Artikel ; Online: Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis.
Molecules (Basel, Switzerland)
2023 Band 28, Heft 13
Abstract: This review uses the National Cancer Institute (NCI) COMPARE program to establish an extensive list of heterocyclic iminoquinones and quinones with similarities in differential growth inhibition patterns across the 60-cell line panel of the NCI ... ...
| Abstract | This review uses the National Cancer Institute (NCI) COMPARE program to establish an extensive list of heterocyclic iminoquinones and quinones with similarities in differential growth inhibition patterns across the 60-cell line panel of the NCI Developmental Therapeutics Program (DTP). Many natural products and synthetic analogues are revealed as potential NAD(P)H:quinone oxidoreductase 1 (NQO1) substrates, through correlations to dipyridoimidazo[5,4- |
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| Mesh-Begriff(e) | United States ; National Cancer Institute (U.S.) ; Quinones/chemistry ; Indolequinones ; Oxidoreductases ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Neoplasms | |||||
| Chemische Substanzen | iminoquinone ; quinone (3T006GV98U) ; Quinones ; Indolequinones ; Oxidoreductases (EC 1.-) ; NAD(P)H Dehydrogenase (Quinone) (EC 1.6.5.2) ; Antineoplastic Agents | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2023-07-04 | |||||
| Erscheinungsland | Switzerland | |||||
| Dokumenttyp | Journal Article ; Review | |||||
| ZDB-ID | 1413402-0 | |||||
| ISSN | 1420-3049 ; 1431-5165 ; 1420-3049 | |||||
| ISSN (online) | 1420-3049 | |||||
| ISSN | 1431-5165 ; 1420-3049 | |||||
| DOI | 10.3390/molecules28135202 | |||||
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| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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Verfügbar in ZB MED Köln/Königswinter
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