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  1. Article: Predictors of Deterioration in Mental Well-Being and Quality of Life among Family Caregivers and Older People with Long-Term Care Needs during the COVID-19 Pandemic.

    Fabbietti, Paolo / Santini, Sara / Piccinini, Flavia / Giammarchi, Cinzia / Lamura, Giovanni

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 3

    Abstract: Background: During the COVID-19 pandemic, reduced access to care services and fear of infection prompted families to increase home care for their older relatives with long-term care needs. This had negative effects on both members of the caring dyad, ... ...

    Abstract Background: During the COVID-19 pandemic, reduced access to care services and fear of infection prompted families to increase home care for their older relatives with long-term care needs. This had negative effects on both members of the caring dyad, impacting their quality of life (QoL) and mental well-being. This study investigated the factors that influenced the mental well-being and QoL of 239 dyads, before and after the first pandemic wave in Italy.
    Methods: Data were collected through a survey on the use of health and social care services and interventions by older care recipients living in the community and their family caregivers. Factors associated with deterioration of mental well-being and QoL in older care recipients (mean age 86.1 years old) and their family caregivers after the pandemic were studied.
    Results: The importance attached by family caregivers to the skills and training of healthcare professionals was a protective factor against the deterioration in the well-being of older care recipients. Similarly, the importance associated by family caregivers to the help received from healthcare professionals was a protective factor for QoL. Financial hardship of older care recipients was a risk factor for deterioration in caregivers' mental well-being, while support from other family members was a protective factor for QoL.
    Conclusions: The presence of attentive healthcare professionals, a supportive family environment, and economic support can reduce the burden on both the caregiver and the older care recipient. These aspects need to be considered in any future emergency situation and when planning care services for community-dwelling older people.
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12030383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of Mindfulness Based Interventions in Adults and Older Adults Caregivers of Patients with Early Stage Alzheimer's Disease: A Randomized Pilot Study.

    Giulietti, Maria Velia / Fabbietti, Paolo / Spatuzzi, Roberta / Vespa, Anna

    Journal of Alzheimer's disease : JAD

    2024  Volume 97, Issue 4, Page(s) 1923–1930

    Abstract: Background: Many studies have highlighted the effect of training with mindfulness-based interventions (MBIs) on the psycho-physical rebalancing of patients suffering from various pathologies, and their families.: Objective: In this study, the effect ... ...

    Abstract Background: Many studies have highlighted the effect of training with mindfulness-based interventions (MBIs) on the psycho-physical rebalancing of patients suffering from various pathologies, and their families.
    Objective: In this study, the effect of a training with mindfulness-based stress reduction (MBSR) on quality of life and emotion regulation (depression) was verified in caregivers (CGs) of patients affected by Alzheimer's disease at early stage (AD-P).
    Methods: In this randomized controlled study, 22 CGs (age≥60 years) were treated with MBIs, in particular MBSR, and 22 CGs had no treatment. Tests (T0-T1 six months) included: SF 36-Quality of Life (QoL); Caregiver Burden Inventory (CBI); FACIT-Spiritual-Well-Being; Beck Depression Inventory (BDI); Everyday Cognition scales; and Mini-Mental State Examination (for AD-P).
    Results: Significant differences emerged between T0 and T1 for CGs with MBSR in the following dimensions: Depression-BDI (p > 0.001), Burden CBI-Total (0.001), CBI-Time dependent burden (p < 0.001), CBI-Developmental burden (p < 0.001), CBI-Physical burden (p < 0.001); and pain (p = 0.002) all decreased; while CBI-Social burden (p = 0.004), QoL-Health Role Limitation (p < 0.000), QoL-Role-Limitation-Emotional-Problem (p < 0.000), QoL-Energy-fatigue (p < 0.000), QoL-Emotional Well-Being (p < 0.001), QoL-Social Well Being (p = 0.010), and QoL-General Health (p = 0.004) increased. The control group of untreated CG showed a significant worsening in the dimensions of Physical functioning (p = 0.036) and pain (p = 0.047).
    Conclusions: AD-CGs treated with MBI reduced their burden and depression and experienced an improvement in all the dimensions of quality of life.
    MeSH term(s) Humans ; Aged ; Alzheimer Disease/therapy ; Alzheimer Disease/psychology ; Caregivers/psychology ; Quality of Life/psychology ; Pilot Projects ; Mindfulness ; Pain
    Language English
    Publishing date 2024-02-02
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-230284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comparing the cross-national impact of the COVID-19 pandemic on care received by community-dwelling older adults in 2020 and 2021: restoring formal home care versus polarizing informal care?

