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Article ; Online: Acceleration of tissue phase mapping by k-t BLAST

Nienhaus G Ulrich / Etyngier Patrick / Manzke Robert / Bornstedt Axel / Lutz Anja / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 13, Iss 1, p

a detailed analysis of the influence of k-t-BLAST for the quantification of myocardial motion at 3T

2011 Volume 5

Abstract: Abstract Background The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high ... ...

Abstract	Abstract Background The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial and temporal resolution is limited by long data acquisition times. Therefore, a significant increase in imaging speed without deterioration of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment of cardiac motion. Results It is demonstrated that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration of the quantitative motion data. Further increasing the k-t acceleration causes substantial alteration of the peak velocities and the motion pattern, but the temporal behavior of the contraction is well maintained up to an acceleration factor of six. Conclusions The application of k-t BLAST for the acceleration of TPM appears feasible. A reduction of the acquisition time of almost 45% could be achieved without substantial loss of quantitative motion information.
Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Active-contour-based image segmentation using machine learning techniques.

Etyngier, Patrick / Ségonne, Florent / Keriven, Renaud

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

2007 Volume 10, Issue Pt 1, Page(s) 891–899

Abstract: We introduce a non-linear shape prior for the deformable model framework that we learn from a set of shape samples using recent manifold learning techniques. We model a category of shapes as a finite dimensional manifold which we approximate using ... ...

Abstract	We introduce a non-linear shape prior for the deformable model framework that we learn from a set of shape samples using recent manifold learning techniques. We model a category of shapes as a finite dimensional manifold which we approximate using Diffusion maps. Our method computes a Delaunay triangulation of the reduced space, considered as Euclidean, and uses the resulting space partition to identify the closest neighbors of any given shape based on its Nyström extension. We derive a non-linear shape prior term designed to attract a shape towards the shape prior manifold at given constant embedding. Results on shapes of ventricle nuclei demonstrate the potential of our method for segmentation tasks.
MeSH term(s)	Adolescent ; Adult ; Algorithms ; Artificial Intelligence ; Cerebral Ventricles/pathology ; Dementia/diagnosis ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods ; Imaging, Three-Dimensional/methods ; Information Storage and Retrieval/methods ; Magnetic Resonance Imaging/methods ; Middle Aged ; Pattern Recognition, Automated/methods ; Reproducibility of Results ; Sensitivity and Specificity
Language	English
Publishing date	2007-11-30
Publishing country	Germany
Document type	Journal Article
DOI	10.1007/978-3-540-75757-3_108
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Article ; Online: SAR reduced black-blood cine TPM for increased temporal resolution at 3T.

Lutz, Anja / Bornstedt, Axel / Manzke, Robert / Nienhaus, G Ulrich / Etyngier, Patrick / Rasche, Volker

Magma (New York, N.Y.)

2011 Volume 24, Issue 3, Page(s) 127–135

Abstract: Object: The objective was to improve the temporal resolution in black-blood CINE tissue phase mapping sequences at high field MR systems. The temporal resolution is limited due to SAR constraints causing idle times into the sequence. The aim was to ... ...

Abstract	Object: The objective was to improve the temporal resolution in black-blood CINE tissue phase mapping sequences at high field MR systems. The temporal resolution is limited due to SAR constraints causing idle times into the sequence. The aim was to avoid these idle times and therefore providing an increased number of heart phases. Materials and methods: Thirteen volunteers were enrolled in this study. Each volunteer underwent different myocardial short-axis scans comprising scans with application of both presaturation pulses, with alternating application of presaturation pulses and with an attenuation of the excitation angle. The last two approaches enable a SAR reduction or increased temporal resolution. The contrast to noise ratio (CNR) between myocardium and blood and the influence on the measured tissue motion were investigated. Results: High CNR between myocardium and blood could be obtained with the application of alternating presaturation-pulses. Reduction of the flip angle of the presaturation-pulses provided reduced CNR relative to both the original and the alternated presaturation-pulses approach. More details of the myocardial motion were observed with increased temporal resolution. Conclusion: It is feasible to increase the temporal resolution at high field strength by reducing the SAR with either alternating presaturation-pulses or decreased flip angle of these pulses.
MeSH term(s)	Absorption ; Adult ; Female ; Heart/anatomy & histology ; Humans ; Image Enhancement/instrumentation ; Image Processing, Computer-Assisted ; Linear Models ; Magnetic Resonance Imaging, Cine/methods ; Male ; Time Factors
Language	English
Publishing date	2011-01-19
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1160826-2
ISSN	1352-8661 ; 0968-5243
ISSN (online)	1352-8661
ISSN	0968-5243
DOI	10.1007/s10334-010-0242-7
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Article ; Online: Acceleration of tissue phase mapping by k-t BLAST: a detailed analysis of the influence of k-t-BLAST for the quantification of myocardial motion at 3T.

