSH term(s) Adult ; Attention Deficit Disorder with Hyperactivity ; Brain ; Child ; Cross-Sectional Studies ; Cytokines ; Dopamine ; Fatty Acids, Volatile ; Gastrointestinal Microbiome/physiology ; Humans ; Microbiota
    Chemical Substances Cytokines ; Fatty Acids, Volatile ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 2004350-8
    ISSN 1557-1246 ; 1087-0547
    ISSN (online) 1557-1246
    ISSN 1087-0547
    DOI 10.1177/10870547211073474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5196: Show issues Location:
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  5. Article: The effect of saturated and unsaturated fatty acids on the production of outer membrane vesicles from

    Mirjafari Tafti, Zahra Sadat / Moshiri, Arfa / Ettehad Marvasti, Fateme / Tarashi, Samira / Sadati Khalili, Seyedeh Fatemeh / Motahhary, Atiyyeh / Fateh, Abolfazl / Vaziri, Farzam / Ahmadi Badi, Sara / Siadat, Seyed Davar

    Gastroenterology and hepatology from bed to bench

    2019  Volume 12, Issue 2, Page(s) 155–162

    Abstract: Aim: The aim of present study is to investigate the effect of fatty acids on the outer membrane vesicles (OMVs) produced by : Background: Bacteroides: Methods: B. fragilis: Results: The growths of both : Conclusion: In conclusion we reported ...

    Abstract Aim: The aim of present study is to investigate the effect of fatty acids on the outer membrane vesicles (OMVs) produced by
    Background: Bacteroides
    Methods: B. fragilis
    Results: The growths of both
    Conclusion: In conclusion we reported that palmitic acid had a stimulatory effect on the growth of
    Language English
    Publishing date 2019-05-15
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
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  6. Article ; Online: The First Report of Differences in Gut Microbiota Composition between Obese and Normal Weight Iranian Subjects

    Ettehad Marvasti, Fateme / Moshiri, Arfa / Taghavi, Mina Sadat / Riazi, Soheil / Taati, Majid / Sadati, Seyedeh Fatemeh / Ghaheri, Azadeh / Masoomi, Morteza / Vaziri, Farzam / Fateh, Abolfazl / Rohani, Pejman / Tarashi, Samira / Masotti, Andrea / Ahmadi Badi, Sara / Siadat, Seyed Davar

    Iranian biomedical journal

    2019  Volume 24, Issue 3, Page(s) 148–154

    Abstract: Background: OObesity is a complex disorder influenced by various genetic and environmental factors. It has been shown that gut microbiota, which colonizes gastrointestinal tract, has a substantial role as an environmental factor in the pathophysiology ... ...

    Abstract Background: OObesity is a complex disorder influenced by various genetic and environmental factors. It has been shown that gut microbiota, which colonizes gastrointestinal tract, has a substantial role as an environmental factor in the pathophysiology of obesity. Since the composition of gut microbiota alters with regard to different criteria, such as ethnicity, geographical location, diet, lifestyle, age, and gender, we aimed to determine firmicutes/bacteroidetes (F/B) ratio and the abundance of important gut microbiota members, Akkermansia muciniphila, Faecalibacterium prausnitzii, Roseburia, Bifidobacterium, and Prevotella in Iranian obese and normal weight individuals, for the first time.
    Methods: In this study, 50 normal and 50 obese subjects were recruited and classified based on their BMI into normal weight and obese groups. Stool samples were collected. Following DNA extraction from the samples, quantitative PCR was conducted based on 16s rDNA universal primers. Finally, the correlation between the bacterial abundance and obesity was analyzed by statistical analyses.
    Results: We observed a significant increase of F/B ratio in the obese group, compared to the normal weight group (p = 0.002). Although A. muciniphila (p = 0.039) and Bifidobacterium (p = 0.049) abundance significantly decreased, the abundance of F. prausnitzii (p = 0.046) significantly elevated with BMI increase in the studied groups.
    Conclusion: Owing to the importance of the gut microbiota composition in obesity development, determination and targeted restoration of gut microbiota pattern could be valuable in the control and treatment of obesity in certain populations.
    MeSH term(s) Adult ; Bacteria/metabolism ; Body Mass Index ; Body Weight ; Female ; Gastrointestinal Microbiome ; Humans ; Iran ; Male ; Middle Aged ; Obesity/microbiology ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Young Adult
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2019-12-14
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2489282-8
    ISSN 2008-823X ; 1028-852X
    ISSN (online) 2008-823X
    ISSN 1028-852X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6776: Show issues Location:
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