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  1. Article ; Online: Escape room to operating room: A potential training modality?

    Jenkin, Ifan / Fairhurst, Natalie

    Medical teacher

    2019  Volume 42, Issue 5, Page(s) 596

    MeSH term(s) Clinical Competence ; Curriculum ; Operating Rooms
    Language English
    Publishing date 2019-08-26
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424426-6
    ISSN 1466-187X ; 0142-159X
    ISSN (online) 1466-187X
    ISSN 0142-159X
    DOI 10.1080/0142159X.2019.1657821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Staff perceptions and challenges of the single-family room design-Experience of a greenfield level4 neonatal intensive care unit in the Middle East.

    Soni, Roopali / Fairhurst, Natalie / El Anbari, Mohammed / Leslie, Ana / Tscherning Wel-Wel, Charlotte

    Acta paediatrica (Oslo, Norway : 1992)

    2022  Volume 111, Issue 12, Page(s) 2291–2298

    Abstract: Aim: This study was undertaken to specifically identify challenges associated with the popular single-family room (SFR) design in our new neonatal intensive care unit (NICU), so as to reap the full benefits of this architectural model.: Methods: A ... ...

    Abstract Aim: This study was undertaken to specifically identify challenges associated with the popular single-family room (SFR) design in our new neonatal intensive care unit (NICU), so as to reap the full benefits of this architectural model.
    Methods: A survey was sent to all 223, newly recruited staff on our NICU. Questions explored staff perceptions of family experience, safety and staff's experience of the SFR in comparison with the open bay model.
    Results: We obtained a response rate of 66%. Most staff perceived SFR as having a positive impact on communication with families, privacy, feasibility for skin-to-skin contact, reduction in noise levels and family access to their baby. There were however concerns raised about patient safety and isolation of staff and families in the SFR architecture. Lack of opportunities to leave the patient room for breaks and increased physical demands were highlighted. Staff also felt physically and emotionally less well supported.
    Conclusion: Whilst the SFR configuration was felt to be beneficial for infants and families, staff shared their perceived concerns regarding infant safety and isolation and staff satisfaction, and implied modifications to workflows. The survey findings resulted in re-organisation of our staff numbers and communication systems and further facilitation of parent interactions in order to optimise benefits of SFR design.
    MeSH term(s) Infant, Newborn ; Infant ; Humans ; Intensive Care Units, Neonatal ; Patients' Rooms ; Parents/psychology ; Surveys and Questionnaires ; Communication
    Language English
    Publishing date 2022-09-01
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.16527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Why is it so difficult to evaluate faecal microbiota transplantation as a treatment for ulcerative colitis?

    Fairhurst, Natalie Grace / Travis, Simon P L

    Intestinal research

    2018  Volume 16, Issue 2, Page(s) 209–215

    Abstract: Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment ... ...

    Abstract Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment of
    Language English
    Publishing date 2018-04-30
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 3018469-1
    ISSN 2288-1956 ; 1598-9100
    ISSN (online) 2288-1956
    ISSN 1598-9100
    DOI 10.5217/ir.2018.16.2.209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Artificial intelligence methods for improved detection of undiagnosed heart failure with preserved ejection fraction.

    Wu, Jack / Biswas, Dhruva / Ryan, Matthew / Bernstein, Brett S / Rizvi, Maleeha / Fairhurst, Natalie / Kaye, George / Baral, Ranu / Searle, Tom / Melikian, Narbeh / Sado, Daniel / Lüscher, Thomas F / Grocott-Mason, Richard / Carr-White, Gerald / Teo, James / Dobson, Richard / Bromage, Daniel I / McDonagh, Theresa A / Shah, Ajay M /
    O'Gallagher, Kevin

    European journal of heart failure

    2024  Volume 26, Issue 2, Page(s) 302–310

    Abstract: Aim: Heart failure with preserved ejection fraction (HFpEF) remains under-diagnosed in clinical practice despite accounting for nearly half of all heart failure (HF) cases. Accurate and timely diagnosis of HFpEF is crucial for proper patient management ... ...

