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  1. Article ; Online: Cerebral autoregulation derived blood pressure targets in elective neurosurgery.

    Beqiri, Erta / García-Orellana, Marta / Politi, Anna / Zeiler, Frederick A / Placek, Michal M / Fàbregas, Neus / Tas, Jeanette / De Sloovere, Veerle / Czosnyka, Marek / Aries, Marcel / Valero, Ricard / de Riva, Nicolás / Smielewski, Peter

    Journal of clinical monitoring and computing

    2024  

    Abstract: Poor postoperative outcomes may be associated with cerebral ischaemia or hyperaemia, caused by episodes of arterial blood pressure (ABP) being outside the range of cerebral autoregulation (CA). Monitoring CA using COx (correlation between slow changes in ...

    Abstract Poor postoperative outcomes may be associated with cerebral ischaemia or hyperaemia, caused by episodes of arterial blood pressure (ABP) being outside the range of cerebral autoregulation (CA). Monitoring CA using COx (correlation between slow changes in mean ABP and regional cerebral O
    Language English
    Publishing date 2024-01-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-023-01115-0
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    Zs.A 2054: Show issues Location:
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  2. Article ; Online: Postoperative stroke: The picture is out of focus.

    Jacas, Adriana / Magaldi, Marta / Fàbregas, Neus / Valero, Ricard

    European journal of anaesthesiology

    2018  Volume 35, Issue 11, Page(s) 896–898

    MeSH term(s) Aged ; Aged, 80 and over ; Brain Ischemia/epidemiology ; Brain Ischemia/etiology ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/physiopathology ; Retrospective Studies ; Risk Factors ; Stroke/epidemiology ; Stroke/etiology ; Time Factors
    Language English
    Publishing date 2018-10-02
    Publishing country England
    Document type Letter
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000000828
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  3. Article ; Online: Placement in the prone position predisposes patients to a near volume-response state. A plethysmographic comparison of two prone positions using the Pleth Variability index.

    Maldonado, Felipe / Fábregas, Neus / Ortega, Roger / Carrero, Enrique / Valero, Ricard

    Journal of clinical anesthesia

    2019  Volume 58, Page(s) 79–80

    MeSH term(s) Cohort Studies ; Humans ; Patient Positioning ; Plethysmography/methods ; Prone Position/physiology ; Prospective Studies ; Supine Position/physiology
    Language English
    Publishing date 2019-05-18
    Publishing country United States
    Document type Comparative Study ; Letter ; Observational Study
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2019.05.015
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    Zs.A 2622: Show issues Location:
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  4. Article ; Online: Craniotomy in sitting position: anesthesiology management.

    Gracia, Isabel / Fabregas, Neus

    Current opinion in anaesthesiology

    2014  Volume 27, Issue 5, Page(s) 474–483

    Abstract: Purpose of review: Sitting position to surgically approach posterior fossa disorder continues to be the first choice for some neurosurgical teams. We underwent a literature research for recent published studies involving neurosurgical patients operated ... ...

    Abstract Purpose of review: Sitting position to surgically approach posterior fossa disorder continues to be the first choice for some neurosurgical teams. We underwent a literature research for recent published studies involving neurosurgical patients operated on in this position. Preoperative evaluation, anesthetic technique, intraoperative monitoring, detection and treatment of venous or arterial air embolism episodes, and all the reported complications were recorded.
    Recent findings: A modified semisitting (lounging) position aiming to create a positive pressure in the transverse and sigmoid sinuses, with lower head and higher legs positioned above the top of the head, decreases the incidence and severity of venous air embolism. Hyperventilation, compromising cerebral blood flow, has to be avoided during a sitting position. Precordial Doppler or transesophageal echocardiography monitoring improves the detection of small venous air embolism enabling its early treatment and diminishing its consequences. Patients with known patent foramen ovale can be operated on in a sitting position, under strict protocol, with few reported clinical venous air embolism and no paradoxical air embolism.
    Summary: Sitting position for neurosurgical procedures may be a well tolerated approach for the patient if neurosurgeons and neuroanesthesiologists undergo a strict team protocol, including all necessary monitoring and meticulously followed.
    MeSH term(s) Brain Diseases/surgery ; Craniotomy/methods ; Embolism, Air/prevention & control ; Humans ; Monitoring, Intraoperative/methods ; Neurosurgical Procedures/methods ; Patient Positioning/methods ; Posture
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000000104
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    Zs.A 2564: Show issues Location:
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  5. Article ; Online: Increased detection of thromboembolic events in neurosurgical patients after updating the perioperative thromboprophylaxis protocol.

