LIVIVO - Search results -

Search results

Result 1 - 10 of total 384

Search options

Book: Special issue: Landscape patterns and ecosystem processes of the Mongolian Plateau

Fang, Jingyun / Bai, Yongfei

(Landscape ecology ; Volume 30, No. 9 (November 2015))

2015

Title variant	Landscape patterns and ecosystem processes of the Mongolian Plateau
Author's details	guest editors: Jingyun Fang, Yongfei Bai
Series title	Landscape ecology ; Volume 30, No. 9 (November 2015)
Collection
Language	English
Size	Seite 1573 - 1803, Illustrationen
Publisher	Springer
Publishing place	Heidelberg
Publishing country	Germany
Document type	Book
HBZ-ID	HT018854894
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
Z 5101 (30,9)	available for loan (reading room)	Freihandmagazin (U1)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Protective effect and mechanism of γ-secretase inhibitor on myocardial injury in sepsis rats.

Fang, Jingyun / Zhou, Yuming

American journal of translational research

2023 Volume 15, Issue 2, Page(s) 1017–1025

Abstract: Objective: This study aimed to investigate the mechanism of γ-secretase inhibitor (GSI) in myocardial repair in septic rats.: Methods: Thirty-six healthy male Wistar rats were randomly and equally divided into control groups, model group and ... ...

Abstract	Objective: This study aimed to investigate the mechanism of γ-secretase inhibitor (GSI) in myocardial repair in septic rats. Methods: Thirty-six healthy male Wistar rats were randomly and equally divided into control groups, model group and intervention group. The model group and the intervention group were treated with ligation of cecum and perforation to build sepsis model, and the intervention group received intraperitoneal injection of GSI II (DAPT). Serum levels of Troponin T (cTnT), creatine kinase isoenzyme (CK-MB) and interleukin-17 were measured by ELISA. The Th17 cell percentage in peripheral blood mononuclear cells in CD4 Results: The cTnT, CK-MB, Th17 and Th17/CD4 Conclusion: γ secretase inhibitors have clearly protective effects on cardiomyocytes, and the mechanism may be associated with Notch blocking and RORγt expression, which inhibit immune damage induced by abnormal activation of Th17.
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: γ-Secretase inhibitor alleviates lipopolysaccharide-induced myocardial injury through regulating JAK2/STAT3 signaling.

Fang, Jingyun / Guan, Huan

Environmental toxicology

2023 Volume 39, Issue 1, Page(s) 135–147

Abstract: Background: Septic myocardial injury is one of the most life-threatening organ dysfunction. The γ-secretase-based approaches have been developed as potential strategies for diverse diseases management. Unfortunately, the role of γ-secretase inhibitor in ...

Abstract	Background: Septic myocardial injury is one of the most life-threatening organ dysfunction. The γ-secretase-based approaches have been developed as potential strategies for diverse diseases management. Unfortunately, the role of γ-secretase inhibitor in septic myocardial injury is unclarified. The present study aims to investigate the effect of γ-secretase inhibitor in septic myocardial injury and reveal its mechanism. Methods: The mouse model of septic myocardial injury was established by intraperitoneally injection of lipopolysaccharide (LPS), and γ-secretase inhibitor MW167 was applied in this model. RNA-sequencing analysis and further bioinformatics analyses were used to screen differential expressed genes (DEGs) and potentially enriched pathways between LPS and LPS + MW167 mice. Pathological examination was performed using haematoxylin and eosin (HE) staining. SD-1029 was used to block JAK2/STAT3 signaling in H9C2 cells and western blot analysis quantified JAK2/STAT3-related proteins. Results: LPS induced myocardial injury accompanied with significant inflammatory infiltration and more apoptotic cells. Transcriptome sequencing screened 36 DEGs and bioinformatics identified JAK2/STAT3 signaling pathway was significantly enriched. Further in vitro experiments showed that γ-secretase inhibitor MW167 activated JAK2/STAT3 pathway. Additionally, MW167 restored cell viability, decreased myocardial injury markers including cardiac troponin I (cTnI) and brain natriuretic peptide (BNP), inhibited pro-inflammatory cytokines such as interleukin (IL)-1β and tumor necrosis factor-α (TNF-α) and reduced nitric oxide (NO), cyclooxygenase-2 (COX2) and inducible nitric oxide synthase (iNOS) release. Application of SD-1029 reversely deteriorated LPS-induced myocardial injury and inflammatory response in γ-secretase inhibitor-treated myocardial cells. Conclusion: The results demonstrate that γ-secretase inhibitor alleviates septic myocardial injury via activating JAK2/STAT3 signaling, and provide novel therapeutic direction for septic myocardial injury.
MeSH term(s)	Mice ; Animals ; Lipopolysaccharides/toxicity ; Amyloid Precursor Protein Secretases/metabolism ; Signal Transduction ; Cytokines/metabolism ; Myocardium/metabolism ; STAT3 Transcription Factor/metabolism ; Janus Kinase 2/metabolism
Chemical Substances	Lipopolysaccharides ; Amyloid Precursor Protein Secretases (EC 3.4.-) ; Cytokines ; STAT3 Transcription Factor ; Janus Kinase 2 (EC 2.7.10.2)
Language	English
Publishing date	2023-09-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	1463449-1
ISSN	1522-7278 ; 1520-4081
ISSN (online)	1522-7278
ISSN	1520-4081
DOI	10.1002/tox.23962
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2676: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Effect of various doses of rosuvastatin in the treatment of elderly patients with unstable angina pectoris.

