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  1. Article: Blunt Thoracic Aortic Injury.

    Mazzaccaro, Daniela / Righini, Paolo / Fancoli, Fabiana / Giannetta, Matteo / Modafferi, Alfredo / Malacrida, Giovanni / Nano, Giovanni

    Journal of clinical medicine

    2023  Volume 12, Issue 8

    Abstract: Blunt thoracic aortic injury (BTAI) is a potentially fatal condition that needs prompt recognition and expedited management. Clinical manifestations of BTAI are not straight forwarding and may be misdiagnosed. The grade of aortic injury is an important ... ...

    Abstract Blunt thoracic aortic injury (BTAI) is a potentially fatal condition that needs prompt recognition and expedited management. Clinical manifestations of BTAI are not straight forwarding and may be misdiagnosed. The grade of aortic injury is an important determinant of perioperative mortality and morbidity, as well as the indication of treatment, along with the presence of concomitant lesions of other involved organs. The mainstay of treatment nowadays for hemodynamically stable patients who survive the trauma scene is represented by delayed endovascular repair whenever anatomically and clinically feasible. Endovascular repair, in fact, is burdened by lower perioperative mortality and morbidity rates if compared to open surgical repair, but concerns remain about the need for long-term surveillance and radiation exposure in patients who are at a younger age than patients treated for the aneurysmal disease. The aim of the paper is to provide an update on the diagnostic modalities and strategies of treatment for patients affected by BTAI.
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12082903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Endovascular treatment of extracranial carotid artery stenosis using a dual-layer micromesh stents: a systematic review.

    Mazzaccaro, Daniela / Giannetta, Matteo / Fancoli, Fabiana / Righini, Paolo / Nano, Giovanni

    Expert review of medical devices

    2021  Volume 18, Issue 6, Page(s) 545–552

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Carotid Stenosis/surgery ; Cohort Studies ; Endovascular Procedures ; Humans ; Stents ; Stroke ; Treatment Outcome
    Language English
    Publishing date 2021-06-19
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2250857-0
    ISSN 1745-2422 ; 1743-4440
    ISSN (online) 1745-2422
    ISSN 1743-4440
    DOI 10.1080/17434440.2021.1927707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Role of Preoperative Ultrasound Shear-Wave Elastography and Radiofrequency-Based Arterial Wall Tracking in Assessing the Vulnerability of Carotid Plaques: Preliminary Results.

    Mazzaccaro, Daniela / Giannetta, Matteo / Fancoli, Fabiana / Matrone, Giulia / Curcio, Nicoletta / Conti, Michele / Righini, Paolo / Nano, Giovanni

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 4

    Abstract: We aimed at evaluating the ability of point shear-wave elastography (pSWE) and of a radiofrequency (RF) echo-tracking-based method in preoperatively assessing the vulnerability of the carotid plaque in patients undergoing carotid endarterectomy (CEA) for ...

    Abstract We aimed at evaluating the ability of point shear-wave elastography (pSWE) and of a radiofrequency (RF) echo-tracking-based method in preoperatively assessing the vulnerability of the carotid plaque in patients undergoing carotid endarterectomy (CEA) for significant asymptomatic stenosis. All patients who underwent CEA from 03/2021 to 03/2022 performed a preoperative pSWE and an RF echo-based wall evaluation of arterial stiffness using an Esaote MyLab ultrasound system (EsaoteTM, Genova, Italy) with dedicated software. The data derived from these evaluations (Young's modulus (YM), augmentation index (AIx), pulse-wave velocity (PWV)) were correlated with the outcome of the analysis of the plaque removed during the surgery. Data were analyzed on 63 patients (33 vulnerable and 30 stable plaques). In stable plaques, YM was significantly higher than in vulnerable plaques (49.6 + 8.1 kPa vs. 24.6 + 4.3 kPa,
    Language English
    Publishing date 2023-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13040805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Antegrade versus retrograde common iliac artery revascularization and occurrence of erectile dysfunction.

    Mazzaccaro, Daniela / Signorini, Claudia / Carmignani, Luca / Giannetta, Matteo / Vaccaro, Chiara / Fancoli, Fabiana / Guzzo, Sonia / Righini, Paolo / Vizziello, Damiano / Nano, Giovanni

    Annali italiani di chirurgia

    2022  Volume 92, Page(s) 93–101

    Abstract: Aim: To assess the effect of antegrade and retrograde common iliac artery (CIA) revascularization on erectile dysfunction (ED) using the validated International Index of Erectile Function (IIEF) questionnaire, on patients treated for chronic occlusions ... ...