    Chanzá, Mireia / Hurtado, Paola / Enseñat, Joaquim / Fàbregas, Neus / Valero, Ricard

    Neurocirugia (English Edition)

    2018  Volume 30, Issue 2, Page(s) 101–102

    Title translation Aumento de la detección de eventos tromboembólicos en pacientes neuroquirúrgicos tras la actualización del protocolo de tromboprofilaxis perioperatoria.
    MeSH term(s) Anticoagulants ; Consensus ; Fibrinolytic Agents ; Humans ; Neurosurgery ; Platelet Aggregation Inhibitors ; Venous Thromboembolism
    Chemical Substances Anticoagulants ; Fibrinolytic Agents ; Platelet Aggregation Inhibitors
    Language Spanish
    Publishing date 2018-12-11
    Document type Letter ; Comment
    ISSN 2529-8496
    ISSN (online) 2529-8496
    DOI 10.1016/j.neucir.2018.11.002
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  6. Article ; Online: Bilateral Bispectral Index Monitoring Performance in the Detection of Seizures in Nonanesthetized Epileptic Patients: An Observational Study.

    Fàbregas, Neus / Valencia, Jose F / Belda, Isabel / Tercero, Ana / Hervias, Adriana / Villafuerte, Santiago / Gambús, Pedro L / Carreño, Mar / Valero, Ricard

    Journal of neurosurgical anesthesiology

    2021  Volume 34, Issue 4, Page(s) 419–423

    Abstract: Background: The aim of this observational study was to determine whether bilateral bispectral index (BIS) monitoring can detect seizures in epileptic patients.: Methods: Four-channel frontal BIS monitoring and standard 40-channel ... ...

    Abstract Background: The aim of this observational study was to determine whether bilateral bispectral index (BIS) monitoring can detect seizures in epileptic patients.
    Methods: Four-channel frontal BIS monitoring and standard 40-channel electroencephalography monitoring were conducted in epileptic patients undergoing evaluation for epilepsy surgery. The BIS numerical value, signal quality index, electromyography, suppression ratio, and color density spectral array were continuously recorded. In patients with electroencephalography-confirmed seizures, the mean value and trend (slope of linear regression) of bilateral BIS monitor parameters were analyzed from 1 minute before to 1 minute after seizure onset.
    Results: Of 48 patients included in the study, 21 (43.8%) had at least 1 seizure. BIS numerical value was not able to detect focal or focal to bilateral tonic-clonic seizures. Considering all seizures, the only significant differences between recordings 1 minute before and 1 minute after seizure onset were a decrease in the signal quality index slope from 1 hemisphere (0.039±0.297 vs. -0.085±0.321, respectively; P =0.029) and in the mean signal quality index recorded from both hemispheres (left hemisphere: 65.775±30.599 vs. 61.032±26.285; P =0.016 and right hemisphere: 63.244±31.985 vs. 59.837±27.360; 0.029); these differences were not maintained after Hochberg adjustment for multiple comparisons. In seizures occurring during sleep, there was a change in the electromyography slope of 1 hemisphere before and after seizure onset (-0.141±0.176 vs. 0.162±0.140, respectively; P =0.038). There were variable responses in BIS parameters in the 3 patients who developed focal nonconvulsive seizure clusters.
    Conclusion: Bilateral BIS monitoring was not able to detect the occurrence of seizures in epileptic patients.
    MeSH term(s) Consciousness Monitors ; Electroencephalography ; Epilepsy/diagnosis ; Humans ; Monitoring, Physiologic ; Seizures/diagnosis
    Language English
    Publishing date 2021-06-07
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1018119-2
    ISSN 1537-1921 ; 0898-4921
    ISSN (online) 1537-1921
    ISSN 0898-4921
    DOI 10.1097/ANA.0000000000000780
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    Zs.A 2656: Show issues Location:
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  7. Article ; Online: Use of second generation supraglottic airway device for endovascular treatment of unruptured intracranial aneurysms: a retrospective cohort.