Fang, Jingyun / Zhang, Xueli

American journal of translational research

2022 Volume 14, Issue 1, Page(s) 594–602

Abstract: Objectives: This prospective study aimed to explore the effects of various doses of rosuvastatin on the hemodynamic changes, highly sensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels in elderly patients with unstable angina pectoris.!# ...

Abstract	Objectives: This prospective study aimed to explore the effects of various doses of rosuvastatin on the hemodynamic changes, highly sensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels in elderly patients with unstable angina pectoris. Methods: One-hundred and six elderly patients with unstable angina pectoris were enrolled and divided into group A (n=55) and group B (n=51). Under the same treatment for angina pectoris, patients in groups A and B were administered with 5 mg and 10 mg of rosuvastatin orally once every night, respectively. The two groups were compared in terms of hemorheology, coagulation indices and immune reaction (serum hs-CRP and IL-6 levels), changes of clinical indices, electrocardiograph (ECG), therapeutic effect, and incidence of adverse reactions. Serum hs-CRP and IL-6 levels were detected by ELISA method, and their correlation was analyzed by Pearson method. Results: Whole blood viscosity at high cut (BVH), whole blood viscosity at low cut (BVL), plasma viscosity (PV), and erythrocyte sedimentation rate (ESR), immunoglobulin index, and the hs-CRP and IL-6 levels decreased in both groups after treatment and were lower in group B than in group A ( Conclusions: The optimal efficacy of rosuvastatin at 10 mg/day was higher than that of rosuvastatin at 5 mg/day.
Language	English
Publishing date	2022-01-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Above‐ and belowground net‐primary productivity: A field‐based global database of grasslands

Sun, Yuanfeng / Chang, Jinfeng / Fang, Jingyun

Ecology. 2023 Feb., v. 104, no. 2 p.e3904-

2023

Abstract: Net primary productivity (NPP) over global grasslands is crucial for understanding the terrestrial carbon cycling and for the assessments of wild herbivores food security. During the past few decades, numerous field investigations have been conducted to ... ...

Abstract	Net primary productivity (NPP) over global grasslands is crucial for understanding the terrestrial carbon cycling and for the assessments of wild herbivores food security. During the past few decades, numerous field investigations have been conducted to estimate grassland NPP since the measuring criterion released by the International Biological Program. However, a comprehensive NPP database, particularly for belowground NPP (BNPP), in global grasslands is rare to date. Here, field NPP measurements from 438 publications (1957–2018) in global grasslands were collected, critically filtered, and incorporated in a comprehensive global database with observations for aboveground NPP (ANPP), BNPP, total NPP (TNPP), and BNPP fraction (fBNPP). Associated information on geographical locations, climatic records, grassland types, land use patterns, manipulations subjected to manipulative experiments, sampling year of study sites, as well as NPP measurement methods are also documented. This database included 2985 entries from 1785 study sites. Among them, 806 entries contained paired data of ANPP and BNPP, resulting in the 806 fBNPP data. The study sites encompassed global grasslands with latitudinal range of 54.5° S~78.9° N, longitudinal range of 157.4° W~175.8° E, and altitudes from 0 to 5168 m above sea level, covering broad climatic gradients (−17.6 to 28.8°C in mean annual temperature and 63–2052 mm in mean annual precipitation). This global database is the world's largest paired data of ANPP and BNPP field measurements in grasslands. It can be used to study the spatio‐temporal patterns of NPP and its allocation, evaluate the responses of above‐ and below‐ground carbon components to future global changes, and validate the NPP estimation by empirical or process‐based models in global grasslands. The database can be freely used for noncommercial applications. We kindly request users cite this data paper when using the database, respecting all the hard work during data compilation.
Keywords	atmospheric precipitation ; carbon ; databases ; food security ; grasslands ; land use ; net primary productivity ; temperature
Language	English
Dates of publication	2023-02
Publishing place	John Wiley & Sons, Inc.
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	1797-8
ISSN	0012-9658
ISSN	0012-9658
DOI	10.1002/ecy.3904
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 4' 49/37: Show issues
Z 7543: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: A meta-analysis of the clinical efficacy of rhBNP in treating patients with acute myocardial infarction and heart failure.

