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  1. Article ; Online: Prevalence and impact of Eustachian valve on the diagnosis of patent foramen ovale in patients ventilated for an acute respiratory distress syndrome.

    Sanchez, Florence / Goudelin, Marine / Evrard, Bruno / Vignon, Philippe

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 392

    MeSH term(s) Humans ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/epidemiology ; Prevalence ; Echocardiography, Transesophageal ; Vena Cava, Inferior/diagnostic imaging ; Respiratory Distress Syndrome/epidemiology ; Respiratory Distress Syndrome/therapy
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Letter
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04670-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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  2. Article ; Online: The Aortic Pulsatility Index: A New Sign of Severe Acute Aortic Regurgitation.

    Sanchez, Florence / Goudelin, Marine / Evrard, Bruno / Vignon, Philippe

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2022  Volume 35, Issue 9, Page(s) 1006–1007

    MeSH term(s) Aorta/diagnostic imaging ; Aortic Valve Insufficiency/diagnostic imaging ; Blood Flow Velocity ; Humans
    Language English
    Publishing date 2022-04-27
    Publishing country United States
    Document type Letter
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2022.04.008
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    Zs.A 2638: Show issues Location:
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  3. Article ; Online: Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening.

    Evrard, Bruno / Goudelin, Marine / Giraudeau, Bruno / François, Bruno / Vignon, Philippe

    Intensive care medicine

    2022  Volume 48, Issue 6, Page(s) 765–767

    MeSH term(s) COVID-19/complications ; Heart Failure ; Humans ; Respiratory Distress Syndrome/etiology ; SARS-CoV-2
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06730-0
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    Zs.A 1089: Show issues Location:
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  4. Article ; Online: Transesophageal Echocardiography Remains Essential and Safe during Prone Ventilation for Hemodynamic Monitoring of Patients with COVID-19.

    Evrard, Bruno / Goudelin, Marine / Vignon, Philippe

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2020  Volume 33, Issue 8, Page(s) 1057–1059

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Echocardiography ; Echocardiography, Transesophageal ; Hemodynamic Monitoring ; Hemodynamics ; Humans ; Pandemics ; Pneumonia, Viral ; Respiration, Artificial ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2020.05.018
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  5. Article ; Online: Left ventricular overloading is the leading mechanism in extubation failure of patients at high-risk of weaning-induced pulmonary edema.

    Goudelin, Marine / Evrard, Bruno / Vignon, Philippe

    Intensive care medicine

    2020  Volume 46, Issue 10, Page(s) 1962–1964

    MeSH term(s) Airway Extubation/adverse effects ; Critical Care ; Echocardiography ; Humans ; Pulmonary Edema/etiology ; Ventilator Weaning ; Weaning
    Keywords covid19
    Language English
    Publishing date 2020-08-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06201-4
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  6. Article ; Online: Severe Acute Cor Pulmonale in Patients with COVID-19 Acute Respiratory Distress Syndrome: Caution with Left Turn.

    Evrard, Bruno / Goudelin, Marine / Vaidie, Julien / Fedou, Anne-Laure / Vignon, Philippe

    American journal of respiratory and critical care medicine

    2022  Volume 205, Issue 8, Page(s) 961–964

    MeSH term(s) COVID-19/complications ; Heart Failure ; Humans ; Hypertension, Pulmonary ; Pulmonary Heart Disease/etiology ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202107-1568LE
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  7. Article ; Online: Diagnostic, prognostic and clinical value of left ventricular radial strain to identify paradoxical septal motion in ventilated patients with the acute respiratory distress syndrome: an observational prospective multicenter study.

    Evrard, Bruno / Woillard, Jean-Baptiste / Legras, Annick / Bouaoud, Misylias / Gourraud, Maeva / Humeau, Antoine / Goudelin, Marine / Vignon, Philippe

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 424

    Abstract: Background: Acute cor pulmonale (ACP) is prognostic in patients with acute respiratory distress syndrome (ARDS). Identification of paradoxical septal motion (PSM) using two-dimensional echocardiography is highly subjective. We sought to describe feature- ...