    Tur-Sinai, Aviad / Bentur, Netta / Fabbietti, Paolo / Lamura, Giovanni

    European journal of ageing

    2024  Volume 21, Issue 1, Page(s) 6

    Abstract: The COVID-19 pandemic has changed the supply of formal and informal home care to older adults in many countries across the world. This study aims to compare the initial picture of how the supply of formal and informal home care to older adults in ... ...

    Abstract The COVID-19 pandemic has changed the supply of formal and informal home care to older adults in many countries across the world. This study aims to compare the initial picture of how the supply of formal and informal home care to older adults in European countries and Israel changed during the first pandemic year (from mid-2020 to mid-2021) and to examine the changes that these countries made in the provision of adequate care to older adults. Using data from the two COVID-19 waves of SHARE, we show that the provision of formal home care services improved in the investigated period, as in 2021 the share of those who reported difficulties in receiving formal home care dropped significantly compared to the previous year. By contrast, informal care provision patterns experienced a growing polarization, with some countries continuing in reporting a strong support from this source, and others moving towards a remarkable reduction in the help coming from informal networks. These findings can serve as a basis for the development of evidence-based recommendations that can inform future care policies at the national level and to implement more sustainable models for older adults living in the community.
    Language English
    Publishing date 2024-01-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2190233-1
    ISSN 1613-9372
    ISSN 1613-9372
    DOI 10.1007/s10433-024-00800-6
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  4. Article ; Online: The Impact of Digital Coaching Intervention for Improving Healthy Ageing Dimensions among Older Adults during Their Transition from Work to Retirement.

    Santini, Sara / Fabbietti, Paolo / Galassi, Flavia / Merizzi, Alessandra / Kropf, Johannes / Hungerländer, Niklas / Stara, Vera

    International journal of environmental research and public health

    2023  Volume 20, Issue 5

    Abstract: Retirement is a critical step in older adults' lives, so it is important to motivate them to stay physically active, mentally healthy, and socially connected in the transition from work to retirement, including through digital health coaching programs. ... ...

    Abstract Retirement is a critical step in older adults' lives, so it is important to motivate them to stay physically active, mentally healthy, and socially connected in the transition from work to retirement, including through digital health coaching programs. This study aims to: evaluate the impact of a digital coaching intervention to enhance three healthy ageing dimensions, i.e., physical activity, mental well-being, and socialization of a group of adults near retirement; understand the users' experience; and identify the system strengths and weaknesses. This longitudinal mixed-methods study, carried out in 2021 in Italy and the Netherlands, enrolled 62 individuals. In the first 5 weeks of the trial, participants used a digital coach with the support of human coaches, and then they continued autonomously for another 5 weeks. The use of the digital coach improved the participants' physical activity, mental well-being and self-efficacy during the first period and only the physical activity in the second. An effective coaching system should be flexible and attractive. High levels of personalization remain the golden key to aligning the health program to the physical, cognitive and social status of the intended target, thus increasing the user-system interaction, usability, and acceptability, as well as enhancing adherence to the intervention.
    MeSH term(s) Humans ; Aged ; Healthy Aging ; Mentoring ; Retirement ; Mental Health ; Exercise
    Language English
    Publishing date 2023-02-24
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20054034
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  5. Article ; Online: Factors Worsening and Mitigating the Consequences of the COVID-19 Outbreak on the Overall Health of Informal Caregivers of Older People with Long-Term Care Needs Living in Germany and in Italy.

    Santini, Sara / Socci, Marco / Fabbietti, Paolo / Lamura, Giovanni / Teti, Andrea

    International journal of environmental research and public health

    2022  Volume 19, Issue 3

    Abstract: Population ageing and the higher prevalence of multimorbidity in later life are increasing the demand for Long-Term Care (LTC) worldwide; this has been exacerbated by the COVID-19 pandemic. As in Europe and beyond, the bulk of care for frail older people ...

