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  1. Article ; Online: Advances in immunology and rheumatoid arthritis pathogenesis

    A. Sili Scavalli / M. Catuogno / D. Bompanone / F. Barone / G. Valesini

    Reumatismo, Vol 56, Iss 1s, Pp 9-

    2011  Volume 20

    Abstract: The pathogenesis of Rheumatoid Arthritis (RA) is still largely unknown. From the seminal experimental studies, suggesting a multifactorial mechanism leaded by an antigen specific activation, the direct role of innate immunity in the disease progression ... ...

    Abstract The pathogenesis of Rheumatoid Arthritis (RA) is still largely unknown. From the seminal experimental studies, suggesting a multifactorial mechanism leaded by an antigen specific activation, the direct role of innate immunity in the disease progression has been recently emphasized. In the natural history of RA, characterized by the three phases of the induction, maintenance and tissue destruction, innate immunity seems to be the central player. On the other hands the recent advances about the molecules involved in the T lymphocyte activation, the T cell role in the mechanism of erosion, and the studies about chemochines in the homing and angiogenesis processes support the theory of an antigen specific activation of the adaptive immune system. Therefore, during RA, the pathogenesis of sinovitis and erosions comes from independent pathways involving either innate and adaptive immunity resulting in the final induction of the articular damage.
    Keywords Medicine ; R ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2011-09-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Effects of different enrichment devices on some welfare indicators of post-weaned undocked piglets

    Nannoni, E / A. Ferrari / E. Trevisi / F. Barone / G. Martelli / L. Sardi / M. Vitali / M.L. Bacci / S. Barbieri

    Applied animal behaviour science. 2016 Nov., v. 184

    2016  

    Abstract: Two experimental trials were carried out in order to test the effectiveness of different environmental enrichments in improving the welfare of weaned pigs. A total of 120 undocked piglets was used. In trial one, group C1 received a metal chain and group ... ...

    Abstract Two experimental trials were carried out in order to test the effectiveness of different environmental enrichments in improving the welfare of weaned pigs. A total of 120 undocked piglets was used. In trial one, group C1 received a metal chain and group WL a wooden log mounted on a frame. In trial two, the enrichments proposed were a hanging chain (group C2), an edible block (group ED) and a wooden briquette (group WB) mounted on a frame. The effectiveness of the enrichments was assessed in terms of animal behaviour, cortisol from bristles, hematologic and hematic profiles, cutaneous (skin and tail) lesions. Growth parameters were also recorded. Although some differences were detected in growth parameters in trial 1 (with C1 group having better productive outcomes than WL group) and some minor differences were observed in animal behaviour in both trials, the overall welfare status did not differ among the experimental groups. On the other hand, no welfare issues emerged in groups C1 and C2, receiving the enrichment device which is generally believed to be scarcely attractive, i.e. the hanging chain. We can therefore conclude that, if no managerial errors are made (floor space availability, feed inadequacy, group stability, microclimate, illumination), under the tested experimental conditions, hanging chains can provide a sufficient environmental enrichment for undocked piglets, even when compared to more attractive enrichments (e.g. an edible block).
    Keywords animal behavior ; cortisol ; environmental enrichment ; lesions (animal) ; lighting ; microclimate ; piglets ; setae (animal) ; tail ; wood logs
    Language English
    Dates of publication 2016-11
    Size p. 25-34.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 591645-8
    ISSN 0168-1591
    ISSN 0168-1591
    DOI 10.1016/j.applanim.2016.08.004
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Mortalità per tumore pleurico e peritoneale in una coorte di lavoratori del cemento amianto, dopo lunghi periodi di latenza: valutazione di un possibile ruolo della clearance delle fibre.

    Adesi, F Barone / Ferrante, D / Bertolotti, M / Todesco, A / Mirabelli, D / Terracini, B / Magnani, C

    Giornale italiano di medicina del lavoro ed ergonomia

    2007  Volume 29, Issue 3 Suppl, Page(s) 346–348

    Abstract: The multistage theory of carcinogenesis assumes rates of mesothelioma increasing monotonically as a function of time since first exposure (TSFE) to asbestos. However, some authors have suggested that the increase in mesothelioma rate with TSFE might be ... ...

