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  1. Article ; Online: Totally endoscopic cartilage tympanoplasty: a hierarchical task analysis.

    Fahy, R / Corbett, M / Crotty, T / Chadwick, L / Keogh, I

    The Journal of laryngology and otology

    2022  Volume 137, Issue 12, Page(s) 1326–1333

    Abstract: Background: Totally endoscopic ear surgery is a novel method of conducting otological surgery. Hierarchical task analysis and the systematic human error reduction and prediction approach ('SHERPA') are valuable tools that can effectively deconstruct the ...

    Abstract Background: Totally endoscopic ear surgery is a novel method of conducting otological surgery. Hierarchical task analysis and the systematic human error reduction and prediction approach ('SHERPA') are valuable tools that can effectively deconstruct the technical and non-technical skills required to successfully complete a surgical procedure.
    Methods: Twenty-five endoscopic tragal cartilage tympanoplasties were observed, to identify the tasks and subtasks required for completion of totally endoscopic tragal cartilage tympanoplasty. The systematic human error reduction and prediction approach was used to identify the potential risks and methods, to reduce or remediate these risks.
    Results: A hierarchical task analysis was performed, identifying 8 tasks and 50 subtasks for a safe approach to completing totally endoscopic tragal cartilage tympanoplasty. A risk score for each subtask was calculated to produce a systematic human error reduction and prediction approach and to highlight potential errors.
    Conclusion: This hierarchical task analysis allowed for quick reference to a correct method of endoscopic tympanoplasty. The systematic human error reduction and prediction approach was employed to reduce the risks associated with undergoing endoscopic tympanoplasty, to improve patient safety.
    MeSH term(s) Humans ; Tympanoplasty/methods ; Treatment Outcome ; Retrospective Studies ; Cartilage ; Endoscopy/methods
    Language English
    Publishing date 2022-09-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215122001992
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  2. Article ; Online: Improving peri-operative psychosocial interventions for children with autism spectrum disorder undergoing ENT procedures.

    Fahy, R / Corbett, M / Keogh, I

    The Journal of laryngology and otology

    2020  , Page(s) 1–7

    Abstract: Objectives: Children with autism spectrum disorder face a broad range of communication and sensory challenges. Many of these children also have chronic ENT issues. This study aims to better understand these challenges and improve our services for ... ...

    Abstract Objectives: Children with autism spectrum disorder face a broad range of communication and sensory challenges. Many of these children also have chronic ENT issues. This study aims to better understand these challenges and improve our services for children with autism spectrum disorder.
    Methods: Questionnaires and semi-structured interviews were carried out with parents of children with autism spectrum disorder.
    Results: Thirty-four individuals participated, comprising 9 caregivers and 25 staff members. All parents recognised their critical roles in understanding their children's special needs and sensitivities. Parents and staff stressed the importance of a partnership role that inquired about unique needs, leading to environmental modifications for individual children.
    Conclusion: The importance of listening to and involving caregivers is a fundamental tenet; parents must be recognised as the experts. Uncertainty must be kept to a minimum, with clear communication in a structured, low-arousal environment for these children. We have listened to parents and staff, and developed a social story.
    Language English
    Publishing date 2020-09-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215120002029
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  3. Article: Factors Affecting Frenotomy: A Single Institution's Experience with Ankyloglossia.

    Kelly, Á / Corbett, M / McGlynn, B / Fahy, R / Choo, M

    Irish medical journal

    2022  Volume 115, Issue No.10, Page(s) 693

    MeSH term(s) Humans ; Infant ; Female ; Ankyloglossia/surgery ; Breast Feeding ; Treatment Outcome
    Language English
    Publishing date 2022-12-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
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  4. Article: National Survey of Non-Consultant Hospital Doctors' Awareness & Attitudes towards Smoking Cessation Interventions in the Outpatient Setting.

    Power Foley, M / Fahy, R / Khan, T / Gosi, G / McGonagle, M P / Simon Cross, K

    Irish medical journal

    2023  Volume 116, Issue 5, Page(s) 778

    MeSH term(s) Humans ; Smoking Cessation ; Outpatients ; Hospitals ; Attitude of Health Personnel ; Surveys and Questionnaires
    Language English
    Publishing date 2023-05-18
    Publishing country Ireland
    Document type Letter
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
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  5. Article ; Online: Dr Sr Mary Glowrey JMJ, MB BS 1910, MD 1919: Australia's second saint?

    Healy, Jacqueline / Fahy, Robyn

    The Medical journal of Australia

    2015  Volume 203, Issue 11, Page(s) 450–451

    MeSH term(s) Australia ; Catholicism/history ; Delivery of Health Care/history ; History, 19th Century ; History, 20th Century ; Humans ; Medical Missions/history ; Physicians, Women/history
    Language English
    Publishing date 2015-12-10
    Publishing country Australia
    Document type Biography ; Historical Article ; Portrait
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja15.01028
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  6. Article ; Online: Digitally Enabled Transitional Care Management in Oncology.

