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  1. Article: Parallel pathways: A chronicle of evolution in rectal and breast cancer surgery.

    Pesce, Antonio / Fabbri, Nicolò / Iovino, Diletta / Feo, Carlo Vittorio

    World journal of gastrointestinal oncology

    2024  Volume 16, Issue 4, Page(s) 1091–1096

    Abstract: In this editorial, we have analyzed the historical evolution of rectal and breast cancer surgery, focusing on the progressive reduction of demolitive approaches and the increasing use of more conservative strategies, accompanied by a growing emphasis on ... ...

    Abstract In this editorial, we have analyzed the historical evolution of rectal and breast cancer surgery, focusing on the progressive reduction of demolitive approaches and the increasing use of more conservative strategies, accompanied by a growing emphasis on perioperative treatments aimed at enhancing surgical outcomes. All of these changes have been made possible due to an increased awareness and understanding of oncological diseases and improved perioperative treatments.
    Language English
    Publishing date 2024-04-05
    Publishing country China
    Document type Editorial
    ZDB-ID 2573696-6
    ISSN 1948-5204
    ISSN 1948-5204
    DOI 10.4251/wjgo.v16.i4.1091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Should Fluorescent Cholangiography Become a Gold Standard During All Cholecystectomies?

    Pesce, Antonio / Fabbri, Nicolò / Feo, Carlo Vittorio

    Journal of the American College of Surgeons

    2023  Volume 237, Issue 1, Page(s) 169

    MeSH term(s) Humans ; Cholangiography ; Cholecystectomy ; Coloring Agents ; Cholecystectomy, Laparoscopic
    Chemical Substances Coloring Agents
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1097/XCS.0000000000000696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Vascular injury during laparoscopic cholecystectomy: An often-overlooked complication.

    Pesce, Antonio / Fabbri, Nicolò / Feo, Carlo Vittorio

    World journal of gastrointestinal surgery

    2023  Volume 15, Issue 3, Page(s) 338–345

    Abstract: Laparoscopic cholecystectomy is one of the most frequently performed procedures in gastrointestinal surgery worldwide. Bleeding complications due to vascular injuries represent an important cause of morbidity and mortality, especially when facing major ... ...

    Abstract Laparoscopic cholecystectomy is one of the most frequently performed procedures in gastrointestinal surgery worldwide. Bleeding complications due to vascular injuries represent an important cause of morbidity and mortality, especially when facing major bleeding during laparoscopy, where bleeding control can be technically challenging in inexperienced hands. Interestingly, the reported incidence rate of conversion to open surgery due to vascular lesions is approximately 0%-1.9%, with a mortality rate of approximately 0.02%. The primary aim of this article was to perform an up-to-date overview regarding the incidence and surgical management of vascular injuries during laparoscopic cholecystectomy according to the available scientific evidence.
    Language English
    Publishing date 2023-03-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573700-4
    ISSN 1948-9366
    ISSN 1948-9366
    DOI 10.4240/wjgs.v15.i3.338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of Modified Frailty Index on Readmissions Following Surgery for NSCLC.

    Tamburini, Nicola / Dolcetti, Francesco / Fabbri, Nicolò / Azzolina, Danila / Greco, Salvatore / Maniscalco, Pio / Dolci, Giampiero

    The Thoracic and cardiovascular surgeon

    2024  

    Abstract: Background:  Analyzing the risk factors that predict readmissions can potentially lead to more individualized patient care. The 11-factor modified frailty index is a valuable tool for predicting postoperative outcomes following surgery. The objective of ...

    Abstract Background:  Analyzing the risk factors that predict readmissions can potentially lead to more individualized patient care. The 11-factor modified frailty index is a valuable tool for predicting postoperative outcomes following surgery. The objective of this study is to determine whether the frailty index can effectively predict readmissions within 90 days after lung resection surgery in cancer patients within a single health care institution.
    Methods:  Patients who underwent elective pulmonary resection for nonsmall cell lung cancer (NSCLC) between January 2012 and December 2020 were selected from the hospital's database. Patients who were readmitted after surgery were compared to those who were not, based on their data. Propensity score matching was employed to enhance sample homogeneity, and further analyses were conducted on this newly balanced sample.
    Results:  A total of 439 patients, with an age range of 68 to 77 and a mean age of 72, were identified. Among them, 55 patients (12.5%) experienced unplanned readmissions within 90 days, with an average hospital stay of 29.4 days. Respiratory failure, pneumonia, and cardiac issues accounted for approximately 67% of these readmissions. After propensity score matching, it was evident that frail patients had a significantly higher risk of readmission. Additionally, frail patients had a higher incidence of postoperative complications and exhibited poorer survival outcomes with statistical significance.
    Conclusion:  The 11-item modified frailty index is a reliable predictor of readmissions following pulmonary resection in NSCLC patients. Furthermore, it is significantly associated with both survival and postoperative complications.
    Language English
    Publishing date 2024-04-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/a-2287-2341
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  5. Article ; Online: Letter to the editor: A point of view on telemedicine in colorectal surgery.