    Title translation Mortality from pleural and peritoneal cancer in a cohort of asbestos workers, many years after start of the exposure: possible role of fibers clearance.
    Abstract The multistage theory of carcinogenesis assumes rates of mesothelioma increasing monotonically as a function of time since first exposure (TSFE) to asbestos. However, some authors have suggested that the increase in mesothelioma rate with TSFE might be attenuated by clearance of asbestos from the lungs. We estimated mortality time trends from pleural and peritoneal cancer in a cohort of 3443 asbestos-cement workers. The role of asbestos clearance was explored using the traditional mesothelioma multistage model, generalized to include a term representing elimination over time. We observed 139 deaths from pleural and 56 from peritoneal cancer during the period 1950-2003. The rate of pleural cancer increased during the first 40 years of TSFE and reached a plateau thereafter. In contrast, the rate of peritoneal cancer increased monotonically with TSFE. The model allowing for asbestos elimination fitted the data better than the traditional model for pleural (p = 0.02) but not for peritoneal cancer (p = 0.22). The risk for pleural cancer, rather than showing an indefinite increase, might reach a plateau when a sufficiently long time has elapsed since exposure. The different trends for pleural and peritoneal cancer might be related to clearance of the asbestos from the workers' lungs.
    MeSH term(s) Asbestos/adverse effects ; Female ; Humans ; Male ; Mineral Fibers/adverse effects ; Occupational Diseases/epidemiology ; Occupational Diseases/etiology ; Occupational Diseases/mortality ; Occupational Exposure/adverse effects ; Peritoneal Neoplasms/epidemiology ; Peritoneal Neoplasms/etiology ; Peritoneal Neoplasms/mortality ; Pleural Neoplasms/epidemiology ; Pleural Neoplasms/etiology ; Pleural Neoplasms/mortality ; Time Factors
    Chemical Substances Mineral Fibers ; Asbestos (1332-21-4)
    Language Italian
    Publishing date 2007-07
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 603103-1
    ISSN 1592-7830 ; 0391-9889
    ISSN 1592-7830 ; 0391-9889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift During the LIGO-Virgo Run O3a

