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  1. Article ; Online: Gift-giving intentions in pan-entertainment live streaming

    Zhi Zhang / Fang Liu

    PLoS ONE, Vol 19, Iss

    Based on social exchange theory

    2024  Volume 1

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Gift-giving intentions in pan-entertainment live streaming

    Zhi Zhang / Fang Liu

    PLoS ONE, Vol 19, Iss 1, p e

    Based on social exchange theory.

    2024  Volume 0296908

    Abstract: Pan-entertainment live streaming combines video with two-way communication and real-time viewer participation, allowing viewers to send virtual gifts to their favorite streamers. Drawing on social exchange theory, this study investigates the factors that ...

    Abstract Pan-entertainment live streaming combines video with two-way communication and real-time viewer participation, allowing viewers to send virtual gifts to their favorite streamers. Drawing on social exchange theory, this study investigates the factors that influence viewers' gift-giving intentions in live streaming from the perspectives of both viewers and streamers. It also explores the moderating role of streamers' deceptive self-presentation. The theoretical framework is tested using AMOS and PROCESS Macro based on survey responses collected from 331 TikTok users in China. The results suggest that streamers' attractiveness, expertise, parasocial interaction, and the viewers' deceptive self-presentation significantly affect viewers' gift-giving intention, and that streamers' deceptive self-representation moderates the relationship between attractiveness, expertise, parasocial inter-action and the viewer's consumer intention. These findings contribute to social exchange theory by highlighting the importance of streamers' deceptive self-presentation in moderating the effects of attractiveness, expertise, parasocial interaction, and the viewer's deceptive self-presentation on the viewer's gift-giving intention.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Investigating the role and mechanisms of tricin in ischemia-reperfusion-induced myocardial injury in LDLr -/- MICE.

    Feilong Sun, - / Xue Ma, - / Yu Wang, - / Fang Liu, -

    Pakistan journal of pharmaceutical sciences

    2023  Volume 36, Issue 4, Page(s) 1045–1051

    Abstract: The objective of this study was to investigate the function and biological mechanisms of tricin in in-vivo damage to the myocardium produced by ischemia-reperfusion in LDLr -/- mice. The hypercholesterolemia animal model employed was male LDLr -/- mice. ... ...

    Abstract The objective of this study was to investigate the function and biological mechanisms of tricin in in-vivo damage to the myocardium produced by ischemia-reperfusion in LDLr -/- mice. The hypercholesterolemia animal model employed was male LDLr -/- mice. Coronary artery occlusion in mice resulted in the detection of oxidative stress and inflammatory pathology. In mice with coronary artery blockage, tricin reduced oxidative burden in the cardiac tissue and inflammatory mediators. Additionally, the ST segment of the animals receiving tricin was resumed. Tricine could dramatically lessen myocardial damage, according to pathological examination and triphenyltetrazolium chloride (TTC) staining. As a result of the research described above, the protective effects of tricin on myocardial injury have been explored, and the influence of inflammation and oxidative assaults in the ischemia-reperfusion injury (I/R) model of the heart has been demonstrated.
    MeSH term(s) Male ; Animals ; Myocardium ; Heart ; Reperfusion Injury ; Reperfusion
    Chemical Substances tricin (D51JZL38TQ)
    Language English
    Publishing date 2023-08-21
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Learning to play

    Shuangyuan Cao / Fang Liu

    Heliyon, Vol 8, Iss 11, Pp e11482- (2022)

    understanding in-game tutorials with a pilot study on implicit tutorials

    2022  

    Abstract: Tutorials are essential strategies used by game designers to improve video games' playability. The concept of “learning to play” exemplified by game tutorials also seems potentially related to game-based learning, but studies on game tutorials still ... ...

    Abstract Tutorials are essential strategies used by game designers to improve video games' playability. The concept of “learning to play” exemplified by game tutorials also seems potentially related to game-based learning, but studies on game tutorials still appear scant. In order to support more in-depth researching on in-game tutorials and contribute to the current understanding of players' gameplay learning, this paper performed a literature review on research of game tutorials and revealed five commonly reported features of in-game tutorials. First, tutorials are typically considered more significant for games with complex gameplay. Second, players' gaming proficiency should be consulted when studying in-game tutorials. Third, the tutorials may be more effective when players can practice on their own and receive timely feedback. Fourth, providing players with just-in-time access to tutorials was thought to have a positive effect on their learning of the gameplay. Finally, the research in this area had been reported as deficient until 2017. Based on the literature review, a pilot study on implicit game tutorials was conducted to explore a more effective form of in-game tutorials. Using a designed questionnaire, the pilot study performed a quantitative analysis on recruited players’ feedback and in-game performance and tested the results against five hypotheses established upon the literature review. It suggested that providing players with implicit guidance and gamified instructive elements in the tutorial section can improve their in-game perceptions, and implicit tutorials are especially beneficial for players experienced in gaming. This study extended the previous studies on game tutorials and may contribute to the follow-up studies on game tutorials.
    Keywords Game studies ; Game design ; In-game tutorial ; Human-computer interaction ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 700
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: COVID-19 sentiment analysis using college subreddit data.