    Abstract Background: Acute cor pulmonale (ACP) is prognostic in patients with acute respiratory distress syndrome (ARDS). Identification of paradoxical septal motion (PSM) using two-dimensional echocardiography is highly subjective. We sought to describe feature-engineered metrics derived from LV radial strain changes related to PSM in ARDS patients with ACP of various severity and to illustrate potential diagnostic and prognostic yield.
    Methods: This prospective bicentric study included patients under protective ventilation for ARDS related to COVID-19 who were assessed using transesophageal echocardiography (TEE). Transgastric short-axis view at mid-papillary level was used to visually grade septal motion, using two-dimensional imaging, solely and combined with LV radial strain: normal (grade 0), transient end-systolic septal flattening (grade 1), prolonged end-systolic septal flattening or reversed septal curvature (grade 2). Inter-observer variability was calculated. Feature engineering was performed to calculate the time-to-peak and area under the strain curve in 6 LV segments. In the subset of patients with serial TEE examinations, a multivariate Cox model analysis accounting for new-onset of PSM as a time-dependent variable was used to identify parameters associated with ICU mortality.
    Results: Overall, 310 TEE examinations performed in 182 patients were analyzed (age: 67 [60-72] years; men: 66%; SAPSII: 35 [29-40]). Two-dimensional assessment identified a grade 1 and grade 2 PSM in 100 (32%) and 48 (15%) examinations, respectively. Inter-rater reliability was weak using two-dimensional imaging alone (kappa = 0.49; 95% CI 0.40-0.58; p < 0.001) and increased with associated LV radial strain (kappa = 0.84, 95% CI 0.79-0.90, p < 0.001). The time-to-peak of mid-septal and mid-lateral segments occurred significantly later in systole and increased with the grade of PSM. Similarly, the area under the strain curve of these segments increased significantly with the grade of PSM, compared with mid-anterior or mid-inferior segments. Severe acute cor pulmonale with a grade 2 PSM was significantly associated with mortality. Requalification in an upper PSM grade using LV radial strain allowed to better identify patients at risk of death (HR: 6.27 [95% CI 2.28-17.2] vs. 2.80 [95% CI 1.11-7.09]).
    Conclusions: In objectively depicting PSM and quantitatively assessing its severity, TEE LV radial strain appears as a valuable adjunct to conventional two-dimensional imaging.
    MeSH term(s) Aged ; Humans ; Male ; Hypertension, Pulmonary ; Prognosis ; Prospective Studies ; Pulmonary Heart Disease ; Reproducibility of Results ; Respiration, Artificial/adverse effects ; Respiratory Distress Syndrome/diagnostic imaging ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/complications ; Ventricular Dysfunction, Left ; Female ; Middle Aged
    Language English
    Publishing date 2023-11-02
    Publishing country England
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04716-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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  8. Article: Right ventricular injury in patients with COVID-19-related ARDS eligible for ECMO support: a multicenter retrospective study.

    Petit, Matthieu / Bouaoud, Misylias / Jullien, Edouard / Joseph, Adrien / Evrard, Bruno / Charron, Cyril / Daulasim, Anousone / Legras, Annick / Gourraud, Maeva / Goudelin, Marine / Vignon, Philippe / Vieillard-Baron, Antoine