Lutz, Anja / Bornstedt, Axel / Manzke, Robert / Etyngier, Patrick / Nienhaus, G Ulrich / Rasche, Volker

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

2011 Volume 13, Page(s) 5

Abstract: Background: The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial ... ...

Abstract	Background: The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial and temporal resolution is limited by long data acquisition times. Therefore, a significant increase in imaging speed without deterioration of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment of cardiac motion. Results: It is demonstrated that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration of the quantitative motion data. Further increasing the k-t acceleration causes substantial alteration of the peak velocities and the motion pattern, but the temporal behavior of the contraction is well maintained up to an acceleration factor of six. Conclusions: The application of k-t BLAST for the acceleration of TPM appears feasible. A reduction of the acquisition time of almost 45% could be achieved without substantial loss of quantitative motion information.
MeSH term(s)	Adolescent ; Adult ; Female ; Germany ; Heart/anatomy & histology ; Heart/physiology ; Humans ; Image Interpretation, Computer-Assisted ; Magnetic Resonance Imaging, Cine ; Male ; Myocardial Contraction ; Time Factors ; Young Adult
Language	English
Publishing date	2011-01-11
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1458034-2
ISSN	1532-429X ; 1097-6647
ISSN (online)	1532-429X
ISSN	1097-6647
DOI	10.1186/1532-429X-13-5
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Article ; Online: Volumetric motion quantification by 3D tissue phase mapped CMR

Lutz Anja / Paul Jan / Bornstedt Axel / Nienhaus G / Etyngier Patrick / Bernhardt Peter / Rottbauer Wolfgang / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss 1, p

2012 Volume 74

Abstract: Abstract Background The objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR. Recent work on myocardial motion quantification by TPM has been focussed on multi-slice 2D acquisitions thus excluding ... ...

Abstract	Abstract Background The objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR. Recent work on myocardial motion quantification by TPM has been focussed on multi-slice 2D acquisitions thus excluding motion information from large regions of the left ventricle. Volumetric motion assessment appears an important next step towards the understanding of the volumetric myocardial motion and hence may further improve diagnosis and treatments in patients with myocardial motion abnormalities. Methods Volumetric motion quantification of the complete left ventricle was performed in 12 healthy volunteers and two patients applying a black-blood 3D TPM sequence. The resulting motion field was analysed regarding motion pattern differences between apical and basal locations as well as for asynchronous motion pattern between different myocardial segments in one or more slices. Motion quantification included velocity, torsion, rotation angle and strain derived parameters. Results All investigated motion quantification parameters could be calculated from the 3D-TPM data. Parameters quantifying hypokinetic or asynchronous motion demonstrated differences between motion impaired and healthy myocardium. Conclusions 3D-TPM enables the gapless volumetric quantification of motion abnormalities of the left ventricle, which can be applied in future application as additional information to provide a more detailed analysis of the left ventricular function.
Keywords	Velocity encoding ; 3D-TPM ; Motion quantification parameters ; Myocardial motion ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-10-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Volumetric motion quantification by 3D velocity encoded MRI

Lutz Anja / Paul Jan / Bornstedt Axel / Nienhaus Gerd / Etyngier Patrick / Bernhardt Peter / Rottbauer Wolfgang / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss Suppl 1, p P

2012 Volume 247

Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-02-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Quantitative assessment of myocardial motion from displacement measurements derived from velocity encoded MRI