    Fabbri, Nicolò / Pesce, Antonio / Greco, Salvatore / Feo, Carlo Vittorio

    Surgery

    2023  Volume 174, Issue 4, Page(s) 1097–1098

    MeSH term(s) Humans ; Colorectal Surgery ; COVID-19 ; SARS-CoV-2 ; Telemedicine ; Digestive System Surgical Procedures
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2023.01.014
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  6. Article: Diet and nutrition against inflammatory bowel disease: Trick or treat(ment)?

    Greco, Salvatore / Bonsi, Beatrice / Fabbri, Nicolò

    World journal of experimental medicine

    2022  Volume 12, Issue 5, Page(s) 104–107

    Abstract: Even if the relationships between nutrition and inflammatory bowel disease (IBD) remain underexplored, the current literature is providing, day by day, much more evidence on the effects of various diets in both prevention and treatment of such illnesses. ...

    Abstract Even if the relationships between nutrition and inflammatory bowel disease (IBD) remain underexplored, the current literature is providing, day by day, much more evidence on the effects of various diets in both prevention and treatment of such illnesses. Wrong dietary habits, together with other environmental factors such as pollution, breastfeeding, smoke, and/or antibiotics, are among the theoretical pathogenetic causes of IBD, whose multifactorial aetiology has been already confirmed. While some of these risk factors are potentially reversible, some others cannot be avoided, and efficient treatments become necessary to prevent IBD spread or recurrence. Furthermore, the drugs currently available for treatment of such disease provide low-to-no effect against the symptoms, making the illnesses still strongly disabling. Whether nutrition and specific diets will prove to effectively interrupt the course of IBD has still to be clarified and, in this sense, further research concerning the applications of such dietary interventions is still needed.
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2764849-7
    ISSN 2220-315X
    ISSN 2220-315X
    DOI 10.5493/wjem.v12.i5.104
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  7. Article ; Online: Like a Rolling (Gall)Stone: Optimal Treatment of Gallstone Obstruction of the Sigmoid Colon.

    Pesce, Antonio / Lauro, Augusto / Gonella Pacchiotti, Costanza / D'Andrea, Vito / Fabbri, Nicolò / Bertasi, Mario / Feo, Carlo Vittorio

    Digestive diseases and sciences

    2024  

    Abstract: Background: Sigmoid gallstone ileus is a rare complication of cholelithiasis, accounting for 1-4% of all cases of large-bowel obstruction. This is a highly morbid, and often fatal, condition due to its challenging diagnosis and late presentation.: ... ...

    Abstract Background: Sigmoid gallstone ileus is a rare complication of cholelithiasis, accounting for 1-4% of all cases of large-bowel obstruction. This is a highly morbid, and often fatal, condition due to its challenging diagnosis and late presentation.
    Case presentation: We report a case of a 90-year-old woman admitted to Emergency Department with abdominal pain and large-bowel obstruction due to a 6 cm gallstone lodged in a diverticulum of the proximal sigmoid colon as a consequence of a cholecysto-colonic fistula. Colonoscopy was deferred due to gallstone size carrying a high possibility of failure. The patient underwent urgent laparotomy with gallstone removal via colotomy. The cholecystocolonic fistula was left untreated. The post-operative course was uneventful; the patient was discharged on 6th post-operative day.
    Conclusion: A multidisciplinary discussion between endoscopists and surgeons is often needed to choose the best therapeutic option, especially in high-risk patients.
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-024-08328-6
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  8. Article: Update on Classic and Novel Approaches in Metastatic Triple-Negative Breast Cancer Treatment: A Comprehensive Review.

    Greco, Salvatore / Fabbri, Nicolò / Spaggiari, Riccardo / De Giorgi, Alfredo / Fabbian, Fabio / Giovine, Antonio

    Biomedicines

    2023  Volume 11, Issue 6

    Abstract: Triple-negative breast cancer (TNBC) accounts for almost 15% of all diagnosed breast cancers and often presents high rates of relapses and metastases, with generally poor prognosis despite multiple lines of treatment. Immunotherapy has radically changed ... ...

