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  1. Article ; Online: Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V

    Kostareva, Olga / Svoeglazova, Arina / Kolyadenko, Ilya / Nikulin, Alexey / Evdokimov, Stanislav / Dzhus, Uliana / Gabdulkhakov, Azat / Tishchenko, Svetlana

    International journal of molecular sciences

    2022  Volume 23, Issue 23

    Abstract: Interleukin-17 (IL-17) is a cytokine produced by the Th17 cells. It is involved in chronic inflammation in patients with autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and psoriasis. The antibodies ... ...

    Abstract Interleukin-17 (IL-17) is a cytokine produced by the Th17 cells. It is involved in chronic inflammation in patients with autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and psoriasis. The antibodies targeting IL-17 and/or IL-17R are therapy tools for these diseases. Netakimab is an IL-17A-specific antibody containing a
    Language English
    Publishing date 2022-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232314904
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  2. Article ; Online: The economic efficiency of investment in the development of reserves of small groups of geographically contiguous gold deposits

    Evdokimov S.I. / Galachieva S.V. / Tebloeva D.V.

    SHS Web of Conferences, Vol 35, p

    2017  Volume 01133

    Abstract: The object of the research is a group of geographically contiguous low volume gold deposits. The subject of the study is an economic justification for a way to involve economic turnover to get a positive commercial result on a specially formed group of ... ...

    Abstract The object of the research is a group of geographically contiguous low volume gold deposits. The subject of the study is an economic justification for a way to involve economic turnover to get a positive commercial result on a specially formed group of gold deposits, in which individual field development is unprofitable. A small production volume, combined with high capital and operating costs are objective reasons for the reduction in investment attractiveness of the deposits which have reserves of gold of <25 tons in the “supply and demand” chain. The economic result will be fundamentally different if the production capacity of the company is increased by combining geographically contiguous low volume deposits in the group where the total reserves of the mountain holding are represented as one deposit. A criteria was developed and it was determined that the economic and technological constraints for the deposit to enter the group would be outpacing growth of the recoverable value of reserves as compared with a decline in their gold content. Deposits of the group are rationally developed on a rotational basis with a seasonal operating mode of small mining enterprises (with an annual underground mining of 5000–50000 tons up to 100,000 tons, with private ownership >50%), equipped with a mobile processing complex with deep processing technology on highly liquid commodity products on site. An economic-mathematical model was devised to determine the rational placement of the processing capacity of the group.A simulation was conducted and an economic evaluation was performed on the effectiveness of investments in individual and group mining projects. The simulation results show that the joint exploitation of the reserves of the group of deposits, the internal rate of return on investments exceed the rate of return of funds to the bank deposit, the return on investment is above the level of inflation. The group project complies with the strategic line of small mining companies in terms of cost recovery terms, ...
    Keywords Social Sciences ; H
    Subject code 330
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Thesis: Secure outsourcing of IT services in a non-trusted environment

    Evdokimov, Sergej

    2008  

    Author's details von Sergei Evdokimov
    Keywords Internetbasierter Dienst ; Datenbank ; Unternehmensarchitektur ; Datensicherheit ; Komplexe Systeme
    Language English
    Size 115 S., graph. Darst, 29 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Berlin, Humboldt-Univ., Diss, 2008 (Nicht für den Austausch)
    Note Sprache der Zusammenfassung: Deutsch ; Zsfassung in dt. Sprache
    Database ECONomics Information System

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  4. Article ; Online: Assessment of Biocompatibility and Local Action of Biomaterial for Production of an Envelope for Implanted Heart Electronic Devices.

    Shadrina, D V / Venediktov, A A / Evdokimov, S V / Vaskovskii, V A / Artyukhina, E A / Revishvili, A Sh / Durmanov, S S / Bazylev, V V

    Bulletin of experimental biology and medicine

    2020  Volume 168, Issue 3, Page(s) 375–377

    Abstract: We studied a biomaterial for a new domestic product, a biological envelope for implantation of cardiac electronic devices. The product is designed to prevent complications after pacemaker implantation and to facilitate the reimplantation procedure. By ... ...