Fang, Jingyun / Zeng, Weilan

American journal of translational research

2021 Volume 13, Issue 4, Page(s) 2410–2421

Abstract: Objective: To explore the clinical efficacy of rhBNP in patients with acute myocardial infarction (AMI) and heart failure (HF).: Methods: A systematic review and a meta-analysis were performed using the : Results: A total of nine, clinical, ... ...

Abstract	Objective: To explore the clinical efficacy of rhBNP in patients with acute myocardial infarction (AMI) and heart failure (HF). Methods: A systematic review and a meta-analysis were performed using the Results: A total of nine, clinical, randomized, controlled studies were included. The effective rate in the rhBNP group was significantly higher than it was in the control group (Z = 9.50, Conclusion: The meta-analysis suggests that, compared with the conventional treatment of patients with AMI and HF, rhBNP can markedly improve the clinical efficacy and myocardial functions and shorten the hospital stays, without elevating the rate of adverse reactions, such as hypotension, headaches, low heart rate, and renal insufficiency.
Language	English
Publishing date	2021-04-15
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Comprehensive Therapeutic Efficacy Analysis of Intravenous Immunoglobulin in Treating Sepsis-induced Coagulopathy: A Single-Center, Retrospective Observational Study.

Fang, Jingyun / Huang, Peng / Cui, Wanfu / Lin, Ye / Rong, Dan / Li, Xu

Shock (Augusta, Ga.)

2024

Abstract: Objectives: To investigate the efficacy of intravenous immunoglobulin (IVIg) in treating sepsis-induced coagulopathy (SIC).: Methods: A retrospective controlled analysis was conducted on 230 patients with SIC at Ganzhou People's Hospital from January ...

Abstract	Objectives: To investigate the efficacy of intravenous immunoglobulin (IVIg) in treating sepsis-induced coagulopathy (SIC). Methods: A retrospective controlled analysis was conducted on 230 patients with SIC at Ganzhou People's Hospital from January 2016 to December 2022. All patients were screened using propensity score matching and treated according to the SSC2016 guidelines. Compared to the control group (n = 115), patients in the test group (n = 115) received IVIg (200 mg/kg.d) for 3 consecutive days post-admission. The rating scales, coagulation function, survival, and treatment duration were evaluated. Results: On day 3 of treatment, both groups exhibited reduced PLT and TEG-MA levels, with the control group showing a more significant decrease (P < 0.05). By the 5th day, these levels had recovered in both groups. However, the test group experienced a significant increase by day 7 (P < 0.05). Coagulation factors II and X began to increase on day 3, and normalization was significantly faster in the test group on day 5 (P < 0.05). The levels of PT, INR, APTT, D-dimer, FIB, FDP, TEG-R, and TEG-K exhibited a notable decline on day 3 and demonstrated significantly faster recovery on day 5 in the test group (P < 0.05). Additionally, both groups showed a reduction in APACHE II, SOFA, DIC, and LAC levels on day 3, but the test group's scores decreased significantly more by day 7 (P < 0.05). Within the test group, WBC count, CRP, PCT, IL-6, and Tmax levels were lower (P < 0.05). Furthermore, the test group demonstrated shorter duration for ICU stay, mechanical ventilation, and CRRT (P < 0.05). No significant differences were observed in the duration of fever or vasoactive drug use between the groups. However, the log-rank method indicated a higher 28-day survival rate in the test group (P < 0.05). Conclusion: IVIg can successfully increase platelet count and coagulation factors, correct coagulation disorders, enhance organ function, and reduce 28-day mortality in patients with SIC.
Language	English
Publishing date	2024-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1185432-7
ISSN	1540-0514 ; 1073-2322
ISSN (online)	1540-0514
ISSN	1073-2322
DOI	10.1097/SHK.0000000000002336
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3985: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Reinvestigation on High-Valent Cobalt for the Degradation of Micropollutants in the Co(II)/Peroxymonosulfate System: Roles of Co(III).