    Annals of intensive care

    2024  Volume 14, Issue 1, Page(s) 40

    Abstract: Background: Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optimal criteria to select target ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optimal criteria to select target patients remain unknown. Our hypothesis is that evaluation of right ventricular (RV) function could be helpful. The aims of our study were to report the incidence and outcomes of patients eligible for ECMO according to EOLIA criteria, and to identify a subgroup of patients with RV injury, which could be a target for ECMO.
    Methods: Retrospective observational study involving 3 French intensive care units (ICUs) of teaching hospitals. Patients with confirmed SARS-CoV-2 infection between March 2020 and March 2021, presenting ARDS and with available echocardiography, were included. Patients were classified in three groups according to whether or not they met the EOLIA criteria and the presence of RV injury (RVI) ("EOLIA -", "EOLIA + RVI -" and "EOLIA + RVI + "). RVI was defined by the association of RV to left ventricular end-diastolic area ratio > 0.8 and paradoxical septal motion. Kaplan-Meier survival curves were used to analyze outcome as well as a Cox model for 90 day mortality.
    Results: 915 patients were hospitalized for COVID-19, 418 of them with ARDS. A total of 283 patients with available echocardiography were included. Eighteen (6.3%) patients received ECMO. After exclusion of these patients, 107 (40.5%) were classified as EOLIA -, 126 (47.5%) as EOLIA + RVI -, and 32 (12%) as EOLIA + RVI + . Ninety-day mortality was 21% in the EOLIA-group, 44% in the EOLIA + RVI-group, and 66% in the EOLIA + RVI + group (p < 0.001). After adjustment, RVI was statistically associated with 90-day mortality (HR = 1.92 [1.10-3.37]).
    Conclusions: Among COVID-19-associated ARDS patients who met the EOLIA criteria, those with significant RV pressure overload had a particularly poor outcome. This subgroup may be a more specific target for ECMO. This represented 12% of our cohort compared to 60% of patients who met the EOLIA criteria only. How the identification of this high-risk subset of patients translates into patient-centered outcomes remains to be evaluated.
    Language English
    Publishing date 2024-03-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-024-01256-8
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  9. Article ; Online: Hemodynamic response to prone ventilation in COVID-19 patients assessed with 3D transesophageal echocardiography.

    Evrard, Bruno / Goudelin, Marine / Fedou, Anne-Laure / Vignon, Philippe

    Intensive care medicine

    2020  Volume 46, Issue 11, Page(s) 2099–2101

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Echocardiography, Three-Dimensional ; Hemodynamics ; Humans ; Pandemics ; Patient Positioning ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Respiration, Artificial ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06217-w
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  10. Article: Assessment of Right Ventricular Mechanics by 3D Transesophageal Echocardiography in the Early Phase of Acute Respiratory Distress Syndrome.

    Evrard, Bruno / Lakatos, Bálint Károly / Goudelin, Marine / Tősér, Zoltán / Merkely, Béla / Vignon, Philippe / Kovács, Attila

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 861464

    Abstract: Aim: To compare global and axial right ventricular ejection fraction in ventilated patients for moderate-to-severe acute respiratory distress syndrome (ARDS) secondary to early SARS-CoV-2 pneumonia or to other causes, and in ventilated patients without ... ...

    Abstract Aim: To compare global and axial right ventricular ejection fraction in ventilated patients for moderate-to-severe acute respiratory distress syndrome (ARDS) secondary to early SARS-CoV-2 pneumonia or to other causes, and in ventilated patients without ARDS used as reference.
    Methods: Retrospective single-center cross-sectional study including 64 ventilated patients: 21 with ARDS related to SARS-CoV-2 (group 1), 22 with ARDS unrelated to SARS-CoV-2 (group 2), and 21 without ARDS (control group). Real-time three-dimensional transesophageal echocardiography was performed for hemodynamic assessment within 24 h after admission. Contraction pattern of the right ventricle was decomposed along the three anatomically relevant axes. Relative contribution of each spatial axis was evaluated by calculating ejection fraction along each axis divided by the global right ventricular ejection fraction.
    Results: Global right ventricular ejection fraction was significantly lower in group 2 than in both group 1 and controls [median: 43% (25-75th percentiles: 40-57) vs. 58% (55-62) and 65% (56-68), respectively:
    Conclusion: During early hemodynamic assessment, the right ventricular systolic function appears more impaired in ARDS unrelated to SARS-CoV-2 when compared to early stage SARS-CoV-2 ARDS. Radial shortening appears more involved than longitudinal and anteroposterior shortening in patients with ARDS unrelated to SARS-CoV-2 and decreased right ventricular ejection fraction.
    Language English
    Publishing date 2022-05-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.861464
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