    Daly, Bobby / Cracchiolo, Jennifer / Holland, Jessie / Ebstein, AnnMarie Mazzella / Flynn, Jessica / Duck, Elaine / Moy, Morgan / Walters, Chasity B / Giacomazzo, Lisa / Huang, Jennie / Fahy, Rosanna / Bernal, Camila / Ackerman, Jill / Salvaggio, Rori / Begue, Aaron / Raj, Nitya / Kuperman, Gilad / Mao, Jun J / Panageas, Katherine

    JCO oncology practice

    2024  Volume 20, Issue 5, Page(s) 657–665

    Abstract: Purpose: Improving care transitions for patients with cancer discharged from the hospital is considered an important component of quality care. Digital monitoring has the potential to better the delivery of transitional care through improved patient- ... ...

    Abstract Purpose: Improving care transitions for patients with cancer discharged from the hospital is considered an important component of quality care. Digital monitoring has the potential to better the delivery of transitional care through improved patient-provider communication and enhanced symptom management. However, remote patient monitoring (RPM) interventions have not been widely implemented for oncology patients after discharge, an innovative setting in which to apply this technology.
    Methods: We implemented a RPM intervention which identifies medical oncology patients at discharge, monitors their symptoms for 10 days, and intervenes as necessary to manage symptoms. We evaluated the feasibility (>50% patient engagement with symptom assessment), appropriateness (symptom alerts), and acceptability (net promoter score >0.7) of the intervention and the initial effect on acute care visits and return on investment.
    Results: During the study period, January 1, 2021, to December 31, 2022, we evaluated 2,257 medical oncology discharges representing 1,857 unique patients. We found that 65.9% of patients discharged (N = 1,489) completed at least one symptom assessment postdischarge and of them, 45.5% (n = 678) generated a severe symptom alert that we helped to manage. Patients expressed high satisfaction with the intervention with a net promoter score of 84%. In preliminary analysis of patients with GI malignancies (n = 449), we found a nonsignificant decrease in 30-day readmissions for the intervention cohort (n = 269) by 5.8% as compared with the control (n = 180; from 33.3% to 27.5%;
    Conclusion: Digital transitional care management was feasible and demonstrated that patients transitioning from the hospital to home have a substantial symptom burden. The intervention was associated with high patient satisfaction but will require further refinement and evaluation to increase its impact on 30-day readmission.
    MeSH term(s) Humans ; Transitional Care/standards ; Male ; Female ; Middle Aged ; Aged ; Neoplasms/therapy ; Medical Oncology/methods ; Patient Discharge ; Telemedicine/methods ; Adult
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.23.00565
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  7. Article ; Online: Mortality Associated With Intubation and Mechanical Ventilation in Patients with COVID-19

    Zimmerman, P. / Stroever, S. / Burton, T. / Hester, K. / Kim, M. / Fahy, R. / Corbitt, K. / Petrini, J. / Nicastro, J.

    Abstract: Objective: The need for critical care, hemodynamic support, renal replacement therapy, and mechanical ventilation have emerged as key features of the SARS-nCoV-2 (COVID-19) pandemic. The primary aim of this study was to determine the in-hospital ... ...

    Abstract Objective: The need for critical care, hemodynamic support, renal replacement therapy, and mechanical ventilation have emerged as key features of the SARS-nCoV-2 (COVID-19) pandemic. The primary aim of this study was to determine the in-hospital mortality rate of mechanically ventilated patients. We also sought to determine the risk of in-hospital mortality by age, gender, race, ethnicity, and body mass index. Methods: We performed a retrospective cohort study to determine the mortality rate among inpatient adults with COVID-19 on mechanical ventilation in the Nuvance Health system between March 1, 2020 and July 17, 2020. Patients were included if they were 18 years or older, had a laboratory confirmed COVID-19 diagnosis, were admitted to hospitals within the Nuvance Health network (7 hospitals), and were on mechanical ventilation at any time during their inpatient stay. Results: Overall mortality in our cohort of 304 patients was 53.3 percent. Multivariable logistic regression including age, gender, race, ethnicity, and BMI demonstrated patients over 71 years old had greater risk of mortality compared to patients ages 61-70, and females had half the risk compared to males. There was no significant difference in risk of mortality given race, ethnicity, or BMI. Conclusions: In adult patients with confirmed COVID-19 infection requiring mechanical ventilation and intensive care, advanced age (>71 years old) and male gender are associated with increased risk of mortality. This information contributes to a collective body of evidence to support ongoing planning and decision-making among clinicians and for directed infection prevention programming.
    Keywords covid19
    Publisher MedRxiv; WHO
    Document type Article ; Online
    DOI 10.1101/2020.08.13.20174524
    Database COVID19

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  8. Article ; Online: Paraneoplastic sarcoidosis: a review.

    Herron, M / Chong, S G / Gleeson, L / Nicholson, S / Fahy, R J

    QJM : monthly journal of the Association of Physicians

    2019  Volume 113, Issue 1, Page(s) 17–19

    Abstract: Background: Sarcoidosis is occasionally seen in association with malignancy, both at the time of cancer diagnosis or during follow up.: Aim: The purpose of this study is to identify patients with paraneoplastic sarcoid, their associated malignancies ... ...

