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  1. Article ; Online: Manipulation of Bowl-Shaped Nanoparticles Self-Assembled from a Bipyridine Pendant Containing Homopolymer.

    Fan, Yirong / Sun, Hui

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 11, Page(s) 5828–5836

    Abstract: The morphological control and transformation of soft nanomaterials are critical for their physical and chemical properties, which can be achieved by dynamically regulating the hydrophilicity of amphiphilic polymers during self-assembly. Herein, an ... ...

    Abstract The morphological control and transformation of soft nanomaterials are critical for their physical and chemical properties, which can be achieved by dynamically regulating the hydrophilicity of amphiphilic polymers during self-assembly. Herein, an amphiphilic homopolymer poly(
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c03712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Physically and Chemically Compartmentalized Polymersomes for Programmed Delivery and Biological Applications.

    Gao, Yaning / Gao, Chenchen / Fan, Yirong / Sun, Hui / Du, Jianzhong

    Biomacromolecules

    2023  Volume 24, Issue 12, Page(s) 5511–5538

    Abstract: Multicompartment polymersomes (MCPs) refer to polymersomes that not only contain one single compartment, either in the membrane or in the internal cavity, but also mimic the compartmentalized structure of living cells, attracting much attention in ... ...

    Abstract Multicompartment polymersomes (MCPs) refer to polymersomes that not only contain one single compartment, either in the membrane or in the internal cavity, but also mimic the compartmentalized structure of living cells, attracting much attention in programmed delivery and biological applications. The investigation of MCPs may promote the application of soft nanomaterials in biomedicine. This Review seeks to highlight the recent advances of the design principles, synthetic strategies, and biomedical applications of MCPs. The compartmentalization types including chemical, physical, and hybrid compartmentalization are discussed. Subsequently, the design and controlled synthesis of MCPs by the self-assembly of amphiphilic polymers, double emulsification, coprecipitation, microfluidics and particle assembly, etc. are summarized. Furthermore, the diverse applications of MCPs in programmed delivery of various cargoes and biological applications including cancer therapy, antimicrobials, and regulation of blood glucose levels are highlighted. Finally, future perspectives of MCPs from the aspects of controlled synthesis and applications are proposed.
    MeSH term(s) Nanostructures/chemistry ; Polymers/chemistry ; Drug Delivery Systems
    Chemical Substances Polymers
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 1526-4602
    ISSN (online) 1526-4602
    DOI 10.1021/acs.biomac.3c00826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Polymeric Toroids Derived from the Fusion-Induced Particle Assembly of Anisotropic Bowl-Shaped Nanoparticles.

    Zhou, Xiaoyan / Gao, Chenchen / Gao, Yaning / Fan, Yirong / Sun, Hui

    ACS macro letters

    2023  Volume 12, Issue 6, Page(s) 821–827

    Abstract: Polymeric toroids are fascinating soft nanostructures due to their unique geometry and properties, which have shown potential applications in the fields of nanoreactors, drug delivery, cancer therapy, etc. However, facile preparation of polymeric toroids ...

    Abstract Polymeric toroids are fascinating soft nanostructures due to their unique geometry and properties, which have shown potential applications in the fields of nanoreactors, drug delivery, cancer therapy, etc. However, facile preparation of polymeric toroids is still challenging. Herein, we propose a fusion-induced particle assembly (FIPA) strategy to prepare polymeric toroids using anisotropic bowl-shaped nanoparticles (BNPs) as a building block. The BNPs are prepared in ethanol by the self-assembly of an amphiphilic homopolymer, poly(
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    ISSN 2161-1653
    ISSN (online) 2161-1653
    DOI 10.1021/acsmacrolett.3c00175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Polymeric Bowl-Shaped Nanoparticles: Hollow Structures with a Large Opening on the Surface.

    Sun, Hui / Gao, Yaning / Fan, Yirong / Du, Jianzhong / Jiang, Jinhui / Gao, Chenchen

    Macromolecular rapid communications

    2023  Volume 44, Issue 17, Page(s) e2300196

    Abstract: Polymeric bowl-shaped nanoparticles (BNPs) are anisotropic hollow structures with large openings on the surface, which have shown advantages such as high specific area and efficient encapsulation, delivery and release of large-sized cargoes on demand ... ...

