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  1. Book ; Online: Surface Plasmon Resonance for Biosensing

    Fantoni, Alessandro

    2022  

    Keywords History of engineering & technology ; gold nanorods ; silica coating ; localized surface plasmon resonance (LSPR) ; surface functionalization ; SPR biosensor ; enzyme ; laccase ; chlorophene ; emerging pollutant ; water sample ; plasmonic nanowires ; molecular sensing ; surface-enhanced Raman spectroscopy ; porous alumina ; TREM2 sensors ; Alzheimer's disease ; plasmonic interferometry ; optical biosensor ; surface plasmon resonance ; olfactory sensors ; electronic noses ; volatile organic compounds ; odorants ; SPR ; cell-based assay ; viral growth kinetics ; human coronavirus ; hydroxychloroquine ; protease ; caspase ; avidin-biotin interaction ; biosensors ; AuNPs ; metal-graphene hybrid ; simulations ; Mie theory ; African swine fever virus (ASFV) ; loop-mediated isothermal amplification (LAMP) ; surface plasmon resonance (SPR) ; fluorescence detection ; SERS analysis ; plasmonic metal nanoparticles ; hotspots ; hybrid materials
    Language English
    Size 1 electronic resource (224 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030381109
    ISBN 9783036546582 ; 3036546588
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review.

    Serafinelli, Caterina / Fantoni, Alessandro / Alegria, Elisabete C B A / Vieira, Manuela

    Biosensors

    2022  Volume 12, Issue 4

    Abstract: In SERS analysis, the specificity of molecular fingerprints is combined with potential single-molecule sensitivity so that is an attractive tool to detect molecules in trace amounts. Although several substrates have been widely used from early on, there ... ...

    Abstract In SERS analysis, the specificity of molecular fingerprints is combined with potential single-molecule sensitivity so that is an attractive tool to detect molecules in trace amounts. Although several substrates have been widely used from early on, there are still some problems such as the difficulties to bind some molecules to the substrate. With the development of nanotechnology, an increasing interest has been focused on plasmonic metal nanoparticles hybridized with (2D) nanomaterials due to their unique properties. More frequently, the excellent properties of the hybrids compounds have been used to improve the drawbacks of the SERS platforms in order to create a system with outstanding properties. In this review, the physics and working principles of SERS will be provided along with the properties of differently shaped metal nanoparticles. After that, an overview on how the hybrid compounds can be engineered to obtain the SERS platform with unique properties will be given.
    MeSH term(s) Gold/chemistry ; Metal Nanoparticles/chemistry ; Nanostructures/chemistry ; Nanotechnology ; Spectrum Analysis, Raman
    Chemical Substances Gold (7440-57-5)
    Language English
    Publishing date 2022-04-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12040225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors-A Comparative Study.

    Carvalho, Ana P G / Alegria, Elisabete C B A / Fantoni, Alessandro / Ferraria, Ana M / do Rego, Ana M Botelho / Ribeiro, Ana P C

    Biosensors

    2022  Volume 12, Issue 3

    Abstract: Aiming to develop a nanoparticle-based optical biosensor using gold nanoparticles (AuNPs) synthesized using green methods and supported by carbon-based nanomaterials, we studied the role of carbon derivatives in promoting AuNPs localized surface plasmon ... ...

    Abstract Aiming to develop a nanoparticle-based optical biosensor using gold nanoparticles (AuNPs) synthesized using green methods and supported by carbon-based nanomaterials, we studied the role of carbon derivatives in promoting AuNPs localized surface plasmon resonance (LSPR), as well as their morphology, dispersion, and stability. Carbon derivatives are expected to work as immobilization platforms for AuNPs, improving their analytical performance. Gold nanoparticles (AuNPs) were prepared using an eco-friendly approach in a single step by reduction of HAuCl
    MeSH term(s) Biosensing Techniques/methods ; Gold/chemistry ; Graphite/chemistry ; Metal Nanoparticles/chemistry
    Chemical Substances graphene oxide ; Gold (7440-57-5) ; Graphite (7782-42-5)
    Language English
    Publishing date 2022-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12030163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Hypogonadism and sexual function in men affected by adrenocortical carcinoma under mitotane therapy.

    Canu, Letizia / Sparano, Clotilde / Naletto, Lara / De Filpo, Giuseppina / Cantini, Giulia / Rapizzi, Elena / Martinelli, Serena / Ercolino, Tonino / Cioppi, Francesca / Fantoni, Alessandro / Zanatta, Lorenzo / Terreni, Alessandro / Mannelli, Massimo / Luconi, Michaela / Maggi, Mario / Lotti, Francesco

    Frontiers in endocrinology

    2024  Volume 14, Page(s) 1320722

    Abstract: Purpose: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC male patients under adjuvant mitotane therapy (AMT) frequently develop hypogonadism, however sexual function has never been assessed in this setting. The aim of this ... ...

    Abstract Purpose: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC male patients under adjuvant mitotane therapy (AMT) frequently develop hypogonadism, however sexual function has never been assessed in this setting. The aim of this retrospective study was to evaluate in AMT treated ACC patients the changes in Luteinizing hormone (LH), Sex Hormone Binding Globulin (SHBG), total testosterone (TT) and calculated free testosterone (cFT), the prevalence and type of hypogonadism and sexual function, the latter before and after androgen replacement therapy (ART).
    Methods: LH, SHBG, TT and cFT were assessed in ten ACC patients at baseline (T0) and six (T1), twelve (T2), and eighteen (T3) months after AMT. At T3, ART was initiated in eight hypogonadal patients, and LH, SHBG, TT and cFT levels were evaluated after six months (T4). In six patients, sexual function was evaluated before (T3) and after (T4) ART using the International Index of Erectile Function-15 (IIEF-15) questionnaire.
    Results: Under AMT we observed higher SHBG and LH and lower cFT levels at T1-T3 compared to T0 (all p<0.05). At T3, hypergonadotropic hypogonadism and erectile dysfunction (ED) were detected in 80% and 83.3% of cases. At T4, we observed a significant cFT increase in men treated with T gel, and a significant improvement in IIEF-15 total and subdomains scores and ED prevalence (16.7%) in men under ART.
    Conclusion: AMT was associated with hypergonatropic hypogonadism and ED, while ART led to a significant improvement of cFT levels and sexual function in the hypogonadal ACC patients. Therefore, we suggest to evaluate LH, SHBG, TT and cFT and sexual function during AMT, and start ART in the hypogonadal ACC patients with sexual dysfunction.
    MeSH term(s) Humans ; Male ; Mitotane/therapeutic use ; Adrenocortical Carcinoma ; Retrospective Studies ; Testosterone ; Erectile Dysfunction ; Luteinizing Hormone ; Adrenal Cortex Neoplasms ; Hypogonadism/drug therapy
    Chemical Substances Mitotane (78E4J5IB5J) ; Testosterone (3XMK78S47O) ; Luteinizing Hormone (9002-67-9)
    Language English
    Publishing date 2024-01-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1320722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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