    Abstract Background: Sarcoidosis is occasionally seen in association with malignancy, both at the time of cancer diagnosis or during follow up.
    Aim: The purpose of this study is to identify patients with paraneoplastic sarcoid, their associated malignancies and disease characteristics.
    Methods: We identified 289 patients diagnosed histologically with sarcoidosis over a 6-year period in one centre, from 2010 to 2016. Fifty of these patients had a prior or concomitant diagnosis of cancer.
    Results: 17.3% of sarcoid cases had an associated malignancy. The most common malignancies were Gastrointestinal (20%), Haematological (18%), Lung (12%), Gynaecological (12%) and Head and Neck cancer (12%). 74% of sarcoid cases had pulmonary disease with sarcoid diagnostic tissue obtained most frequently via endobronchial ultrasound fine needle aspiration (68%). Most sarcoid cases (66%) were diagnosed within the first year of their malignancy diagnosis.
    Discussion: Careful consideration needs to be given to the possibility that potential cancer recurrences suspected on imaging studies may indeed be sarcoid reactions.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Biopsy, Fine-Needle ; Endosonography ; Female ; Humans ; Ireland ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Neoplasms/pathology ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Sarcoidosis/diagnosis ; Sarcoidosis/epidemiology ; Sarcoidosis/pathology ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2019-08-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcz207
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  9. Article ; Online: Pneumothorax and empyema complicating Scedosporium apiospermum mycetoma: not just a problem in the immunocompromised patients.

    Hassan, T / Nicholson, S / Fahy, R

    Irish journal of medical science

    2010  Volume 180, Issue 4, Page(s) 931–932

    MeSH term(s) Adult ; Antifungal Agents/therapeutic use ; Empyema/complications ; Humans ; Lung Diseases, Fungal/complications ; Lung Diseases, Fungal/microbiology ; Male ; Mycetoma/complications ; Mycetoma/drug therapy ; Mycetoma/microbiology ; Pneumothorax/complications ; Scedosporium ; Triazoles/therapeutic use
    Chemical Substances Antifungal Agents ; Triazoles ; posaconazole (6TK1G07BHZ)
    Language English
    Publishing date 2010-10-21
    Publishing country Ireland
    Document type Letter
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-010-0621-0
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  10. Article ; Online: Association of subcellular localization of TEAD transcription factors with outcome and progression in pancreatic ductal adenocarcinoma.

    Drexler, Richard / Fahy, Rebecca / Küchler, Mirco / Wagner, Kim C / Reese, Tim / Ehmke, Mareike / Feyerabend, Bernd / Kleine, Moritz / Oldhafer, Karl J

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

    2020  Volume 21, Issue 1, Page(s) 170–179

    Abstract: Background: Transcriptional enhanced associated domain (TEAD) transcription factors are nuclear effectors of several oncogenic signalling pathways including Hippo, WNT, TGF-ß and EGFR pathways that interact with various cancer genes. The subcellular ... ...

    Abstract Background: Transcriptional enhanced associated domain (TEAD) transcription factors are nuclear effectors of several oncogenic signalling pathways including Hippo, WNT, TGF-ß and EGFR pathways that interact with various cancer genes. The subcellular localization of TEAD regulates the functional output of these pathways affecting tumour progression and patient outcome. However, the impact of the TEAD family on pancreatic ductal adenocarcinoma (PDAC) and its clinical progression remain elusive.
    Methods: A cohort of 81 PDAC patients who had undergone surgery was established. Cytoplasmic and nuclear localization of TEAD1, TEAD2, TEAD3 and TEAD4 was evaluated with the immunoreactive score (IRS) by immunohistochemistry (IHC) using paraffin-embedded tissue. Results were correlated with clinicopathological data, disease-free and overall survival.
    Results: Nuclear staining of all four TEADs was increased in pancreatic cancer tissue. Patients suffering from metastatic disease at time of surgery showed a strong nuclear staining of TEAD2 and TEAD3 (p < 0.05). Furthermore, a nuclear > cytoplasmic ratio of TEAD2 and TEAD3 was associated with a shorter overall survival and TEAD2 emerged as an independent prognostic factor for disease-free survival.
    Conclusion: Our study underlines the importance of TEAD transcription factors in PDAC as a nuclear localization was found to be associated with metastatic disease and an unfavourable prognosis after surgical resection.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Carcinoma, Pancreatic Ductal/genetics ; Carcinoma, Pancreatic Ductal/metabolism ; Carcinoma, Pancreatic Ductal/mortality ; Cell Nucleus/metabolism ; Cohort Studies ; Cytoplasm/metabolism ; DNA-Binding Proteins/genetics ; Disease Progression ; Female ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Metastasis ; Pancreatectomy ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/surgery ; Subcellular Fractions/metabolism ; Survival Analysis ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Chemical Substances Biomarkers, Tumor ; DNA-Binding Proteins ; TEAD2 protein, human ; TEAD3 protein, human ; Transcription Factors
    Language English
    Publishing date 2020-12-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2056680-3
    ISSN 1424-3911 ; 1424-3903
    ISSN (online) 1424-3911
    ISSN 1424-3903
    DOI 10.1016/j.pan.2020.12.003
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