    Hurtado, Paola / Garcia-Orellana, Marta / Amaro, Sergi / Carrero, Enrique / Zarco, Federico / Lopez, Anna / Fabregas, Neus / Valero, Ricard

    Brazilian journal of anesthesiology (Elsevier)

    2021  Volume 71, Issue 4, Page(s) 408–412

    Abstract: Background: We aimed to assess the feasibility of using supraglottic devices as an alternative to orotracheal intubation for airway management during anesthesia for endovascular treatment of unruptured intracranial aneurisms in our department over a ... ...

    Abstract Background: We aimed to assess the feasibility of using supraglottic devices as an alternative to orotracheal intubation for airway management during anesthesia for endovascular treatment of unruptured intracranial aneurisms in our department over a nine-year period.
    Methods: Retrospective single center analysis of cases (2010-2018). Primary outcomes: airway management (supraglottic device repositioning, need for switch to orotracheal intubation, airway complications).
    Secondary outcomes: aneurysm complexity, history of subarachnoid hemorrhage, hemodynamic monitoring, and perioperative complications.
    Results: We included 187 patients in two groups: supraglottic device 130 (69.5%) and orotracheal intubation 57 (30.5%). No adverse incidents were recorded in 97% of the cases. Three supraglottic device patients required supraglottic device repositioning and 1 supraglottic device patient required orotracheal intubation due to inadequate ventilation. Three orotracheal intubation patients had a bronchospasm or laryngospasm during awakening. Forty-five patients (24.1%) had complex aneurysms or a history of subarachnoid hemorrhage. Thirty-three of them (73.3%) required orotracheal intubation compared to 24 of the 142 (16.9%) with non-complex aneurysms. Two patients in each group died during early postoperative recovery. Two in each group also had intraoperative bleeding. A post-hoc analysis showed that orotracheal intubation was used in 55 patients (44%) in 2010 through 2014 and 2 (3.2%) in 2015 through 2018, parallel to a trend toward less invasive blood pressure monitoring from the earlier to the later period from 34 (27.2%) cases to 5 (8.2%).
    Conclusion: Supraglottic device, like other less invasiveness protocols, can be considered a feasible alternative airway management approach in selected patients proposed for endovascular treatment of unruptured intracranial aneurisms.
    MeSH term(s) Airway Management ; Anesthesiology ; Humans ; Intracranial Aneurysm/surgery ; Intubation, Intratracheal ; Retrospective Studies
    Language English
    Publishing date 2021-04-26
    Publishing country Brazil
    Document type Journal Article
    ISSN 2352-2291
    ISSN (online) 2352-2291
    DOI 10.1016/j.bjane.2021.04.008
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  8. Article: Respuesta del autor al artículo «Sobre las complicaciones de las biopsias cerebrales», de J. Ibáñez et al.

    Gonzàlez, Josep / Gracia, Isabel / Valero, Ricard / Fàbregas, Neus

    Neurocirugia (Asturias, Spain)

    2016  Volume 27, Issue 1, Page(s) 39–40

    Title translation Author's response to article «The complications of brain biopsies», by J. Ibáñez et al.
    MeSH term(s) Brain/pathology ; Female ; Humans ; Male ; Postoperative Care ; Postoperative Complications/diagnosis ; Postoperative Complications/therapy
    Language Spanish
    Publishing date 2016-01
    Publishing country Spain
    Document type Comment ; Letter
    ZDB-ID 2151282-6
    ISSN 1130-1473
    ISSN 1130-1473
    DOI 10.1016/j.neucir.2015.10.001
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  9. Article ; Online: Anaesthesia and endovascular therapy in patients with acute ischaemic stroke.

    Valencia, Lucía / Iturri, Fernando / Fàbregas, Neus / Ingelmo, Ildefonso / Álvarez-Escudero, Julián

    European journal of anaesthesiology

    2019  Volume 36, Issue 4, Page(s) 305–306

    MeSH term(s) Anesthesia ; Anesthetics ; Brain Ischemia ; Endovascular Procedures ; Humans ; Stroke ; Surveys and Questionnaires
    Chemical Substances Anesthetics
    Language English
    Publishing date 2019-02-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000000961
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  10. Article ; Online: Thermoregulation and neuroanesthesia.

    Carrero, Enrique J / Fàbregas, Neus

    Saudi journal of anaesthesia

    2012  Volume 6, Issue 1, Page(s) 5–7

    Language English
    Publishing date 2012-02-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 2562174-9
    ISSN 0975-3125 ; 0975-3125
    ISSN (online) 0975-3125
    ISSN 0975-3125
    DOI 10.4103/1658-354X.93043
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