Cao, Yilong / Wang, Zhen / He, Shaoxiong / Shi, Lixuan / Guo, Kaiheng / Fang, Jingyun

Environmental science & technology

2024

Abstract: Recently, reactive cobalt (Co) species, including Co(IV)-oxo and Co(II)- ... ...

Abstract	Recently, reactive cobalt (Co) species, including Co(IV)-oxo and Co(II)-OOSO
Language	English
Publishing date	2024-02-09
Publishing country	United States
Document type	Journal Article
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.3c10062
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Visible light-driven g-C3N4 peroxymonosulfate activation process for carbamazepine degradation: Activation mechanism and matrix effects

Cheng, Zihang / Ling, Li / Fang, Jingyun / Shang, Chii

Chemosphere. 2022 Jan., v. 286

2022

Abstract: In this study, g-C₃N₄ with a high portion of tri-s-triazine groups was synthesized to activate peroxymonosulfate (PMS) under visible light irradiation, termed as Vis/g-C₃N₄/PMS process, to degrade one frequently detected recalcitrant micropollutant ... ...

Abstract	In this study, g-C₃N₄ with a high portion of tri-s-triazine groups was synthesized to activate peroxymonosulfate (PMS) under visible light irradiation, termed as Vis/g-C₃N₄/PMS process, to degrade one frequently detected recalcitrant micropollutant carbamazepine (CBZ). The Vis/g-C₃N₄/PMS process increased pseudo first-order degradation rate constant of CBZ by 2 times compared with that in the absence of PMS. The enhanced CBZ degradation was because of the production of HO and SO₄– from the PMS activation, but not the enhanced charge separation of g-C₃N₄ due to the presence of PMS. The Vis/g-C₃N₄/PMS process is insensitive to dissolved oxygen, chloride and bicarbonate concentrations, effective over a wide pH range from 6.0 to 10.0, and less affected by high concentrations of natural organic matter compared with the UV/chlorine and UV/TiO₂ processes. In addition, photocatalytic activity of g-C₃N₄ remains stable over 5-cycle of reuse. These features make the process practically relevant and implementable in degrading micropollutants in drinking water, treated wastewater, surface water, groundwater, etc., using more efficient visible light LEDs or even sunlight.
Keywords	bicarbonates ; chlorides ; chlorine ; dissolved oxygen ; groundwater ; irradiation ; light ; organic matter ; pH ; photocatalysis ; pollutants ; solar radiation ; surface water ; wastewater
Language	English
Dates of publication	2022-01
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2021.131906
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2540: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Thermal dissipation of the quantum spin Hall edge states in HgTe/CdTe quantum well.

Fang, Jing-Yun / Zhuang, Yu-Chen / Guo, Ai-Min / Sun, Qing-Feng

Journal of physics. Condensed matter : an Institute of Physics journal

2023 Volume 35, Issue 50

Abstract: Quantum spin Hall effect is characterized by topologically protected helical edge states. Here we study the thermal dissipation of helical edge states by considering two types of dissipation sources. The results show that the helical edge states are ... ...

Abstract	Quantum spin Hall effect is characterized by topologically protected helical edge states. Here we study the thermal dissipation of helical edge states by considering two types of dissipation sources. The results show that the helical edge states are dissipationless for normal dissipation sources with or without Rashba spin-orbit coupling in the system, but they are dissipative for spin dissipation sources. Further studies on the energy distribution show that electrons with spin-up and spin-down are both in their own equilibrium without dissipation sources. Spin dissipation sources can couple the two subsystems together to induce voltage drop and non-equilibrium distribution, leading to thermal dissipation, while normal dissipation sources cannot. With the increase of thermal dissipation, the subsystems of electrons with spin-up and spin-down evolve from non-equilibrium finally to mutual equilibrium. In addition, the effects of disorder on thermal dissipation are also discussed. Our work provides clues to reduce thermal dissipation in the quantum spin Hall systems.
Language	English
Publishing date	2023-09-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1472968-4
ISSN	1361-648X ; 0953-8984
ISSN (online)	1361-648X
ISSN	0953-8984
DOI	10.1088/1361-648X/acf826
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito