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  1. Book ; Thesis: Diagnostik und Therapieotionen bei Gallengangskomplikationen nach orthotoper Lebertransplantation

    Förtsch, Thomas

    eine retrospektive Analyse von 175 Transplantationen

    2003  

    Author's details vorgelegt von Thomas Frank Förtsch
    Language German
    Size 79 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen-Nürnberg, Univ., Diss., 2003
    HBZ-ID HT013643231
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 E 1450 order for loan Magazin

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  2. Article ; Online: Results of isolated limb perfusion for metastasized malignant melanoma.

    Schellerer, Vera S / Frenger, Johannes / Merkel, Susanne / Goehl, Jonas / Kersting, Stephan / Gruetzmann, Robert / Erdmann, Michael / Foertsch, Thomas

    Surgical oncology

    2021  Volume 38, Page(s) 101603

    Abstract: Background and objectives: Locoregional metastases are typical biological manifestations of advanced malignant melanomas. Treatment with hyperthermic isolated limb perfusion (HILP) should be considered in affected patients. In the present study, we have ...

    Abstract Background and objectives: Locoregional metastases are typical biological manifestations of advanced malignant melanomas. Treatment with hyperthermic isolated limb perfusion (HILP) should be considered in affected patients. In the present study, we have analyzed the results of HILPs performed in our department.
    Patients and methods: Eighty patients with locoregional metastases of the extremities received HILP at the Department of Surgery between January 2007 and December 2016. The mean follow-up was 38 months.
    Results: The study included 50 men and 30 women (mean age: 63 years). The median time between melanoma diagnosis and HILP was 25 months (range: 1-219 months). HILP was performed in curative (n = 45) and palliative (n = 35) intention. Seventy-five patients received a drug combination of melphalan/dactinomycin and five patients received a drug combination of melphalan/tumor necrosis factor-alpha. Remission rates were determined in 72 of 80 patients (90%) as follows: partial response n = 28, complete response n = 25, no response n = 19. Of the 25 patients with complete response, 13 patients developed a new tumor manifestation during follow-up (locoregional recurrences n = 4; distant metastases n = 3; both n = 6). The median overall survival rate was 33 months. Tumor stage influenced the survival rate significantly (p = 0.001). Patients with complete response showed a significantly better overall survival than patients with partial or no response (p = 0.016).
    Conclusion: HILP is an effective therapeutic option in patients with locoregional metastases. This procedure carries a certain risk of side effects and adverse events but overall results in good response rates. Therefore, HILP should be offered to selected patients based on an individual discussion, considering their health status and oncological prognosis.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Chemotherapy, Cancer, Regional Perfusion/mortality ; Combined Modality Therapy ; Extremities/pathology ; Female ; Follow-Up Studies ; Humans ; Hyperthermia, Induced/mortality ; Male ; Melanoma/pathology ; Melanoma/therapy ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/therapy ; Prognosis ; Retrospective Studies ; Survival Rate ; Young Adult
    Language English
    Publishing date 2021-05-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1107810-8
    ISSN 1879-3320 ; 0960-7404
    ISSN (online) 1879-3320
    ISSN 0960-7404
    DOI 10.1016/j.suronc.2021.101603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book: Apache verstehen und einsetzen

    Förtsch, Torgen

    für Einstieger und Fortgeschrittenen unter Unix/Linux und Windows

    2005  

    Author's details Torgen Förtsch
    Language German
    Size ca. 300 S
    Publishing place dpunkt
    Document type Book
    ISBN 3898643115 ; 9783898643115
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article ; Online: Biliary tract complications after orthotopic liver transplantation: still the "Achilles heel"?

    Perrakis, A / Förtsch, T / Schellerer, V / Hohenberger, W / Müller, V

    Transplantation proceedings

    2010  Volume 42, Issue 10, Page(s) 4154–4157

    Abstract: Postoperative biliary tract complications after liver transplantation (LT) still lead to early and late morbidity and mortality. Modern interventional endoscopic techniques can replace surgical repair as the first line of treatment. Nevertheless surgical ...

    Abstract Postoperative biliary tract complications after liver transplantation (LT) still lead to early and late morbidity and mortality. Modern interventional endoscopic techniques can replace surgical repair as the first line of treatment. Nevertheless surgical intervention plays an important role in specific situations. We performed a retrospective analysis of patients with biliary complications after LT over a 12-year period. We compared treatment programs based on duration and success rate. The rate of biliary complications was 24.5% (60/245). The side-to-side choledocholedochostomy (CDC) technique showed the significantly lowest rate. The rate of complications after hepaticojejunostomy (HJS) was considerably lower, albeit not significantly. Eighty-one percent of complications after CDC were treated with interventional endoscopy. The duration of treatment of strictures, was 10 times greater than that of leakages. Surgical repair was necessary for 19% of complications occurring after CDC. The treatment options after HJS largely comprised surgical repairs. From a surgical standpoint, choosing the correct method for biliary reconstruction and ensuring normal arterial flow are the best preventive techniques to avoid biliary complications. Over the past 10 years, the primary treatment regimen has moved from surgical repair to interventional endoscopy. Only when endoscopy fails, should one consider surgical repair. The treatment after HJS is still primarily surgical. Percutaneous transhepatic approaches should be avoided. Creation of an inspection stoma to allow endoscopic access is an option.
    MeSH term(s) Biliary Tract Diseases/etiology ; Humans ; Liver Transplantation/adverse effects ; Retrospective Studies
    Language English
    Publishing date 2010-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2010.09.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 835: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Thesis: Diagnostik und Therapieoptionen bei Gallengangskomplikationen nach orthotoper Lebertransplantation

    Förtsch, Thomas

    eine retrospektive Analyse von 175 Transplantationen

    2003  

    Author's details vorgelegt von Thomas Frank Förtsch
    Language German
    Size 1 Mikrofiche, Ill., graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Nürnberg, Univ., Diss--Erlangen, 2003
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

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  6. Article ; Online: Vertical Scanning Interferometry for Label-Free Detection of Peptide-Antibody Interactions.

    Palermo, Andrea / Thelen, Richard / Weber, Laura K / Foertsch, Tobias / Rentschler, Simone / Hackert, Verena / Syurik, Julia / Nesterov-Mueller, Alexander

    High-throughput

    2019  Volume 8, Issue 2

    Abstract: Peptide microarrays are a fast-developing field enabling the mapping of linear epitopes in the immune response to vaccinations or diseases and high throughput studying of protein-protein interactions. In this respect, a rapid label-free measurement of ... ...

    Abstract Peptide microarrays are a fast-developing field enabling the mapping of linear epitopes in the immune response to vaccinations or diseases and high throughput studying of protein-protein interactions. In this respect, a rapid label-free measurement of protein layer topographies in the array format is of great interest but is also a great challenge due to the extremely low aspect ratios of the peptide spots. We have demonstrated the potential of vertical scanning interferometry (VSI) for a detailed morphological analysis of peptide arrays and binding antibodies. The VSI technique is shown to scan an array area of 5.1 square millimeters within 3⁻4 min at a resolution of 1.4 μm lateral and 0.1 nm vertical in the full automation mode. Topographies obtained by VSI do match the one obtained by AFM measurements, demonstrating the accuracy of the technique. A detailed topology of peptide-antibody layers on single spots was measured. Two different measurement regions are distinguished according to the antibody concentration. In the case of weakly diluted serum, the thickness of the antibody layer is independent of the serum dilution and corresponds to the physical thickness of the accumulated antibody layer. In strongly diluted serum, the thickness measured via VSI is linearly proportional to the serum dilution.
    Language English
    Publishing date 2019-03-27
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2571-5135
    ISSN (online) 2571-5135
    DOI 10.3390/ht8020007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Computed Tomography-Guided Percutaneous Gastrostomy/Jejunostomy for Feeding and Decompression.

    Albrecht, Heinz / Hagel, Alexander F / Schlechtweg, Philipp / Foertsch, Thomas / Neurath, Markus F / Mudter, Jonas

    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    2017  Volume 32, Issue 2, Page(s) 212–218

    Abstract: Background: An effective method for long-term enteral feeding or stomach decompression is the use of a percutaneous gastrostomy (PEG) or sometimes jejunostomy (PEJ). Under certain circumstances (eg, inadequate transillumination), endoscopic placement of ...

    Abstract Background: An effective method for long-term enteral feeding or stomach decompression is the use of a percutaneous gastrostomy (PEG) or sometimes jejunostomy (PEJ). Under certain circumstances (eg, inadequate transillumination), endoscopic placement of PEG/PEJ tubes is impossible. In these cases, computed tomography (CT)-guided PEG/PEJ may represent an alternative technique. In this study, we evaluate indications, results, and complications of CT-guided PEG/PEJ.
    Materials and methods: A total of 102 consecutive referred patients were enrolled in the study. Patients came to the endoscopy unit of our department to undergo a CT-guided PEG/PEJ for long-term intragastric/intrajejunal feeding (n = 57) or decompression (n = 45). The majority (n = 98) received a pull-through PEG/PEJ with simultaneous gastroscopy/jejunoscopy. Dose length product and the effective dose for every patient were calculated.
    Results: PEG/PEJ tube placement was successful in 87.3% (89 of 102). Feeding PEG/PEJ tube placement was successfully completed in 91.2% (52 of 57); decompressive PEG/PEJ tube placement was likewise successfully completed in 82.2% (37 of 45). No procedure-related mortality was observed. Minor complications (eg, tube dysfunction, local bleeding, minimal leakage, local skin infection) were observed in 13 patients. The complication rate was similar between the feeding and decompression groups ( P = .9).
    Conclusions: CT-guided PEG/PEJ is a feasible and safe method with a low procedure-related morbidity rate for patients where endoscopic placement via transillumination is not successful. Thus, the procedure is an attractive alternative to surgical tube placement. Long-term complications, mainly tube disturbances, can be treated easily.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Decompression ; Endoscopy, Gastrointestinal ; Enteral Nutrition ; Feasibility Studies ; Female ; Follow-Up Studies ; Gastrostomy/methods ; Humans ; Intubation, Gastrointestinal ; Jejunostomy/methods ; Male ; Middle Aged ; Retrospective Studies ; Stomach/diagnostic imaging ; Stomach/pathology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645074-x
    ISSN 1941-2452 ; 0884-5336
    ISSN (online) 1941-2452
    ISSN 0884-5336
    DOI 10.1177/0884533616653806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2451: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Book ; Thesis: Euclidean rank and hyperbolic rank of Hadamard manifolds