    Abstract Triple-negative breast cancer (TNBC) accounts for almost 15% of all diagnosed breast cancers and often presents high rates of relapses and metastases, with generally poor prognosis despite multiple lines of treatment. Immunotherapy has radically changed the approach of clinicians towards TNBC in the last two to three years, even if targeted and specific therapeutic options are still missing; this unmet need is further justified by the extreme molecular and clinical heterogeneity of this subtype of breast cancer and by the weak response to both single-agent and combined therapies. In March 2023, the National Comprehensive Cancer Network (NCCN), the main association of cancer centers in the United States, released the last clinical practice guidelines, with an update on classic and novel approaches in the field of breast cancer. The purpose of this comprehensive review is to summarize the latest findings in the setting of metastatic TNBC treatment, focusing on each category of drugs approved by the Food and Drug Administration (FDA) and included in the NCCN guidelines. We also introduce part of the latest published studies, which have reported new and promising molecules able to specifically target some of the biomarkers involved in TNBC pathogenesis. We searched the PubMed and Scopus databases for free full texts reported in the literature of the last 5 years, using the words "triple-negative breast cancer" or "TNBC" or "basal-like". The articles were analyzed by the authors independently and double-blindly, and a total of 114 articles were included in the review.
    Language English
    Publishing date 2023-06-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11061772
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  9. Article ; Online: Incisional Hernia After Laparoscopic Right Colectomy for Colorectal Cancer: A Prospective Study with Retrospective Control on Intracorporeal Versus Extracorporeal Anastomosis.

    Pesce, Antonio / Petrarulo, Francesca / Fabbri, Nicolò / Portinari, Mattia / Feo, Carlo Vittorio

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2023  Volume 34, Issue 2, Page(s) 113–119

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Incisional Hernia/epidemiology ; Incisional Hernia/etiology ; Incisional Hernia/surgery ; Retrospective Studies ; Prospective Studies ; Cohort Studies ; Colectomy/adverse effects ; Colectomy/methods ; Colonic Neoplasms/surgery ; Postoperative Complications/etiology ; Anastomosis, Surgical/methods ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Treatment Outcome
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2023.0453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Impact of Modified Frailty Index on Readmissions Following Surgery for NSCLC

    Tamburini, Nicola / Dolcetti, Francesco / Fabbri, Nicolò / Azzolina, Danila / Greco, Salvatore / Maniscalco, Pio / Dolci, Giampiero

    The Thoracic and Cardiovascular Surgeon

    2024  

    Abstract: Background: Analyzing the risk factors that predict readmissions can potentially lead to more individualized patient care. The 11-factor modified frailty index is a valuable tool for predicting postoperative outcomes following surgery. The objective of ... ...

    Abstract Background: Analyzing the risk factors that predict readmissions can potentially lead to more individualized patient care. The 11-factor modified frailty index is a valuable tool for predicting postoperative outcomes following surgery. The objective of this study is to determine whether the frailty index can effectively predict readmissions within 90 days after lung resection surgery in cancer patients within a single health care institution.
    Methods: Patients who underwent elective pulmonary resection for nonsmall cell lung cancer (NSCLC) between January 2012 and December 2020 were selected from the hospital's database. Patients who were readmitted after surgery were compared to those who were not, based on their data. Propensity score matching was employed to enhance sample homogeneity, and further analyses were conducted on this newly balanced sample.
    Results: A total of 439 patients, with an age range of 68 to 77 and a mean age of 72, were identified. Among them, 55 patients (12.5%) experienced unplanned readmissions within 90 days, with an average hospital stay of 29.4 days. Respiratory failure, pneumonia, and cardiac issues accounted for approximately 67% of these readmissions. After propensity score matching, it was evident that frail patients had a significantly higher risk of readmission. Additionally, frail patients had a higher incidence of postoperative complications and exhibited poorer survival outcomes with statistical significance.
    Conclusion: The 11-item modified frailty index is a reliable predictor of readmissions following pulmonary resection in NSCLC patients. Furthermore, it is significantly associated with both survival and postoperative complications.
    Keywords frailty ; thoracic surgery ; risk stratification ; surgical outcomes ; risk models
    Language English
    Publishing date 2024-03-13
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/a-2287-2341
    Database Thieme publisher's database

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