    Collaboration, The LIGO Scientific / R.Abbott, the Virgo Collaboration / T.D.Abbott, / S.Abraham, / F.Acernese, / K.Ackley, / C.Adams, / R.X.Adhikari, / V.B.Adya, / C.Affeldt, / M.Agathos, / K.Agatsuma, / N.Aggarwal, / O.D.Aguiar, / A.Aich, / L.Aiello, / A.Ain, / P.Ajith, / G.Allen, /
    A.Allocca, / P.A.Altin, / A.Amato, / S.Anand, / A.Ananyeva, / S.B.Anderson, / W.G.Anderson, / S.V.Angelova, / S.Ansoldi, / S.Antier, / S.Appert, / K.Arai, / M.C.Araya, / J.S.Areeda, / M.Arene, / N.Arnaud, / S.M.Aronson, / Y.Asali, / S.Ascenzi, / G.Ashton, / M.Assiduo, / S.M.Aston, / P.Astone, / F.Aubin, / P.Aufmuth, / K.AultONeal, / C.Austin, / V.Avendano, / S.Babak, / P.Bacon, / F.Badaracco, / M.K.M.Bader, / S.Bae, / A.M.Baer, / J.Baird, / F.Baldaccini, / G.Ballardin, / S.W.Ballmer, / A.Bals, / A.Balsamo, / G.Baltus, / S.Banagiri, / D.Bankar, / R.S.Bankar, / J.C.Barayoga, / C.Barbieri, / B.C.Barish, / D.Barker, / K.Barkett, / P.Barneo, / F.Barone, / B.Barr, / L.Barsotti, / M.Barsuglia, / D.Barta, / J.Bartlett, / I.Bartos, / R.Bassiri, / A.Basti, / M.Bawaj, / J.C.Bayley, / M.Bazzan, / B.B'ecsy, / M.Bejger, / I.Belahcene, / A.S.Bell, / D.Beniwal, / M.G.Benjamin, / J.D.Bentley, / F.Bergamin, / B.K.Berger, / G.Bergmann, / S.Bernuzzi, / C.P.L.Berry, / D.Bersanetti, / A.Bertolini, / J.Betzwieser, / R.Bhandare, / A.V.Bhandari, / A.Bianchi, / J.Bidler, / E.Biggs, / I.A.Bilenko, / G.Billingsley, / R.Birney, / O.Birnholtz, / S.Biscans, / M.Bischi, / S.Biscoveanu, / A.Bisht, / G.Bissenbayeva, / M.Bitossi, / M.A.Bizouard, / J.K.Blackburn, / J.Blackman, / C.D.Blair, / D.G.Blair, / R.M.Blair, / F.Bobba, / N.Bode, / M.Boer, / Y.Boetzel, / G.Bogaert, / F.Bondu, / E.Bonilla, / R.Bonnand, / P.Booker, / B.A.Boom, / R.Bork, / V.Boschi, / S.Bose, / V.Bossilkov, / J.Bosveld, / Y.Bouffanais, / A.Bozzi, / C.Bradaschia, / P.R.Brady, / A.Bramley, / M.Branchesi, / J.E.Brau, / M.Breschi, / T.Briant, / J.H.Briggs, / F.Brighenti, / A.Brillet, / M.Brinkmann, / P.Brockill, / A.F.Brooks, / J.Brooks, / D.D.Brown, / S.Brunett, / G.Bruno, / R.Bruntz, / A.Buikema, / T.Bulik, / H.J.Bulten, / A.Buonanno, / D.Buskulic, / R.L.Byer, / M.Cabero, / L.Cadonati, / G.Cagnoli, / C.Cahillane, / Bustillo, J.Calder'on / J.D.Callaghan, / T.A.Callister, / E.Calloni, / J.B.Camp, / M.Canepa, / Santoro, G.Caneva / K.C.Cannon, / H.Cao, / J.Cao, / G.Carapella, / F.Carbognani, / S.Caride, / M.F.Carney, / G.Carullo, / T.L.Carver, / Diaz, J.Casanueva / C.Casentini, / J.Castaneda, / S.Caudill, / M.Cavaglia, / F.Cavalier, / R.Cavalieri, / G.Cella, / P.Cerd'a-Dur'an, / E.Cesarini, / O.Chaibi, / K.Chakravarti, / C.Chan, / M.Chan, / S.Chao, / P.Charlton, / E.A.Chase, / E.Chassande-Mottin, / D.Chatterjee, / M.Chaturvedi, / H.Y.Chen, / X.Chen, / Y.Chen, / H.-P.Cheng, / C.K.Cheong, / H.Y.Chia, / F.Chiadini, / R.Chierici, / A.Chincarini, / A.Chiummo, / G.Cho, / H.S.Cho, / M.Cho, / N.Christensen, / Q.Chu, / S.Chua, / K.W.Chung, / S.Chung, / G.Ciani, / P.Ciecielag, / M.Cie'slar, / A.A.Ciobanu, / R.Ciolfi, / F.Cipriano, / A.Cirone, / F.Clara, / J.A.Clark, / P.Clearwater, / S.Clesse, / F.Cleva, / E.Coccia, / P.-F.Cohadon, / D.Cohen, / M.Colleoni, / C.G.Collette, / C.Collins, / M.Colpi, / M.Constancio, / L.Conti, / S.J.Cooper, / P.Corban, / T.R.Corbitt, / I.Cordero-Carri'on, / S.Corezzi, / K.R.Corley, / N.Cornish, / D.Corre, / A.Corsi, / S.Cortese, / C.A.Costa, / R.Cotesta, / M.W.Coughlin, / S.B.Coughlin, / J.