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  1. AU="Evans, Ronald K"
  2. AU="Pemmaraju, Venkata Ranganandha Rao"
  3. AU="Chu, Kimberly"
  4. AU="Finton, Kathryn A K"
  5. AU="Lou Alcaine, María Luz"
  6. AU="Patterson, G Taylor"
  7. AU="Champey, Patrick R" AU="Champey, Patrick R"
  8. AU="Zyriax, Birgit-Christiane"
  9. AU="Kim, Elaine H"
  10. AU="Zhou, Gui-Xiu"
  11. AU="Baer, Rebecca J"
  12. AU="Fleck, Robert J"

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  1. Artikel: Using measured resting metabolic rate to derive calorie prescriptions in a behavioral weight loss program

    Lanoye, Autumn / Evans, Ronald K. / Leahey, Tricia M. / LaRose, Jessica G.

    Obesity science & practice. 2021 June, v. 7, no. 3

    2021  

    Abstract: OBJECTIVE: Within behavioral weight loss (BWL) programs, using measured resting metabolic rate (RMR) is a more accurate—yet costlier—alternative to the standard method of assigning calorie prescriptions using baseline weight. This investigation aimed to ... ...

    Abstract OBJECTIVE: Within behavioral weight loss (BWL) programs, using measured resting metabolic rate (RMR) is a more accurate—yet costlier—alternative to the standard method of assigning calorie prescriptions using baseline weight. This investigation aimed to assess differences between calorie goals prescribed using each method including demographic predictors and associations with weight loss. METHODS: This is an ancillary study to a trial comparing approaches to motivational enhancement in a 6‐months BWL program designed for emerging adults age 18–25 (N = 308). RMR was measured at baseline and used to derive calorie prescriptions; standard calorie goals were retrospectively assigned for the purpose of these analyses. RESULTS: Standard calorie prescriptions were significantly higher than those derived from RMR. Sex and race were significant predictors of calorie prescription discrepancies: using the standard method, women and Black participants were assigned higher calorie goals than their RMR would indicate. Calorie goal discrepancy did not predict 6‐months weight change. CONCLUSIONS: Differences in calorie prescriptions between approaches were significant; however, it remains to be determined whether measuring RMR is worth the cost, time, and participant burden. It may be the case that this consideration has greater impact for certain subgroups—namely, women and Black participants.
    Schlagwörter metabolism ; obesity ; weight loss
    Sprache Englisch
    Erscheinungsverlauf 2021-06
    Umfang p. 335-338.
    Erscheinungsort John Wiley & Sons, Ltd
    Dokumenttyp Artikel
    Anmerkung JOURNAL ARTICLE
    ZDB-ID 2836381-4
    ISSN 2055-2238
    ISSN 2055-2238
    DOI 10.1002/osp4.489
    Datenquelle NAL Katalog (AGRICOLA)

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  2. Artikel ; Online: Using measured resting metabolic rate to derive calorie prescriptions in a behavioral weight loss program.

    Lanoye, Autumn / Evans, Ronald K / Leahey, Tricia M / LaRose, Jessica G

    Obesity science & practice

    2021  Band 7, Heft 3, Seite(n) 335–338

    Abstract: Objective: Within behavioral weight loss (BWL) programs, using measured resting metabolic rate (RMR) is a more accurate-yet costlier-alternative to the standard method of assigning calorie prescriptions using baseline weight. This investigation aimed to ...