    Abstract Polymeric bowl-shaped nanoparticles (BNPs) are anisotropic hollow structures with large openings on the surface, which have shown advantages such as high specific area and efficient encapsulation, delivery and release of large-sized cargoes on demand compared to solid nanoparticles or closed hollow structures. Several strategies have been developed to prepare BNPs based on either template or template-free methods. For instance, despite the widely used self-assembly strategy, alternative methods including emulsion polymerization, swelling and freeze-drying of polymeric spheres, and template-assisted approaches have also been developed. It is attractive but still challenging to fabricate BNPs due to their unique structural features. However, there is still no comprehensive summary of BNPs up to now, which significantly hinders the further development of this field. In this review, the recent progress of BNPs will be highlighted from the perspectives of design strategies, preparation methods, formation mechanisms, and emerging applications. Moreover, the future perspectives of BNPs will also be proposed.
    MeSH term(s) Polymers/chemistry ; Nanoparticles/chemistry ; Emulsions
    Chemical Substances Polymers ; Emulsions
    Language English
    Publishing date 2023-06-09
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1475027-2
    ISSN 1521-3927 ; 1022-1336
    ISSN (online) 1521-3927
    ISSN 1022-1336
    DOI 10.1002/marc.202300196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Forage Supply–Demand Assessment and Influencing Factor Analysis from the Perspective of Socio-Ecological System: A Case Study of Altay Prefecture, China

    Yang, Zihan / Li, Bo / Nan, Bo / Li, Yuying / Huang, Kai / Bi, Xu / Fan, Yirong / Fan, Yao

    Land. 2023 May 17, v. 12, no. 5

    2023  

    Abstract: The provision and utilization of grassland resources connect grassland ecosystems and pastoral society. Revealing the mechanism behind the forage supply–demand relationship and balancing forage supply and demand is essential in pastoral socio-ecological ... ...

    Abstract The provision and utilization of grassland resources connect grassland ecosystems and pastoral society. Revealing the mechanism behind the forage supply–demand relationship and balancing forage supply and demand is essential in pastoral socio-ecological systems. Taking Altay Prefecture as the case study, this study quantified the dynamics of natural forage supply, artificial supplemental forage, and forage demand. The ratio of forage supply to demand was calculated in the traditional grazing scenario and the grazing prohibition and supplemental feeding scenario. The results showed that during 2001–2018, the forage supplied by natural grasslands fluctuated, with the highest and lowest values in 2013 and 2008, respectively. The artificial supplemental forage increased at a higher rate in 2011–2018 than in 2001–2010. The overall trend of forage demand was upward, at approximately 2.98 × 10⁴ t/a. The ratio of forage supply to demand decreased in the traditional scenario with an average value of 0.4717 and increased in the grazing prohibition and supplemental feeding scenario with an average value of 0.8289. The influencing factors were analyzed from the perspective of the interactions between the socio-ecological system elements, and the forage supply–demand relationships were conceptualized based on the social–ecological system framework. This study concludes that natural grasslands cannot entirely meet the increasing forage demand without artificial supplemental forage. The increasing artificial supplemental forage has promoted a balance between forage supply and demand, indicating an optimized grassland utilization pattern. The factors that affect forage supply–demand relationships are interrelated, and a holistic perspective should be adopted when implementing management measures.
    Keywords case studies ; factor analysis ; forage ; grasslands ; land ; pastoralism ; social environment ; supply balance ; China
    Language English
    Dates of publication 2023-0517
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2682955-1
    ISSN 2073-445X
    ISSN 2073-445X
    DOI 10.3390/land12051079
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: [Analysis of polymorphic RAPD fragments in P. Taiwanensis Hayata using an integrated microflluidic chip-based system].

    Tang, Juan-Juan / Wu, Jiang-Lin / Liu, Jin-Hua / Fan, Yi-Rong / Zhu, Mu-Yuan

    Yi chuan = Hereditas

    2003  Volume 25, Issue 4, Page(s) 419–424

    Abstract: Randomly amplified polymorphic DNA (RAPD) markers quickly provide linkage information, especially in conifers where haploid megagametophytes can be used for genotyping. Traditionally use of slab gel electrophresis results in qualitative data that can be ... ...

    Abstract Randomly amplified polymorphic DNA (RAPD) markers quickly provide linkage information, especially in conifers where haploid megagametophytes can be used for genotyping. Traditionally use of slab gel electrophresis results in qualitative data that can be manually manipulated to gain semiquantitative information about the polymorphic RAPD fragments. We have proposed the use of an integrated microfluidic chip-based system as a new tool in the analysis of polymorphic RAPD fragments. The chip-based method was found to be very sensitive,requiring much less sample and only quarter the time compared to the agarose gel method. The automated data analysis sizes and quantitates the DNA fragments, thus yielding a more thorough,reproducible, sensitive, and rapid analysis.
    Language Chinese
    Publishing date 2003-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0253-9772
    ISSN 0253-9772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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