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  1. Article ; Online: Counseling in menopausal women: How to address the benefits and risks of menopause hormone therapy. A FIGO position paper.

    Genazzani, Andrea R / Divakar, Hema / Khadilkar, Suvarna S / Monteleone, Patrizia / Evangelisti, Bernadette / Galal, Ahmed F / Priego, Paola I R / Simoncini, Tommaso / Giannini, Andrea / Goba, Gelila / Benedetto, Chiara

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2024  Volume 164, Issue 2, Page(s) 516–530

    Abstract: Menopause marks the end of menstrual cyclicity and, depending on individual vulnerability, has several consequences related to gonadal steroid deprivation, especially if it is premature. Menopause may be more burdensome for some women than for others. ... ...

    Abstract Menopause marks the end of menstrual cyclicity and, depending on individual vulnerability, has several consequences related to gonadal steroid deprivation, especially if it is premature. Menopause may be more burdensome for some women than for others. Individual factors, such as personal history, socioeconomic status, ethnicity, and current health conditions, affect symptomatology and, thereby, the menopausal experience. In addition, some menopausal symptoms, such as severe hot flashes, sleep disorders, and depression, are markers of future health risks. Counseling is a fundamental part of health care in the peri- and postmenopause periods. It must include an assessment of the patient's symptoms, needs, desires, and risk profile to address the benefits and risks of menopausal hormone therapy (MHT) on an individual basis and promote a healthy lifestyle. Indeed, healthcare practitioners can and must protect the health and lives of mid-life women by increasing awareness of menopausal symptoms and ensuring healthcare options, especially MHT. The type and duration of MHT should be tailored based on the patient's history, menopausal age, physical characteristics, and current health status so that the benefits always outweigh the risks. This FIGO position paper focuses on the benefits and risks of MHT on health domains, target organs, and systems, and on systemic and vaginal MHT regimens, to provide indications that can be used in the clinical practice for menopausal counseling. Moreover, it offers insights into what FIGO considers the mainstay for the healthcare management of women in peri- and postmenopause, worldwide.
    MeSH term(s) Female ; Humans ; Estrogen Replacement Therapy/adverse effects ; Menopause ; Postmenopause ; Counseling ; Risk Assessment ; Hormone Replacement Therapy
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.15278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Reproductive and Obstetric Outcomes Following a Natural Cycle vs. Artificial Endometrial Preparation for Frozen-Thawed Embryo Transfer: A Retrospective Cohort Study.

    Carosso, Andrea Roberto / Brunod, Nicole / Filippini, Claudia / Revelli, Alberto / Evangelisti, Bernadette / Cosma, Stefano / Borella, Fulvio / Canosa, Stefano / Benedetto, Chiara / Gennarelli, Gianluca

    Journal of clinical medicine

    2023  Volume 12, Issue 12

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-06-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12124032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Luteal Support with very Low Daily Dose of Human Chorionic Gonadotropin after Fresh Embryo Transfer as an Alternative to Cycle Segmentation for High Responders Patients Undergoing Gonadotropin-Releasing Hormone Agonist-Triggered IVF.

    Carosso, Andrea Roberto / Canosa, Stefano / Gennarelli, Gianluca / Sestero, Marta / Evangelisti, Bernadette / Charrier, Lorena / Bergandi, Loredana / Benedetto, Chiara / Revelli, Alberto

    Pharmaceuticals (Basel, Switzerland)

    2021  Volume 14, Issue 3

    Abstract: The segmentation of the in vitro fertilization (IVF) cycle, consisting of the freezing of all embryos and the postponement of embryo transfer (ET), has become popular in recent years, with the main purpose of preventing ovarian hyperstimulation syndrome ( ...

    Abstract The segmentation of the in vitro fertilization (IVF) cycle, consisting of the freezing of all embryos and the postponement of embryo transfer (ET), has become popular in recent years, with the main purpose of preventing ovarian hyperstimulation syndrome (OHSS) in patients with high response to controlled ovarian stimulation (COS). Indeed cycle segmentation (CS), especially when coupled to a GnRH-agonist trigger, was shown to reduce the incidence of OHSS in high-risk patients. However, CS increases the economic costs and the work amount for IVF laboratories. An alternative strategy is to perform a fresh ET in association with intensive luteal phase pharmacological support, able to overcome the negative effects of the GnRH-agonist trigger on the luteal phase and on endometrial receptivity. In order to compare these two strategies, we performed a retrospective, real-life cohort study including 240 non-polycystic ovarian syndrome (PCO) women with expected high responsiveness to COS (AMH >2.5 ng/mL), who received either fresh ET plus 100 IU daily human chorionic gonadotropin (hCG) as luteal support (FRESH group,
    Language English
    Publishing date 2021-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph14030228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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