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  1. Article ; Online: Synthesis of CoMoO

    Fan, Jiahui / Chang, Xin / Li, Lu / Zhang, Mingyi

    Molecules (Basel, Switzerland)

    2023  Volume 29, Issue 1

    Abstract: To improve the traditional energy production and consumption of resources, the acceleration of the development of a clean and green assembly line is highly important. Hydrogen is considered one of the most ideal options. The method of production of ... ...

    Abstract To improve the traditional energy production and consumption of resources, the acceleration of the development of a clean and green assembly line is highly important. Hydrogen is considered one of the most ideal options. The method of production of hydrogen through water splitting constitutes the most attractive research. We synthesized CoMoO
    Language English
    Publishing date 2023-12-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29010007
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  2. Article: The Function and Therapeutic Potential of lncRNAs in Cardiac Fibrosis.

    Nie, Xiang / Fan, Jiahui / Wang, Dao Wen

    Biology

    2023  Volume 12, Issue 2

    Abstract: Cardiac fibrosis remains an unresolved problem in cardiovascular diseases. Fibrosis of the myocardium plays a key role in the clinical outcomes of patients with heart injuries. Moderate fibrosis is favorable for cardiac structure maintaining and ... ...

    Abstract Cardiac fibrosis remains an unresolved problem in cardiovascular diseases. Fibrosis of the myocardium plays a key role in the clinical outcomes of patients with heart injuries. Moderate fibrosis is favorable for cardiac structure maintaining and contractile force transmission, whereas adverse fibrosis generally progresses to ventricular remodeling and cardiac systolic or diastolic dysfunction. The molecular mechanisms involved in these processes are multifactorial and complex. Several molecular mechanisms, such as TGF-β signaling pathway, extracellular matrix (ECM) synthesis and degradation, and non-coding RNAs, positively or negatively regulate myocardial fibrosis. Long noncoding RNAs (lncRNAs) have emerged as significant mediators in gene regulation in cardiovascular diseases. Recent studies have demonstrated that lncRNAs are crucial in genetic programming and gene expression during myocardial fibrosis. We summarize the function of lncRNAs in cardiac fibrosis and their contributions to miRNA expression, TGF-β signaling, and ECMs synthesis, with a particular attention on the exosome-derived lncRNAs in the regulation of adverse fibrosis as well as the mode of action of lncRNAs secreted into exosomes. We also discuss how the current knowledge on lncRNAs can be applied to develop novel therapeutic strategies to prevent or reverse cardiac fibrosis.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12020154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Function and Therapeutic Potential of lncRNAs in Cardiac Fibrosis

    Nie, Xiang / Fan, Jiahui / Wang, Daowen

    Biology (Basel). 2023 Jan. 19, v. 12, no. 2

    2023  

    Abstract: Cardiac fibrosis remains an unresolved problem in cardiovascular diseases. Fibrosis of the myocardium plays a key role in the clinical outcomes of patients with heart injuries. Moderate fibrosis is favorable for cardiac structure maintaining and ... ...

    Abstract Cardiac fibrosis remains an unresolved problem in cardiovascular diseases. Fibrosis of the myocardium plays a key role in the clinical outcomes of patients with heart injuries. Moderate fibrosis is favorable for cardiac structure maintaining and contractile force transmission, whereas adverse fibrosis generally progresses to ventricular remodeling and cardiac systolic or diastolic dysfunction. The molecular mechanisms involved in these processes are multifactorial and complex. Several molecular mechanisms, such as TGF-β signaling pathway, extracellular matrix (ECM) synthesis and degradation, and non-coding RNAs, positively or negatively regulate myocardial fibrosis. Long noncoding RNAs (lncRNAs) have emerged as significant mediators in gene regulation in cardiovascular diseases. Recent studies have demonstrated that lncRNAs are crucial in genetic programming and gene expression during myocardial fibrosis. We summarize the function of lncRNAs in cardiac fibrosis and their contributions to miRNA expression, TGF-β signaling, and ECMs synthesis, with a particular attention on the exosome-derived lncRNAs in the regulation of adverse fibrosis as well as the mode of action of lncRNAs secreted into exosomes. We also discuss how the current knowledge on lncRNAs can be applied to develop novel therapeutic strategies to prevent or reverse cardiac fibrosis.
    Keywords exosomes ; extracellular matrix ; fibrosis ; gene expression ; genes ; mechanism of action ; microRNA ; myocardium ; therapeutics
    Language English
    Dates of publication 2023-0119
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12020154
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Enhancing Solar-Driven Water Purification by Multiscale Biomimetic Evaporators Featuring Lamellar MoS