    Tian Yan / Fang Liu

    PLoS ONE, Vol 17, Iss 11, p e

    2022  Volume 0275862

    Abstract: Background The COVID-19 pandemic has affected our society and human well-being in various ways. In this study, we investigate how the pandemic has influenced people's emotions and psychological states compared to a pre-pandemic period using real-world ... ...

    Abstract Background The COVID-19 pandemic has affected our society and human well-being in various ways. In this study, we investigate how the pandemic has influenced people's emotions and psychological states compared to a pre-pandemic period using real-world data from social media. Method We collected Reddit social media data from 2019 (pre-pandemic) and 2020 (pandemic) from the subreddits communities associated with eight universities. We applied the pre-trained Robustly Optimized BERT pre-training approach (RoBERTa) to learn text embedding from the Reddit messages, and leveraged the relational information among posted messages to train a graph attention network (GAT) for sentiment classification. Finally, we applied model stacking to combine the prediction probabilities from RoBERTa and GAT to yield the final classification on sentiment. With the model-predicted sentiment labels on the collected data, we used a generalized linear mixed-effects model to estimate the effects of pandemic and in-person teaching during the pandemic on sentiment. Results The results suggest that the odds of negative sentiments in 2020 (pandemic) were 25.7% higher than the odds in 2019 (pre-pandemic) with a p-value < 0.001; and the odds of negative sentiments associated in-person learning were 48.3% higher than with remote learning in 2020 with a p-value of 0.029. Conclusions Our study results are consistent with the findings in the literature on the negative impacts of the pandemic on people's emotions and psychological states. Our study contributes to the growing real-world evidence on the various negative impacts of the pandemic on our society; it also provides a good example of using both ML techniques and statistical modeling and inference to make better use of real-world data.
    Keywords Medicine ; R ; Science ; Q
    Subject code 370
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Quantitative Evaluation of Waste Separation Management Policies in the Yangtze River Delta Based on the PMC Index Model

    Fang Liu / Zhi Liu

    International Journal of Environmental Research and Public Health, Vol 19, Iss 3815, p

    2022  Volume 3815

    Abstract: Numerous policies have been formulated and implemented to strengthen waste separation management activities in many countries. Waste separation management policies (WSMPs) must be evaluated as the precondition for reducing deviations from policy ... ...

    Abstract Numerous policies have been formulated and implemented to strengthen waste separation management activities in many countries. Waste separation management policies (WSMPs) must be evaluated as the precondition for reducing deviations from policy implementation and improving waste separation performance. Based on text mining technology and the construction of a policy modeling consistency (PMC) index model, we conducted a quantitative evaluation of 22 WSMPs issued by central governmental departments and provinces in the Yangtze River Delta, China from 2013 to 2021 and analyzed their optimization paths. The results suggest that the PMC index of the selected WSMPs has an upward trend. The average PMC index of 22 WSMPs was 6.906, indicating good quality in the policy texts. The PMC index identified seven, nine, five, and one of the policies as being perfect, excellent, good, and acceptable, respectively. The characteristics of WSMPs were further illustrated through PMC surface charts. Based on this, optimization paths for WSMPs with lower PMC indexes are proposed, which indicate that existing WSMPs have great potential for optimization in terms of harsher constraint regulations, context-appropriate incentives, and cultivation of market participants. Finally, this study provides a beneficial reference for similar cities or countries to improve their performance in the management of waste separation and environmental protection.
    Keywords waste separation management ; PMC index model ; quantitative evaluation ; optimization path ; Yangtze River Delta ; Medicine ; R
    Subject code 710
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Real-world data

    Fang Liu / Demosthenes Panagiotakos

    BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-

    a brief review of the methods, applications, challenges and opportunities

    2022  Volume 10

    Abstract: Abstract Background The increased adoption of the internet, social media, wearable devices, e-health services, and other technology-driven services in medicine and healthcare has led to the rapid generation of various types of digital data, providing a ... ...

    Abstract Abstract Background The increased adoption of the internet, social media, wearable devices, e-health services, and other technology-driven services in medicine and healthcare has led to the rapid generation of various types of digital data, providing a valuable data source beyond the confines of traditional clinical trials, epidemiological studies, and lab-based experiments. Methods We provide a brief overview on the type and sources of real-world data and the common models and approaches to utilize and analyze real-world data. We discuss the challenges and opportunities of using real-world data for evidence-based decision making This review does not aim to be comprehensive or cover all aspects of the intriguing topic on RWD (from both the research and practical perspectives) but serves as a primer and provides useful sources for readers who interested in this topic. Results and Conclusions Real-world hold great potential for generating real-world evidence for designing and conducting confirmatory trials and answering questions that may not be addressed otherwise. The voluminosity and complexity of real-world data also call for development of more appropriate, sophisticated, and innovative data processing and analysis techniques while maintaining scientific rigor in research findings, and attentions to data ethics to harness the power of real-world data.
    Keywords Real-world data (RWD) ; Real-world evidence (RWE) ; Electronic health records ; Machine learning ; Artificial intelligence ; Causal inference ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Differential Correlation of Transcriptome Data Reveals Gene Pairs and Pathways Involved in Treatment of Citrobacter rodentium Infection with Bioactive Punicalagin

    Damarius S. Fleming / Fang Liu / Robert W. Li

    Molecules, Vol 28, Iss 21, p

    2023  Volume 7369

    Abstract: This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate ...

