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  1. Article: Venous Thromboembolism Management throughout the COVID-19 Era: Addressing Acute and Long-Term Challenges.

    Wu, Maddalena Alessandra / Taino, Alba / Facchinetti, Pietro / Rossi, Valentina / Ruggiero, Diego / Berra, Silvia / Blanda, Giulia / Flor, Nicola / Cogliati, Chiara / Colombo, Riccardo

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Low-molecular-weight heparin for the prevention of clinical worsening in severe non-critically ill COVID-19 patients: a joint analysis of two randomized controlled trials.

    Wu, Maddalena Alessandra / Del GIovane, Cinzia / Colombo, Riccardo / Dolci, Giovanni / Arquati, Massimo / Vicini, Roberto / Russo, Umberto / Ruggiero, Diego / Coluccio, Valeria / Taino, Alba / Franceschini, Erica / Facchinetti, Pietro / Mighali, Pasquale / Trombetta, Lucia / Tonelli, Francesca / Gabiati, Claudia / Cogliati, Chiara / D'Amico, Roberto / Marietta, Marco

    Internal and emergency medicine

    2023  Volume 19, Issue 1, Page(s) 71–79

    Abstract: Coronavirus disease 2019 (COVID-19) carries a high risk of vascular thrombosis. However, whether a specific anticoagulation intensity strategy may prevent clinical worsening in severe COVID-19 patients is still debated. We conducted a joint analysis of ... ...

    Abstract Coronavirus disease 2019 (COVID-19) carries a high risk of vascular thrombosis. However, whether a specific anticoagulation intensity strategy may prevent clinical worsening in severe COVID-19 patients is still debated. We conducted a joint analysis of two randomized controlled trials, COVID-19 HD (NCT044082359) and EMOS-COVID (NCT04646655), to assess the efficacy and safety of two anticoagulant regimens in hospitalized severe COVID-19 patients. Subjects with COVID-19-associated respiratory compromise and/or coagulopathy were randomly assigned to low (4000 IU qd) or high (70 IU Kg
    MeSH term(s) Humans ; Anticoagulants/adverse effects ; COVID-19/complications ; Enoxaparin/adverse effects ; Hemorrhage/chemically induced ; Heparin, Low-Molecular-Weight/adverse effects ; Hospital Mortality ; Randomized Controlled Trials as Topic
    Chemical Substances Anticoagulants ; Enoxaparin ; Heparin, Low-Molecular-Weight
    Language English
    Publishing date 2023-10-04
    Publishing country Italy
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-023-03439-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical-radiological correlations in COVID-19-related venous thromboembolism: Preliminary results from a multidisciplinary study.

    Wu, Maddalena Alessandra / Colombo, Riccardo / Arquati, Massimo / Ippolito, Sonia / Taino, Alba / Ruggiero, Diego / Tonelli, Francesca / Trombetta, Lucia / Facchinetti, Pietro / Glielmo, Pierluigi / Cogliati, Chiara / Flor, Nicola

    International journal of clinical practice

    2021  Volume 75, Issue 9, Page(s) e14370

    Abstract: Introduction: Among the multiple complex pathophysiological mechanisms underlying COVID-19 pneumonia, immunothrombosis has been shown to play a key role. One of the most dangerous consequences of the prothrombotic imbalance is the increased incidence of ...

    Abstract Introduction: Among the multiple complex pathophysiological mechanisms underlying COVID-19 pneumonia, immunothrombosis has been shown to play a key role. One of the most dangerous consequences of the prothrombotic imbalance is the increased incidence of micro- and macrothrombotic phenomena, especially deep vein thrombosis (DVT) and pulmonary embolism (PE).
    Methods: We investigated the correlation between radiological and clinical-biochemical characteristics in a cohort of hospitalised COVID-19 patients.
    Results: PE was confirmed in 14/61 (23%) patients, five (35.7%) had DVT. The radiographic findings, quantified by Qanadli score calculated on CT angiography, correlated with the clinical score and biochemical markers. The ratio between the right and left ventricle diameter measured at CT angiography correlated with the length of hospital stay.
    Conclusion: In our cohort radiological parameters showed a significant correlation with clinical prognostic indices and scores, thus suggesting that a multidisciplinary approach is advisable in the evaluation of PE in COVID-19 patients.
    MeSH term(s) COVID-19 ; Computed Tomography Angiography ; Humans ; Pulmonary Embolism/diagnostic imaging ; Risk Factors ; SARS-CoV-2 ; Venous Thromboembolism/diagnostic imaging ; Venous Thromboembolism/etiology
    Language English
    Publishing date 2021-05-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 1386246-7
    ISSN 1742-1241 ; 1368-5031
    ISSN (online) 1742-1241
    ISSN 1368-5031
    DOI 10.1111/ijcp.14370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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