    Abstract Objective: Within behavioral weight loss (BWL) programs, using measured resting metabolic rate (RMR) is a more accurate-yet costlier-alternative to the standard method of assigning calorie prescriptions using baseline weight. This investigation aimed to assess differences between calorie goals prescribed using each method including demographic predictors and associations with weight loss.
    Methods: This is an ancillary study to a trial comparing approaches to motivational enhancement in a 6-months BWL program designed for emerging adults age 18-25 (
    Results: Standard calorie prescriptions were significantly higher than those derived from RMR. Sex and race were significant predictors of calorie prescription discrepancies: using the standard method, women and Black participants were assigned higher calorie goals than their RMR would indicate. Calorie goal discrepancy did not predict 6-months weight change.
    Conclusions: Differences in calorie prescriptions between approaches were significant; however, it remains to be determined whether measuring RMR is worth the cost, time, and participant burden. It may be the case that this consideration has greater impact for certain subgroups-namely, women and Black participants.
    Sprache Englisch
    Erscheinungsdatum 2021-03-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2836381-4
    ISSN 2055-2238 ; 2055-2238
    ISSN (online) 2055-2238
    ISSN 2055-2238
    DOI 10.1002/osp4.489
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  3. Artikel ; Online: The contribution of fat-free mass to resting energy expenditure: implications for weight loss strategies in the treatment of adolescent obesity.

    Browning, Matthew G / Evans, Ronald K

    International journal of adolescent medicine and health

    2015  Band 27, Heft 3, Seite(n) 241–246

    Abstract: Owing to the strong relationship between fat-free mass (FFM) and resting energy expenditure (REE), the preservation of FFM is often emphasized in the treatment of adolescent obesity. Typical treatment regimens including an increased dietary consumption ... ...

    Abstract Owing to the strong relationship between fat-free mass (FFM) and resting energy expenditure (REE), the preservation of FFM is often emphasized in the treatment of adolescent obesity. Typical treatment regimens including an increased dietary consumption of protein and participation in resistance training are common components of adolescent weight management programs, despite limited evidence of a positive influence of FFM on weight loss outcomes in adolescents. Given the larger volume of FFM in obese relative to normal weight adolescents and the common treatment goals of both maximizing weight loss and attenuating the loss of FFM, a better understanding of the influence of FFM on energy balance is needed to determine whether strategies to preserve lean tissue or maximize absolute weight loss should be most emphasized. We review the associations among FFM, REE, and weight loss outcomes, focusing on how these relationships might influence energy balance in obese adolescents.
    Mesh-Begriff(e) Adolescent ; Body Composition/physiology ; Body Constitution ; Diet, Reducing ; Energy Metabolism/physiology ; Exercise ; Female ; Humans ; Male ; Pediatric Obesity/metabolism ; Pediatric Obesity/therapy ; Rest ; United States ; Weight Loss
    Sprache Englisch
    Erscheinungsdatum 2015-08
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Review
    ZDB-ID 639287-8
    ISSN 2191-0278 ; 0334-0139
    ISSN (online) 2191-0278
    ISSN 0334-0139
    DOI 10.1515/ijamh-2014-0036
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  4. Artikel ; Online: An appraisal of whole-room indirect calorimeters and a metabolic cart for measuring resting and active metabolic rates.

    Chen, Shanshan / Scott, Cory / Pearce, Janina V / Farrar, Jared S / Evans, Ronald K / Celi, Francesco S

    Scientific reports

    2020  Band 10, Heft 1, Seite(n) 14343

    Abstract: Whole-room indirect calorimeters (WRICs) have traditionally been used for real-time resting metabolic rate (RMR) measurements, while metabolic rate (MR) during short-interval exercises has commonly been measured by metabolic carts (MCs). This study aims ... ...