    Abstract We studied a biomaterial for a new domestic product, a biological envelope for implantation of cardiac electronic devices. The product is designed to prevent complications after pacemaker implantation and to facilitate the reimplantation procedure. By chemical and biological processing of raw materials (submucosa of porcine small intestine), an acellular extracellular collagen matrix was obtained. The biocompatibility of the material was tested in vitro using stem cell cultures. The biomaterial for fabrication of the envelope is not cytotoxic, biocompatible, and represents a suitable substrate for attachment, growth, and reproduction of stem cells. The biological effect of the material was studied in vivo on the model of heterotopic implantation in small laboratory animals. The biomaterial did not induce inflammation and tissue reaction and was completely transformed into healthy vascularized tissue without scars in 90 days after implantation.
    MeSH term(s) Animals ; Biocompatible Materials/chemistry ; Collagen/metabolism ; Extracellular Matrix/metabolism ; Inflammation/metabolism ; Male ; Materials Testing ; Myocardium/cytology ; Prostheses and Implants ; Swine ; Tissue Engineering/methods
    Chemical Substances Biocompatible Materials ; Collagen (9007-34-5)
    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390407-6
    ISSN 1573-8221 ; 0007-4888 ; 0365-9615
    ISSN (online) 1573-8221
    ISSN 0007-4888 ; 0365-9615
    DOI 10.1007/s10517-020-04712-0
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  5. Article: [Local EEG characteristics of the children with psychic abnormalities, examined by independent components analysis (ICA)].

    Kozhushko, N Iu / Evdokimov, S A / Matveev, Iu K / Tereshchenko, E P / Kropotov, Iu D

    Fiziologiia cheloveka

    2014  Volume 40, Issue 5, Page(s) 30–37

    Abstract: The method of independent components within the range of 3-13 Hz was used for the analysis of EEG of the children with psychic abnormalities of perinatal origin. The research was undertaken while children were keeping awake with open eyes. In cases of ... ...

    Abstract The method of independent components within the range of 3-13 Hz was used for the analysis of EEG of the children with psychic abnormalities of perinatal origin. The research was undertaken while children were keeping awake with open eyes. In cases of harder developmental delay it was revealed a significant rise of θ-range power spectrum in frontal-temporal cortex areas of left hemisphere and temporal areas of right hemisphere. This fact make it possible to regard these areas as hypothetic sources of slow activity and a damage/immaturity marker of frontal-thalamic area and the temporal areas, responsible for auditory analysis and verbal synthesis, audio & visual data integration.
    MeSH term(s) Brain Mapping ; Child ; Developmental Disabilities/physiopathology ; Electroencephalography ; Female ; Frontal Lobe/physiopathology ; Humans ; Male ; Temporal Lobe/physiopathology ; Visual Perception/physiology
    Language Russian
    Publishing date 2014-09
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 194077-6
    ISSN 0131-1646
    ISSN 0131-1646
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  6. Article: Different resting state EEG features in children from Switzerland and Saudi Arabia

    Alahmadi, Nsreen / Evdokimov, Sergey A. / Kropotov, Yury (Juri) / Müller, Andreas M. / Jäncke, Lutz

    Frontiers in Human Neuroscience

    2016  

    Abstract: Background: Cultural neuroscience is an emerging research field concerned with studying the influences of different cultures on brain anatomy and function. In this study, it was examined whether different cultural or genetic influences might influence ... ...

    Title translation Unterschiedliche Merkmale im Ruhe-EEG bei Kindern aus der Schweiz und Saudi-Arabien
    Abstract Background: Cultural neuroscience is an emerging research field concerned with studying the influences of different cultures on brain anatomy and function. In this study, it was examined whether different cultural or genetic influences might influence the resting state electroencephalogram (EEG) in young children (mean age 10 years) from Switzerland and Saudi Arabia. Methods: Resting state EEG recordings were obtained from relatively large groups of healthy children (95 healthy Swiss children and 102 Saudi Arabian children). These EEG data were analyzed using group independent components analyses (gICA) and conventional analyses of spectral data, together with estimations of the underlying intracortical sources, using LORETA software. Results: Many similarities were identified, but also some substantial differences with respect to the resting state EEG data. For Swiss children, stronger delta band power values in mesial frontal areas and stronger power values in three out of four frequency bands in occipital areas were found. For Saudi Arabian children, stronger alpha band power over the sensorimotor cortex were uncovered. The additionally measured theta/beta ratio (TBR) was similar for Swiss and Saudi Arabian children. Conclusions: The different EEG resting state features identified, are discussed in the context of different cultural experiences and possible genetic influences. In addition, the importance of using appropriate EEG databases when comparing resting state EEG features between groups is emphasized.
    Keywords Child Characteristics ; Culture (Anthropological) ; Electrical Activity ; Electroencephalography ; Elektrische Aktivität ; Elektroenzephalographie ; Genetics ; Genetik ; Kindermerkmale ; Kultur (Anthropologie) ; Sociocultural Factors ; Soziokulturelle Faktoren
    Language English
    Document type Article
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    Database PSYNDEX

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  7. Article: O kompleksnoĭ otsenke zagriaznennosti atmosfernogo vozdukha.

