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Article ; Online: Clinical features of patients inappropriately undiagnosed of pulmonary embolism.

Torres-Macho, Juan / Mancebo-Plaza, Ana B / Crespo-Giménez, Ana / Sanz de Barros, M Rosa / Bibiano-Guillén, Carlos / Fallos-Martí, Raúl / Calderón-Parra, Jorge / de Miguel-Yanes, José M

The American journal of emergency medicine

2013  Volume 31, Issue 12, Page(s) 1646–1650

Abstract: Purposes: The objective of this study was to identify clinical factors associated with delayed diagnosis of acute pulmonary embolism (PE) in the emergency department (ED).: Basic procedures: A retrospective observational study was performed at three ... ...

Abstract Purposes: The objective of this study was to identify clinical factors associated with delayed diagnosis of acute pulmonary embolism (PE) in the emergency department (ED).
Basic procedures: A retrospective observational study was performed at three University affiliated Hospitals; 436 consecutive patients who presented to the ED with an acute PE confirmed by chest computed tomography from 2008 to 2011 were included. Patients were divided into 3 groups: group 1, PE was diagnosed while the patient was still in the ED; group 2, PE was diagnosed during hospitalization; group 3, patients who were sent home with a wrong alternative diagnosis and returned to the ED and were diagnosed of PE.
Main findings: One hundred forty-six patients (33.5%) had a delayed diagnosis of PE--21.5% belong to group 2 and 11.9% to Group 3. Chronic coexisting medical conditions like asthma or chronic obstructive pulmonary disease were independent predictors of a delayed diagnosis in patients who were admitted to hospital whereas non-specific and less severe symptoms like the presence of pleuro-mechanic thoracic pain, fever, hemoptysis, or the presence of a pulmonary infiltrate in chest x-ray were independent predictors of a delayed diagnosis in patients who were sent home.
Principal conclusions: Delay in diagnosis of acute PE is frequent despite current diagnostic strategies. Patients are sent home or admitted to hospital with a wrong diagnosis depending on clinical presentation or coexisting medical conditions.
MeSH term(s) Age Distribution ; Aged ; Aged, 80 and over ; Chest Pain/etiology ; Comorbidity ; Coronary Artery Disease/epidemiology ; Cough/etiology ; Delayed Diagnosis/statistics & numerical data ; Diabetes Mellitus/epidemiology ; Diagnostic Errors/statistics & numerical data ; Emergency Service, Hospital ; Female ; Heart Failure/epidemiology ; Hemoptysis/etiology ; Humans ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; Risk Factors ; Smoking/epidemiology ; Tomography, X-Ray Computed
Language English
Publishing date 2013-12
Publishing country United States
Document type Journal Article ; Observational Study
ZDB-ID 605890-5
ISSN 1532-8171 ; 0735-6757
ISSN (online) 1532-8171
ISSN 0735-6757
DOI 10.1016/j.ajem.2013.08.037
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