    Foertsch, Thomas

    2002  

    Author's details von Thomas Foertsch
    Language English
    Size II, 81 S, graph. Darst, 21 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Zürich, 2002
    Note Zsfassung in dt. Sprache
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book ; Thesis: Euclidean rank and hyperbolic rank of Hadamard manifolds

    Foertsch, Thomas

    2002  

    Author's details von Thomas Foertsch
    Language English
    Size II, 81 S, graph. Darst, 21 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Zürich, 2002
    Note Zsfassung in dt. Sprache
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Article ; Conference proceedings: Einsatz des over-the-scope-clips (OTSC) zur Behandlung einer Colon-Perforation verursachte eine Dünndarmfixation mit nachfolgender chirurgischer Resektion

    Albrecht, H / Nägel, A / Hagel, A / Rösler, W / Förtsch, T / Neurath, MF / Raithel, M

    Endoskopie heute

    2014  

    Abstract: Fragestellung: Der over-the-scope-clip (OTSC; Ovesco Endoscopy, Tübingen, Germany) ist relativ neues Verfahren zum endoskopischen Verschluss großer Defekte im Gastrointestinaltrakt [1]. Dieses Vorgehen ist eine einfache und wenig invasive Technik, die ... ...

    Event/congress 44. Kongress der Deutschen Gesellschaft für Endoskopie und Bildgebende Verfahren e.V., Hamburg, 2014
    Abstract Fragestellung: Der over-the-scope-clip (OTSC; Ovesco Endoscopy, Tübingen, Germany) ist relativ neues Verfahren zum endoskopischen Verschluss großer Defekte im Gastrointestinaltrakt [1]. Dieses Vorgehen ist eine einfache und wenig invasive Technik, die bei erfolgreichem Verschluss zur Vermeidung aufwendiger chirurgischer Eingriffe beiträgt. Dennoch birgt auch diese Methode Risiken, wie z.B. Darmwandverletzungen oder Ausbildung von Stenosen durch den OTSC.
    Ziel: Darstellung einer schweren Nebenwirkung durch den Einsatz des OTSC bei einer Colonperforation und kritische Überprüfung der publizierten Ergebnisse zum Nebenwirkungsprofil des OTSC und zur Aufklärung über Risiken der Methode.
    Methodik: Systematische Literaturrecherche über MEDLINE zum Thema OTSC-Applikation, intestinale Perforation und Komplikationen und Präsentation eines Falles aus der eigenen Klinik.
    Ergebnis: Bei den bislang publizierten Berichten und Studien zum Einsatz des OTSC fand sich eine gute Verschlussrate von ca. 89% [2]. Dabei wurden zumeist nur geringe Nebenwirkungsfrequenzen berichtet. Wir berichten hier erstmals von einer möglichen, aber schweren Komplikation beim Einsatz des OTSC durch Fixation angrenzenden Gewebes aus dem Dünndarm. Dies führte im Verlauf zu einer Beschwerdezunahme im Sinne von Bauchschmerzen. In der aufgrund dessen durchgeführten Röntgen-Aufnahme zeigte sich ausgeprägt freie Luft im Abdomen. Daher wurde letztendlich eine offene Sigmaresektion und Übernähung der Dünndarmperforation durchgeführt. Das erwünschte Ziel der Vermeidung eines chirurgischen Perforationsverschlusses konnte in dem präsentierten Fall nicht erreicht werden. Beim Einsatz des OTSC sollten daher mögliche Komplikationen in Betracht gezogen werden und darüber aufgeklärt werden. Bei der jeweils benutzten Anwendungsmethode (Kappe, Saugstärke, Twin Grasper oder Anker) sind im Einzellfall die Induktion von Blutung, Aufreissen des Perforationsostiums, Fixation angrenzender Gewebeanteile etc. kritisch zu überprüfen.
    References: 1] Mönkemüller K et al., (2013), Multipurpose use of the 'bear claw' (over-the-scope-clip system) to treat endoluminal gastrointestinal disorders, Dig Endosc. [2] Voermans RP et al., (2012), Efficacy of endoscopic closure of acute perforations of the gastrointestinal tract, Clin Gastroenterol Hepatol.
    Language German
    Publishing date 2014-03-21
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2082669-2
    ISSN 1439-2577 ; 0933-811X
    ISSN (online) 1439-2577
    ISSN 0933-811X
    DOI 10.1055/s-0034-1371062
    Database Thieme publisher's database

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