Lutz Anja / Paul Jan / Etyngier Patrick / Bornstedt Axel / Nienhaus Gerd / Bernhardt Peter / Rottbauer Wolfgang / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss Suppl 1, p W

2012 Volume 20

Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-02-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Quantitative assessment of myocardial motion from velocity encoded MRI

Lutz Anja / Paul Jan / Etyngier Patrick / Bornstedt Axel / Bernhardt Peter / Nienhaus Gerd / Rottbauer Wolfgang / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss Suppl 1, p W

2012 Volume 39

Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-02-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Acceleration of tissue phase mapping with sensitivity encoding at 3T

Nienhaus G Ulrich / Etyngier Patrick / Manzke Robert / Bornstedt Axel / Lutz Anja / Rottbauer Wolfgang / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 13, Iss 1, p

2011 Volume 59

Abstract: Abstract Background The objective of this study was to investigate the impact of sensitivity encoding on the quantitative assessment of cardiac motion in black blood cine tissue phase mapping (TPM) sequences. Up to now whole volume coverage of the heart ... ...

Abstract	Abstract Background The objective of this study was to investigate the impact of sensitivity encoding on the quantitative assessment of cardiac motion in black blood cine tissue phase mapping (TPM) sequences. Up to now whole volume coverage of the heart is still limited by the long acquisition times. Therefore, a significant increase in imaging speed without deterioration of quantitative motion information is indispensable. Methods 20 volunteers were enrolled in this study. Each volunteer underwent myocardial short-axis TPM scans with different SENSE acceleration factors. The influence of SENSE acceleration on the measured motion curves was investigated. Results It is demonstrated that all TPM sequences with SENSE acceleration have only minimum influence on the motion curves. Even with a SENSE factor of four, the decrease in the amplitude of the motion curve was less than 3%. No significant difference was observed for the global correlation coefficient and deviation between the motion curves obtained by the reproducibility and the SENSE accelerated measurements. Conclusions It is feasible to accelerate myocardial TPM measurements with SENSE factors up to 4 without losing substantial information of the motion pattern.
Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2011-10-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Combination of tagging and tissue phase mapping to accelerate myocardial motion measurements in three directions.

Lutz, Anja / Paul, Jan / Bornstedt, Axel / Nienhaus, Gerd Ulrich / Etyngier, Patrick / Bernhardt, Peter / Rottbauer, Wolfgang / Rasche, Volker

Magma (New York, N.Y.)

2012 Volume 26, Issue 2, Page(s) 239–247

Abstract: Object: Until now, a three-directional velocity field has mostly been obtained by velocity encoding in three directions, which is very time-consuming and hence not usually used in clinical routine. We show the feasibility of combining in-plane tagging ... ...

Abstract	Object: Until now, a three-directional velocity field has mostly been obtained by velocity encoding in three directions, which is very time-consuming and hence not usually used in clinical routine. We show the feasibility of combining in-plane tagging with through-plane tissue phase mapping (TPM) to encode a three-directional velocity field at 3 T with reduced overall acquisition time. Materials and methods: Assessment of a three-directional velocity field was performed for 10 healthy volunteers. The motion patterns obtained by use of five different sequences including three-directional TPM, TPM in the through-plane direction, TPM in the through-plane direction with horizontal or vertical tagging lines, and TPM in the through-plane direction combined with a tagging grid were evaluated and compared. Results: A three-dimensional velocity field can be obtained in approximately half the acquisition time by combining through-plane TPM with in-plane tagging. Although the velocity information is derived by different means, differences between the information obtained by three-directional TPM encoding and the suggested technique are only minor. Conclusion: The combination of tagging and TPM enables assessment of the three-directional velocity field in nearly half the time taken when the conventional three-directional TPM sequence is used.
MeSH term(s)	Adult ; Biomechanical Phenomena ; Female ; Heart/physiology ; Humans ; Imaging, Three-Dimensional ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/statistics & numerical data ; Male ; Motion ; Myocardial Contraction/physiology ; Young Adult
Language	English
Publishing date	2012-08-05
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1160826-2
ISSN	1352-8661 ; 0968-5243
ISSN (online)	1352-8661
ISSN	0968-5243
DOI	10.1007/s10334-012-0333-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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