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  1. Book: Adipose tissue and adipokines in health and disease

    Fantuzzi, Giamila / Braunschweig, Carol

    (Nutrition and health)

    2014  

    Author's details ed. by Giamila Fantuzzi ; Carol BRaunschweig
    Series title Nutrition and health
    Keywords Adipose Tissue / physiology ; Adipocytes / physiology ; Obesity / etiology ; Obesity / complications
    Language English
    Size XXVI, 372 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018295416
    ISBN 978-1-62703-769-3 ; 9781627037709 ; 1-62703-769-1 ; 1627037705
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 2373 available for loan (reading room) Lesesaal EG

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  2. Book: Adipose tissue and adipokines in health and disease

    Fantuzzi, Giamila

    (Nutrition and health)

    2007  

    Author's details ed. by Giamila Fantuzzi
    Series title Nutrition and health
    Keywords Adipose Tissue / physiology ; Adipocytes / physiology ; Obesity / etiology ; Obesity / complications
    Language English
    Size XXI, 397 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT014999400
    ISBN 1-58829-721-7 ; 978-1-58829-721-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 2767 order for loan Magazin

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  3. Book: Cytokine knockouts

    Fantuzzi, Giamila

    (Contemporary immunology)

    2003  

    Author's details ed. by Giamila Fantuzzi
    Series title Contemporary immunology
    Language English
    Size XIX, 471 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT013835952
    ISBN 1-58829-194-4 ; 978-1-58829-194-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 A 4335 order for loan Magazin

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  4. Article ; Online: Perspective: Daniela Novick, cytokines and their receptors.

    Ghezzi, Pietro / Fantuzzi, Giamila / Dinarello, Charles A

    Frontiers in immunology

    2023  Volume 14, Page(s) 1160651

    Abstract: This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several ... ...

    Abstract This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several cytokines, including tumor necrosis factor, interleukin (IL) 6, IL-18 and IL-32. Importantly, her work has been key in the development of monoclonal antibodies against interferons and cytokines. This Perspective discusses her contribution to the field and highlights her recent review on this topic.
    MeSH term(s) Female ; Humans ; Cytokines/metabolism ; Interleukin-6/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interferons ; Antibodies, Monoclonal/therapeutic use
    Chemical Substances Cytokines ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interferons (9008-11-1) ; Antibodies, Monoclonal
    Language English
    Publishing date 2023-05-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1160651
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cancer is a propagandist.

    Fantuzzi, Giamila

    Studies in history and philosophy of biological and biomedical sciences

    2017  Volume 63, Page(s) 28–31

    Abstract: Communication among cells (also known as cross-talk) plays a prominent role in the current knowledge of the pathophysiology of cancer and of cancer-associated conditions such as paraneoplastic syndromes and cachexia that are responsible for much of ... ...

    Abstract Communication among cells (also known as cross-talk) plays a prominent role in the current knowledge of the pathophysiology of cancer and of cancer-associated conditions such as paraneoplastic syndromes and cachexia that are responsible for much of cancer's morbidity and mortality. Yet, biomedical scientists lack an explicit unifying frame that places this exchange of molecular information at the core of their understanding of cancer as a systemic disease. Propaganda is a type of information that aims at misleading, a form of communication intended primarily to serve the messenger. The biased molecular cross-talk between cancer and non-cancer cells can be considered as a form of biological propaganda. I here propose cancer is a propagandist as a metaphor that may serve as a unifying frame to interpret both cancer and cancer-associated syndromes under the same communication-based concept and may thus serve to bring together research that is currently compartmentalized under separate disciplines.
    Language English
    Publishing date 2017-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1500765-0
    ISSN 1879-2499 ; 1369-8486
    ISSN (online) 1879-2499
    ISSN 1369-8486
    DOI 10.1016/j.shpsc.2017.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Adipose Tissue and Adipokines in Health and Disease

    Fantuzzi, Giamila / Mazzone, Theodore

    2007  

    Author's details edited by Giamila Fantuzzi, Theodore Mazzone
    Keywords Diabetes ; Endocrinology ; Gastroenterology ; Human physiology ; Nutrition
    Language English
    Publisher Humana Press Inc
    Publishing place Totowa, NJ
    Document type Book ; Online
    HBZ-ID TT050387148
    ISBN 978-1-588-29721-1 ; 978-1-597-45370-7 ; 1-588-29721-7 ; 1-597-45370-6
    DOI 10.1007/978-1-59745-370-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

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  7. Article ; Online: C-reactive protein as the biomarker of choice to monitor the effects of exercise on inflammation in Parkinson's disease.