    Abstract Whole-room indirect calorimeters (WRICs) have traditionally been used for real-time resting metabolic rate (RMR) measurements, while metabolic rate (MR) during short-interval exercises has commonly been measured by metabolic carts (MCs). This study aims to investigate the feasibility of incorporating short-interval exercises into WRIC study protocols by comparing the performance of WRICs and an MC. We assessed the 40-min RMR of 15 subjects with 2-day repeats and the 10-15 min activity MR (AMR) of 14 subjects at three intensities, using a large WRIC, a small WRIC, and an MC. We evaluated the biases between the instruments and quantified sources of variation using variance component analysis. All three instruments showed good agreement for both RMR (maximum bias = 0.07 kcal/min) and AMR assessment (maximum bias = 0.53 kcal/min). Moreover, the majority of the variability was between-subject and between-intensity variation, whereas the types of instrument contributed only a small amount to total variation in RMR (2%) and AMR (0.2%) data. In Conclusion, the good reproducibility among the instruments indicates that they may be used interchangeably in well-designed studies. Overall, WRICs can serve as an accurate and versatile means of assessing MR, capable of integrating RMR and short-interval AMR assessments into a single protocol.
    Mesh-Begriff(e) Basal Metabolism ; Calorimetry, Indirect/instrumentation ; Energy Metabolism ; Exercise ; Female ; Humans ; Male ; Reproducibility of Results
    Sprache Englisch
    Erscheinungsdatum 2020-08-31
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-71001-1
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  5. Artikel ; Online: The role of parents in behavioral treatment for adolescent obesity: design and rationale for the TEENS+ randomized clinical trial.

    Bean, Melanie K / LaRose, Jessica Gokee / Wickham, Edmond P / Raynor, Hollie A / Caccavale, Laura / Evans, Ronald K / Thornton, Laura M / Farthing, Sarah / Mendoza, Ashley / Mazzeo, Suzanne E

    BMC public health

    2023  Band 23, Heft 1, Seite(n) 1484

    Abstract: Background: There is an urgent need for innovative approaches to adolescent obesity treatment, particularly among individuals from racially and ethnically marginalized backgrounds, who face increased risk of obesity and its associated morbidity and ... ...

    Abstract Background: There is an urgent need for innovative approaches to adolescent obesity treatment, particularly among individuals from racially and ethnically marginalized backgrounds, who face increased risk of obesity and its associated morbidity and mortality. There is a particular dearth of research on the long-term efficacy of adolescent obesity treatments. Further, research and clinical practice guidelines consistently recommend parents' inclusion in their adolescents' obesity treatment, yet the most effective strategy to engage parents in adolescent obesity treatment remains unclear. Towards that end, this investigation will conduct a fully-powered, randomized clinical trial to examine the efficacy of two distinct approaches to involving parents in their adolescents' obesity treatment.
    Methods: Participants will be 210 12-16 year old adolescents (body mass index [BMI]≥85
    Discussion: Results of this investigation have the potential to significantly advance science in this area and ultimately inform clinical practice guidelines related to the role of parents in adolescent obesity treatment.
    Trial registration: Clinicaltrials.gov NCT03851796. Registered: February 22, 2019.
    Mesh-Begriff(e) Child ; Adolescent ; Humans ; Pediatric Obesity/prevention & control ; Body Mass Index ; Parents/education ; Behavior Therapy ; Overweight/therapy
    Sprache Englisch
    Erscheinungsdatum 2023-08-04
    Erscheinungsland England
    Dokumenttyp Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16421-0
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  6. Artikel ; Online: Effect of a Lifestyle Intervention on Cardiometabolic Health Among Emerging Adults: A Randomized Clinical Trial.

    LaRose, Jessica Gokee / Leahey, Tricia M / Lanoye, Autumn / Bean, Melanie K / Fava, Joseph L / Tate, Deborah F / Evans, Ronald K / Wickham, Edmond P / Henderson, Megan M

    JAMA network open

    2022  Band 5, Heft 9, Seite(n) e2231903

    Abstract: Importance: The prevalence of obesity has increased substantially among emerging adults, yet no previous large-scale behavioral weight loss trials have been conducted among this age group.: Objective: To test the effect of 2 theory-based motivational ...