    Abstract Aim: To assess the effect of antegrade and retrograde common iliac artery (CIA) revascularization on erectile dysfunction (ED) using the validated International Index of Erectile Function (IIEF) questionnaire, on patients treated for chronic occlusions of the CIA.
    Materials and methods: Clinical data of patients who were submitted either to endovascular CIA revascularization (group A) or to femoral-femoral crossover bypass (group B) due a unilateral total occlusion of the CIA between 01/2015 and 12/2019 were retrospectively analyzed. Primary outcomes included the evaluation of ED using the IIEF questionnaire, before and 30 days after the operation. A P value <0.05 was considered statistically significant.
    Results: A total of 33 patients underwent endovascular (14 patients, group A) or surgical treatment (19, group B) Before the operation, no differences were recorded in the occurrence of ED between the two groups, neither in the results of the IIEF questionnaire. After the intervention, patients of group A performed significantly better than those of group B in terms of IIEF questionnaire (18 ± 10.1 versus 12.1 ± 14.8, P=0.01). Age and COPD were negatively correlated with the preoperative results of the IIEF questionnaire (OR 0.049, 95%CI 0.02-0.05, P<0.001 and OR 0.29, 95%CI 0.01-0.56, P=0.03, respectively) and the postoperative results of the IIEF questionnaire (OR 0.02, 95% CI 0.01-0.04, P<0.001, and OR 0.46, 95% CI 0.17-0.75, P=0.001, respectively).
    Conclusions: Patients who were submitted to endovascular antegrade revascularization for occlusion of the CIA performed significantly better in terms of IIEF questionnaire than those who underwent surgical femoral-femoral crossover bypass and therefore retrograde HA revascularization.
    Key words: Common iliac artery occlusion, Erectile dysfunction, Femoro-femoral bypass, Iliac artery angioplasty, IIEF-5.
    MeSH term(s) Aorta, Abdominal ; Erectile Dysfunction/etiology ; Erectile Dysfunction/surgery ; Humans ; Iliac Artery/surgery ; Male ; Retrospective Studies ; Vascular Surgical Procedures
    Language English
    Publishing date 2022-03-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID and venous thrombosis: systematic review of literature.

    Mazzaccaro, Daniela / Giannetta, Matteo / Fancoli, Fabiana / Milani, Valentina / Modafferi, Alfredo / Malacrida, Giovanni / Righini, Paolo / Marrocco-Trischitta, Massimiliano M / Nano, Giovanni

    The Journal of cardiovascular surgery

    2021  Volume 62, Issue 6, Page(s) 548–557

    Abstract: Introduction: We aimed to review the prevalence, the risk factors and the outcomes of venous thrombosis (VT) in patients hospitalized for COronaVirus Disease 19 (COVID-19).: Evidence acquisition: Electronic bibliographic databases were searched using ...

    Abstract Introduction: We aimed to review the prevalence, the risk factors and the outcomes of venous thrombosis (VT) in patients hospitalized for COronaVirus Disease 19 (COVID-19).
    Evidence acquisition: Electronic bibliographic databases were searched using the words "COVID venous thrombosis". The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards.
    Evidence synthesis: The search of the literature retrieved 877 results. After assessment of full texts, 69 papers were included in the qualitative analysis and 23 of them in the quantitative evaluation. The analyzed studies included a total of 106,838 patients hospitalized for COVID-19 from January to December 2020. The pooled reported prevalence rate of VT was in median 16.7% (IQR 5.8-30%), being higher in ICU patients (60.8-85.4%). VT events were reported in about 75% of cases in the popliteal and calf veins. Signs and symptoms were present in 6.1% of cases. At quantitative evaluation, older age, D-dimer and obesity increased the odds to experience a VT (OR=3.54, 95% CI 0.65-6.43, P=0.01; OR=956.86, 95% CI 225.67-1668.05, P=0.01; OR=1.42, 95% CI 1.01-1.99, P=0.03 respectively). Female sex seemed to be protective against the odds of VT (OR=0.77, 95% CI 0.63-0.93, P=0.007).
    Conclusions: Among patients hospitalized for COVID-19, VT is a relatively common finding, with higher prevalence rates in ICU patients. VT occurs mostly in the distal regions of the lower limb and is asymptomatic in most cases. Older age, obesity and higher D-dimer values on admission increased the odds of VT, while female sex was protective against the odds of VT.
    MeSH term(s) Age Factors ; Anticoagulants/therapeutic use ; Biomarkers/blood ; Blood Coagulation/drug effects ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/therapy ; Fibrin Fibrinogen Degradation Products/metabolism ; Hospitalization ; Humans ; Obesity/epidemiology ; Prevalence ; Prognosis ; Risk Assessment ; Risk Factors ; Sex Factors ; Venous Thrombosis/blood ; Venous Thrombosis/diagnosis ; Venous Thrombosis/drug therapy ; Venous Thrombosis/epidemiology
    Chemical Substances Anticoagulants ; Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Language English
    Publishing date 2021-09-14
    Publishing country Italy
    Document type Journal Article ; Systematic Review
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.21.12022-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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