    Mehta, Niyati / Luthra, Nijee S / Corcos, Daniel M / Fantuzzi, Giamila

    Frontiers in immunology

    2023  Volume 14, Page(s) 1178448

    Abstract: Parkinson's disease (PD), a heterogeneous disease with no disease-modifying treatments available, is the fastest growing neurological disease worldwide. Currently, physical exercise is the most promising treatment to slow disease progression, with ... ...

    Abstract Parkinson's disease (PD), a heterogeneous disease with no disease-modifying treatments available, is the fastest growing neurological disease worldwide. Currently, physical exercise is the most promising treatment to slow disease progression, with evidence suggesting it is neuroprotective in animal models. The onset, progression, and symptom severity of PD are associated with low grade, chronic inflammation which can be quantified by measuring inflammatory biomarkers. In this perspective, we argue that C-reactive protein (CRP) should be used as the primary biomarker for monitoring inflammation and therefore disease progression and severity, particularly in studies examining the impact of an intervention on the signs and symptoms of PD. CRP is the most studied biomarker of inflammation, and it can be detected using relatively well-standardized assays with a wide range of detection, allowing for comparability across studies while generating robust data. An additional advantage of CRP is its ability to detect inflammation irrespective of its origin and specific pathways, an advantageous characteristic when the cause of inflammation remains unknown, such as PD and other chronic, heterogeneous diseases.
    MeSH term(s) Animals ; Parkinson Disease/diagnosis ; Parkinson Disease/metabolism ; C-Reactive Protein/metabolism ; Biomarkers ; Inflammation/complications ; Exercise ; Disease Progression
    Chemical Substances C-Reactive Protein (9007-41-4) ; Biomarkers
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1178448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The sound of health.

    Fantuzzi, Giamila

    Frontiers in immunology

    2014  Volume 5, Page(s) 351

    Language English
    Publishing date 2014-07-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2014.00351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Health versus disease as the catalyst for biomedical research: the science of adipokines as a case in point.

    Fantuzzi, Giamila

    Frontiers in endocrinology

    2014  Volume 5, Page(s) 136

    Language English
    Publishing date 2014-08-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2014.00136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Adiponectin in inflammatory and immune-mediated diseases.

    Fantuzzi, Giamila

    Cytokine

    2013  Volume 64, Issue 1, Page(s) 1–10

    Abstract: Circulating levels of adiponectin (APN) are reduced in obesity and associated comorbidities, with inflammation playing an important role in downregulating APN production. In contrast to obesity and metabolic disease, elevated systemic and local levels of ...

    Abstract Circulating levels of adiponectin (APN) are reduced in obesity and associated comorbidities, with inflammation playing an important role in downregulating APN production. In contrast to obesity and metabolic disease, elevated systemic and local levels of APN are present in patients with inflammatory and immune-mediated diseases, including autoimmune and pulmonary conditions, heart and kidney failure, viral hepatitis, organ transplantation and perhaps critical illness. A positive association between inflammation and APN is usually reported in inflammatory/immune pathologies, in contrast with the negative correlation typical of metabolic disease. This review discusses the role of APN in modulation of inflammation and immunity and the potential mechanisms leading to increased levels of APN in inflammatory/immune diseases, including modification of adipose tissue physiology; relative contribution of different tissues and adipose depots; hormonal, pharmacological, nutritional and life style factors; the potential contribution of the microbiota as well as the role of altered APN clearance and release from T-cadherin-associated tissue reservoirs. Potential reasons for some of the apparently contradictory findings on the role of APN as a modulator of immunity and inflammation are also discussed, including a comparison of types of recombinant APN used for in vitro studies and strain-dependent differences in the phenotype of APN KO mice.
    MeSH term(s) Adiponectin/blood ; Adiponectin/genetics ; Adiponectin/metabolism ; Adipose Tissue/metabolism ; Animals ; Disease Models, Animal ; Heart Diseases/blood ; Heart Diseases/metabolism ; Humans ; Immune System Diseases/blood ; Immune System Diseases/immunology ; Inflammation/immunology ; Lung Diseases/blood ; Lung Diseases/metabolism ; Mice ; Mice, Knockout ; Obesity/blood ; Obesity/metabolism ; Organ Transplantation ; Renal Insufficiency/blood ; Renal Insufficiency/metabolism
    Chemical Substances Adiponectin
    Language English
    Publishing date 2013-07-11
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1018055-2
    ISSN 1096-0023 ; 1043-4666
    ISSN (online) 1096-0023
    ISSN 1043-4666
    DOI 10.1016/j.cyto.2013.06.317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2840: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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