    Zheng, Haotian / Fan, Jiahui / Chen, Aiying / Li, Xiang / Xie, Xiaofeng / Liu, Yong / Ding, Zhiyi

    ACS nano

    2024  Volume 18, Issue 4, Page(s) 3115–3124

    Abstract: Solar-powered steam generation holds a strong sustainability in facing the global water crisis, while the production efficiency and antifouling performance remain challenges. Inspired by river moss, a multiscale biomimetic evaporator is designed, where ... ...

    Abstract Solar-powered steam generation holds a strong sustainability in facing the global water crisis, while the production efficiency and antifouling performance remain challenges. Inspired by river moss, a multiscale biomimetic evaporator is designed, where the key photothermal conversion film composed of lamellar MoS
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.3c08648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Synthesis, characterization, and antibacterial activity of chitosan-chelated silver nanoparticles.

    Ge, Jiu / Li, Mengting / Fan, Jiahui / Celia, Christian / Xie, Yijun / Chang, Qing / Deng, Xiaoyong

    Journal of biomaterials science. Polymer edition

    2024  Volume 35, Issue 1, Page(s) 45–62

    Abstract: Bacterial infections pose a significant threat to human health and safety, necessitating the urgent resolution of the problem through the development and implementation of highly effective antibacterial agents. However, the emergence of multidrug- ... ...

    Abstract Bacterial infections pose a significant threat to human health and safety, necessitating the urgent resolution of the problem through the development and implementation of highly effective antibacterial agents. However, the emergence of multidrug-resistant bacteria has diminished the satisfactory effectiveness of antibacterial treatments. To overcome this obstacle, we developed effective antibacterial agents by chemical reduction for inhibiting bacterial proliferation and inducing membrane damage. Specifically, four different types of chitosan/Ag nanoparticle (CS-AgNPs-
    MeSH term(s) Humans ; Silver/pharmacology ; Silver/chemistry ; Metal Nanoparticles/chemistry ; Chitosan/pharmacology ; Chitosan/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Staphylococcus aureus ; Escherichia coli ; Microbial Sensitivity Tests
    Chemical Substances Silver (3M4G523W1G) ; Chitosan (9012-76-4) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1014190-x
    ISSN 1568-5624 ; 1568-5616 ; 0920-5063
    ISSN (online) 1568-5624 ; 1568-5616
    ISSN 0920-5063
    DOI 10.1080/09205063.2023.2265629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2931: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

    Xie, Peiwei / Luo, Mei / Deng, Xuehong / Fan, Jiahui / Xiong, Lishou

    Nutrients

    2023  Volume 15, Issue 17

    Abstract: Irritable bowel syndrome (IBS) is a common gastrointestinal disease. The efficacy of different probiotics in treating IBS remains controversial. This network meta-analysis aimed to compare and rank the outcome-specific efficacy of different probiotic ... ...

    Abstract Irritable bowel syndrome (IBS) is a common gastrointestinal disease. The efficacy of different probiotics in treating IBS remains controversial. This network meta-analysis aimed to compare and rank the outcome-specific efficacy of different probiotic strains or combinations in adults with IBS. We searched the literature up to June 2023. Randomized controlled trials (RCTs) that evaluated the efficacy of probiotics in IBS were included. A frequentist framework was used to perform this study. In total, 9253 participants from 81 RCTs were included in the study. Four probiotic strains and five mixtures were significantly superior to placebo in improving IBS Symptom Severity Scale, among which
    MeSH term(s) Adult ; Humans ; Irritable Bowel Syndrome/therapy ; Network Meta-Analysis ; Abdominal Pain/therapy ; Bacillus coagulans ; Probiotics/therapeutic use ; Saccharomyces cerevisiae
    Language English
    Publishing date 2023-09-04
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15173856
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  7. Article ; Online: Rifaximin Ameliorates Loperamide-Induced Constipation in Rats through the Regulation of Gut Microbiota and Serum Metabolites.

    Luo, Mei / Xie, Peiwei / Deng, Xuehong / Fan, Jiahui / Xiong, Lishou

    Nutrients

    2023  Volume 15, Issue 21

    Abstract: Structural changes in the gut microbiota are closely related to the development of functional constipation, and regulating the gut microbiota can improve constipation. Rifaximin is a poorly absorbed antibiotic beneficial for regulating gut microbiota, ... ...