    Abstract Population ageing and the higher prevalence of multimorbidity in later life are increasing the demand for Long-Term Care (LTC) worldwide; this has been exacerbated by the COVID-19 pandemic. As in Europe and beyond, the bulk of care for frail older people is carried out by informal caregivers. This study aimed at understanding the factors affecting the overall worsening health of informal caregivers of older people with LTC needs living in Germany and Italy during the outbreak. To this purpose, 319 informal caregivers (149 in Germany and 173 in Italy) were surveyed online in 2020-2021. A logistic regression analysis was performed by country, to obtain an adjusted estimate of the risk of worsening of caregivers' health. This risk increased by 42% for German caregivers compared to Italian ones, despite the former receiving more formal services. This may depend on different quality standards of LTC services and caregivers' expectations, and on differing policies concerning migrant care workers (MCWs) during the outbreak, who could not enter Germany and were "trapped" at care recipients' homes in Italy. Results call for in-home care reforms and policies guaranteeing more effective caregiver support, home care services and fairer working condition for MCWs in both countries.
    MeSH term(s) Aged ; COVID-19 ; Caregivers ; Germany/epidemiology ; Humans ; Italy/epidemiology ; Long-Term Care ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2022-02-01
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19031694
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  6. Article ; Online: Association between low values of mean arterial pressure and impaired cognitive performance in older patients with mild cognitive impairment: cross-sectional preliminary findings from the STRENGTH Project.

    Santillo, Elpidio / Balietti, Marta / Fabbietti, Paolo / Antolini, Maria Sole / Paoloni, Cristina / Piacenza, Francesco / Giuli, Cinzia

    Aging clinical and experimental research

    2024  Volume 36, Issue 1, Page(s) 9

    Abstract: Background: Uncontrolled blood pressure (BP) is a risk factor for Mild Cognitive Impairment (MCI) and dementia.: Aims: This study examined the relationship between BP and clinical/cognitive/neuropsychological aspects in MCI individuals.: Methods: ... ...

    Abstract Background: Uncontrolled blood pressure (BP) is a risk factor for Mild Cognitive Impairment (MCI) and dementia.
    Aims: This study examined the relationship between BP and clinical/cognitive/neuropsychological aspects in MCI individuals.
    Methods: MCI patients underwent clinical, functional, cognitive and metacognitive, as well as psychological assessments. Social network, lifestyle characteristics, and medication prescriptions were also evaluated. Each patient underwent BP measurements.
    Results: Lower values of systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were associated with poorer cognitive performance. Notably, MAP showed greater capability in detecting impairments in attention and visuospatial abilities compared to SBP and DBP.
    Discussion: These findings support the notion that in older individuals with MCI excessively low BP values, particularly MAP, might represent a risk and suggest that cerebral hypoperfusion may play a key role.
    Conclusions: Routine assessment of MAP could aid clinicians in adjusting antihypertensive treatment and closely monitoring cognitive function in MCI patients.
    MeSH term(s) Humans ; Aged ; Cross-Sectional Studies ; Arterial Pressure ; Cognitive Dysfunction/diagnosis ; Blood Pressure/physiology ; Cognition
    Language English
    Publishing date 2024-01-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-023-02668-5
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  7. Article: Using temperament and character dimensions (TCI) to analyze the personality profiles of adults and older adults with cancer managed in outpatient settings.

    Vespa, Anna / Giulietti, Maria Velia / Fabbietti, Paolo / Di Rosa, Mirko / Gattafoni, Pisana / Berardi, Rossana / Arnaldi, Giorgio / Balercia, Giancarlo / Spatuzzi, Roberta

    Frontiers in psychology

    2024  Volume 14, Page(s) 1289093

    Abstract: Introduction: This study aimed to investigate profiles of personality evaluated by temperament and character dimensions (TCI) in 638 adult and older adult patients (CP) who had recently been diagnosed with breast, colon, lung, and other kinds of cancer ( ...

    Abstract Introduction: This study aimed to investigate profiles of personality evaluated by temperament and character dimensions (TCI) in 638 adult and older adult patients (CP) who had recently been diagnosed with breast, colon, lung, and other kinds of cancer (female and male subjects were assessed). Tests: Temperament and Character Inventory (TCI). Statistical analysis: cluster K-means analysis for personality traits.
    Results: Two different personality profiles emerged: "Low self-determination and pessimism" (Profile 1) and "Self-determination and self-caring (medium)" (Profile 2). The following significant differences were observed in the TCI dimensions between the two profiles: Temperament-Novelty-Seeking (NS) (
    Conclusion: Personality screening allows a better understanding of the difficulties of the individual patient and the planning of targeted psychotherapeutic interventions that promote quality of life and good adaptation to the disease course.
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1289093
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  8. Article ; Online: Study of the effects of mindfulness training on quality of life of patients with Alzheimer's disease and their caregivers (Dyad Mindfulness Project).