-P.Coulon, / S.T.Countryman, / P.Couvares, / P.B.Covas, / D.M.Coward, / M.J.Cowart, / D.C.Coyne, / R.Coyne, / J.D.E.Creighton, / T.D.Creighton, / J.Cripe, / M.Croquette, / S.G.Crowder, / J.-R.Cudell, / T.J.Cullen, / A.Cumming, / R.Cummings, / L.Cunningham, / E.Cuoco, / M.Curylo, / Canton, T.Dal / G.D'alya, / A.Dana, / L.M.Daneshgaran-Bajastani, / B.D'Angelo, / S.L.Danilishin, / S.D'Antonio, / K.Danzmann, / C.Darsow-Fromm, / A.Dasgupta, / L.E.H.Datrier, / V.Dattilo, / I.Dave, / M.Davier, / G.S.Davies, / D.Davis, / E.J.Daw, / D.DeBra, / M.Deenadayalan, / J.Degallaix, / Laurentis, M.De / S.Del'eglise, / M.Delfavero, / Lillo, N.De / Pozzo, W.Del / L.M.DeMarchi, / V.D'Emilio, / N.Demos, / T.Dent, / Pietri, R.De / Rosa, R.De / Rossi, C.De / R.DeSalvo, / Varona, O.de / S.Dhurandhar, / M.C.D'iaz, / M.Diaz-Ortiz, / T.Dietrich, / Fiore, L.Di / Fronzo, C.Di / Giorgio, C.Di / Giovanni, F.Di / Giovanni, M.Di / Girolamo, T.Di / Lieto, A.Di / B.Ding, / Pace, S.Di / Palma, I.Di / Renzo, F.Di / A.K.Divakarla, / A.Dmitriev, / Z.Doctor, / F.Donovan, / K.L.Dooley, / S.Doravari, / I.Dorrington, / T.P.Downes, / M.Drago, / J.C.Driggers, / Z.Du, / J.-G.Ducoin, / P.Dupej, / O.Durante, / D.D'Urso, / S.E.Dwyer, / P.J.Easter, / G.Eddolls, / B.Edelman, / T.B.Edo, / O.Edy, / A.Effler, / P.Ehrens, / J.Eichholz, / S.S.Eikenberry, / M.Eisenmann, / R.A.Eisenstein, / A.Ejlli, / L.Errico, / R.C.Essick, / H.Estelles, / D.Estevez, / Z.B.Etienne, / T.Etzel, / M.Evans, / T.M.Evans, / B.E.Ewing, / V.Fafone, / S.Fairhurst, / X.Fan, / S.Farinon, / B.Farr, / W.M.Farr, / E.J.Fauchon-Jones, / M.Favata, / M.Fays, / M.Fazio, / J.Feicht, / M.M.Fejer, / F.Feng, / E.Fenyvesi, / D.L.Ferguson, / A.Fernandez-Galiana, / I.Ferrante, / E.C.Ferreira, / T.A.Ferreira, / F.Fidecaro, / I.Fiori, / D.Fiorucci, / M.Fishbach, / R.P.Fisher, / R.Fittipaldi, / M.Fitz-Axen, / V.Fiumara, / R.Flaminio, / E.Floden, / E.Flynn, / H.Fong, / J.A.Font, / P.W.F.Forsyth, / J.-D.Fournier, / S.Frasca, / F.Frasconi, / Z.Frei, / A.Freise, / R.Frey, / V.Frey, / P.Fritschel, / V.V.Frolov, / G.Fronze, / P.Fulda, / M.Fyffe, / H.A.Gabbard, / B.U.Gadre, / S.M.Gaebel, / J.R.Gair, / S.Galaudage, / D.Ganapathy, / S.G.Gaonkar, / C.Garc'ia-Quir'os, / F.Garufi, / B.Gateley, / S.Gaudio, / V.Gayathri, / G.Gemme, / E.Genin, / A.Gennai, / D.George, / J.George, / L.Gergely, / S.Ghonge, / Ghosh, Abhirup / Ghosh, Archisman / S.Ghosh, / B.Giacomazzo, / J.A.Giaime, / K.D.Giardina, / D.R.Gibson, / C.Gier, / K.Gill, / J.Glanzer, / J.Gniesmer, / P.Godwin, / E.Goetz, / R.Goetz, / N.Gohlke, / B.Goncharov, / G.Gonz'alez, / A.Gopakumar, / S.E.Gossan, / M.Gosselin, / R.Gouaty, / B.Grace, / A.Grado, / M.Granata, / A.Grant, / S.Gras, / P.Grassia, / C.Gray, / R.Gray, / G.Greco, / A.C.Green, / R.Green, / E.M.Gretarsson, / H.L.Griggs, / G.Grignani, / A.Grimaldi, / S.J.Grimm, / H.Grote, / S.Grunewald, / P.Gruning, / G.M.Guidi, / A.R.Guimaraes, / G.Guix'e, / H.K.Gulati, / Y.Guo, / A.Gupta, / Gupta, Anchal / P.Gupta, / E.K.Gustafson, / R.Gustafson, / L.Haegel, / O.Halim, / E.D.Hall, / E.Z.Hamilton, / G.Hammond, / M.Haney, / M.M.Hanke, / J.Hanks, / C.Hanna, / M.D.Hannam, / O.A.Hannuksela, / T.J.Hansen, / J.Hanson, / T.Harder, / T.Hardwick, / K.Haris, / J.Harms, / G.M.Harry, / I.W.Harry, / R.K.Hasskew, / C.