    Abstract Structural changes in the gut microbiota are closely related to the development of functional constipation, and regulating the gut microbiota can improve constipation. Rifaximin is a poorly absorbed antibiotic beneficial for regulating gut microbiota, but few studies have reported its effects on constipation. The purpose of this study was to investigate the effect of rifaximin on loperamide-induced constipation in SD rats. The results showed that rifaximin improved constipation by increasing serum 5-HT, SP, and the mRNA expression of AQP3, AQP8, and reducing the mRNA expression of TLR2 and TLR4. In addition, rifaximin could regulate the gut microbiota of constipated rats, such as increasing the potentially beneficial bacteria
    MeSH term(s) Rats ; Animals ; Loperamide/adverse effects ; Rifaximin/adverse effects ; Gastrointestinal Microbiome ; Rats, Sprague-Dawley ; Constipation/chemically induced ; Constipation/drug therapy ; RNA, Messenger
    Chemical Substances Loperamide (6X9OC3H4II) ; Rifaximin (L36O5T016N) ; RNA, Messenger
    Language English
    Publishing date 2023-10-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15214502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: LncRNA MIR217HG aggravates pressure-overload induced cardiac remodeling by activating miR-138/THBS1 pathway.

    Nie, Xiang / Xie, Rong / Fan, Jiahui / Wang, Dao Wen

    Life sciences

    2023  Volume 336, Page(s) 122290

    Abstract: Aim: Cardiac hypertrophy and fibrosis are associated with cardiac remodeling and heart failure. We have previously shown that miRNA-217, embedded within the third intron of MIR217HG, aggravates pressure overload-induced cardiac hypertrophy by targeting ... ...

    Abstract Aim: Cardiac hypertrophy and fibrosis are associated with cardiac remodeling and heart failure. We have previously shown that miRNA-217, embedded within the third intron of MIR217HG, aggravates pressure overload-induced cardiac hypertrophy by targeting phosphatase and tensin homolog. However, whether the MIR217HG transcript itself plays a role in cardiac remodeling remains unknown.
    Methods: Real-time PCR assays and RNA in situ hybridization were performed to detect MIR217HG expression. Lentiviruses and adeno-associated viruses with a cardiac-specific promoter (cTnT) were used to control MIR217HG expression in vitro and in vivo. Transverse aortic constriction (TAC) surgery was performed to develop cardiac remodeling models. Cardiac structure and function were analyzed using echocardiography and invasive pressure-volume analysis.
    Key findings: MIR217HG expression was increased in patients with heart failure. MIR217HG overexpression aggravated pressure-overload-induced myocyte hypertrophy and fibrosis both in vivo and in vitro, whereas MIR217HG knockdown reversed these phenotypes. Mechanistically, MIR217HG increased THBS1 expression by sponging miR-138. MiR-138 recognized the 3'UTR of THBS1 and repressed THBS1 expression in the absence of MIR217HG. Silencing THBS1 expression reversed MIR217HG-induced cardiac hypertrophy and remodeling.
    Conclusion: MIR217HG acts as a potent inducer of cardiac remodeling that may contribute to heart failure by activating the miR-138/THBS1 pathway.
    MeSH term(s) Humans ; Animals ; Mice ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Ventricular Remodeling/genetics ; Cardiomegaly/genetics ; Cardiomegaly/metabolism ; Heart Failure/genetics ; Heart Failure/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Fibrosis ; Myocytes, Cardiac/metabolism ; Mice, Inbred C57BL
    Chemical Substances RNA, Long Noncoding ; MicroRNAs ; MIRN217 microRNA, human ; MIRN138 microRNA, human ; MIRN-217 microRNA, mouse
    Language English
    Publishing date 2023-11-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3378-9
    ISSN 1879-0631 ; 0024-3205
    ISSN (online) 1879-0631
    ISSN 0024-3205
    DOI 10.1016/j.lfs.2023.122290
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    Uc I Zs.368: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Photodegradation of N-nitrosodimethylamine under 365 nm Light Emitting Diode Irradiation.