    Evdokimov, S A

    Gigiena i sanitariia

    1990  , Issue 8, Page(s) 15–18

    Title translation Complex evaluation of atmospheric air pollution.
    MeSH term(s) Air Pollutants/analysis ; Air Pollution/analysis ; Air Pollution/statistics & numerical data ; Humans ; Mathematics ; Maximum Allowable Concentration ; Models, Theoretical ; USSR ; Urban Health/standards
    Chemical Substances Air Pollutants
    Language Russian
    Publishing date 1990-08
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 410437-7
    ISSN 0016-9900
    ISSN 0016-9900
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  8. Article: [Developmental features of the brain bioelectrical activity in children with remote consequences of a perinatal lesion of the CNS. II. EEG typology in normal and mental disorders].

    Kozhushko, N Iu / Ponomarev, V A / Matveev, Iu K / Evdokimov, S A

    Fiziologiia cheloveka

    2011  Volume 37, Issue 3, Page(s) 5–12

    Abstract: This research represents EEG - investigation by children with remote consequences of perinatal CNS pathology. Its described the different EEG types in normal and mental disorders in children. Its showed a early EEG - markers of abnormal ontogenesis in ... ...

    Abstract This research represents EEG - investigation by children with remote consequences of perinatal CNS pathology. Its described the different EEG types in normal and mental disorders in children. Its showed a early EEG - markers of abnormal ontogenesis in longitudinal study. The data obtained gives to prevent a negative dynamic of mental and speech development (learning disability, motor alalia, autism).
    MeSH term(s) Autistic Disorder/physiopathology ; Brain Mapping/methods ; Child ; Child, Preschool ; Electrocardiography ; Female ; Humans ; Infant ; Learning Disorders/physiopathology ; Male
    Language Russian
    Publishing date 2011-05
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 194077-6
    ISSN 0131-1646
    ISSN 0131-1646
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  9. Article: [Analysis of independent components for event-related potentials from patients with an established diagnosis of schizophrenia, obsessive-compulsive and depressive disorders].

    Evdokimov, S A / Pronina, M V / Poliakova, G Iu / Ponomarev, V A / Poliakov, Iu I / Kropotov, Iu D

    Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova

    2014  Volume 64, Issue 5, Page(s) 500–509

    Abstract: We investigated the possibility to classify data from patients with different psychiatric disorders on the base of physiological measures of the brain activity. Event-related potentials during the execution of GO/NOGO task were recorded from age matched ... ...

    Abstract We investigated the possibility to classify data from patients with different psychiatric disorders on the base of physiological measures of the brain activity. Event-related potentials during the execution of GO/NOGO task were recorded from age matched groups of patients with schizophrenia, major depression and obsessive-compulsive disorder. Separation of independent components for event-related potentials was performed by applying Independent Component Analysis method. Picked out components were used in the method of discriminant analysis to classify the data according to clinical diagnosis. Discriminant analysis of components for event-related potentials allows classifying the data of patients with a suitable amount of matches with an established diagnosis.
    MeSH term(s) Adult ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/physiopathology ; Diagnosis, Differential ; Discriminant Analysis ; Electroencephalography ; Evoked Potentials/physiology ; Female ; Frontal Lobe/physiopathology ; Humans ; Male ; Middle Aged ; Obsessive-Compulsive Disorder/diagnosis ; Obsessive-Compulsive Disorder/physiopathology ; Occipital Lobe/physiopathology ; Parietal Lobe/physiopathology ; Psychological Tests ; Reaction Time ; Schizophrenia/diagnosis ; Schizophrenia/physiopathology ; Task Performance and Analysis
    Language Russian
    Publishing date 2014-09
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 414800-9
    ISSN 0044-4677
    ISSN 0044-4677
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  10. Article: [The ratio between the phasic and tonic components of the frontal midline theta rhythm in the attention test].

    Evdokimov, S A / Kropotov, Iu D / Miuller, A / Tereshchenko, E P

    Fiziologiia cheloveka

    2006  Volume 32, Issue 6, Page(s) 5–12

    MeSH term(s) Adolescent ; Attention/physiology ; Child ; Female ; Frontal Lobe/physiology ; Humans ; Male ; Neuropsychological Tests ; Theta Rhythm
    Language Russian
    Publishing date 2006-11
    Publishing country Russia (Federation)
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 194077-6
    ISSN 0131-1646
    ISSN 0131-1646
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