    Abstract Importance: The prevalence of obesity has increased substantially among emerging adults, yet no previous large-scale behavioral weight loss trials have been conducted among this age group.
    Objective: To test the effect of 2 theory-based motivational enhancements on weight loss within a primarily digital lifestyle intervention designed for emerging adults.
    Design, setting, and participants: In this randomized clinical trial conducted at an academic medical research center, 382 participants aged 18 to 25 years with a body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of 25 to 45 were enrolled between February 2, 2016, and February 6, 2019. Data collection was completed February 8, 2020. Analysis was performed on an intention-to-treat basis.
    Interventions: Participants were randomized to 1 of 3 groups: developmentally adapted behavioral weight loss (aBWL), aBWL plus behavioral economics (aBWL + BE), or aBWL plus self-determination theory (aBWL + SDT). All groups received a 6-month intervention with 1 group session, 1 individual session, and a digital platform (digital tools for self-monitoring, weekly lessons, tailored feedback, text messages, and optional social media). The aBWL + BE group received modest financial incentives for self-monitoring and weight loss; the aBWL + SDT group received optional experiential classes. Coaching and message framing varied by group.
    Main outcomes and measures: The primary outcome was mean (SE) weight change (in kilograms) at 6 months. Secondary outcomes included proportion of participants achieving weight loss of 5% or more, percentage weight change, waist circumference, body composition, and blood pressure.
    Results: Among the 382 participants (mean [SD] age, 21.9 [2.2] years), 316 (82.7%) were female, mean (SD) BMI was 33.5 (4.9), 222 (58.1%) were of underrepresented race and/or ethnicity, and 320 (83.8%) were retained at the primary end point. There was a significant time effect for mean (SE) weight loss (-3.22 [0.55] kg in the aBWL group; -3.47 [0.55] kg in the aBWL + BE group; and -3.40 [0.53] kg in the aBWL + SDT group; all P < .001), but no between-group differences were observed (aBWL vs aBWL + BE: difference, -0.25 kg [95% CI, -1.79 to 1.29 kg]; P = .75; aBWL vs aBWL + SDT: difference, -0.18 kg [95% CI, -1.67 to 1.31 kg]; P = .81; and aBWL + SDT vs aBWL + BE: difference, 0.07 kg [95% CI, -1.45 to 1.59 kg]; P = .93). The proportion of participants achieving a weight loss of 5% or more was 40.0% in the aBWL group (50 of 125), 39.8% in the aBWL + BE group (51 of 128), and 44.2% in the aBWL + SDT group (57 of 129), which was not statistically different across groups (aBWL vs aBWL + BE, P = .89; aBWL vs aBWL + SDT, P = .45; aBWL + SDT vs aBWL + BE, P = .54). Parallel findings were observed for all secondary outcomes-clinically and statistically significant improvements with no differences between groups.
    Conclusions and relevance: In this randomized clinical trial, all interventions produced clinically significant benefit, but neither of the motivational enhancements promoted greater reductions in adiposity compared with the developmentally adapted standard group. Continued efforts are needed to optimize lifestyle interventions for this high-risk population and determine which intervention works best for specific individuals based on sociodemographic and/or psychosocial characteristics.
    Trial registration: ClinicalTrials.gov Identifier: NCT02736981.
    Mesh-Begriff(e) Adult ; Body Mass Index ; Cardiovascular Diseases ; Female ; Humans ; Life Style ; Male ; Obesity/epidemiology ; Obesity/therapy ; Weight Loss ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2022-09-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2022.31903
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Influence of extracellular volume fraction on peak exercise oxygen pulse following thoracic radiotherapy.

    Canada, Justin M / Weiss, Elisabeth / Grizzard, John D / Trankle, Cory R / Gharai, Leila Rezai / Dana, Franklin / Buckley, Leo F / Carbone, Salvatore / Kadariya, Dinesh / Ricco, Anthony / Jordan, Jennifer H / Evans, Ronald K / Garten, Ryan S / Van Tassell, Benjamin W / Hundley, W Gregory / Abbate, Antonio

    Cardio-oncology (London, England)

    2022  Band 8, Heft 1, Seite(n) 1

    Abstract: Background: Radiation-induced myocardial fibrosis increases heart failure (HF) risk and is associated with a restrictive cardiomyopathy phenotype. The myocardial extracellular volume fraction (ECVF) using contrast-enhanced cardiac magnetic resonance ( ... ...

    Abstract Background: Radiation-induced myocardial fibrosis increases heart failure (HF) risk and is associated with a restrictive cardiomyopathy phenotype. The myocardial extracellular volume fraction (ECVF) using contrast-enhanced cardiac magnetic resonance (CMR) quantifies the extent of fibrosis which, in severe cases, results in a noncompliant left ventricle (LV) with an inability to augment exercise stroke volume (SV). The peak exercise oxygen pulse (O
    Methods: Patients who underwent thoracic radiotherapy for chest malignancies with significant incidental heart dose (≥5 Gray (Gy), ≥10% heart) without a pre-cancer treatment history of HF underwent cardiopulmonary exercise testing to determine O
    Results: Thirty patients (median [IQR] age 63 [57-67] years, 18 [60%] female, 2.0 [0.6-3.8] years post-radiotherapy) were included. The peak VO
    Conclusions: In patients with prior radiotherapy heart exposure, %-predicted O
    Sprache Englisch
    Erscheinungsdatum 2022-01-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2057-3804
    ISSN (online) 2057-3804
    DOI 10.1186/s40959-021-00127-6
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  8. Artikel ; Online: Excess Blood Flow Response to Acute Resistance Exercise in Individuals Who are Obese or Nonobese.

    Lipford, Grayson F / Evans, Ronald K / Acevedo, Edmund O / Wolfe, Luke G / Franco, R Lee

    Journal of strength and conditioning research

    2017  Band 31, Heft 11, Seite(n) 3120–3127

    Abstract: Lipford, GF, Evans, RK, Acevedo, EO, Wolfe, LG, and Franco, RL. Excess blood flow response to acute resistance exercise in individuals who are obese or nonobese. J Strength Cond Res 31(11): 3120-3127, 2017-Resistance exercise (RE) is a commonly ... ...

    Abstract Lipford, GF, Evans, RK, Acevedo, EO, Wolfe, LG, and Franco, RL. Excess blood flow response to acute resistance exercise in individuals who are obese or nonobese. J Strength Cond Res 31(11): 3120-3127, 2017-Resistance exercise (RE) is a commonly recommended treatment option for obese individuals. However, little is known regarding alterations in vasodilatory responses to RE, which could impair exercise tolerance. No studies to date have compared microvascular vasodilatory capacity, assessed by excess blood flow (EBF), responses in individuals who are obese or nonobese following acute RE. The purpose of the study was to evaluate EBF before and up to 24-hour after a single RE bout in obese (n = 18, 38.1 ± 7.64% body fat) and nonobese (n = 10, 23.6 ± 4.03% body fat) individuals who volunteered to participate. Each subject completed a leg flexion and knee extension one repetition maximum (1RM) test, and subsequently completed 4 sets of 8 repetitions at 85% of 1RM. Excess blood flow, adiponectin, and tumor necrosis factor α (TNF-α) were evaluated at baseline (PRE-RE), immediately after (POST-RE), and 1 (POST-1) and 24 (POST-24) hours after exercise. A repeated-measures analysis of variance revealed a significant interaction for EBF between the 2 groups (p = 0.029). The estimated marginal means plot suggested that obese individuals had a significant increase in POST-RE EBF in comparison with PRE-RE EBF (428.54 ± 261.59 vs. 547.00 ± 311.15 ml/100 ml/min·s; p = 0.046). In addition, EBF significantly decreased at POST-24 in comparison with POST-RE in the obese individuals (547.00 ± 311.15 vs. 389.33 ± 252.32 ml/100 ml/min·s; p = 0.011). Changes in EBF were not related to adiponectin or TNF-α. An acute bout of RE resulted in an opposite EBF response between nonobese and obese individuals immediately after RE. Furthermore, only the obese individuals displayed a significant increase in EBF immediately after RE, which was significantly reduced 24 hours after the RE bout. Microvascular vasodilatory capacity may alter the adaptive exercise response associated with RE, requiring alterations to frequency, intensity, and/or duration that are specific to populations of various body composition profiles.
    Sprache Englisch
    Erscheinungsdatum 2017-11
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1156349-7
    ISSN 1533-4287 ; 1064-8011
    ISSN (online) 1533-4287
    ISSN 1064-8011
    DOI 10.1519/JSC.0000000000001748
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  9. Artikel ; Online: Assessment of Cardiopulmonary Responses to Treadmill Walking Following Gastric Bypass Surgery.