-J.Haster, / K.Haughian, / F.J.Hayes, / J.Healy, / A.Heidmann, / M.C.Heintze, / J.Heinze, / H.Heitmann, / F.Hellman, / P.Hello, / G.Hemming, / M.Hendry, / I.S.Heng, / E.Hennes, / J.Hennig, / M.Heurs, / S.Hild, / T.Hinderer, / S.Y.Hoback, / S.Hochheim, / E.Hofgard, / D.Hofman, / A.M.Holgado, / N.A.Holland, / K.Holt, / D.E.Holz, / P.Hopkins, / C.Horst, / J.Hough, / E.J.Howell, / C.G.Hoy, / Y.Huang, / M.T.Hubner, / E.A.Huerta, / D.Huet, / B.Hughey, / V.Hui, / S.Husa, / S.H.Huttner, / R.Huxford, / T.Huynh-Dinh, / B.Idzkowski, / A.Iess, / H.Inchauspe, / C.Ingram, / G.Intini, / J.-M.Isac, / M.Isi, / B.R.Iyer, / T.Jacqmin, / S.J.Jadhav, / S.P.Jadhav, / A.L.James, / K.Jani, / N.N.Janthalur, / P.Jaranowski, / D.Jariwala, / R.Jaume, / A.C.Jenkins, / J.Jiang, / G.R.Johns, / A.W.Jones, / D.I.Jones, / J.D.Jones, / P.Jones, / R.Jones, / R.J.G.Jonker, / L.Ju, / J.Junker, / C.V.Kalaghatgi, / V.Kalogera, / B.Kamai, / S.Kandhasamy, / G.Kang, / J.B.Kanner, / S.J.Kapadia, / S.Karki, / R.Kashyap, / M.Kasprzack, / W.Kastaun, / S.Katsanevas, / E.Katsavounidis, / W.Katzman, / S.Kaufer, / K.Kawabe, / F.K'ef'elian, / D.Keitel, / A.Keivani, / R.Kennedy, / J.S.Key, / S.Khadka, / F.Y.Khalili, / I.Khan, / S.Khan, / Z.A.Khan, / E.A.Khazanov, / N.Khetan, / M.Khursheed, / N.Kijbunchoo, / Kim, Chunglee / G.J.Kim, / J.C.Kim, / K.Kim, / W.Kim, / W.S.Kim, / Y.-M.Kim, / C.Kimball, / P.J.King, / M.Kinley-Hanlon, / R.Kirchhoff, / J.S.Kissel, / L.Kleybolte, / S.Klimenko, / T.D.Knowles, / E.Knyazev, / P.Koch, / S.M.Koehlenbeck, / G.Koekoek, / S.Koley, / V.Kondrashov, / A.Kontos, / N.Koper, / M.Korobko, / W.Z.Korth, / M.Kovalam, / D.B.Kozak, / V.Kringel, / N.V.Krishnendu, / A.Kr'olak, / N.Krupinski, / G.Kuehn, / A.Kumar, / P.Kumar, / Kumar, Rahul / Kumar, Rakesh / S.Kumar, / L.Kuo, / A.Kutynia, / B.D.Lackey, / D.Laghi, / E.Lalande, / T.L.Lam, / A.Lamberts, / M.Landry, / B.B.Lane, / R.N.Lang, / J.Lange, / B.Lantz, / R.K.Lanza, / Rosa, I.La / A.Lartaux-Vollard, / P.D.Lasky, / M.Laxen, / A.Lazzarini, / C.Lazzaro, / P.Leaci, / S.Leavey, / Y.K.Lecoeuche, / C.H.Lee, / H.M.Lee, / H.W.Lee, / J.Lee, / K.Lee, / J.Lehmann, / N.Leroy, / N.Letendre, / Y.Levin, / A.K.Y.Li, / J.Li, / K.li, / T.G.F.Li, / X.Li, / F.Linde, / S.D.Linker, / J.N.Linley, / T.B.Littenberg, / J.Liu, / X.Liu, / M.Llorens-Monteagudo, / R.K.L.Lo, / A.Lockwood, / L.T.London, / A.Longo, / M.Lorenzini, / V.Loriette, / M.Lormand, / G.Losurdo, / J.D.Lough, / C.O.Lousto, / G.Lovelace, / H.Luck, / D.Lumaca, / A.P.Lundgren, / Y.Ma, / R.Macas, / S.Macfoy, / M.MacInnis, / D.M.Macleod, / I.A.O.MacMillan, / A.Macquet, / Hernandez, I.Magana / F.Magana-Sandoval, / R.M.Magee, / 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    Abstract: We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 ... ...

    Abstract We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 UTC). 105 gamma-ray bursts were analyzed using a search for generic gravitational-wave transients; 32 gamma-ray bursts were analyzed with a search that specifically targets neutron star binary mergers as short gamma-ray burst progenitors. We describe a method to calculate the probability that triggers from the binary merger targeted search are astrophysical and apply that method to the most significant gamma-ray bursts in that search. We find no significant evidence for gravitational-wave signals associated with the gamma-ray bursts that we followed up, nor for a population of unidentified subthreshold signals. We consider several source types and signal morphologies, and report for these lower bounds on the distance to each gamma-ray burst.
    Keywords covid19
    Publisher ArXiv
    Document type Article
    Database COVID19

    Kategorien

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