    Abstract This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate the ability of the pomegranate extract punicalagin against intracellular parasites. The study compared transcriptomic reads of two distinct conditions. Condition A was treated with punicalagin (PA) and challenged with Citrobacter rodentium , while condition B (CM) consisted of a group that was challenged and given mock treatment of PBS. To understand the effect of punicalagin on transcriptomic changes between conditions, a differential correlation analysis was conducted. The analysis examined the regulatory connections of genes expressed between different treatment conditions by statistically querying the relationship between correlated gene pairs and modules in differing conditions. The results indicated that punicalagin treatment had strong positive correlations with the over-enriched gene ontology (GO) terms related to oxidoreductase activity and lipid metabolism. However, the GO terms for immune and cytokine responses were strongly correlated with no punicalagin treatment. The results matched previous studies that showed punicalagin to have potent antioxidant and antiparasitic effects when used to treat parasitic infections in mice and livestock. Overall, the results indicated that punicalagin enhanced the effect of tissue-resident genes.
    Keywords parasite ; citrobacter ; bioactive compound ; differential correlation ; Organic chemistry ; QD241-441
    Subject code 572
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Factors associated with caregiver burden among family caregivers of children with cerebral palsy

    Fang Liu / Qiao Shen / Miao Huang / Hengyu Zhou

    BMJ Open, Vol 13, Iss

    a systematic review

    2023  Volume 4

    Abstract: Objectives To identify caregiver and children factors associated with caregiver burden on primary caregivers of children with cerebral palsy (CP).Design Systematic reviewData sources Seven electronic databases, including PubMed, Cochrane Library, Scopus, ...

    Abstract Objectives To identify caregiver and children factors associated with caregiver burden on primary caregivers of children with cerebral palsy (CP).Design Systematic reviewData sources Seven electronic databases, including PubMed, Cochrane Library, Scopus, PsycINFO, Web of Science, CINAHL and Embase, were systematically searched up to 1 February 2023.Eligibility criteria Original observational studies reporting caregiver burden and related factors among caregivers of children with CP.Data abstraction and synthesis Two reviewers independently screened results and assessed the quality of studies. Title, abstract, full-text screening and data abstraction were done independently by two reviewers. Risk of bias was assessed using the JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies. The quality of evidence for factors was rated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.Results 16 articles were included in the review. All studies were cross-sectional and examined caregiver-reported burden measures. The Zarit Burden Interview was the most commonly used questionnaire. Depression of caregiver and severity of illness in children with CP were moderate quality of evidence for factors contributing to caregiver burden.Conclusions Higher caregiver burden is associated with more depressive feelings and worse life quality of the caregiver, and with more severe physical disability of the children. Future studies should focus on high-quality longitudinal research and appropriate assistance to reduce caregiver burden and improve the quality of caregiving for children with CP.PROSPERO registration number CRD42021268284.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A Study on the Sintering Mechanism of High-Strength Light Bricks Manufactured from Coal Gasification Slag

    Fang Liu / Guofeng Niu / Wentao Guo

    Sustainability, Vol 15, Iss 4860, p

    2023  Volume 4860

    Abstract: In this article, we report a way to produce sintered bricks from industrial coal gasification slag. Subsequently, we studied the impact of the addition of coal gasification slag and heat treatment on the density and compression strength of sintered ... ...

    Abstract In this article, we report a way to produce sintered bricks from industrial coal gasification slag. Subsequently, we studied the impact of the addition of coal gasification slag and heat treatment on the density and compression strength of sintered materials with controlled variables. In addition, we implemented thermogravimetric analysis-differential scanning calorimetry (TG-DSC), an X-ray powder diffractometer (XRD), and a scanning electron microscope (SEM), as well as optical and thermal measurement devices, to analyze the microscopic structures of sintered materials; this revealed the action mechanism of coal gasification slag on the microscopic morphology and performance of sintered bricks. The volumetric density and compression strength of the sintered bricks were found to be negatively correlated with the amount of coal gasification slag introduced, but positively correlated with the sintering temperature. When the firing temperature was 1150 °C and the addition amount of coal gasification slag was 45%, the sintered brick products, with a predominant crystalline phase of anorthites, could achieve a density of 1.5 g/cm 3 and a compression strength of 30 MPa; this met the requirements of the China National Standard GB/T 5101-2017 for MU30 bricks. This report may help with the implementation of coal gasification slag.
    Keywords coal gasification slag ; sintered brick ; density ; compression strength ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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