    Fan, Jiahui / Deng, Cun / Rao, Yongfang

    Water environment research : a research publication of the Water Environment Federation

    2022  Volume 94, Issue 9, Page(s) e10787

    Abstract: The photodegradation of NDMA has been extensively investigated under the irradiation of low-pressure or medium-pressure Hg lamps and xenon lamp. However, NDMA photolysis remains unknown under 365 nm ultraviolet light-emitting diode (UV-LED) irradiation. ... ...

    Abstract The photodegradation of NDMA has been extensively investigated under the irradiation of low-pressure or medium-pressure Hg lamps and xenon lamp. However, NDMA photolysis remains unknown under 365 nm ultraviolet light-emitting diode (UV-LED) irradiation. This study conducted a comprehensive investigation on NDMA photodegradation by 365 nm UV-LED illumination. The quantum yield of NDMA photolysis under 365 nm UV-LED irradiation was determined to be 0.0312 ± 0.0047. The influence of pH on NDMA photodegradation was found to be wavelength dependent. Compared with distilled and deionized water (DDW), tap water inhibited NDMA photodegradation, but secondary wastewater effluent did not. Based on the quantification of NDMA photolysis products and pH influence, the photooxidation of the excited NDMA in the nonprotonated form was proposed to be a major pathway for NDMA photodegradation under the irradiation of UV-LED lamp at 365 nm. This study further enhances our knowledge on NDMA photodegradation. PRACTITIONER POINTS: Quantum yield of NDMA photolysis at 365 nm was determined to be 0.0312 ± 0.0047. The influence of pH on NDMA photodegradation was wavelength dependent. NDMA photodegradation was inhibited in tap water compared with that in DDW. NDMA photodegradation in SWE was similar to that in DDW. Excited nonprotonated NDMA photooxidation is a major degradation pathway.
    Language English
    Publishing date 2022-08-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1098976-6
    ISSN 1554-7531 ; 1047-7624 ; 1061-4303
    ISSN (online) 1554-7531
    ISSN 1047-7624 ; 1061-4303
    DOI 10.1002/wer.10787
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 490: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Photodegradation of N‐nitrosodimethylamine under 365 nm Light Emitting Diode Irradiation

    Fan, Jiahui / Deng, Cun / Rao, Yongfang

    Water environment research. 2022 Sept., v. 94, no. 9

    2022  

    Abstract: The photodegradation of NDMA has been extensively investigated under the irradiation of low‐pressure or medium‐pressure Hg lamps and xenon lamp. However, NDMA photolysis remains unknown under 365 nm ultraviolet light‐emitting diode (UV‐LED) irradiation. ... ...

    Abstract The photodegradation of NDMA has been extensively investigated under the irradiation of low‐pressure or medium‐pressure Hg lamps and xenon lamp. However, NDMA photolysis remains unknown under 365 nm ultraviolet light‐emitting diode (UV‐LED) irradiation. This study conducted a comprehensive investigation on NDMA photodegradation by 365 nm UV‐LED illumination. The quantum yield of NDMA photolysis under 365 nm UV‐LED irradiation was determined to be 0.0312 ± 0.0047. The influence of pH on NDMA photodegradation was found to be wavelength dependent. Compared with distilled and deionized water (DDW), tap water inhibited NDMA photodegradation, but secondary wastewater effluent did not. Based on the quantification of NDMA photolysis products and pH influence, the photooxidation of the excited NDMA in the nonprotonated form was proposed to be a major pathway for NDMA photodegradation under the irradiation of UV‐LED lamp at 365 nm. This study further enhances our knowledge on NDMA photodegradation. PRACTITIONER POINTS: Quantum yield of NDMA photolysis at 365 nm was determined to be 0.0312 ± 0.0047. The influence of pH on NDMA photodegradation was wavelength dependent. NDMA photodegradation was inhibited in tap water compared with that in DDW. NDMA photodegradation in SWE was similar to that in DDW. Excited nonprotonated NDMA photooxidation is a major degradation pathway.
    Keywords N-nitrosodimethylamine ; environment ; irradiation ; light emitting diodes ; lighting ; pH ; photolysis ; photooxidation ; research ; tap water ; wastewater ; water ; wavelengths ; xenon
    Language English
    Dates of publication 2022-09
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note Case Reports
    ZDB-ID 1098976-6
    ISSN 1554-7531 ; 1047-7624 ; 1061-4303
    ISSN (online) 1554-7531
    ISSN 1047-7624 ; 1061-4303
    DOI 10.1002/wer.10787
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4344: Show issues

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