    Abstract Aim: Heart failure with preserved ejection fraction (HFpEF) remains under-diagnosed in clinical practice despite accounting for nearly half of all heart failure (HF) cases. Accurate and timely diagnosis of HFpEF is crucial for proper patient management and treatment. In this study, we explored the potential of natural language processing (NLP) to improve the detection and diagnosis of HFpEF according to the European Society of Cardiology (ESC) diagnostic criteria.
    Methods and results: In a retrospective cohort study, we used an NLP pipeline applied to the electronic health record (EHR) to identify patients with a clinical diagnosis of HF between 2010 and 2022. We collected demographic, clinical, echocardiographic and outcome data from the EHR. Patients were categorized according to the left ventricular ejection fraction (LVEF). Those with LVEF ≥50% were further categorized based on whether they had a clinician-assigned diagnosis of HFpEF and if not, whether they met the ESC diagnostic criteria. Results were validated in a second, independent centre. We identified 8606 patients with HF. Of 3727 consecutive patients with HF and LVEF ≥50% on echocardiogram, only 8.3% had a clinician-assigned diagnosis of HFpEF, while 75.4% met ESC criteria but did not have a formal diagnosis of HFpEF. Patients with confirmed HFpEF were hospitalized more frequently; however the ESC criteria group had a higher 5-year mortality, despite being less comorbid and experiencing fewer acute cardiovascular events.
    Conclusions: This study demonstrates that patients with undiagnosed HFpEF are an at-risk group with high mortality. It is possible to use NLP methods to identify likely HFpEF patients from EHR data who would likely then benefit from expert clinical review and complement the use of diagnostic algorithms.
    MeSH term(s) Humans ; Heart Failure ; Stroke Volume ; Ventricular Function, Left ; Artificial Intelligence ; Retrospective Studies ; Prognosis
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.3115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5299: Show issues Location:
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  5. Article ; Online: An active fixation quadripolar left ventricular lead for cardiac resynchronization therapy with reduced postoperative complication rates.

    Robertson, Calum / Duffey, Owen / Tang, Pok-Tin / Fairhurst, Natalie / Monteiro, Cristiana / Green, Peregrine / Grogono, Joanna / Davies, Mark / Lewis, Andrew / Wijesurendra, Rohan / Ormerod, Julian / Gamble, James / Ginks, Matthew / Rajappan, Kim / Bashir, Yaver / Betts, Tim R / Herring, Neil

    Journal of cardiovascular electrophysiology

    2022  Volume 33, Issue 3, Page(s) 458–463

    Abstract: Background: The rate of left ventricular (LV) lead displacement after cardiac resynchronization therapy (CRT) remains high despite improvements in lead technology. In 2017, a novel quadripolar lead with active fixation technology became available in the ...

    Abstract Background: The rate of left ventricular (LV) lead displacement after cardiac resynchronization therapy (CRT) remains high despite improvements in lead technology. In 2017, a novel quadripolar lead with active fixation technology became available in the UK.
    Methods: This was a retrospective, observational study analyzing device complications in 476 consecutive patients undergoing successful first-time implantation of a CRT device at a tertiary center from 2017 to 2020.
    Results: Both active (n = 135) and passive fixation (n = 341) quadripolar leads had similar success rates for implantation (99.3% vs. 98.8%, p = 1.00), although the pacing threshold (0.89 [0.60-1.25] vs. 1.00 [0.70-1.60] V, p = .01) and lead impedance (632 [552-794] vs. 730 [636-862] Ohms, p < .0001) were significantly lower for the active fixation lead. Patients receiving an active fixation lead had a reduced incidence of lead displacement at 6 months (0.74% vs. 4.69%, p = .036). There was no significant difference in the rate of right atrial (RA) and right ventricular (RV) lead displacement between the two groups (RA: 1.48% vs. 1.17%, p = .68; RV: 2.22% vs. 1.76%, p = .72). Reprogramming the LV lead after displacement was unsuccessful in most cases (successful reprogramming: Active fix = 0/1, Passive fix = 1/16) therefore nearly all patients required a repeat procedure. As a result, the rate of intervention within 6 months for lead displacement was significantly lower when patients were implanted with the active fixation lead (0.74% vs. 4.40%, p = .049).
    Conclusion: The novel active fixation lead in our study has a lower incidence of lead displacement and re-intervention compared to conventional quadripolar leads for CRT.
    MeSH term(s) Cardiac Resynchronization Therapy/adverse effects ; Cardiac Resynchronization Therapy/methods ; Cardiac Resynchronization Therapy Devices ; Electrodes, Implanted/adverse effects ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Postoperative Complications/therapy ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-01-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2863: Show issues Location:
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