    Vespa, Anna / Fabbietti, Paolo / Giulietti, Maria Velia

    Aging clinical and experimental research

    2021  Volume 34, Issue 1, Page(s) 65–71

    Abstract: Background: The training of mindfulness enhances the emotive and cognitive equilibrium and well-being in older adults. So some authors hypothesize it is an appropriate approach to cultivating these benefits and a good quality of life in Alzheimer's ... ...

    Abstract Background: The training of mindfulness enhances the emotive and cognitive equilibrium and well-being in older adults. So some authors hypothesize it is an appropriate approach to cultivating these benefits and a good quality of life in Alzheimer's patients (AD-P) at early stage and in their caregivers (Cg) (Dyad).
    Aim: Our main hypothesis is that AD-P and Cg who completed the program of Mindfulness-Based Interventions (MBIs) training would experience improvements in well-being and mood and cognitive performance (AD-P: attention and memory).
    Methods: The perspective randomized controlled will enroll the Dyad of 80 Alzheimer's patients (age ≥ 60) and 80 caregivers (age > 18) who will be randomly assigned to 6 months MBI training in groups and to control group study. All outcome will be analyzed before intervention (baseline), after follow-up 1 (at the end of treatment), after 6 months (follow-up 2) and after 1 year (follow-up 3) from the end of treatment.
    Discussion: AD-P-expected outcomes: (a) improvement of the quality of life (QoL-AD); (b) decrease of depression (BDI); (c) improvement of spiritual well-being (Facit SWB Index); (d) improvement of attention and good cognitive performance Rey Memory Test (MFIT); (e) decrease of neuropsychiatric symptoms. (NPI)-Cg-expected outcomes: (a) improvement of the quality of life (SF36); (b) decrease of the care burden (CBI); (c) decrease of depression (BDI); (d) improvement of self-awareness (FFMQ); (e) increase in spiritual-well-being (Facit SWB).
    Conclusions: This study could provide a clues on multidisciplinary interventions as secondary prevention of Alzheimer's dementia and on stress reduction in family caregivers.
    MeSH term(s) Adult ; Affect ; Aged ; Alzheimer Disease/therapy ; Caregivers ; Humans ; Middle Aged ; Mindfulness ; Quality of Life
    Language English
    Publishing date 2021-07-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-021-01907-x
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  9. Article ; Online: OGTT reproducibility in adults with impaired fasting glucose is nearly 65% with adoption of Italian SIBioC-SIPMeL recommendations.

    Testa, Roberto / Lo Cascio, Claudia / Fabbietti, Paolo / Bonfigli, Anna Rita

    Clinical chemistry and laboratory medicine

    2021  Volume 59, Issue 8, Page(s) e341–e343

    MeSH term(s) Adult ; Blood Glucose ; Diabetes Mellitus, Type 2 ; Fasting ; Glucose Intolerance/diagnosis ; Glucose Tolerance Test ; Humans ; Prediabetic State ; Reproducibility of Results
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2021-03-03
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2020-1518
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  10. Article ; Online: Dyadic associations between perceived social support and psychological well-being in caregivers and older care recipients.

    Ferraris, Giulia / Fisher, Oliver / Lamura, Giovanni / Fabbietti, Paolo / Gagliardi, Cristina / Hagedoorn, Mariët

    Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)

    2022  Volume 36, Issue 8, Page(s) 1397–1406

    Abstract: Caregiving can be burdensome for both family caregivers and older care recipients (i.e., adults 75 years or older with care needs). This study aimed to determine dyadic associations between caregivers' and care recipients' perceived social support from ... ...

    Abstract Caregiving can be burdensome for both family caregivers and older care recipients (i.e., adults 75 years or older with care needs). This study aimed to determine dyadic associations between caregivers' and care recipients' perceived social support from others (e.g., family and friends) and psychological well-being as a dyad. Caregivers and care recipients (
    MeSH term(s) Adult ; Humans ; Aged ; Caregivers/psychology ; Cross-Sectional Studies ; Social Support ; Italy
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 619328-6
    ISSN 1939-1293 ; 0893-3200
    ISSN (online) 1939-1293
    ISSN 0893-3200
    DOI 10.1037/fam0001009
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