    Browning, Matthew G / Franco, Robert L / Herrick, Jeffrey E / Arrowood, James A / Evans, Ronald K

    Obesity surgery

    2017  Band 27, Heft 1, Seite(n) 96–101

    Abstract: Background: Studies that have evaluated cardiopulmonary responses to exercise within the first few months of bariatric surgery have utilized cycle ergometry. However, walking is the most commonly reported mode of both pre- and post-operative PA. The ... ...

    Abstract Background: Studies that have evaluated cardiopulmonary responses to exercise within the first few months of bariatric surgery have utilized cycle ergometry. However, walking is the most commonly reported mode of both pre- and post-operative PA. The divergent cardiopulmonary responses and metabolic costs of weight-bearing (walking) and non-weight-bearing (cycling) exercises warrant examination of the effects of bariatric surgery on cardiopulmonary responses during walking.
    Methods: Nine women completed a maximal cardiopulmonary exercise test on a treadmill 2 weeks before and 3 months after gastric bypass surgery (GBS). Heart rate (HR), oxygen uptake (VO
    Results: Time to fatigue increased by ~140 s following GBS (p = 0.018). No other parameter improved during maximal exercise from pre- to post-surgery. Body weight- and fat-free mass-corrected VO
    Conclusion: We have demonstrated that weight loss alone was not sufficient to improve select cardiopulmonary fitness measures during treadmill walking in obese females 3 months after GBS. However, we did observe a significant overall improvement in exercise capacity as the GBS group was able to exercise longer, presumably due to significant reductions in body mass and a subsequent reduced metabolic cost of walking.
    Sprache Englisch
    Erscheinungsdatum 2017-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-016-2259-0
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  10. Artikel ; Online: Recruitment and retention of families interested in a parent-based pediatric obesity intervention.

    Mazzeo, Suzanne E / Burnette, C Blair / Stern, Marilyn / Thornton, Laura M / Bulik, Cynthia M / Evans, Ronald K / Gow, Rachel W

    Contemporary clinical trials communications

    2019  Band 16, Seite(n) 100467

    Abstract: Recruitment and retention in pediatric obesity treatment remains challenging, especially for groups at highest risk of this condition, including African Americans. However, most investigations examine attrition during intervention or follow-up. Little is ...

    Abstract Recruitment and retention in pediatric obesity treatment remains challenging, especially for groups at highest risk of this condition, including African Americans. However, most investigations examine attrition during intervention or follow-up. Little is known about those who refuse enrollment, or drop out at baseline. Thus, the trajectory of recruitment, enrollment, and retention, especially at these early stages, is not well understood, limiting knowledge of treatment access. This study examined enrollment in a pediatric weight management intervention. We provide demographic information on nested consort flow groups. We compared non-overlapping interest/enrollment groups to examine differences between those who progressed to the next consort flow group and those who did not; specifically the four groups examined were: (1) eligible at screening, did not attend baseline (
    Sprache Englisch
    Erscheinungsdatum 2019-10-12
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2451-8654
    ISSN (online) 2451-8654
    DOI 10.1016/j.conctc.2019.100467
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